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SNTI Overview

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0.000
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Intellectia

Loading chart...

High
1.016
Open
0.997
VWAP
1.00
Vol
93.89K
Mkt Cap
26.11M
Low
0.985
Amount
93.73K
EV/EBITDA(TTM)
--
Total Shares
26.29M
EV
13.33M
EV/OCF(TTM)
--
P/S(TTM)
--
Senti Biosciences, Inc. and its subsidiaries is a clinical-stage biotechnology company developing next-generation cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The Company is leveraging its synthetic biology platform to engineer gene circuits into new medicines with enhanced precision and control. These gene circuits are designed to kill cancer cells, to spare healthy cells, to increase specificity to target tissues, and/or to be controllable even after administration. Its product candidates include SENTI-202 and SENTI-301A. SENTI-202 is a potential first-in-class Logic Gated off-the-shelf chimeric antigen receptor natural killer (CAR-NK) investigational cell therapy. SENTI-301A is a multi-armed off-the-shelf healthy donor-derived chimeric antigen receptor natural killer (CAR-NK) cell therapy product candidate designed for the treatment of GPC3 positive tumors.
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Events Timeline

(ET)
2026-02-11
08:40:00
Senti Biosciences Completes Enrollment for SENTI-202 Clinical Trial
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2025-12-09 (ET)
2025-12-09
07:10:00
Senti Biosciences Announces New Data from SENTI-202 Clinical Trial
select
2025-12-09
07:10:00
Senti Biosciences Receives RMAT Designation from FDA
select
2025-11-13 (ET)
2025-11-13
17:00:07
Senti Bio Announces Q3 Earnings Per Share of 69 Cents, Exceeding Consensus Estimate of 57 Cents
select
2025-08-12 (ET)
2025-08-12
09:16:33
Senti Bio releases virtual "What This Means" segment
select
2025-08-07 (ET)
2025-08-07
08:10:47
Senti Bio reports Q2 EPS (56c) vs. ($2.45) last year
select
2025-08-05 (ET)
2025-08-05
08:46:42
Senti Bio confirms recommended RP2D in Phase 1 study of SENTI-202
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News

