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GUTS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
0.503
Open
0.482
VWAP
0.49
Vol
1.75M
Mkt Cap
74.58M
Low
0.472
Amount
855.06K
EV/EBITDA(TTM)
--
Total Shares
153.37M
EV
28.11M
EV/OCF(TTM)
--
P/S(TTM)
8.60K
Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas.
Show More

Events Timeline

(ET)
2026-02-26
07:30:00
Fractyl Health Completes Participant Randomization in REMAIN-1 Study
select
2026-02-02 (ET)
2026-02-02
11:50:00
Fractyl Health Sees 420.59% Surge in Search Activity
select
2026-01-29 (ET)
2026-01-29
07:20:00
Fractyl Health Reports Positive Six-Month Results for Revita
select
2026-01-06 (ET)
2026-01-06
07:10:00
Fractyl Health Appoints Lara Smith Weber as CFO
select
2026-01-05 (ET)
2026-01-05
07:20:00
Fractyl Health Outlines Strategic Outlook for 2026 Focusing on Clinical Milestones
select

News

Businesswire
7.0
01-30Businesswire
DJS Law Group Investigates Claims for Fractyl Health Investors
  • Investigation Background: DJS Law Group is investigating Fractyl Health (NASDAQ: GUTS) for potential violations of securities laws, particularly whether the company issued misleading statements or failed to disclose material information to investors, indicating possible compliance risks.
  • FDA Feedback Request: On January 29, 2026, Fractyl Health requested FDA feedback on potentially reclassifying Revita under the De Novo pathway instead of seeking Premarket Approval (PMA), which has drawn significant market attention.
  • Stock Price Plunge: Following this news, shares of Fractyl Health fell by 67.48% in intraday trading on the same day, reflecting investor concerns about the company's future prospects and a sharp decline in market confidence.
  • Commitment to Legal Services: DJS Law Group focuses on enhancing investor returns through balanced counseling and aggressive advocacy, dedicated to providing high-value litigation services for clients, particularly in securities class actions and corporate governance litigation.
Newsfilter
7.0
01-29Newsfilter
DJS Law Group Investigates Claims for Fractyl Health Investors
  • Investigation Background: DJS Law Group is investigating Fractyl Health (NASDAQ: GUTS) for potential violations of securities laws, focusing on whether the company issued misleading statements or failed to disclose material information to investors.
  • FDA Feedback Request: On January 29, 2026, Fractyl Health requested FDA feedback on potentially reclassifying Revita under the De Novo pathway instead of seeking Premarket Approval (PMA), drawing significant market attention.
  • Stock Price Plunge: Following this news, shares of Fractyl Health fell by 67.48% in intraday trading on the same day, indicating substantial investor concern regarding the company's future prospects.
  • Commitment to Legal Services: DJS Law Group is dedicated to enhancing investor returns through balanced counseling and aggressive advocacy, specializing in securities class actions and corporate governance litigation.
Benzinga
8.5
01-29Benzinga
Fractyl Health Stock Plummets Amid Regulatory Strategy Shift
  • Stock Plunge: Fractyl Health's stock plummeted 64.81% to $0.644 on Thursday, hitting a 52-week low with a trading volume of 78.07 million shares, significantly exceeding the average of 3.31 million, indicating market concerns about the company's future.
  • Regulatory Strategy Shift: The company plans to shift Revita's regulatory pathway from Premarket Approval (PMA) to the De Novo pathway, aiming for a more efficient approval process, with FDA feedback expected in Q2 2026, which could impact future market access.
  • Clinical Trial Results: In the six-month randomized results from the REMAIN-1 Midpoint Cohort, Revita-treated patients experienced a 4.5% weight regain compared to 7.5% in the sham group, demonstrating significant weight maintenance effects that may enhance the product's market competitiveness.
  • Safety Profile: Revita showed favorable safety and tolerability results over six months, with no treatment-emergent serious adverse events related to the device or procedure, which is crucial for future clinical promotion and market confidence.
seekingalpha
9.5
01-29seekingalpha
Fractyl Health Shares Plunge 64% After Disappointing Data Release
  • Efficacy Data Release: Fractyl Health reported six-month data on its Revita endoscopic procedure, revealing a 4.5% weight regain in Revita patients compared to 7.5% in the placebo group, indicating the therapy's effectiveness in maintaining weight loss is below expectations.
  • Exploratory Analysis Results: Among patients who achieved above-average weight loss on GLP-1 drugs, those receiving Revita experienced a 4.2% weight regain versus 13.3% in the placebo group, suggesting potential advantages for Revita in specific patient populations, although overall efficacy remains to be validated.
  • Study Design Limitations: Fractyl noted that the midpoint cohort was not designed to be sufficiently powered for efficacy analysis, which may undermine the reliability of the results and lead to decreased market confidence in the company's future prospects.
  • Future Outlook: The company plans to release one-year midpoint cohort results in Q3 and aims for an application submission in H2, presenting an opportunity to potentially restore market confidence despite the current disappointing data.
stocktwits
9.0
01-29stocktwits
Fractyl Health Reports Positive Midpoint Data for Revita
  • Clinical Trial Results: Fractyl Health's six-month data from the REMAIN-1 Midpoint Cohort indicates that Revita-treated participants regained only 4.5% of their weight compared to 7.5% in the sham group, highlighting the device's potential for weight maintenance.
  • Lipid Improvements: Participants treated with Revita showed significant enhancements in lipid profiles, including increased HDL cholesterol and a lower triglyceride-to-HDL ratio, suggesting the device may influence metabolism through gut-mediated mechanisms.
  • Patient Feedback: Patient-reported outcomes indicated reduced cravings for sweet foods among Revita-treated participants, further supporting the device's potential in appetite regulation and opening avenues for future market applications.
  • Stock Volatility: Despite the positive study results, Fractyl Health's stock plummeted 63% in premarket trading, reflecting market concerns about the company's future prospects, although retail investor sentiment remains in 'extremely bullish' territory.
Benzinga
4.5
01-29Benzinga
U.S. Stocks Mixed in Morning Trade, Dow Jones Slightly Up
  • Market Performance: U.S. stocks opened mixed on Thursday, with the Dow Jones gaining approximately 0.1%, specifically up 0.05% to 49,042.28, while the NASDAQ fell 0.34% to 23,776.71, and the S&P 500 dipped 0.01% to 6,978.03, indicating a divergence in market sentiment.
  • Sector Dynamics: Communication services shares rose by 2.5% on Thursday, contrasting with a 1.7% decline in information technology stocks, reflecting differing investor sentiments across sectors that could influence future capital flows.
  • Tesla Investment: Tesla Inc. reported better-than-expected fourth-quarter results and announced plans to invest approximately $2 billion into CEO Elon Musk's AI startup, xAI, highlighting its strategic focus on AI development.
  • Commodity Market: On Thursday, oil prices rose by 4.9% to $66.29, gold increased by 5.2% to $5,578.80, silver climbed 6.3% to $120.735, and copper surged 10.8% to $6.5645, indicating a strong rebound in the commodities market.
Wall Street analysts forecast GUTS stock price to rise
4 Analyst Rating
Wall Street analysts forecast GUTS stock price to rise
3 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
2.00
Averages
5.00
High
8.00
Current: 0.000
sliders
Low
2.00
Averages
5.00
High
8.00
BofA
Buy
downgrade
$5 -> $2
AI Analysis
2026-01-30
Reason
BofA
Price Target
$5 -> $2
AI Analysis
2026-01-30
downgrade
Buy
Reason
BofA lowered the firm's price target on Fractyl Health to $2 from $5 and keeps a Buy rating on the shares after the company provided new, six-month randomized controlled data of its Revita procedure in weight maintenance post-discontinuation of a GLP1 therapy. The "data were not perfect," but the firm thinks the pivotal results should benefit from a much larger sample size and optimization of trial execution, says the analyst, who lowered the firm's sales forecast pending clarity on the profile strength based on additional data.
Morgan Stanley
Overweight -> Equal Weight
downgrade
$8 -> $2
2026-01-29
Reason
Morgan Stanley
Price Target
$8 -> $2
2026-01-29
downgrade
Overweight -> Equal Weight
Reason
Morgan Stanley downgraded Fractyl Health to Equal Weight from Overweight with a price target of $2, down from $8. In the randomized REMAIN-1 midpoint cohort at six months, Revita patients experienced 4.5% weight regain, which fell short of expectations and raises questions, the analyst tells investors. While the firm continues to believe success in the pivotal study is possible, it is taking a more cautious view and moving to the sidelines.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for GUTS
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Valuation Metrics

