Adagio Medical Holdings, Inc. Receives FDA Breakthrough Device Designation for the vCLASTM Cryoablation System
Breakthrough Device Designation: Adagio Medical has received FDA Breakthrough Device designation for its vCLAS™ Cryoablation System, aimed at treating drug-refractory ventricular tachycardia (VT), which allows for priority review and faster access to the device for patients.
Clinical Study and Technology: The vCLAS™ system utilizes proprietary Ultra-Low Temperature Cryoablation technology and is currently being evaluated in a clinical study (FULCRUM-VT) to support its application for FDA premarket approval, with the goal of improving treatment outcomes for patients with VT.
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Highlights from the Small Cap Growth Virtual Investor Conference
- On-Demand Viewing: Presentations from the Small Cap Growth Virtual Investor Conference held on February 5, 2026, are now available for on-demand viewing for 90 days, enhancing investor engagement and understanding of participating companies.
- 1x1 Meeting Requests: Selected companies are accepting one-on-one management meeting requests until February 10, providing investors with direct access to executives, which could facilitate informed investment decisions and potential capital inflows.
- Diverse Company Participation: The conference featured presentations from various companies, including Betolar Oyj, Envoy Medical Inc., and C-COM Satellite Systems Inc., showcasing a wide range of investment opportunities in the small-cap growth sector, attracting diverse investor interest.
- Advantages of Virtual Conferences: Virtual Investor Conferences offer a real-time interactive platform that enhances connections between companies and investors, improving the investor experience and creating more efficient fundraising and marketing opportunities for participating firms.
Highlights from the Small Cap Growth Virtual Investor Conference
- On-Demand Content: Presentations from the Small Cap Growth Virtual Investor Conference held on February 5, 2026, are now available for on-demand viewing, allowing investors to access content 24/7 for 90 days, thereby increasing attention on small-cap growth companies.
- Investor Participation: The conference invites individual and institutional investors, advisors, and analysts to participate, providing an interactive platform that facilitates direct communication between investors and companies, enhancing investor relations management.
- One-on-One Meeting Opportunities: Selected companies are accepting one-on-one management meeting requests until February 10, offering investors a chance to engage directly with company executives, which deepens investor engagement and trust.
- Advantages of Virtual Conferences: Virtual Investor Conferences replicate the components of on-site investor meetings through real-time investor engagement solutions, enhancing the efficiency of connections between companies and investors and modernizing investor communications.
Agenda Released for Small Cap Growth Virtual Investor Conference
- Conference Schedule: The Small Cap Growth Virtual Investor Conference is set for February 5, featuring a diverse lineup of innovative companies, aimed at providing investors direct access to the small-cap market, thereby enhancing interaction and engagement with companies.
- Participant Invitation: The conference invites individual investors, institutional investors, advisors, and analysts to attend at no cost, aiming to streamline the registration process and system checks to enhance participation efficiency and ensure timely updates for investors.
- Company Showcase Opportunity: Jason Paltrowitz, Executive Vice President at OTC Markets Group, emphasized that the conference will highlight a diverse roster of companies, showcasing innovation in the small-cap market and helping firms effectively communicate their growth narratives to bolster investor confidence.
- Investor Relations Facilitation: Virtual Investor Conferences provide a real-time investor engagement solution, allowing companies to communicate directly with a global investor audience, schedule one-on-one meetings, and enhance presentation effectiveness, thus accelerating the next phase of investor participation.
Insider Buying Update for Wednesday, December 17: SRRK, ADGM
Insider Purchase at Scholar Rock: Srinivas Akkaraju bought 29,599 shares of Scholar Rock Holding (SRRK) for $1.18M at $39.92 each, seeing a 13.5% gain during the trading session.
Previous Investment by Akkaraju: Prior to this purchase, Akkaraju had acquired $18.81M worth of shares at $37.58 each within the last year.
Adagio Medical Holdings CEO Purchase: Todd Usen, CEO of Adagio Medical Holdings, purchased 207,315 shares for $225,973 at $1.09 each, while the stock was down about 2.5% on the day.
Market Performance: Scholar Rock Holding's stock was up approximately 0.4% on Wednesday, with SRRK reaching a high of $45.32 during trading.
B. Riley Financial Shares Surge Approximately 25%; Check Out 20 Stocks Making Moves in Premarket Trading
B. Riley Financial Performance: B. Riley Financial Inc reported a significant turnaround with earnings of $4.50 per share for Q2, compared to a loss of $14.35 per share a year ago, and sales increased to $225.302 million from $94.885 million, leading to a 25% rise in share price during pre-market trading.
Pre-Market Stock Movements: Several stocks experienced notable pre-market trading movements, with Biodexa Pharmaceuticals gaining 51.4% and Venus Concept surging 31.1%, while Radiopharm Theranostics saw a sharp decline of 39.8%.
Other Notable Gainers: Other stocks that rose in pre-market trading included Uniqure NV (+14.1%), Adagio Medical Holdings (+11.7%), and Sunrise New Energy (+10.5%), reflecting a mix of recovery and growth in various sectors.
Significant Losers: Stocks that faced declines included iRobot Corp, which fell 23.2% after filing for Chapter 11 bankruptcy, and Saverone 2014 Ltd, which tumbled 37.8% following a previous gain, indicating volatility in the market.
Adagio Medical Presents Initial Acute Findings from FULCRUM-VT U.S. Pivotal Study During Late Breaking Session at VT Symposium
Study Results: Adagio Medical's FULCRUM-VT Study reported a 97.4% acute success rate for Ultralow Temperature Cryoablation (ULTC) in treating Sustained Monomorphic Ventricular Tachycardia (SMVT) among 207 patients, with a 2.5% rate of major adverse events.
