AstraZeneca Joins Other Drugmakers in Deal with Trump; Stock Declines Yet Outperforms Market.
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Oct 10 2025
0mins
Source: MarketWatch
AstraZeneca's Upcoming Deal: AstraZeneca PLC is expected to announce a deal with U.S. President Donald Trump aimed at lowering drug prices, similar to a recent agreement made by Pfizer Inc.
Pfizer's Agreement Details: Last week, Pfizer and Trump established an agreement that includes a three-year tariff exemption in exchange for reduced drug prices and participation in the new direct-to-consumer website, TrumpRx.gov.
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Analyst Views on PFE
Wall Street analysts forecast PFE stock price to rise
16 Analyst Rating
5 Buy
11 Hold
0 Sell
Moderate Buy
Current: 27.770
Low
24.00
Averages
28.56
High
35.00
Current: 27.770
Low
24.00
Averages
28.56
High
35.00
About PFE
Pfizer Inc. is a research-based, global biopharmaceutical company. The Company is engaged in the discovery, development, manufacture, marketing, sale and distribution of biopharmaceutical products worldwide. Its Biopharma segment includes the Pfizer U.S. Commercial Division, and the Pfizer International Commercial Division. Its product categories include oncology, primary care and specialty care. Its oncology products include Ibrance, Xtandi, Padcev, Adcetris, Inlyta, Lorbrena, Bosulif, Tukysa, Braftovi, Mektovi, Orgovyx, Elrexfio, Tivdak and Talzenna. Its primary care products include Eliquis, Nurtec ODT/Vydura, Zavzpret, the Prevnar family, Comirnaty, Abrysvo, FSME/IMMUN-TicoVac, Nimenrix, Trumenba, and Paxlovid. Its specialty care products include Xeljanz, Enbrel (outside the United States and Canada), Inflectra, Abrilada, Cibinqo, Litfulo, Eucrisa, Velsipity, the Vyndaqel family, Genotropin, and others. Its PF-08653944 is an ultra-long-acting fully biased GLP-1 receptor agonist.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Research Site Closure: Pfizer is set to close its South San Francisco research site and office by the end of April, indicating a significant pullback from the Bay Area's biotech sector, which could impact its market position in the region.
- Employee Transition: The company laid off 52 employees at this location, and while the exact number of employees at 181 Oyster Point Blvd. is unclear, all designated staff will transition to remote roles, reflecting a reassessment of office space utilization.
- Market Implications: This decision may suggest that the New York-based pharmaceutical giant is ending its presence in the Bay Area, indicating a potential decline in confidence in the local biotech market, which could affect future investments and partnerships.
- Continued California Operations: Despite the closure of the South San Francisco office, Pfizer maintains a strong presence in California, including facilities in San Diego, demonstrating the company's ongoing commitment to the state's market potential.
See More
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- Policy Shift Outlook: The FDA is likely to permit compounding pharmacies to sell injectable peptides again, a move that would be a victory for HHS Secretary Robert F. Kennedy Jr., despite opposition from many senior FDA officials regarding the safety of these products.
- Safety Risk Alerts: The FDA's updated list of banned peptides includes cesium chloride and chloral hydrate, with the former linked to irregular heartbeat and the latter associated with dosing errors and oversedation, highlighting significant safety concerns surrounding these substances.
- Regulatory Review Meeting: The FDA plans to schedule a meeting of its Pharmacy Compounding Advisory Committee to discuss medical evidence for the peptides and vote on whether to allow pharmacies to resume production, indicating a serious regulatory focus on product safety.
- Market Condition Analysis: Scott Brunner, CEO of the Alliance for Pharmacy Compounding, expressed concerns that consumers are likely purchasing unproven illicit products or research-grade items, as there are no pharmaceutical-grade versions available from FDA-registered manufacturers, illustrating the chaotic state of the market and lack of effective oversight.
See More
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- Increased Withdrawals: In the ten months following Trump's executive order, the number of brands with at least one pack withdrawn from the European market rose by 43%, suggesting that drugmakers may face a dilemma between maintaining access in lower-priced EU markets and ensuring U.S. pricing integrity.
- Policy Impact Assessment: While other factors could contribute to changes in drug launches and withdrawals, GlobalData notes that this trend may serve as an early signal of the impact that the introduction of International Reference Pricing in the U.S. may have on European markets, raising concerns about patient access and affordability.
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See More
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- Technical Analysis Tool: Comparing the latest share price to the 200-day moving average can provide valuable insights for investors, helping them assess market trends and potential buying opportunities.
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See More
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See More
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Eli Lilly's AI Integration: Eli Lilly is positioning itself as a leader in the healthcare industry's integration of artificial intelligence, indicating it has been proactive in this area.
Industry Response: The healthcare sector is currently working to adopt AI technologies, highlighting a broader trend towards innovation in medical practices.
See More