Newsfilter
8.5
03-03Newsfilter
Senti Bio to Present at Global Healthcare Conference
  • Conference Presentation: Senti Biosciences' CEO Timothy Lu is set to present at the Leerink Partners Global Healthcare Conference in Miami on March 9, 2026, showcasing the company's advancements in cell and gene therapies, which is expected to attract investor and industry attention.
  • Platform Advantages: Leveraging its proprietary Gene Circuit platform, Senti Bio is developing next-generation cell and gene therapies aimed at precisely killing cancer cells while sparing healthy ones, thereby enhancing treatment safety and efficacy, which holds significant market potential.
  • Clinical Stage Progress: The company's pipeline includes cell therapies targeting challenging liquid and solid tumors, with preclinical studies demonstrating the effectiveness of its Gene Circuits in both NK and T cells, indicating broad applicability and potential clinical value of its technology.
  • Information Transparency: Senti Bio emphasizes communication with investors through its website and social media, ensuring timely updates and transparency of information, which enhances investor confidence and promotes public understanding of its technology.
Newsfilter
8.5
02-20Newsfilter
Senti Bio Participates in Cell & Gene Live Event on Innovative Therapies
  • Technology Sharing: Senti Bio participated in the Cell & Gene Live virtual event on February 19, 2026, where it showcased its Gene Circuit-based cell therapy technology, emphasizing its advantages in precision and functionality aimed at advancing the design and development of cell therapies.
  • Product Introduction: SENTI-202 is the first Logic Gated CAR-NK cell therapy product designed to target CD33 and FLT3 expressing hematologic malignancies, effectively eliminating leukemic cells while sparing healthy bone marrow cells, demonstrating significant therapeutic potential.
  • Clinical Trial Progress: Senti Bio is currently enrolling adult patients for a Phase 1 clinical trial of SENTI-202 targeting relapsed/refractory hematologic malignancies, which, if successful, could become the first allogeneic treatment for AML/MDS, presenting substantial market opportunities.
  • FDA Designation: SENTI-202 has received Orphan Drug and Regenerative Medicine Advanced Therapy designations from the FDA, indicating its potential in treating relapsed hematologic malignancies, thereby enhancing investor and market confidence.
Newsfilter
9.0
02-11Newsfilter
Senti Bio's SENTI-202 Clinical Data Shows Promising Results
  • Clinical Trial Milestone: Senti Bio announced the completion of enrollment in its Phase 1 clinical trial for SENTI-202, marking a significant advancement in treating relapsed or refractory acute myeloid leukemia (R/R AML), which is expected to lay the groundwork for subsequent pivotal registration studies.
  • Positive Clinical Data: At the American Society of Hematology (ASH) Annual Meeting, SENTI-202 demonstrated deep, MRD-negative, durable complete remissions with a favorable safety profile in heavily pretreated R/R AML patients, potentially boosting market confidence in this therapy.
  • FDA Discussion Preparation: The company plans to engage with the FDA in the first half of 2026 to discuss the pivotal registration program for SENTI-202 in R/R AML and the evaluation of additional indications, including newly diagnosed AML and pediatric AML, indicating the company's focus on future market opportunities.
  • RMAT Designation Advantage: SENTI-202 has received Regenerative Medicine Advanced Therapy (RMAT) designation, which may expedite its development and review process, thereby providing patients with faster treatment options and enhancing the company's competitive position in the market.
Globenewswire
5.0
2025-12-18Globenewswire
Senti Biosciences Grants New Employee 13,680 Stock Options at $1.31 Each
  • Stock Option Grant: On December 12, 2025, Senti Bio granted stock options for a total of 13,680 shares to a new employee at an exercise price of $1.31 per share, aimed at attracting and retaining talent to enhance the company's competitive edge in the biotechnology sector.
  • Incentive Plan Context: This stock option grant was made under the Amended and Restated 2022 Inducement Equity Plan adopted by the company on August 5, 2022, in compliance with NASDAQ Listing Rule 5635(c)(4), reflecting the company's commitment to talent acquisition.
  • Biotechnology Development: Senti Bio focuses on developing next-generation cell and gene therapies using its proprietary Gene Circuit platform, aiming to provide innovative treatment options for patients with incurable diseases, thereby advancing the company's technological progress in biomedicine.
  • Market Potential: By engineering Gene Circuits, Senti Bio's therapies can precisely kill cancer cells while sparing healthy ones, indicating broad application potential in oncology and other diseases, which may lead to long-term market growth opportunities for the company.
Newsfilter
5.0
2025-12-18Newsfilter
Senti Biosciences Grants New Employee 13,680 Stock Options at $1.31 Each
  • Employee Incentive Program: On December 12, 2025, Senti Bio granted stock options for 13,680 shares to a new employee at an exercise price of $1.31 per share, aimed at attracting and retaining talent, thereby enhancing the company's competitive edge.
  • Plan Background: This grant was made under the Amended and Restated 2022 Inducement Equity Plan adopted on August 5, 2022, in compliance with NASDAQ Listing Rule 5635(c)(4), demonstrating the company's commitment to talent acquisition.
  • Biotechnology Development: Senti Bio focuses on developing next-generation cell and gene therapies using its proprietary Gene Circuit platform, aiming to provide innovative treatment options for patients with incurable diseases, thus positioning the company at the forefront of biotechnology.
  • Market Potential: By engineering Gene Circuits, Senti Bio's therapies have shown potential in preclinical stages for tumor treatment, with future prospects for expansion into other disease areas, further enhancing the company's market value and investment appeal.
NASDAQ.COM
2.0
2025-12-10NASDAQ.COM
Post-Market Surge: Stoke Therapeutics, Alpha Tau Medical, and Compass Pathways Top Biotech Gainers
  • Biotech Stock Movements: Biotech stocks experienced significant fluctuations in after-hours trading, with several companies rebounding after losses during regular trading hours, driven by clinical data, FDA designations, and financing news.

  • Stoke Therapeutics Surge: Stoke Therapeutics saw its stock rise to $33.95 (+11.42%) after presenting positive data on zorevunersen for Dravet syndrome in collaboration with Biogen at a recent conference.

  • Alpha Tau Medical Gains: Alpha Tau Medical's shares surged by 25.26% to $5.30 after announcing the treatment of its first patient in a pilot study for recurrent glioblastoma multiforme using its Alpha DaRT technology.

  • FDA Designation for Senti Biosciences: Senti Biosciences' stock increased to $1.60 (+3.92%) following the FDA granting RMAT designation to its investigational CAR-NK cell therapy for acute myeloid leukemia and other hematologic malignancies.

