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OPK Overview

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$
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0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
1.460
Open
1.430
VWAP
1.43
Vol
5.23M
Mkt Cap
1.07B
Low
1.410
Amount
7.48M
EV/EBITDA(TTM)
--
Total Shares
755.09M
EV
1.07B
EV/OCF(TTM)
--
P/S(TTM)
1.88
OPKO Health, Inc. is a multinational biopharmaceutical and diagnostics company. The Company’s segments include pharmaceutical and diagnostics. The pharmaceutical segment consists of the pharmaceutical operations it operates in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its global pharmaceutical research and development operations. The diagnostics segment primarily consists of clinical laboratory operations through BioReference and its point-of-care operations. Its pharmaceutical business features Somatrogon (hGH-CTP), a once-weekly human growth hormone injection, and it is marketed under the brand name NGENLA. The Company, through its pharmaceutical division, manufactures and sells Rayaldee, a United States Food and Drug Administration (FDA) approved treatment for secondary hyperparathyroidism (SHPT) in adults with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.
Show More

Events Timeline

(ET)
2026-06-04
11:20:00
Anthropic Confidentially Files for IPO, SpaceX Plans to Raise $75B
select
2026-02-04 (ET)
2026-02-04
08:20:00
OPKO Health Expands Collaboration Agreement with Entera Bio
select
2025-10-29 (ET)
2025-10-29
16:32:53
Opko Health Announces Q3 EPS of 3 Cents, Below Consensus Estimate of 5 Cents
select
2025-10-29
08:09:58
Opko Health's ModeX Forms Licensing and Collaboration Partnership with Regeneron
select
2025-10-28 (ET)
2025-10-28
08:15:49
Opko Health's ModeX Therapeutics Launches MDX2004 Clinical Trial
select

News

Newsfilter
8.5
06-16Newsfilter
Entera Bio Reports Preclinical Data for EB612 and EB618
  • EB612 Clinical Data: Entera Bio's EB612 demonstrated robust bioavailability and sustained calcium increases across three preclinical models, with an IND application expected by late 2026, marking a significant advancement in treating hypoparathyroidism.
  • Good Tolerability: In non-human primate models, a single oral dose of EB612 significantly raised serum calcium levels for three days without safety concerns, laying a solid foundation for its future clinical applications.
  • EB618 Efficacy: As the first dual GLP-1/glucagon receptor agonist, EB618 exhibited dose-proportional pharmacokinetics in non-human primates and showed good tolerability even at doses exceeding the anticipated clinical range, supporting its potential in obesity and metabolic disorder treatments.
  • Collaborative Development Strategy: Entera's partnership with OPKO Health has expanded, with both companies advancing EB612 on a 50/50 basis, showcasing Entera's strong R&D capabilities and market prospects in the oral peptide drug sector.
Yahoo Finance
7.5
06-05Yahoo Finance
OPKO Health Deepens Partnership with Nicoya Therapeutics
  • Equity Investment Deepening: OPKO Health amended its agreement with Nicoya Therapeutics to acquire a 15% equity stake, further solidifying their partnership to commercialize RAYALDEE in Greater China, which is expected to enhance market penetration.
  • Potential Revenue Assurance: While the equity change modifies the royalty and transfer pricing arrangements, OPKO remains eligible for up to $115 million in development, regulatory, and sales-based payments, ensuring future revenue stability.
  • Market Demand Opportunity: With RAYALDEE already approved in Macau, both companies aim for additional regulatory approvals across China and related territories by 2027 to address the treatment needs of approximately 20 million adults suffering from stage 3 or 4 chronic kidney disease, showcasing significant market potential.
  • Strategic Synergy: This collaboration leverages OPKO's integrated manufacturing and supply chain capabilities alongside Nicoya's localized clinical and commercial expertise, aligning with both companies' strategy to expand global patient access to RAYALDEE, indicating substantial growth opportunities in the underserved Asian renal health market.
seekingalpha
9.5
04-29seekingalpha
OPKO Health Q1 2026 Earnings Call Insights
  • Product Development Progress: OPKO emphasized advancing its ModeX product development pipeline in Q1, with five programs now in the clinic, including the first subject dosed in the MDX2301 trial, showcasing the company's ongoing innovation in biopharmaceuticals.
  • Partnership Value: The collaboration with Regeneron is expected to provide OPKO with over $1 billion in milestones and future royalties, serving as a significant source of nondilutive capital that enhances the company's financial stability.
  • Financial Performance Overview: OPKO reported total revenues of $124.2 million for Q1 2026, with an operating loss of $51 million; however, the company is striving to achieve breakeven by mid-year, demonstrating resilience amid challenges.
  • Future Outlook and Guidance: The company guided total revenue for Q2 2026 to be between $127 million and $132 million, while facing increased R&D spending pressures, it remains committed to expanding the 4Kscore market, emphasizing confidence in future growth.
seekingalpha
9.5
04-28seekingalpha
OPKO Health Q1 Financial Results Analysis
  • Financial Performance: OPKO Health reported a Q1 GAAP EPS of -$0.07, aligning with expectations, yet revenue of $124.2 million fell 17.1% year-over-year, missing estimates by $6.57 million, indicating challenges in revenue growth.
  • Cash Position: As of March 31, 2026, OPKO's cash, cash equivalents, and marketable securities totaled $341.9 million, with approximately $92 million of common stock repurchased since the program's authorization in July 2025, reflecting proactive capital management.
  • Future Buyback Plans: In Q1 2026, OPKO repurchased $4.8 million in stock, with $108 million remaining authorized for future buybacks, demonstrating confidence in its stock value and commitment to shareholders.
  • Financial Guidance: OPKO's revenue guidance for Q2 2026 is set at $72 million to $76 million for services and $38.4 million to $42.16 million for products, with unchanged full-year guidance, though market confidence in future growth remains to be strengthened.
NASDAQ.COM
2.0
02-27NASDAQ.COM
OPKO Health (OPK) Q4 2025 Earnings Call Transcript
Globenewswire
1.0
01-06Globenewswire
OPKO Health to Participate in 44th Annual J.P. Morgan Healthcare Conference
  • Conference Participation: OPKO Health will participate in the 44th Annual J.P. Morgan Healthcare Conference from January 12-15, 2026, where management will engage in one-on-one meetings with investors, showcasing the company's strategic positioning in the biopharmaceutical and diagnostics sectors.
  • Live Webcast: On January 14 at 1:30 p.m. Pacific Time, management will participate in a fireside chat that will be webcast live, allowing investors to gain real-time insights into the company's latest developments and future directions.
  • Investor Relations Enhancement: By facilitating direct communication with investors, OPKO Health aims to strengthen its market engagement, enhance its visibility in the biopharmaceutical industry, and further drive its market expansion efforts.
  • Industry Positioning: OPKO Health is committed to establishing industry-leading positions in rapidly growing markets by leveraging its expertise in discovery, development, and commercialization, thereby demonstrating its innovative capabilities in the biopharmaceutical and diagnostics fields.
Wall Street analysts forecast OPK stock price to rise
3 Analyst Rating
Wall Street analysts forecast OPK stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
2.25
Averages
2.75
High
3.00
Current: 0.000
sliders
Low
2.25
Averages
2.75
High
3.00
Barrington
Michael Petusky
Outperform
to
Market Perform
downgrade
AI Analysis
2026-04-29
Reason
Barrington
Michael Petusky
Price Target
AI Analysis
2026-04-29
downgrade
Outperform
to
Market Perform
Reason
Barrington analyst Michael Petusky downgraded Opko Health to Market Perform from Outperform with no price target. The firm previously had expected BRH break-even or profitability in 2026 and now feels that this is "highly unlikely to materialize," the analyst tells investors. The firm also now views the upper end of the company's FY26 guidance as "seriously aspirational," the analyst added.
Barrington
Outperform
to
NULL
downgrade
2026-03-02
Reason
Barrington
Price Target
2026-03-02
downgrade
Outperform
to
NULL
Reason
Barrington lowered the firm's price target on Opko Health to $1.50 from $2.25 and keeps an Outperform rating on the shares. The company reported a better than expected Q4 report, but the way in which it achieved it is concerning, the analyst tells investors in a research note. The firm says "other revenue largely saved the quarter, but this level of performance is not sustainable."
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for OPK
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Valuation Metrics

