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MREO Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
0.409
Open
0.389
VWAP
0.40
Vol
821.21K
Mkt Cap
62.32M
Low
0.389
Amount
328.21K
EV/EBITDA(TTM)
--
Total Shares
159.13M
EV
13.62M
EV/OCF(TTM)
--
P/S(TTM)
123.70
Mereo BioPharma Group plc is a biopharmaceutical company focused on the development of therapeutics for rare diseases. The Company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat primarily for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD). In addition to the rare disease programs, it has two oncology product candidates in clinical development, which include Etigilimab, an IgG1 monoclonal antibody which binds to the human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) receptor on immune cells to improve the activation and effectiveness of T-cell and NK cell antitumor activity and Navicixizumab is a bispecific antibody that inhibits delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF). Navicixizumab is developed for the treatment of late-line ovarian cancer.
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Events Timeline

(ET)
2026-01-16
08:50:00
Significant Increases in Borrow Rates for Liquid Options
select
2026-01-12 (ET)
2026-01-12
08:20:00
Mereo BioPharma Updates Cash Runway Guidance to Mid-2027
select
2026-01-08 (ET)
2026-01-08
08:50:00
American Bitcoin Corp Borrow Rate Increases to 8.00%
select
2025-12-30 (ET)
2025-12-30
16:50:00
Major US Indices Close Marginally Lower, Nasdaq Down 0.24%
select
2025-12-30
12:00:00
Major U.S. Averages Mostly Unchanged Near Noon
select

