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AMGN Should I Buy

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Intellectia

Should You Buy Amgen Inc (AMGN) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
350.640
1 Day change
0.54%
52 Week Range
391.290
Analysis Updated At
2026/03/26
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Amgen Inc (AMGN) is not a strong buy at the moment for a beginner investor with a long-term horizon. While the company has shown strong financial performance in the latest quarter and has potential long-term growth catalysts, the current technical indicators and trading sentiment do not suggest an optimal entry point. Additionally, insider selling and the lack of significant positive momentum in the stock price further support a hold recommendation.

Technical Analysis

The MACD histogram is negative (-2.512) and contracting, indicating weak momentum. RSI is neutral at 39.778, and moving averages are converging, showing no clear trend. The stock is trading near its pivot level (357.579), with resistance at 368.287 and support at 346.872.

Options Data

Bullish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
7
Buy
4

Positive Catalysts

  • Amgen's financials for Q4 2025 showed strong YoY growth in revenue (8.58%), net income (112.60%), and EPS (112.07%). Gross margin also improved to 72.88%. Analysts highlight potential long-term growth from new drugs and mechanisms targeting Myasthenia Gravis and other conditions.

Neutral/Negative Catalysts

  • Insiders are selling heavily, with a 475.47% increase in selling activity over the last month. The stock has run up about 35% over the past six months, and some analysts believe it is fairly valued at current levels. Technical indicators do not show strong upward momentum.

Financial Performance

Amgen's Q4 2025 financials were strong, with revenue increasing to $9.87 billion (up 8.58% YoY), net income rising to $1.33 billion (up 112.60% YoY), and EPS growing to 2.46 (up 112.07% YoY). Gross margin improved to 72.88%, up 10.84% YoY.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts have mixed views. Wells Fargo raised its price target to $390, citing upside potential from new drugs, while Jefferies initiated coverage with a Hold rating and a $350 price target, considering the stock fairly valued. Piper Sandler and TD Cowen remain bullish with price targets of $432 and $420, respectively, while Freedom Capital downgraded the stock to Hold, citing fair valuation.

Wall Street analysts forecast AMGN stock price to rise
24 Analyst Rating
Wall Street analysts forecast AMGN stock price to rise
14 Buy
9 Hold
1 Sell
Moderate Buy
Current: 348.770
sliders
Low
280
Averages
363.1
High
425
Current: 348.770
sliders
Low
280
Averages
363.1
High
425
Wells Fargo
Equal Weight
maintain
$375 -> $390
AI Analysis
2026-03-19
Reason
Wells Fargo
Price Target
$375 -> $390
AI Analysis
2026-03-19
maintain
Equal Weight
Reason
Wells Fargo raised the firm's price target on Amgen to $390 from $375 and keeps an Equal Weight rating on the shares. The firm thinks new drugs and mechanisms such as CD20, BAFF/APRILs, and next generation complement Inhibitors have potential to expand the generalized Myasthenia Gravis market by more than threefold in the next 10 years, to $15B U.S. and $20B global sales in 2036. Vertex Pharmaceuticals (VRTX), Amgen (AMGN) and Regeneron (REGN) could be the biggest beneficiaries here, and Wells is of the view that there is upside to Street numbers.
Jefferies
Hold
initiated
$350
2026-03-10
Reason
Jefferies
Price Target
$350
2026-03-10
initiated
Hold
Reason
Jefferies initiated coverage of Amgen with a Hold rating and $350 price target. With the stock having run up about 35% over the past six months, driven by excellent near-term commercial execution, removal of regulatory overhangs and the macro environment, the firm thinks the stock looks fairly valued at current levels, the analyst tells investors.
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