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ATOS Overview

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0.000
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ET
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Intellectia

Loading chart...

High
5.260
Open
4.770
VWAP
5.10
Vol
42.72K
Mkt Cap
45.30M
Low
4.770
Amount
217.71K
EV/EBITDA(TTM)
--
Total Shares
8.61M
EV
-739.49K
EV/OCF(TTM)
--
P/S(TTM)
--
Atossa Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is engaged in developing medicines in areas of unmet medical need in oncology with a focus on women’s breast cancer and other breast conditions. Its lead drug candidate under development is oral (Z)-endoxifen, which it is developing for both the prevention and treatment of breast cancer. (Z)-endoxifen is the potent Selective Estrogen Receptor Modulator for estrogen receptor inhibition and causes estrogen receptor degradation. In addition to its potent anti-estrogen effects, (Z)-endoxifen has been shown to target PKCB1, a known oncogenic protein, at clinically attainable blood concentrations. It is developing a form of (Z)-endoxifen which is administered orally for the potential treatment of breast cancer and reduction of breast density. It has completed four Phase I clinical studies and two Phase II clinical studies with its proprietary (Z)-endoxifen (including oral and topical formulations).
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Events Timeline

(ET)
2026-03-25
17:40:00
CEO Quay: 2024 EPS at -$3.04
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2026-03-19 (ET)
2026-03-19
08:10:00
Atossa Therapeutics Appoints New Medical Directors
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2026-01-30 (ET)
2026-01-30
20:00:00
Atossa Genetics Trading Halted, News Pending
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2026-01-16 (ET)
2026-01-16
16:50:00
Atossa Therapeutics Receives FDA Orphan Drug Designation for (Z)-endoxifen
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2026-01-15 (ET)
2026-01-15
21:40:00
Atossa Therapeutics' (Z)-endoxifen Granted FDA Orphan Designation
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link
2026-01-06 (ET)
2026-01-06
08:20:00
Atossa Therapeutics Receives FDA Approval to Proceed with Breast Cancer Study
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2025-12-15 (ET)
2025-12-15
08:10:00
Atossa Therapeutics Updates (Z)-Endoxifen Clinical Trials at SABCS
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2025-12-11 (ET)
2025-12-11
08:10:00
Atossa Therapeutics Receives FDA Rare Pediatric Disease Designation for (Z)-Endoxifen
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News

seekingalpha
9.5
03-26seekingalpha
Atossa Therapeutics Reports FY Losses
  • Disappointing Earnings: Atossa Therapeutics reported a FY GAAP EPS of -$4.04, missing expectations by $0.22, indicating ongoing challenges in profitability that could undermine investor confidence.
  • Negative Market Reaction: The failure to meet earnings expectations may put pressure on Atossa's stock price, prompting investors to monitor subsequent market dynamics and the company's strategic responses.
  • Historical Financial Data: Historical financial data indicates persistent underperformance in Atossa's profitability, reflecting high costs in R&D and marketing, which may lead to increased future financing needs.
  • Quantitative Rating Analysis: Seeking Alpha's quantitative rating on Atossa Therapeutics reveals a cautious market outlook regarding its future performance, necessitating close attention to the company's strategic adjustments and market reactions.
stocktwits
9.5
03-25stocktwits
ATOS Shares Decline Post-Market Following Earnings Disappointment — CEO Focuses on Innovative Applications for Experimental Cancer Treatment
  • Company Financial Performance: Atossa Therapeutics reported a net loss per share of $4.04 for 2025, an increase from a loss of $3.04 in 2024, alongside rising operating expenses due to research and development costs.

  • FDA Designations: The company received Rare Pediatric Disease designation for its investigational therapy for Duchenne Muscular Dystrophy (DMD) in December and Orphan Drug designation in January, which are expected to expedite FDA review processes.

