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PSTV Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
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ET
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Intellectia

Loading chart...

High
6.400
Open
6.380
VWAP
6.01
Vol
191.51K
Mkt Cap
45.70M
Low
5.800
Amount
1.15M
EV/EBITDA(TTM)
--
Total Shares
6.88M
EV
25.61M
EV/OCF(TTM)
--
P/S(TTM)
5.18
Plus Therapeutics, Inc. is a clinical-stage pharmaceutical company. The Company is engaged in developing targeted radiotherapeutics for difficult-to-treat cancers of the central nervous system. Combining image-guided local beta radiation and targeted drug delivery approaches, it is advancing a pipeline of product candidates with lead programs in leptomeningeal metastases (LM) and recurrent glioblastoma (GBM). Its lead radiotherapeutic candidate, REYOBIQ (rhenium (186Re) obisbemeda), is designed specifically for CNS cancers including GBM, LM, and pediatric brain cancers (PBC) by direct localized delivery utilizing approved standard-of-care tissue access such as with convection-enhanced delivery (CED) and intraventricular brain (Ommaya reservoir) catheters. Its radiotherapeutic candidate, Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere (188RNL-BAM), is designed to treat many solid organ cancers including primary and secondary liver cancers via intra-arterial injections.
Show More

Events Timeline

(ET)
2026-05-19
07:40:00
Plus Therapeutics Signs Strategic Partnership with Ephemeral Technologies
select
2026-05-15 (ET)
2026-05-15
16:10:00
Plus Therapeutics Q1 Revenue Exceeds Expectations at $1.03M
select
2026-04-09 (ET)
2026-04-09
07:40:00
Plus Therapeutics Appoints Eric Daniels as Chief Development Officer
select
2026-04-08 (ET)
2026-04-08
07:40:00
Plus Therapeutics Receives Orphan Drug Designation for Reyobiq in Pediatric Malignant Gliomas
select
2026-04-07 (ET)
2026-04-07
07:40:00
Plus Therapeutics Receives AMA Approval for New Billing Code
select
2026-04-06 (ET)
2026-04-06
18:20:00
Plus Therapeutics' Cancer Treatment Receives FDA Orphan Designation
select
link

