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ADGM Overview

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ET
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Intellectia

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High
0.798
Open
0.710
VWAP
0.74
Vol
79.10K
Mkt Cap
16.08M
Low
0.710
Amount
58.86K
EV/EBITDA(TTM)
--
Total Shares
22.21M
EV
--
EV/OCF(TTM)
--
P/S(TTM)
--
Adagio Medical Holdings, Inc. is a medical device company. The Company is focused on developing and commercializing products for the treatment of cardiac arrhythmias with catheter-based ultra-low temperature ablation (ULTA) technology, formerly known as ultra-low temperature cryoablation (ULTC) technology. Its initial focus is on the treatment of ventricular tachycardia (VT), which is a rapid, abnormal heart rhythm, or arrhythmia, that originates in the heart’s lower chambers, or ventricles, potentially leading to impaired blood flow and, if sustained, it can be fatal. Its ULTA products are purpose-built to treat patients with VT and are designed to address the unique anatomy of the ventricle and the specific needs of the VT patient. Its catheters and consoles are designed to create titratable, large, durable, deep lesions within the ventricle through a stable, endocardial or inside the heart approach with no required irrigation.
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Events Timeline

(ET)
2026-05-21
08:10:00
Adagio Medical Submits PMA Application for vCLAS System to FDA
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2026-05-12 (ET)
2026-05-12
08:10:00
Adagio Medical Achieves Landmark Progress in Q1 2026 with ULTA Platform
select
2026-04-26 (ET)
2026-04-26
13:30:00
Adagio Medical Reports Six-Month Results from Fulcrum-VT Clinical Trial
select
2026-04-08 (ET)
2026-04-08
08:10:00
Adagio Medical Receives FDA Approval to Expand FULCRUM-VT Trial
select
2026-03-27 (ET)
2026-03-27
08:10:00
Adagio Completes Enrollment of 209 Patients in FULCRUM-VT Trial
select
2026-03-24 (ET)
2026-03-24
08:20:00
Adagio Medical Publishes Pre-Clinical Results of Ultra-Low Temperature Ablation Technology
select
2026-02-04 (ET)
2026-02-04
09:20:00
Adagio Medical Publishes Results of Ultrawlow Temperature Cardiac Ablation Study
select