News

Globenewswire
7.0
03-09Globenewswire
Class Action Notice for Mereo BioPharma Investors
  • Class Action Notice: The Portnoy Law Firm advises Mereo BioPharma Group plc investors of a class action for those who purchased securities between June 5, 2023, and December 26, 2025, with a deadline of April 6, 2026, to file a lead plaintiff motion to protect their legal rights.
  • False Statements Allegations: The complaint alleges that defendants provided overly positive statements while concealing significant adverse facts regarding the true status of the Phase 3 ORBIT and COSMIC programs, misleading investors about the company's actual condition.
  • Clinical Trial Failures: On December 29, 2025, Mereo announced that neither the ORBIT nor COSMIC Phase 3 studies achieved statistical significance, failing to meet their primary endpoint of reducing annualized clinical fracture rates compared to placebo or bisphosphonates, despite improvements in bone mineral density.
  • Stock Price Collapse: Following this announcement, Mereo's ADS price plummeted from $2.31 per share on December 26, 2025, to $0.29 per share on December 29, 2025, representing a dramatic decline of over 87.7%, severely impacting investor asset values.
Globenewswire
7.0
03-08Globenewswire
Ultragenyx and Mereo BioPharma Class Action Reminder
  • Lawsuit Initiation: Bragar Eagel & Squire law firm has commenced class actions on behalf of shareholders of Ultragenyx Pharmaceutical (NASDAQ:RARE) and Mereo BioPharma (NASDAQ:MREO), with a lead plaintiff deadline of April 6, 2026, indicating significant investor concern regarding potential risks associated with these companies.
  • Study Result Failures: On December 29, 2025, Ultragenyx announced that its Phase III Orbit and Cosmic studies failed to achieve statistical significance in reducing annualized fracture rates, causing its stock price to plummet by approximately 42.32% in a single day, from $34.19 to $19.72, reflecting market disappointment in the study outcomes.
  • Mereo BioPharma's Reaction: Similarly, Mereo BioPharma announced on December 29, 2025, that its ORBIT and COSMIC studies did not meet the primary endpoint of reducing annualized clinical fracture rates, despite improved bone mineral density, leading to a dramatic decline in its ADS price from $2.31 to $0.29, a drop of over 87.7%, highlighting severe investor confidence erosion.
  • Disclosure Issues: The lawsuits allege that both companies provided overly optimistic projections to investors while concealing significant adverse facts related to the study protocols, resulting in shareholders purchasing stocks at artificially inflated prices, raising concerns about corporate governance and transparency.
Globenewswire
7.0
03-08Globenewswire
Class Action Notice for Mereo BioPharma Investors
  • Class Action Deadline: Investors in Mereo BioPharma Group plc must apply to be lead plaintiffs by April 6, 2026, to potentially receive compensation without any out-of-pocket costs, indicating a significant impact on investor confidence regarding the company's future.
  • False Statements Allegations: The lawsuit alleges that the company misrepresented the expected outcomes of the Phase 3 Orbit and COSMIC studies for setrusumab, leading investors to purchase ADS at inflated prices, highlighting serious deficiencies in the company's transparency and information disclosure practices.
  • Law Firm Credentials: The Rosen Law Firm specializes in securities class actions and has recovered over $438 million for investors in 2019 alone, showcasing its proven track record and expertise in handling similar cases, which enhances investor trust in their representation.
  • Investor Guidance: The law firm advises investors to select qualified counsel with a successful track record to avoid partnering with inexperienced intermediaries, ensuring they receive the best legal support and potential compensation in the class action.
Globenewswire
7.0
03-06Globenewswire
Class Action Filed Against Mereo BioPharma Group for Securities Violations
  • Class Action Initiated: Bronstein, Gewirtz & Grossman LLC has filed a class action lawsuit against Mereo BioPharma Group, seeking damages for investors who purchased securities between June 5, 2023, and December 26, 2025, reflecting strong investor response to potential fraud allegations.
  • Allegations of False Statements: The complaint alleges that Mereo provided overly positive statements to investors while concealing significant adverse facts regarding the Phase 3 ORBIT and COSMIC programs, which failed to meet their primary endpoints, potentially undermining investor confidence.
  • Call to Action for Investors: Affected investors are encouraged to apply to be lead plaintiffs by April 6, 2026, to share in any potential recovery from the lawsuit, indicating the legal team's commitment to protecting investor rights.
  • No-Cost Legal Services: The law firm offers legal representation on a contingency fee basis, meaning they will only charge fees if they successfully recover funds, thereby reducing the legal risk for investors and enhancing the appeal of participating in the lawsuit.
Globenewswire
7.0
03-06Globenewswire
Mereo BioPharma Faces Class Action Lawsuit
  • Class Action Reminder: The Schall Law Firm alerts investors of a class action lawsuit against Mereo BioPharma Group plc for violations of §§10(b) and 20(a) of the Securities Exchange Act, concerning securities purchased between June 5, 2023, and December 26, 2025.
  • False Statements Exposed: The complaint alleges that Mereo concealed negative facts about its Phase 3 ORBIT and COSMIC programs, rendering its public statements false and materially misleading throughout the class period.
  • Investor Losses: When the market learned that Mereo failed to meet its primary endpoints, investors suffered damages, indicating significant deficiencies in the company's disclosure practices that could impact future stock performance.
  • Legal Consultation Opportunity: The Schall Law Firm encourages affected investors to contact them before April 6, 2026, to participate in the lawsuit and discuss their rights, demonstrating a commitment to protecting investor interests.
PRnewswire
7.0
03-06PRnewswire
Faruqi & Faruqi Encourages Mereo Investors to Reach Out
  • Legal Investigation Launched: Faruq & Faruqi, LLP is investigating potential claims against Mereo BioPharma, specifically targeting investors who purchased or acquired securities between June 5, 2023, and December 26, 2025, to protect their legal rights.
  • Class Action Reminder: The firm reminds investors of the April 6, 2026 deadline to seek the role of lead plaintiff in a federal securities class action filed against Mereo, urging timely action to safeguard their interests.
  • Direct Contact Channels: Investors who suffered losses are encouraged to reach out directly to Faruqi & Faruqi's Securities Litigation Partner Josh Wilson at 877-247-4292 or 212-983-9330 (Ext. 1310) for consultation.
  • Investor Rights Protection: This legal action aims to support affected investors and ensure they receive due compensation in potential securities fraud cases, reflecting the firm's commitment to protecting investor rights.
Wall Street analysts forecast MREO stock price to rise
8 Analyst Rating
Wall Street analysts forecast MREO stock price to rise
6 Buy
2 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
0.50
Averages
2.08
High
5.00
Current: 0.000
sliders
Low
0.50
Averages
2.08
High
5.00
Cantor Fitzgerald
Kristen Kluska
Overweight
downgrade
$6 -> $3
AI Analysis
2025-12-29
Reason
Cantor Fitzgerald
Kristen Kluska
Price Target
$6 -> $3
AI Analysis
2025-12-29
downgrade
Overweight
Reason
Cantor Fitzgerald analyst Kristen Kluska lowered the firm's price target on Mereo BioPharma to $3 from $6 and keeps an Overweight rating on the shares after the company announced that neither of the Phase 3 Orbit and Cosmic studies for setrusumab in Osteogenesis Imperfecta achieved statistical significance against their primary endpoints.
LifeSci Capital
Outperform -> Market Perform
downgrade
2025-12-29
Reason
LifeSci Capital
Price Target
2025-12-29
downgrade
Outperform -> Market Perform
Reason
LifeSci Capital downgraded Mereo BioPharma to Market Perform from Outperform.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MREO
Unlock Now