News

Newsfilter
8.5
05-26Newsfilter
CNSide Enables Early Diagnosis, Reducing Healthcare Costs by 40%
  • Cost Reduction in Healthcare: The study indicates that CNSide's early diagnosis and therapeutic management can reduce LM-related healthcare costs by approximately 40%, driven by earlier interventions and improved treatment precision, thereby alleviating the financial burden on patients.
  • Blue Ribbon Recognition: The poster presented at the ISPOR Annual Meeting received Blue Ribbon recognition for its significant contributions to health economics and outcomes research, highlighting the global importance of the findings and enhancing the company's reputation in the industry.
  • Clinical Decision Support: CNSide's detection capabilities provide clinicians with actionable information earlier in the disease course, which not only improves patient quality of life but also optimizes the efficiency of healthcare resource allocation.
  • Market Validation: The payer agreements established by the company validate the economic benefits of CNSide, indicating a successful commercialization process in the U.S. market, with potential for further market share expansion and profitability enhancement.
Newsfilter
7.5
05-19Newsfilter
Plus Therapeutics Partners with Ephemeral to Develop AI-Driven CNS Oncology Platform
  • Strategic Partnership: Plus Therapeutics has signed a strategic partnership agreement with Ephemeral Technologies to develop a unique AI execution platform aimed at integrating and analyzing therapeutic, diagnostic, and bioinformatics datasets in CNS oncology, thereby accelerating the advancement of precision neuro-oncology.
  • Data Integration and Intelligence: The platform will combine Plus's multi-modal, longitudinal data with generative AI reasoning and agentic workflows, expected to create both near- and long-term value for shareholders while enhancing laboratory and clinical operational efficiency.
  • Industry Leadership: Plus CEO Marc Hedrick stated that this collaboration will further solidify Plus's leadership position in CNS oncology, focusing on improving survival rates for patients facing the most challenging cancers.
  • Future Development Outlook: Plus plans to increasingly adopt AI technologies post-2026 to fully integrate operational workflows, support clinical decision-making, patient stratification, and precision oncology initiatives, while fostering collaborations with pharmaceutical companies and collecting real-world evidence.
seekingalpha
9.5
05-15seekingalpha
Plus Therapeutics Q1 Earnings Report Analysis
  • Earnings Performance: Plus Therapeutics reported a Q1 GAAP EPS of -$1.05, missing expectations by $0.15, indicating ongoing challenges in profitability that could affect investor confidence.
  • Revenue Situation: The company reported grant revenue of $1.03M, down 2.8% year-over-year, although it beat expectations by $0.06M; however, the revenue decline may reflect weak market demand, necessitating attention to future growth potential.
  • Cash Flow Status: As of March 31, 2026, Plus Therapeutics had a cash and investments balance of $15.1M, significantly up from $8.6M as of December 31, 2025, indicating improved financial management that supports future R&D activities.
  • Compliance Restoration: The company has regained compliance with Nasdaq and announced a 1-for-25 reverse stock split, a move that may help stabilize the stock price and enhance market confidence in the company.
Newsfilter
9.0
05-08Newsfilter
Plus Therapeutics Presents REYOBIQ Clinical Data at AANS Annual Meeting
  • Clinical Data Highlights: At the 2026 AANS Annual Meeting, Plus Therapeutics presented data from the Phase 1 ReSPECT-LM trial of REYOBIQ, showing a median overall survival of approximately 9 months at the recommended Phase 2 dose, significantly better than the historical range of 2-6 months, indicating the therapy's potential for patients with leptomeningeal metastases lacking FDA-approved treatments.
  • Anti-Tumor Activity: The study demonstrated robust anti-tumor activity, including significant reductions in circulating tumor cells (CTC) and clinical benefits, supporting the advancement of REYOBIQ into later-stage clinical development and potentially offering new treatment options for patients.
  • Safety and Tolerability: REYOBIQ exhibited a favorable safety and tolerability profile, which supports its progression into later-stage clinical trials, with a target-to-off-target absorbed dose ratio exceeding 100:1, minimizing exposure to healthy tissue.
  • Immune Remodeling Potential: Translational analyses indicated that REYOBIQ may induce immune remodeling within the tumor microenvironment, including activation of CD8+ T cells and enhancement of anti-tumor immune responses, supporting potential future combination strategies with immunotherapies.
Newsfilter
8.5
05-07Newsfilter
Plus Therapeutics Secures Medicare Enrollment for CNSide Diagnostics
  • Successful Medicare Enrollment: Plus Therapeutics' wholly owned subsidiary, CNSide Diagnostics, has successfully enrolled in Medicare and received a Provider Transaction Access Number (PTAN), marking a critical step in its commercialization strategy for the CNSide® Cerebrospinal Fluid assay platform, which is expected to significantly enhance the company's revenue potential in the U.S. market.
  • Expanded Coverage: The Medicare enrollment allows CNSide Diagnostics to serve approximately half of the U.S. Medicare population, which not only improves patient access to testing but also paves the way for future entry into Medicare Advantage plans, thereby strengthening the company's competitive position in the market.
  • Accelerated Pricing and Coverage Efforts: With enrollment secured, CNSide Diagnostics will actively engage with local Medicare Administrative Contractors (MACs) to pursue local coverage determinations (LCDs) and support pricing decisions under the Clinical Laboratory Fee Schedule (CLFS), optimizing revenue capture.
  • Commercial Expansion Plans: The company aims to further broaden its coverage through national and regional payer contracts, targeting over 150 million covered lives by 2026, which will lay a solid foundation for future growth.
Newsfilter
7.5
04-28Newsfilter
CNSide Diagnostics Secures Coverage Agreement with Blue Shield of California
  • Expanded Coverage: CNSide Diagnostics' new payer coverage agreement with Blue Shield of California increases the total covered lives for its CNSide® CSF Tumor Cell Enumeration assay from 75 million to 81 million, making significant progress towards the company's goal of 150 million covered lives by 2026, thereby enhancing patient access across the U.S.
  • Accelerated Adoption: The agreement is expected to further accelerate the adoption of CNSide across oncology centers by reducing reimbursement barriers, enabling physicians to better diagnose and treat difficult-to-diagnose CNS cancers, which will ultimately improve patient outcomes.
  • Enhanced Clinical Utility: The CNSide® assay platform has demonstrated superior clinical utility over conventional CSF cytology in nine peer-reviewed publications and the FORESEE clinical trial, enabling earlier and more accurate detection and monitoring of leptomeningeal metastases, which has been shown to reduce related healthcare costs by approximately 40%.
  • Market Impact: Since its commercial launch in 2020, over 11,000 CNSide tests have been performed at more than 120 U.S. cancer institutions, achieving a sensitivity of 92% and specificity of 95%, influencing treatment decisions in 90% of cases, thereby solidifying its market position.
Wall Street analysts forecast PSTV stock price to rise
3 Analyst Rating
Wall Street analysts forecast PSTV stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
2.00
Averages
8.00
High
19.00
Current: 0.000
sliders
Low
2.00
Averages
8.00
High
19.00
Maxim
Buy
downgrade
$12
AI Analysis
2026-04-07
Reason
Maxim
Price Target
$12
AI Analysis
2026-04-07
downgrade
Buy
Reason
Maxim lowered the firm's price target on Plus Therapeutics to $12 from $37.50 and keeps a Buy rating on the shares. Following the company's reverse stock split, the firm views its capital risk profile as elevated, driven by lower liquidity and leading to an increased cost of capital to fund operations, the analyst tells investors in a research note. Longer term, Maxim remains positive on the stock based on the LM - leptomeningeal metastases - opportunity as well as commercial upside on the CNSide opportunity.
D. Boral Capital
Buy
to
Hold
downgrade
2026-03-31
Reason
D. Boral Capital
Price Target
2026-03-31
downgrade
Buy
to
Hold
Reason
D. Boral Capital downgraded Plus Therapeutics to Hold from Buy ahead of the company's newly announced 1-for-25 reverse stock split that becomes effective April 2. While the split to preserve Nasdaq listing compliance does not alter the company's underlying enterprise value, reverse splits in small-cap biotech "typically signal capital market strain, often pressure trading liquidity, and can take meaningful time to repair the shareholder base," the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PSTV
Unlock Now