Future Implications: The promising preliminary results suggest that ULTC could transform treatment for ventricular tachycardia, with long-term outcomes and further effectiveness analysis expected to be shared at future conferences.
Highlights from the Small Cap Growth Virtual Investor Conference
- On-Demand Viewing: Presentations from the Small Cap Growth Virtual Investor Conference held on February 5, 2026, are now available for on-demand viewing for 90 days, enhancing investor engagement and understanding of participating companies.
- 1x1 Meeting Requests: Selected companies are accepting one-on-one management meeting requests until February 10, providing investors with direct access to executives, which could facilitate informed investment decisions and potential capital inflows.
- Diverse Company Participation: The conference featured presentations from various companies, including Betolar Oyj, Envoy Medical Inc., and C-COM Satellite Systems Inc., showcasing a wide range of investment opportunities in the small-cap growth sector, attracting diverse investor interest.
- Advantages of Virtual Conferences: Virtual Investor Conferences offer a real-time interactive platform that enhances connections between companies and investors, improving the investor experience and creating more efficient fundraising and marketing opportunities for participating firms.
Highlights from the Small Cap Growth Virtual Investor Conference
- On-Demand Content: Presentations from the Small Cap Growth Virtual Investor Conference held on February 5, 2026, are now available for on-demand viewing, allowing investors to access content 24/7 for 90 days, thereby increasing attention on small-cap growth companies.
- Investor Participation: The conference invites individual and institutional investors, advisors, and analysts to participate, providing an interactive platform that facilitates direct communication between investors and companies, enhancing investor relations management.
- One-on-One Meeting Opportunities: Selected companies are accepting one-on-one management meeting requests until February 10, offering investors a chance to engage directly with company executives, which deepens investor engagement and trust.
- Advantages of Virtual Conferences: Virtual Investor Conferences replicate the components of on-site investor meetings through real-time investor engagement solutions, enhancing the efficiency of connections between companies and investors and modernizing investor communications.
Agenda Released for Small Cap Growth Virtual Investor Conference
- Conference Schedule: The Small Cap Growth Virtual Investor Conference is set for February 5, featuring a diverse lineup of innovative companies, aimed at providing investors direct access to the small-cap market, thereby enhancing interaction and engagement with companies.
- Participant Invitation: The conference invites individual investors, institutional investors, advisors, and analysts to attend at no cost, aiming to streamline the registration process and system checks to enhance participation efficiency and ensure timely updates for investors.
- Company Showcase Opportunity: Jason Paltrowitz, Executive Vice President at OTC Markets Group, emphasized that the conference will highlight a diverse roster of companies, showcasing innovation in the small-cap market and helping firms effectively communicate their growth narratives to bolster investor confidence.
- Investor Relations Facilitation: Virtual Investor Conferences provide a real-time investor engagement solution, allowing companies to communicate directly with a global investor audience, schedule one-on-one meetings, and enhance presentation effectiveness, thus accelerating the next phase of investor participation.
Insider Buying Update for Wednesday, December 17: SRRK, ADGM
Insider Purchase at Scholar Rock: Srinivas Akkaraju bought 29,599 shares of Scholar Rock Holding (SRRK) for $1.18M at $39.92 each, seeing a 13.5% gain during the trading session.
Previous Investment by Akkaraju: Prior to this purchase, Akkaraju had acquired $18.81M worth of shares at $37.58 each within the last year.
Adagio Medical Holdings CEO Purchase: Todd Usen, CEO of Adagio Medical Holdings, purchased 207,315 shares for $225,973 at $1.09 each, while the stock was down about 2.5% on the day.
Market Performance: Scholar Rock Holding's stock was up approximately 0.4% on Wednesday, with SRRK reaching a high of $45.32 during trading.
B. Riley Financial Shares Surge Approximately 25%; Check Out 20 Stocks Making Moves in Premarket Trading
B. Riley Financial Performance: B. Riley Financial Inc reported a significant turnaround with earnings of $4.50 per share for Q2, compared to a loss of $14.35 per share a year ago, and sales increased to $225.302 million from $94.885 million, leading to a 25% rise in share price during pre-market trading.
Pre-Market Stock Movements: Several stocks experienced notable pre-market trading movements, with Biodexa Pharmaceuticals gaining 51.4% and Venus Concept surging 31.1%, while Radiopharm Theranostics saw a sharp decline of 39.8%.
Other Notable Gainers: Other stocks that rose in pre-market trading included Uniqure NV (+14.1%), Adagio Medical Holdings (+11.7%), and Sunrise New Energy (+10.5%), reflecting a mix of recovery and growth in various sectors.
Significant Losers: Stocks that faced declines included iRobot Corp, which fell 23.2% after filing for Chapter 11 bankruptcy, and Saverone 2014 Ltd, which tumbled 37.8% following a previous gain, indicating volatility in the market.
Adagio Medical Presents Initial Acute Findings from FULCRUM-VT U.S. Pivotal Study During Late Breaking Session at VT Symposium
Study Results: Adagio Medical's FULCRUM-VT Study reported a 97.4% acute success rate for Ultralow Temperature Cryoablation (ULTC) in treating Sustained Monomorphic Ventricular Tachycardia (SMVT) among 207 patients, with a 2.5% rate of major adverse events.
Future Implications: The promising preliminary results suggest that ULTC could transform treatment for ventricular tachycardia, with long-term outcomes and further effectiveness analysis expected to be shared at future conferences.