The current forward P/E ratio for OPKO Health Inc (OPK.O) is 53.76, compared to its 5-year average forward P/E of 80.02. For a more detailed relative valuation and DCF analysis to assess OPKO Health Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
80.02
Current PE
53.76
Overvalued PE
439.98
Undervalued PE
-279.95

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-25.58
Current EV/EBITDA
-7.84
Overvalued EV/EBITDA
6.66
Undervalued EV/EBITDA
-57.83

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
1.71
Current PS
1.88
Overvalued PS
2.10
Undervalued PS
1.32

Financials

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Whales Holding OPK

R
Rubric Capital Management LP
Holding
OPK
+16.33%
3M Return

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Frequently Asked Questions

What is OPKO Health Inc (OPK) stock price today?

The current price of OPK is 1.42 USD — it has increased 0.71

What is OPKO Health Inc (OPK)'s business?

OPKO Health, Inc. is a multinational biopharmaceutical and diagnostics company. The Company’s segments include pharmaceutical and diagnostics. The pharmaceutical segment consists of the pharmaceutical operations it operates in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its global pharmaceutical research and development operations. The diagnostics segment primarily consists of clinical laboratory operations through BioReference and its point-of-care operations. Its pharmaceutical business features Somatrogon (hGH-CTP), a once-weekly human growth hormone injection, and it is marketed under the brand name NGENLA. The Company, through its pharmaceutical division, manufactures and sells Rayaldee, a United States Food and Drug Administration (FDA) approved treatment for secondary hyperparathyroidism (SHPT) in adults with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

What is the price predicton of OPK Stock?

Wall Street analysts forecast OPK stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for OPK is2.75 USD with a low forecast of 2.25 USD and a high forecast of 3.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is OPKO Health Inc (OPK)'s revenue for the last quarter?

OPKO Health Inc revenue for the last quarter amounts to 124.20M USD, decreased -17.18

What is OPKO Health Inc (OPK)'s earnings per share (EPS) for the last quarter?

OPKO Health Inc. EPS for the last quarter amounts to -0.07 USD, decreased -30.00

How many employees does OPKO Health Inc (OPK). have?

OPKO Health Inc (OPK) has 2275 emplpoyees as of June 20 2026.

What is OPKO Health Inc (OPK) market cap?

Today OPK has the market capitalization of 1.07B USD.