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ATOS Overview

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0.000(0.000%)Aft-market
ET
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0.000
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ET
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Intellectia

Loading chart...

High
5.660
Open
5.550
VWAP
5.55
Vol
30.93K
Mkt Cap
48.22M
Low
5.500
Amount
171.76K
EV/EBITDA(TTM)
--
Total Shares
8.61M
EV
16.51M
EV/OCF(TTM)
--
P/S(TTM)
--
Atossa Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is engaged in developing medicines in areas of unmet medical need in oncology with a focus on women’s breast cancer and other breast conditions. Its lead drug candidate under development is oral (Z)-endoxifen, which it is developing for both the prevention and treatment of breast cancer. (Z)-endoxifen is the potent Selective Estrogen Receptor Modulator for estrogen receptor inhibition and causes estrogen receptor degradation. In addition to its potent anti-estrogen effects, (Z)-endoxifen has been shown to target PKCB1, a known oncogenic protein, at clinically attainable blood concentrations. It is developing a form of (Z)-endoxifen which is administered orally for the potential treatment of breast cancer and reduction of breast density. It has completed four Phase I clinical studies and two Phase II clinical studies with its proprietary (Z)-endoxifen (including oral and topical formulations).
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Events Timeline

(ET)
2026-05-08
08:50:00
Atossa Therapeutics Advances (Z)-endoxifen Development Strategy
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2026-05-06 (ET)
2026-05-06
08:40:00
Atossa Therapeutics Publishes KARISMA Endoxifen Trial Results
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2026-05-04 (ET)
2026-05-04
08:40:00
Atossa Therapeutics Receives FDA Rare Pediatric Disease Designation
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2026-03-25 (ET)
2026-03-25
17:40:00
CEO Quay: 2024 EPS at -$3.04
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2026-03-19 (ET)
2026-03-19
08:10:00
Atossa Therapeutics Appoints New Medical Directors
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2026-01-30 (ET)
2026-01-30
20:00:00
Atossa Genetics Trading Halted, News Pending
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2026-01-16 (ET)
2026-01-16
16:50:00
Atossa Therapeutics Receives FDA Orphan Drug Designation for (Z)-endoxifen
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2026-01-15 (ET)
2026-01-15
21:40:00
Atossa Therapeutics' (Z)-endoxifen Granted FDA Orphan Designation
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link