News

Newsfilter
8.5
05-21Newsfilter
Adagio Submits PMA Application for vCLAS System
  • Clinical Trial Success: The FULCRUM-VT trial enrolled 209 patients across 20 leading centers, achieving a 97.4% acute clinical success rate, demonstrating the system's effectiveness in treating drug-refractory ventricular tachycardia, which is expected to significantly enhance treatment options for patients.
  • Significant Market Potential: The PMA application for the vCLAS system marks the first-ever submission of a purpose-built device in the ventricular ablation market, projected to reach $5.8 billion, positioning Adagio to capture market share and address unmet medical needs with this innovative technology.
  • Safety and Efficacy: Trial results indicated that 84.3% of patients experienced freedom from ICD shocks within six months, with only 2.4% major adverse events, highlighting the vCLAS system's superior safety and efficacy, which could redefine treatment standards in cardiology.
  • Strategic Implications: Adagio's CEO emphasized that this technology is not just a new approach to VT ablation but a fundamentally better solution aimed at providing uncompromised treatment for all eligible VT patients, signaling the company's leadership position in cardiac care.
seekingalpha
9.5
05-12seekingalpha
Adagio Medical Reports Q1 Financial Results with Reduced Losses
  • Financial Highlights: Adagio Medical Holdings reported a Q1 GAAP EPS of -$0.31, which, while still negative, shows improvement compared to -$0.21 in the same period of 2025, indicating gradual financial performance enhancement.
  • Reduced Net Loss: For the three months ended March 31, 2026, the company recorded a net loss of $7.0 million, down from $7.7 million in Q1 2025, suggesting progress in cost control and operational efficiency.
  • Expense Management: Selling, general, and administrative expenses for Q1 2026 totaled $2.5 million, significantly lower than $3.5 million in Q1 2025, primarily due to reductions in professional services, regulatory reporting, and payroll expenses, reflecting effective spending management.
  • Market Implications: Although still in a loss position, the improvement in EPS and effective cost control may boost investor confidence, potentially leading to a positive impact on stock price and indicating the company's future potential.
Newsfilter
2.0
04-26Newsfilter
FULCRUM-VT Trial Demonstrates Effectiveness of Cardiac Ablation Technology
  • Clinical Trial Results: The FULCRUM-VT trial demonstrated that 84% of patients experienced no ICD shocks within six months, and 59% had no VT recurrence, indicating the technology's effectiveness in cardiac patients and potentially changing treatment standards.
  • Safety Analysis: The trial reported a low major adverse event rate of only 2.4%, showcasing a favorable safety profile, with just 1.9% of patients readmitted for VT-related issues within six months, thereby reducing medical risks for patients.
  • Technological Innovation: Adagio's vCLAS ablation system showed equivalent effectiveness in both ischemic and non-ischemic cardiomyopathy patients, marking the first evidence of broad applicability across different pathological backgrounds, which may drive wider clinical adoption.
  • Market Potential: With approximately 300,000 sudden cardiac deaths due to ventricular arrhythmias annually in the U.S., the positive results from FULCRUM-VT provide a strong market entry opportunity for Adagio's ULTA technology, expected to attract more investment and improve patient outcomes.
moomoo
9.0
04-26moomoo
ADAGIO MEDICAL HOLDINGS INC - FULCRUM-VT TRIAL DEMONSTRATES 98% NON-INDUCIBILITY OF TARGETED VT AT PROCEDURE'S CONCLUSION
  • Trial Results: A recent trial by AGA Medical Holdings demonstrated a 98% non-inducibility of targeted VT at the end of the procedure.
  • Significance: These findings suggest a high efficacy of the treatment method being tested, indicating potential advancements in medical procedures related to VT.
NASDAQ.COM
9.0
04-08NASDAQ.COM
Adagio Medical Receives IDE Approval for vCLAS System Expansion
  • Clinical Trial Expansion: Adagio Medical has received Investigational Device Exemption (IDE) approval to expand its FULCRUM-VT trial, evaluating the next-generation vCLAS Ultra-Low Temperature Ablation System for treating sustained monomorphic ventricular tachycardia, marking a significant advancement in cardiac rhythm disorder treatment.
  • Technological Innovation: The vCLAS system aims to create effective lesions more efficiently by delivering ultra-cold temperatures around -170 °C, addressing the limitations of current ablation tools that struggle to achieve deep and durable lesions, thereby enhancing treatment outcomes.
  • Clinical Study Design: The expanded clinical sub-study will enroll up to 55 patients across multiple centers focusing on scar-mediated SMVT, intending to generate additional safety and effectiveness data to support the pivotal phase of the FULCRUM-VT trial.
  • Market Potential: Adagio executives stated that the IDE approval represents an important milestone in advancing technology that could broaden access to VT ablation, with the vCLAS Ultra catheter having the potential to become a scalable endocardial-only solution capable of treating a wide range of VT substrates.
Newsfilter
8.5
04-08Newsfilter
Adagio Receives FDA Approval to Expand Clinical Trial
  • Clinical Trial Expansion: Adagio Medical has received FDA approval to expand its FULCRUM-VT trial, evaluating the safety and efficacy of the next-generation vCLAS Ultra-Low Temperature Ablation System for treating Sustained Monomorphic Ventricular Tachycardia (SMVT), marking a significant advancement in cardiac treatment technology.
  • Technological Innovation: The new vCLASUltracatheter achieves ablation temperatures of approximately -170°C, significantly enhancing ablation efficiency and reducing ablation time by over 50%, which is expected to improve clinical workflow and patient treatment experience.
  • Market Potential: The IDE expansion approval enables Adagio to conduct a prospective, single-arm, multi-center study involving 55 patients, further validating the effectiveness of its technology and aiding the company's penetration and product promotion in the cardiac electrophysiology market.
  • Strategic Goals: Adagio aims to translate its ULTA technology into a widely applicable solution, targeting the treatment of a large underserved population suffering from ventricular tachycardia, thereby enhancing the company's leadership position in the cardiac medical device market.
Wall Street analysts forecast ADGM stock price to rise
1 Analyst Rating
Wall Street analysts forecast ADGM stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
4.00
Averages
4.00
High
4.00
Current: 0.000
sliders
Low
4.00
Averages
4.00
High
4.00
Piper Sandler
Matt O'Brien
Overweight
initiated
$3
AI Analysis
2026-04-14
Reason
Piper Sandler
Matt O'Brien
Price Target
$3
AI Analysis
2026-04-14
initiated
Overweight
Reason
Piper Sandler analyst Matt O'Brien initiated coverage of Adagio Medical with an Overweight rating and $3 price target. The firm says the company has developed a novel ultra-low temperature cryoablation technology for the treatment of ventricular tachycardia. Piper expects the pivotal results from the FULCRUM-VT trial should support FDA approval and commercial launch in 2027. The "large, underpenetrated" $1.6B domestic opportunity provides "ample opportunity" for sales growth potential and could deliver upside to expectations, contends Piper.
Lake Street
initiated
$4
2025-12-02
Reason
Lake Street
Price Target
$4
2025-12-02
initiated
Reason
Lake Street initiated coverage of Adagio Medical with a Buy rating and $4 price target. Adagio, which recently released top-line pivotal clinical data for its ultra-low temperature cryoablation vCLAS catheter for the "underserved" ventricular tachycardia ablation market, is approaching several "important value-creating catalysts," including the full FULCRUM-VT clinical data release due in the first half of 2026 and FDA approval that the firm expects in the second half of 2026, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ADGM
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Valuation Metrics