  • Stock Market Reaction: Following the financial report, Atossa's stock dropped 4% after hours, reflecting ongoing investor concerns, with the stock having fallen 50% over the past year.

  • Future Focus: Atossa plans to prioritize resources towards oncology and rare disease areas with higher potential returns, while it will not advance its drug for metastatic breast cancer due to cost and timeline constraints.

PRnewswire
9.5
03-25PRnewswire
Atossa Therapeutics Reports 2025 Financial Results and Updates
  • Financial Overview: Atossa Therapeutics reported total operating expenses of $37.1 million for 2025, an increase of 34.5% from $27.6 million in 2024, indicating rising expenditures in R&D and management that could impact future profitability.
  • R&D Spending Surge: Research and development expenses reached $21.2 million in 2025, up 50% from $14.1 million in 2024, with clinical and non-clinical trial costs increasing by 60%, reflecting the company's ongoing commitment to oncology and new drug development.
  • Widening Net Loss: The net loss for 2025 was $34.8 million, a 36.3% increase from $25.5 million in 2024, suggesting greater financial pressure as the company advances its product candidates, which may affect investor confidence.
  • FDA Designation Progress: Atossa's (Z)-endoxifen received FDA Rare Pediatric Disease and Orphan Drug designations, which not only expedite the FDA review process but also provide potential financial benefits for future development, enhancing the company's competitive position in the market.
Newsfilter
9.5
03-25Newsfilter
Atossa Therapeutics Reports 2025 Financial Results and Corporate Developments
  • Financial Performance: Atossa reported total operating expenses of $37.1 million for 2025, a 34% increase from $27.6 million in 2024, primarily driven by rising R&D costs, indicating ongoing investment in clinical trials.
  • R&D Progress: The FDA granted Rare Pediatric Disease designation for Atossa's (Z)-endoxifen for Duchenne Muscular Dystrophy (DMD), highlighting its potential in treating serious conditions and the possibility of obtaining a Priority Review Voucher, enhancing market competitiveness.
  • Management Team Strengthening: Atossa appointed two experienced biopharma executives as Medical Directors for Breast Oncology and Rare Diseases, aiming to bolster the company's execution capabilities in breast cancer and rare disease programs, facilitating progress toward clinical and regulatory milestones.
  • Industry Recognition: Atossa received the Research and Development Excellence Award in the Precision Endocrine Therapy category at the 2025 Clinical Trials Arena Excellence Awards, underscoring its innovative efforts in advancing (Z)-endoxifen and enhancing its reputation in the biopharmaceutical sector.
moomoo
9.5
03-25moomoo
ATOSSA THERAPEUTICS ANNOUNCES 2025 FOURTH QUARTER AND YEAR-END FINANCIAL RESULTS ALONG WITH A CORPORATE UPDATE
  • Financial Results: ATO Therapeutics reports its financial results for the fourth quarter and year-end 2025, highlighting key performance metrics and financial health.

  • Corporate Update: The report provides a comprehensive corporate update, detailing recent developments and strategic initiatives undertaken by the company.