News

seekingalpha
9.5
05-08seekingalpha
Atossa Therapeutics Q1 Financial Results
  • Loss per Share: Atossa Therapeutics reported a GAAP EPS of -$1.11 for Q1 2026, indicating ongoing challenges in profitability that could undermine investor confidence.
  • Increased Operating Expenses: The total operating expenses for the three months ended March 31, 2026, reached $9.9 million, up $2.5 million from $7.4 million in the same period of 2025, reflecting rising costs that may impact future financial flexibility.
  • Reasons for Expense Growth: The increase in operating expenses is primarily attributed to higher spending on research and marketing, suggesting that Atossa is preparing for future product launches and market expansion, but may exert pressure on cash flow in the short term.
  • Financial Health Risks: The ongoing losses and rising operating expenses could lead to greater pressure on Atossa regarding financing and investor trust, potentially affecting its long-term strategic development and market competitiveness.
PRnewswire
9.5
05-08PRnewswire
Atossa Therapeutics Reports Q1 2026 Financial Results and Updates
  • Significant R&D Progress: Atossa Therapeutics advanced its (Z)-endoxifen clinical development in Q1 2026, particularly for breast cancer and rare diseases like Duchenne Muscular Dystrophy and McCune-Albright Syndrome, securing FDA Orphan Drug and Rare Pediatric Disease designations, highlighting its potential in high unmet medical needs.
  • Increased Operating Expenses: Total operating expenses for Q1 2026 reached $9.9 million, up $2.5 million from $7.4 million in Q1 2025, primarily driven by rising R&D and administrative costs, reflecting the company's ongoing investment in product development.
  • R&D Expense Breakdown: Within R&D expenses, clinical and pre-clinical trial costs amounted to $3.718 million, a 35% increase from the previous year, indicating a significant commitment to new drug development, although overall R&D expenses also experienced fluctuations in other areas.
  • Strong Financial Position: As of March 31, 2026, Atossa reported cash and cash equivalents of $31.718 million, a decrease from $41.299 million at the end of 2025, yet the company maintains a solid financial foundation to support future strategic plans and enhance shareholder value.
PRnewswire
9.0
05-06PRnewswire
Atossa Announces KARISMA Trial Results for Endoxifen in Breast Cancer Prevention
  • Clinical Trial Results: Atossa Therapeutics published results from the KARISMA Endoxifen trial in the Journal of the National Cancer Institute, demonstrating that low-dose Endoxifen significantly reduced mammographic density (MBD), a key risk factor for breast cancer, with a 19.3% reduction at 1 mg and 26.5% at 2 mg, providing a new therapeutic option for future breast cancer risk reduction.
  • Safety and Tolerability: The trial showed that the 1 mg dose of Endoxifen had a similar tolerability profile to placebo, with only 5 adverse events in the 1 mg group compared to 11 in the 2 mg group, indicating the potential for long-term use of low-dose Endoxifen and improved patient acceptance.
  • Dose Selection Insights: The study revealed that significant MBD reduction occurred at plasma concentrations of 3-4 ng/mL, with more prominent adverse effects at higher concentrations, providing crucial insights for future prevention studies and supporting the 1 mg dose as the preferred candidate.
  • Strategic Implications: Atossa believes these results strengthen the rationale for advancing Endoxifen as a potential MBD reduction therapy, particularly for women with elevated MBD who may be hesitant to use current options, signaling new opportunities in the breast cancer prevention landscape.
Newsfilter
9.0
05-06Newsfilter
Atossa Reports Positive Results from Endoxifen Clinical Trial for Breast Cancer Risk Reduction
  • Clinical Trial Results: Atossa Therapeutics' KARISMA Endoxifen trial demonstrated that both 1 mg and 2 mg doses significantly reduced mammographic breast density over six months, with reductions of 19.3% and 26.5% respectively, providing strong support for future breast cancer risk reduction strategies.
  • Safety and Tolerability: The 1 mg Endoxifen dose exhibited a tolerability profile similar to placebo, with low adverse event rates, indicating its potential value in breast cancer prevention, particularly for women hesitant about existing treatment options.
  • Dose Selection Insights: The study revealed that meaningful reductions in breast density occurred at low Endoxifen plasma concentrations of 3-4 ng/mL, while higher concentrations were associated with increased vasomotor symptoms, supporting the 1 mg dose as the preferred candidate for future studies.
  • Strategic Implications: Atossa believes these results strengthen the rationale for advancing Endoxifen as a potential therapy for reducing mammographic density, particularly for women with elevated density or other risk factors, potentially transforming current breast cancer prevention paradigms.
stocktwits
8.5
05-04stocktwits
Atossa's Drug Receives Rare Pediatric Disease Designation
  • FDA Designation Progress: Atossa Therapeutics' (Z)-endoxifen has received Rare Pediatric Disease (RPD) designation from the FDA for treating McCune-Albright Syndrome in females, marking a significant advancement in addressing pediatric rare diseases.
  • Positive Market Reaction: Following this announcement, Atossa's stock surged over 8%, reflecting investor confidence in the company's ability to meet serious medical needs, despite the stock's decline of more than 40% year-to-date.
  • Potential Economic Value: Should (Z)-endoxifen gain approval through a New Drug Application (NDA) or Biologics License Application (BLA), it may qualify for a Priority Review Voucher (PRV), with reported PRV sales ranging from $100 million to $205 million over the past 18 to 24 months, indicating substantial economic potential.
  • CEO Outlook: CEO Steven Quay stated that (Z)-endoxifen could improve outcomes for patients with McCune-Albright Syndrome while creating non-dilutive value through the RPD program, underscoring the company's strategic focus on rare diseases.
PRnewswire
8.5
05-04PRnewswire
Atossa Secures Rare Pediatric Disease Designation for (Z)-endoxifen
  • Rare Disease Certification: Atossa Therapeutics' (Z)-endoxifen has received FDA's Rare Pediatric Disease (RPD) designation for treating McCune-Albright Syndrome in females, marking a significant milestone in the company's development of new therapies and is expected to enhance its market competitiveness.
  • Priority Review Voucher Potential: Upon approval, (Z)-endoxifen will be eligible for a Priority Review Voucher (PRV), which has seen sales ranging from $100 million to $205 million in the past 18-24 months, potentially providing non-dilutive value to the company.
  • Clinical Need Fulfillment: McCune-Albright Syndrome is a serious pediatric endocrine disorder that particularly affects young girls, and (Z)-endoxifen has the potential to improve treatment outcomes for patients, addressing the urgent demand for effective therapeutic options in the market.
  • Enhanced R&D Collaboration: Atossa's participation in the FD/MAS Alliance Research Priorities Workshop underscores its commitment to collaborating with the clinical and patient community, aiming to accelerate the development of new therapies and further advance the clinical progress of (Z)-endoxifen.
Wall Street analysts forecast ATOS stock price to rise
4 Analyst Rating
Wall Street analysts forecast ATOS stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
7.00
Averages
18.33
High
40.00
Current: 0.000
sliders
Low
7.00
Averages
18.33
High
40.00
H.C. Wainwright
NULL -> Buy
maintain
$7 -> $25
AI Analysis
2026-03-26
Reason
H.C. Wainwright
Price Target
$7 -> $25
AI Analysis
2026-03-26
maintain
NULL -> Buy
Reason
H.C. Wainwright adjusted the firm's price target on Atossa Therapeutics to $25 from $7 and keeps a Buy rating on the shares. The firm cites the company's 1-for-15 reverse stock split for the change.
Craig-Hallum
Craig-Hallum
Buy
downgrade
$35 -> $10
2026-02-12
Reason
Craig-Hallum
Craig-Hallum
Price Target
$35 -> $10
2026-02-12
downgrade
Buy
Reason
Craig-Hallum lowered the firm's price target on Atossa Therapeutics to $10 from $35 and keeps a Buy rating on the shares. The firm cites Atossa's decision to pause Z-endoxifen's development in metastatic breast cancer to prioritize other breast cancer settings and DMD. Z-endoxifen's other breast cancer studies remain ongoing including the I-SPY and EVANGELINE studies in neoadjuvant breast cancer, where data updates are expected later this year. The year-end 2025 cash balance of about $40M provides at least one year of runway, argues Craig-Hallum.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ATOS
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Valuation Metrics