The current forward P/E ratio for Fractyl Health Inc (GUTS.O) is -3.31, compared to its 5-year average forward P/E of -1.93. For a more detailed relative valuation and DCF analysis to assess Fractyl Health Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.93
Current PE
-3.31
Overvalued PE
-0.62
Undervalued PE
-3.24

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.24
Current EV/EBITDA
-3.07
Overvalued EV/EBITDA
0.18
Undervalued EV/EBITDA
-4.66

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
4900.68
Current PS
0.00
Overvalued PS
10155.91
Undervalued PS
-354.55

Financials

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Whales Holding GUTS

N
Nantahala Capital Management, LLC
Holding
GUTS
-9.09%
3M Return

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Frequently Asked Questions

What is Fractyl Health Inc (GUTS) stock price today?

The current price of GUTS is 0.4863 USD — it has decreased -0.61

What is Fractyl Health Inc (GUTS)'s business?

Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas.

What is the price predicton of GUTS Stock?

Wall Street analysts forecast GUTS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GUTS is5.00 USD with a low forecast of 2.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Fractyl Health Inc (GUTS)'s revenue for the last quarter?

Fractyl Health Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Fractyl Health Inc (GUTS)'s earnings per share (EPS) for the last quarter?

Fractyl Health Inc. EPS for the last quarter amounts to -0.71 USD, increased 47.92

How many employees does Fractyl Health Inc (GUTS). have?

Fractyl Health Inc (GUTS) has 107 emplpoyees as of March 11 2026.

What is Fractyl Health Inc (GUTS) market cap?

Today GUTS has the market capitalization of 74.58M USD.