Wall Street analysts forecast SNTI stock price to rise
3 Analyst Rating
Wall Street analysts forecast SNTI stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
12.00
Averages
12.50
High
13.00
Current: 0.000
sliders
Low
12.00
Averages
12.50
High
13.00
Chardan
Buy
maintain
$12 -> $13
AI Analysis
2025-12-09
Reason
Chardan
Price Target
$12 -> $13
AI Analysis
2025-12-09
maintain
Buy
Reason
Chardan raised the firm's price target on Senti Bio to $13 from $12 and keeps a Buy rating on the shares after the announced updated data from the ongoing Phase I study of SENTI-202 in relapsed/refractory acute myeloid leukemia. The firm believes the days shows "signals of encouraging efficacy and durability" for a broad population. However, Senti's cash runway remains an overhang on the stock, the analyst tells investors in a research note.
Leerink
Jeffrey La Rosa
Outperform
initiated
$6
2025-11-21
Reason
Leerink
Jeffrey La Rosa
Price Target
$6
2025-11-21
initiated
Outperform
Reason
Leerink analyst Jeffrey La Rosa initiated coverage of Senti Bio with an Outperform rating and $6 price target. The firm believes Senti's novel LogicGated gene circuit platform offers a promising solution to solve the therapeutic window problem that has plagued cell therapies pursuing cancers with "dirty" antigen targets. The company's lead clinical candidate, SENTI-202, is an elegantly designed allogeneic, or off-the-shelf, CAR-NK cell therapy in Phase 1 for relapsed or refractory acute myeloid leukemia. For Leerink, the preliminary Phase 1 dose escalation data reported to date help validate SENTI-202's Logic-Gated design and support a potentially differentiated clinical profile relative to currently available AML therapies and the industry's past attempts at developing immune cell-based therapies for the indication.
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Valuation Metrics

The current forward P/E ratio for Senti Biosciences Inc (SNTI.O) is -0.68, compared to its 5-year average forward P/E of -1.11. For a more detailed relative valuation and DCF analysis to assess Senti Biosciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.11
Current PE
-0.68
Overvalued PE
0.29
Undervalued PE
-2.51

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.73
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.98
Undervalued EV/EBITDA
-2.44

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
19.89
Current PS
57.84
Overvalued PS
45.83
Undervalued PS
-6.04

Financials

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Whales Holding SNTI

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New Enterprise Associates, Inc.
Holding
SNTI
-2.25%
3M Return

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Frequently Asked Questions

What is Senti Biosciences Inc (SNTI) stock price today?

The current price of SNTI is 0.9933 USD — it has increased 2.16

What is Senti Biosciences Inc (SNTI)'s business?

Senti Biosciences, Inc. and its subsidiaries is a clinical-stage biotechnology company developing next-generation cell and gene therapies engineered with its gene circuit platform technologies for patients living with incurable diseases. The Company is leveraging its synthetic biology platform to engineer gene circuits into new medicines with enhanced precision and control. These gene circuits are designed to kill cancer cells, to spare healthy cells, to increase specificity to target tissues, and/or to be controllable even after administration. Its product candidates include SENTI-202 and SENTI-301A. SENTI-202 is a potential first-in-class Logic Gated off-the-shelf chimeric antigen receptor natural killer (CAR-NK) investigational cell therapy. SENTI-301A is a multi-armed off-the-shelf healthy donor-derived chimeric antigen receptor natural killer (CAR-NK) cell therapy product candidate designed for the treatment of GPC3 positive tumors.

What is the price predicton of SNTI Stock?

Wall Street analysts forecast SNTI stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SNTI is12.50 USD with a low forecast of 12.00 USD and a high forecast of 13.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Senti Biosciences Inc (SNTI)'s revenue for the last quarter?

Senti Biosciences Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Senti Biosciences Inc (SNTI)'s earnings per share (EPS) for the last quarter?

Senti Biosciences Inc. EPS for the last quarter amounts to -0.69 USD, decreased -89.06

How many employees does Senti Biosciences Inc (SNTI). have?

Senti Biosciences Inc (SNTI) has 34 emplpoyees as of March 11 2026.

What is Senti Biosciences Inc (SNTI) market cap?

Today SNTI has the market capitalization of 26.11M USD.