Globenewswire
8.5
03-19Globenewswire
Biotech Investment Revives as Institutional Capital Flows Back
  • Capital Flow Trend: In early 2026, institutional investors significantly increased financing activities in the biotech sector, indicating a strong interest in clinical-stage companies with validated science, which is expected to drive industry recovery and attract more investments.
  • Precision Medicine Market Outlook: The global oncology precision medicine market is projected to reach $303 billion by 2035, growing at approximately 9% annually, providing substantial market opportunities for companies focused on precision medicine, particularly in cancer treatment.
  • Oncolytics Biotech New Data: Oncolytics Biotech is set to present new mechanistic and translational data for its drug pelareorep at the upcoming AACR Annual Meeting, with preliminary results indicating that the drug may enhance tumor sensitivity to immunotherapy, potentially altering treatment strategies.
  • OS Therapies Accelerated Approval Progress: OS Therapies' OST-HER2 immunotherapy has received an elevation to a Type B meeting with the FDA, signaling a transition to accelerated approval discussions following the submission of its clinical data package, which could provide a significant competitive advantage in the market.
Wall Street analysts forecast ATOS stock price to rise
4 Analyst Rating
Wall Street analysts forecast ATOS stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
7.00
Averages
18.33
High
40.00
Current: 0.000
sliders
Low
7.00
Averages
18.33
High
40.00
H.C. Wainwright
NULL -> Buy
maintain
$7 -> $25
AI Analysis
2026-03-26
Reason
H.C. Wainwright
Price Target
$7 -> $25
AI Analysis
2026-03-26
maintain
NULL -> Buy
Reason
H.C. Wainwright adjusted the firm's price target on Atossa Therapeutics to $25 from $7 and keeps a Buy rating on the shares. The firm cites the company's 1-for-15 reverse stock split for the change.
Craig-Hallum
Craig-Hallum
Buy
downgrade
$35 -> $10
2026-02-12
Reason
Craig-Hallum
Craig-Hallum
Price Target
$35 -> $10
2026-02-12
downgrade
Buy
Reason
Craig-Hallum lowered the firm's price target on Atossa Therapeutics to $10 from $35 and keeps a Buy rating on the shares. The firm cites Atossa's decision to pause Z-endoxifen's development in metastatic breast cancer to prioritize other breast cancer settings and DMD. Z-endoxifen's other breast cancer studies remain ongoing including the I-SPY and EVANGELINE studies in neoadjuvant breast cancer, where data updates are expected later this year. The year-end 2025 cash balance of about $40M provides at least one year of runway, argues Craig-Hallum.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ATOS
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Valuation Metrics

The current forward P/E ratio for Atossa Therapeutics Inc (ATOS.O) is 0.00, compared to its 5-year average forward P/E of -6.20. For a more detailed relative valuation and DCF analysis to assess Atossa Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-6.20
Current PE
0.00
Overvalued PE
0.06
Undervalued PE
-12.45

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

AI Analysis
Annual
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Frequently Asked Questions

What is Atossa Therapeutics Inc (ATOS) stock price today?

The current price of ATOS is 5.26 USD — it has increased 11.68

What is Atossa Therapeutics Inc (ATOS)'s business?

Atossa Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is engaged in developing medicines in areas of unmet medical need in oncology with a focus on women’s breast cancer and other breast conditions. Its lead drug candidate under development is oral (Z)-endoxifen, which it is developing for both the prevention and treatment of breast cancer. (Z)-endoxifen is the potent Selective Estrogen Receptor Modulator for estrogen receptor inhibition and causes estrogen receptor degradation. In addition to its potent anti-estrogen effects, (Z)-endoxifen has been shown to target PKCB1, a known oncogenic protein, at clinically attainable blood concentrations. It is developing a form of (Z)-endoxifen which is administered orally for the potential treatment of breast cancer and reduction of breast density. It has completed four Phase I clinical studies and two Phase II clinical studies with its proprietary (Z)-endoxifen (including oral and topical formulations).

What is the price predicton of ATOS Stock?

Wall Street analysts forecast ATOS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ATOS is18.33 USD with a low forecast of 7.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Atossa Therapeutics Inc (ATOS)'s revenue for the last quarter?

Atossa Therapeutics Inc revenue for the last quarter amounts to -11.44M USD, increased 59.92

What is Atossa Therapeutics Inc (ATOS)'s earnings per share (EPS) for the last quarter?

Atossa Therapeutics Inc. EPS for the last quarter amounts to -10546000.00 USD, increased 49.57

How many employees does Atossa Therapeutics Inc (ATOS). have?

Atossa Therapeutics Inc (ATOS) has 14 emplpoyees as of April 01 2026.

What is Atossa Therapeutics Inc (ATOS) market cap?

Today ATOS has the market capitalization of 45.30M USD.