The current forward P/E ratio for Adagio Medical Holdings Inc (ADGM.O) is 0.00, compared to its 5-year average forward P/E of -0.07. For a more detailed relative valuation and DCF analysis to assess Adagio Medical Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.07
Current PE
0.00
Overvalued PE
0.18
Undervalued PE
-0.33

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.13
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.31
Undervalued EV/EBITDA
-0.57

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
1.78
Current PS
6.66
Overvalued PS
6.10
Undervalued PS
-2.53

Financials

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Frequently Asked Questions

What is Adagio Medical Holdings Inc (ADGM) stock price today?

The current price of ADGM is 0.724 USD — it has decreased -0.14

What is Adagio Medical Holdings Inc (ADGM)'s business?

Adagio Medical Holdings, Inc. is a medical device company. The Company is focused on developing and commercializing products for the treatment of cardiac arrhythmias with catheter-based ultra-low temperature ablation (ULTA) technology, formerly known as ultra-low temperature cryoablation (ULTC) technology. Its initial focus is on the treatment of ventricular tachycardia (VT), which is a rapid, abnormal heart rhythm, or arrhythmia, that originates in the heart’s lower chambers, or ventricles, potentially leading to impaired blood flow and, if sustained, it can be fatal. Its ULTA products are purpose-built to treat patients with VT and are designed to address the unique anatomy of the ventricle and the specific needs of the VT patient. Its catheters and consoles are designed to create titratable, large, durable, deep lesions within the ventricle through a stable, endocardial or inside the heart approach with no required irrigation.

What is the price predicton of ADGM Stock?

Wall Street analysts forecast ADGM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ADGM is4.00 USD with a low forecast of 4.00 USD and a high forecast of 4.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Adagio Medical Holdings Inc (ADGM)'s revenue for the last quarter?

Adagio Medical Holdings Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Adagio Medical Holdings Inc (ADGM)'s earnings per share (EPS) for the last quarter?

Adagio Medical Holdings Inc. EPS for the last quarter amounts to -0.31 USD, decreased -38.00

How many employees does Adagio Medical Holdings Inc (ADGM). have?

Adagio Medical Holdings Inc (ADGM) has 41 emplpoyees as of May 31 2026.

What is Adagio Medical Holdings Inc (ADGM) market cap?

Today ADGM has the market capitalization of 16.08M USD.