Valuation Metrics

The current forward P/E ratio for Plus Therapeutics Inc (PSTV.O) is 0.97, compared to its 5-year average forward P/E of -0.99. For a more detailed relative valuation and DCF analysis to assess Plus Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.99
Current PE
0.97
Overvalued PE
0.13
Undervalued PE
-2.11

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.79
Current EV/EBITDA
-0.53
Overvalued EV/EBITDA
0.41
Undervalued EV/EBITDA
-1.99

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
3.53
Current PS
2.31
Overvalued PS
10.06
Undervalued PS
-3.00

Financials

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Whales Holding PSTV

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Frequently Asked Questions

What is Plus Therapeutics Inc (PSTV) stock price today?

The current price of PSTV is 5.82 USD — it has decreased -9.49

What is Plus Therapeutics Inc (PSTV)'s business?

Plus Therapeutics, Inc. is a clinical-stage pharmaceutical company. The Company is engaged in developing targeted radiotherapeutics for difficult-to-treat cancers of the central nervous system. Combining image-guided local beta radiation and targeted drug delivery approaches, it is advancing a pipeline of product candidates with lead programs in leptomeningeal metastases (LM) and recurrent glioblastoma (GBM). Its lead radiotherapeutic candidate, REYOBIQ (rhenium (186Re) obisbemeda), is designed specifically for CNS cancers including GBM, LM, and pediatric brain cancers (PBC) by direct localized delivery utilizing approved standard-of-care tissue access such as with convection-enhanced delivery (CED) and intraventricular brain (Ommaya reservoir) catheters. Its radiotherapeutic candidate, Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere (188RNL-BAM), is designed to treat many solid organ cancers including primary and secondary liver cancers via intra-arterial injections.

What is the price predicton of PSTV Stock?

Wall Street analysts forecast PSTV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PSTV is8.00 USD with a low forecast of 2.00 USD and a high forecast of 19.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Plus Therapeutics Inc (PSTV)'s revenue for the last quarter?

Plus Therapeutics Inc revenue for the last quarter amounts to 1.03M USD, decreased -2.93

What is Plus Therapeutics Inc (PSTV)'s earnings per share (EPS) for the last quarter?

Plus Therapeutics Inc. EPS for the last quarter amounts to -26.13 USD, decreased -12.49

How many employees does Plus Therapeutics Inc (PSTV). have?

Plus Therapeutics Inc (PSTV) has 28 emplpoyees as of May 31 2026.

What is Plus Therapeutics Inc (PSTV) market cap?

Today PSTV has the market capitalization of 45.70M USD.