Valuation Metrics

The current forward P/E ratio for Mereo BioPharma Group PLC (MREO.O) is -15.80, compared to its 5-year average forward P/E of -80.12. For a more detailed relative valuation and DCF analysis to assess Mereo BioPharma Group PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-80.12
Current PE
-15.80
Overvalued PE
21.45
Undervalued PE
-181.69

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.75
Current EV/EBITDA
0.90
Overvalued EV/EBITDA
5.48
Undervalued EV/EBITDA
-6.97

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
9.86
Current PS
4.64
Overvalued PS
19.49
Undervalued PS
0.24

Financials

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Whales Holding MREO

E
EcoR1 Capital, LLC
Holding
MREO
+4.63%
3M Return

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Frequently Asked Questions

What is Mereo BioPharma Group PLC (MREO) stock price today?

The current price of MREO is 0.3997 USD — it has increased 2.04

What is Mereo BioPharma Group PLC (MREO)'s business?

Mereo BioPharma Group plc is a biopharmaceutical company focused on the development of therapeutics for rare diseases. The Company has developed a portfolio of late-stage clinical product candidates, and its two rare disease product candidates are setrusumab for the treatment of osteogenesis imperfecta (OI) and alvelestat primarily for the treatment of severe alpha-1 antitrypsin deficiency-associated lung disease (AATD-LD). In addition to the rare disease programs, it has two oncology product candidates in clinical development, which include Etigilimab, an IgG1 monoclonal antibody which binds to the human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) receptor on immune cells to improve the activation and effectiveness of T-cell and NK cell antitumor activity and Navicixizumab is a bispecific antibody that inhibits delta-like ligand 4 (DLL4) and vascular endothelial growth factor (VEGF). Navicixizumab is developed for the treatment of late-line ovarian cancer.

What is the price predicton of MREO Stock?

Wall Street analysts forecast MREO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MREO is2.08 USD with a low forecast of 0.50 USD and a high forecast of 5.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Mereo BioPharma Group PLC (MREO)'s revenue for the last quarter?

Mereo BioPharma Group PLC revenue for the last quarter amounts to 0.00 USD, decreased

What is Mereo BioPharma Group PLC (MREO)'s earnings per share (EPS) for the last quarter?

Mereo BioPharma Group PLC. EPS for the last quarter amounts to -0.01 USD, decreased -50.00

How many employees does Mereo BioPharma Group PLC (MREO). have?

Mereo BioPharma Group PLC (MREO) has 36 emplpoyees as of March 10 2026.

What is Mereo BioPharma Group PLC (MREO) market cap?

Today MREO has the market capitalization of 62.32M USD.