Amgen Reports Positive Phase 3 Results for TEPEZZA in Thyroid Eye Disease
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Apr 06 2026
0mins
Should l Buy AMGN?
Source: NASDAQ.COM
- Clinical Trial Success: Amgen's TEPEZZA demonstrated a 77% proptosis response rate in its Phase 3 trial for moderate-to-severe active Thyroid Eye Disease, significantly outperforming the 19.6% response in the placebo group, indicating substantial therapeutic efficacy for this rare autoimmune condition.
- Consistent Safety Profile: The overall safety results were consistent with TEPEZZA's known safety profile, suggesting that the new subcutaneous administration method does not introduce significant safety concerns, thereby enhancing market acceptance and patient confidence.
- Innovative Delivery Method: TEPEZZA's subcutaneous injection provides IV-level efficacy, expanding its potential application among Thyroid Eye Disease patients and likely attracting more patients to this delivery method.
- Stable Market Performance: Amgen's stock has fluctuated between $261.43 and $391.29 over the past year, currently trading at $344.33, down 1.04%, yet overall performance reflects market optimism regarding its new treatment options.
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Analyst Views on AMGN
Wall Street analysts forecast AMGN stock price to rise
24 Analyst Rating
14 Buy
9 Hold
1 Sell
Moderate Buy
Current: 349.390
Low
280.00
Averages
363.10
High
425.00
Current: 349.390
Low
280.00
Averages
363.10
High
425.00
About AMGN
Amgen Inc. is a biotechnology company. It discovers, develops, manufactures and delivers medicines for the toughest diseases. It focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve people’s lives. It operates in the human therapeutics segment. Its marketed products portfolio includes EPOGEN (epoetin alfa); Aranesp (darbepoetin alfa); Parsabiv (etelcalcetide); Neulasta (pegfilgrastim); KANJINTI (trastuzumab-anns); Otezla; BLINCYTO (blinatumomab); ACTIMMUNE (interferon gamma-1b); Neulasta (pegfilgrastim); Sensipar/Mimpara (cinacalcet); Prolia (denosumab); ENBREL; QUINSAIR (levofloxacin); Repatha (evolocumab) and others. It markets ENBREL, a tumor necrosis factor blocker, in the United States and Canada. It markets Otezla, a small molecule that inhibits phosphodiesterase 4, in many countries around the world. It markets Repatha, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, in many countries around the world.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Earnings Forecast: The company is expected to report an EPS of $4.76 in its earnings release on April 30, 2026, representing a 2.86% decline from the same quarter last year, which may impact investor confidence.
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- Dual-Targeting Strategy: The study will combine Zai Lab's zocilurtatug pelitecan with Amgen's IMDELLTRA, aiming to enhance clinical responses and address potential resistance pathways through complementary mechanisms, thereby improving survival chances for patients.
- Clinical Trial Progress: Zocilurtatug pelitecan has demonstrated a high response rate and a tolerable safety profile in heavily pretreated SCLC patients, indicating its therapeutic potential, especially with FDA orphan drug and fast track designations.
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- Biosimilar Market Expansion: Teva plans to launch six new biosimilars in 2026 and 2027, potentially competing with Amgen and Johnson & Johnson, which will further solidify its position as the second-largest player in the biosimilar market.
- Investor Confidence Boost: Analysts are optimistic about Teva's future, with 12 out of 15 analysts rating the stock as a
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- Biosimilar Expansion: Teva plans to launch six new biosimilars in 2026 and 2027, further solidifying its position as the second-largest player in the biosimilar market, with anticipated competition against giants like Amgen and Johnson & Johnson, driving future revenue growth.
- Market Risk Factors: Despite several catalysts propelling stock price growth, a market crash or significant pipeline issues could derail Teva's momentum; however, the company's pipeline is relatively de-risked, and with a forward P/E of only 11.7, it presents a compelling value investment opportunity.
See More
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- Market Potential: Approximately 160,000 patients are diagnosed with small cell lung cancer in China each year, accounting for nearly 15% of global lung cancer cases, providing a substantial market opportunity for tarlatamab, especially given the limited efficacy of existing treatments.
- Treatment Need: Despite platinum-based chemotherapy being the main first-line therapy, the majority of small cell lung cancer patients experience disease progression within six months, thus the approval of tarlatamab offers a new treatment option that could potentially improve survival rates and quality of life for these patients.
- Collaboration Background: BeOne Medicines has been developing tarlatamab in Mainland China under a licensing agreement with Amgen since 2019, and this approval not only strengthens the partnership between the two companies but also lays a foundation for BeOne's further development in the biopharmaceutical sector.
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- Technical Analysis Tool: Comparing the latest share price to the 200-day moving average provides investors with valuable insights for technical analysis, aiding in the assessment of market trends and potential buy or sell opportunities.
- ETF Unit Trading Mechanism: ETFs trade like stocks, where investors buy and sell 'units' that can be created or destroyed based on investor demand, impacting the liquidity and market performance of the ETF.
- Inflows and Outflows Monitoring: Weekly monitoring of changes in shares outstanding helps identify ETFs experiencing notable inflows (new units created) or outflows (old units destroyed), assessing their impact on underlying assets and overall market dynamics.
See More