The current forward P/E ratio for Atossa Therapeutics Inc (ATOS.O) is 7.04, compared to its 5-year average forward P/E of -5.75. For a more detailed relative valuation and DCF analysis to assess Atossa Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.75
Current PE
7.04
Overvalued PE
0.64
Undervalued PE
-12.14

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

Financials

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Frequently Asked Questions

What is Atossa Therapeutics Inc (ATOS) stock price today?

The current price of ATOS is 5.5 USD — it has decreased -1.79

What is Atossa Therapeutics Inc (ATOS)'s business?

Atossa Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is engaged in developing medicines in areas of unmet medical need in oncology with a focus on women’s breast cancer and other breast conditions. Its lead drug candidate under development is oral (Z)-endoxifen, which it is developing for both the prevention and treatment of breast cancer. (Z)-endoxifen is the potent Selective Estrogen Receptor Modulator for estrogen receptor inhibition and causes estrogen receptor degradation. In addition to its potent anti-estrogen effects, (Z)-endoxifen has been shown to target PKCB1, a known oncogenic protein, at clinically attainable blood concentrations. It is developing a form of (Z)-endoxifen which is administered orally for the potential treatment of breast cancer and reduction of breast density. It has completed four Phase I clinical studies and two Phase II clinical studies with its proprietary (Z)-endoxifen (including oral and topical formulations).

What is the price predicton of ATOS Stock?

Wall Street analysts forecast ATOS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ATOS is18.33 USD with a low forecast of 7.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Atossa Therapeutics Inc (ATOS)'s revenue for the last quarter?

Atossa Therapeutics Inc revenue for the last quarter amounts to -9.87M USD, increased 33.13

What is Atossa Therapeutics Inc (ATOS)'s earnings per share (EPS) for the last quarter?

Atossa Therapeutics Inc. EPS for the last quarter amounts to -9581000.00 USD, increased 60.54

How many employees does Atossa Therapeutics Inc (ATOS). have?

Atossa Therapeutics Inc (ATOS) has 14 emplpoyees as of May 11 2026.

What is Atossa Therapeutics Inc (ATOS) market cap?

Today ATOS has the market capitalization of 48.22M USD.