OPK PE Ratio & Valuation,Is OPK Overvalued

OPK Relative Valuation

OPK's fair value is calculated using relative valuation, based on historical P/E and P/S ranges and their premiums/discounts relative to a competitor average, adjusted by weights. If the market price exceeds this fair value range, OPK is overvalued; if below, it's undervalued.

Historical Valuation

OPKO Health Inc (OPK) is now in the Fair zone, suggesting that its current forward PS ratio of 1.95 is considered Fairly compared with the five-year average of 83.51. The fair price of OPKO Health Inc (OPK) is between 1.01 to 1.45 according to relative valuation methord.

Relative Value

Fair Zone

1.01-1.45

Current Price：1.38

Fair

-5.69

-13.34

EV/EBITDA

OPKO Health Inc. (OPK) has a current EV/EBITDA of -13.34. The 5-year average EV/EBITDA is -20.81. The thresholds are as follows: Strongly Undervalued below -93.49, Undervalued between -93.49 and -57.15, Fairly Valued between 15.53 and -57.15, Overvalued between 15.53 and 51.87, and Strongly Overvalued above 51.87. The current Forward EV/EBITDA of -13.34 falls within the Historic Trend Line -Fairly Valued range.

-6.55

EV/EBIT

OPKO Health Inc. (OPK) has a current EV/EBIT of -6.55. The 5-year average EV/EBIT is -1.64. The thresholds are as follows: Strongly Undervalued below -96.26, Undervalued between -96.26 and -48.95, Fairly Valued between 45.67 and -48.95, Overvalued between 45.67 and 92.98, and Strongly Overvalued above 92.98. The current Forward EV/EBIT of -6.55 falls within the Historic Trend Line -Fairly Valued range.

1.95

OPKO Health Inc. (OPK) has a current PS of 1.95. The 5-year average PS is 1.72. The thresholds are as follows: Strongly Undervalued below 0.94, Undervalued between 0.94 and 1.33, Fairly Valued between 2.11 and 1.33, Overvalued between 2.11 and 2.51, and Strongly Overvalued above 2.51. The current Forward PS of 1.95 falls within the Historic Trend Line -Fairly Valued range.

-2.73

P/OCF

OPKO Health Inc. (OPK) has a current P/OCF of -2.73. The 5-year average P/OCF is 5.14. The thresholds are as follows: Strongly Undervalued below -78.96, Undervalued between -78.96 and -36.91, Fairly Valued between 47.19 and -36.91, Overvalued between 47.19 and 89.24, and Strongly Overvalued above 89.24. The current Forward P/OCF of -2.73 falls within the Historic Trend Line -Fairly Valued range.

-59.19

P/FCF

OPKO Health Inc. (OPK) has a current P/FCF of -59.19. The 5-year average P/FCF is -2.76. The thresholds are as follows: Strongly Undervalued below -116.39, Undervalued between -116.39 and -59.58, Fairly Valued between 54.05 and -59.58, Overvalued between 54.05 and 110.87, and Strongly Overvalued above 110.87. The current Forward P/FCF of -59.19 falls within the Historic Trend Line -Fairly Valued range.

OPKO Health Inc (OPK) has a current Price-to-Book (P/B) ratio of 0.82. Compared to its 3-year average P/B ratio of 0.75 , the current P/B ratio is approximately 8.98% higher. Relative to its 5-year average P/B ratio of 1.01, the current P/B ratio is about -19.28% higher. OPKO Health Inc (OPK) has a Forward Free Cash Flow (FCF) yield of approximately -20.02%. Compared to its 3-year average FCF yield of -12.39%, the current FCF yield is approximately 61.52% lower. Relative to its 5-year average FCF yield of -7.47% , the current FCF yield is about 167.99% lower.

0.82

P/B

Median3y

0.75

Median5y

1.01

-20.02

FCF Yield

Median3y

-12.39

Median5y

-7.47

Competitors Valuation Multiple

The average P/S ratio for OPK's competitors is 1.54, providing a benchmark for relative valuation. OPKO Health Inc Corp (OPK) exhibits a P/S ratio of 1.95, which is 26.23% above the industry average. Given its robust revenue growth of -12.65%, this premium appears unsustainable.

P/S

P/E

EV/EBITDA

EV/EBIT

Revenue Growth

Market Cap

Performance Decomposition

Market capitalization of OPK decreased by 6.12% over the past 1 year. The primary factor behind the change was an decrease in P/E Change from -5.23 to -5.60.

The secondary factor is the Margin Expansion, contributed -0.49%to the performance.

Overall, the performance of OPK in the past 1 year is driven by P/E Change. Which is more unsustainable.

-12.65%

173.63M → 151.67M

Revenue Growth

-0.49%

14.33 → 14.26

Margin Expansion

7.02%

-5.23 → -5.60

P/E Change

-6.12%

1.47 → 1.38

Mkt Cap Growth

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Frequently Asked Questions

Is OPKO Health Inc (OPK) currently overvalued or undervalued?

What is OPKO Health Inc (OPK) fair value?

OPK's fair value is calculated using relative valuation, based on historical P/E and P/S ranges and their premiums/discounts relative to a competitor average , adjusted by weights. The fair price of OPKO Health Inc (OPK) is between 1.01 to 1.45 according to relative valuation methord.

How does OPK's valuation metrics compare to the industry average?

What is the current P/B ratio for OPKO Health Inc (OPK) as of Dec 15 2025?

As of Dec 15 2025, OPKO Health Inc (OPK) has a P/B ratio of 0.82. This indicates that the market values OPK at 0.82 times its book value.

What is the current FCF Yield for OPKO Health Inc (OPK) as of Dec 15 2025?

As of Dec 15 2025, OPKO Health Inc (OPK) has a FCF Yield of -20.02%. This means that for every dollar of OPKO Health Inc’s market capitalization, the company generates -20.02 cents in free cash flow.

What is the current Forward P/E ratio for OPKO Health Inc (OPK) as of Dec 15 2025?

As of Dec 15 2025, OPKO Health Inc (OPK) has a Forward P/E ratio of -5.69. This means the market is willing to pay $-5.69 for every dollar of OPKO Health Inc’s expected earnings over the next 12 months.

What is the current Forward P/S ratio for OPKO Health Inc (OPK) as of Dec 15 2025?

As of Dec 15 2025, OPKO Health Inc (OPK) has a Forward P/S ratio of 1.95. This means the market is valuing OPK at $1.95 for every dollar of expected revenue over the next 12 months.

OPK Valuation