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ADCT Overview

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Intellectia

Loading chart...

High
1.122
Open
1.090
VWAP
1.09
Vol
1.73M
Mkt Cap
138.64M
Low
1.050
Amount
1.88M
EV/EBITDA(TTM)
--
Total Shares
127.19M
EV
327.99M
EV/OCF(TTM)
--
P/S(TTM)
1.83
ADC Therapeutics SA is a Switzerland-based clinical-stage oncology drug discovery and development company. It develops antibody drug conjugates (ADCs) for the treatment of both solid and hematological cancers. It employs monoclonal antibodies specific to particular tumor antigens conjugated to a class of pyrrolobenzodiazepine (PBD)-based warheads to selectively target and kill cancer cells. The Company has multiple PBD-based ADCs in ongoing clinical trials, ranging from first in human to pivotal Phase II clinical trials, and numerous preclinical ADCs in development. Its main drug candidates are ADCT-301 for the treatment of lymphoma and leukemia and ADCT-402 for the treatment of non-Hodgkin’s lymphoma and B-cell leukemia. It serves customers in the United States, Switzerland, and the United Kingdom.
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Events Timeline

(ET)
2026-06-03
16:20:00
ADC Therapeutics Releases Phase 3 Data for Zynlonta
select
2026-05-04 (ET)
2026-05-04
07:40:00
Company Reports Q1 Revenue of $20.0M, Exceeding Expectations
select
2026-03-10 (ET)
2026-03-10
17:20:00
ADC Therapeutics Files to Sell 9.83M Common Shares
select
2026-03-10
07:40:00
Cash and Cash Equivalents Reach $261.3M, Expected to Last Until 2028
select
2026-03-10
07:40:00
ADC Therapeutics Q4 Revenue $23.06M Beats Expectations
select
2026-02-23 (ET)
2026-02-23
07:20:00
ADC Therapeutics Amends Agreement with HealthCare Royalty
select

News

Globenewswire
7.0
06-16Globenewswire
Pomerantz LLP Investigates ADC Therapeutics for Securities Fraud
  • Investigation Launched: Pomerantz LLP is investigating ADC Therapeutics SA for potential securities fraud or other unlawful business practices, aiming to protect investor rights and pursue legal remedies.
  • Clinical Trial Results: On June 3, 2026, ADC announced topline data from its Phase 3 LOTIS-5 trial showing that ZYNLONTA® combined with rituximab extended progression-free survival by 1.4 months in patients with relapsed or refractory DLBCL, but resulted in 27 deaths compared to 9 in the immunotherapy group.
  • Stock Price Plunge: Following the disappointing trial results, ADC's stock price fell by $2.05, or 66.56%, over the next two trading sessions, closing at $1.03 per share on June 5, 2026, reflecting market pessimism about the company's future prospects.
  • Legal Implications: Pomerantz LLP, recognized for its expertise in securities class action litigation, has historically recovered multimillion-dollar damages for victims of securities fraud, indicating that this investigation could lead to significant legal consequences for ADC.
Globenewswire
7.0
06-09Globenewswire
Pomerantz LLP Investigates ADC Therapeutics for Securities Fraud
  • Investigation Launched: Pomerantz LLP is investigating ADC Therapeutics SA for potential securities fraud or other unlawful business practices, aiming to protect investor rights and possibly initiate a class action lawsuit.
  • Clinical Trial Results: On June 3, 2026, ADC announced that its Phase 3 LOTIS-5 trial showed ZYNLONTA® extended progression-free survival by 1.4 months in patients with relapsed or refractory DLBCL, but the treatment group experienced significantly more deaths compared to the immunotherapy arm.
  • Stock Price Plunge: Following the trial results, ADC's stock price fell by $2.05, or 66.56%, over the next two trading sessions, closing at $1.03 per share on June 5, 2026, indicating strong market concerns regarding the treatment's efficacy.
  • Legal Implications: The investigation could lead to legal liabilities for ADC, and if fraud is confirmed, it may have significant negative impacts on the company's reputation and future financing capabilities.
seekingalpha
9.5
06-04seekingalpha
ADC Therapeutics Plummets Over 50% on Phase 3 Trial Data
  • Trial Results Impact: ADC Therapeutics' Phase 3 LOTIS-5 trial showed a median progression-free survival of 6.1 months for Zynlonta combined with rituximab, significantly higher than the control group's 4.7 months; however, the overall survival did not demonstrate superiority, leading to a drastic market reaction with shares plummeting over 50% in premarket trading.
  • Safety Concerns: While the rate of treatment-emergent adverse events was similar between the groups (98.5% vs. 97.5%), the experimental arm had a significantly higher rate of serious adverse events at 49.0%, which may affect physician acceptance of the therapy and negatively impact future sales.
  • Regulatory Path Dependency: The continued availability of Zynlonta in the U.S. hinges on positive results from confirmatory trials, and ADC Therapeutics plans to submit a supplemental Biologics License Application based on trial data; failure to secure FDA approval could severely impact the company's revenue.
  • Cost Control Measures: The company indicated it will continue its cost reduction initiatives and other value-enhancing measures to navigate current market challenges, emphasizing the need to maintain operational sustainability despite significant stock price declines.
PRnewswire
2.0
06-03PRnewswire
ADC Therapeutics Reports LOTIS-5 Trial Results for ZYNLONTA
  • Clinical Trial Success: ADC Therapeutics' LOTIS-5 trial demonstrated that the combination of ZYNLONTA and rituximab achieved statistical significance in progression-free survival (PFS) with a median PFS of 6.1 months compared to 4.7 months in the control group, indicating a significant therapeutic effect.
  • Efficacy Metrics Improvement: The combination therapy showed a complete response (CR) rate of 39.5% versus 26.7% in the control group, highlighting its potential to provide a new treatment option for patients by significantly enhancing response rates.
  • Safety Analysis: While the treatment-emergent adverse event (TEAE) rates were similar between the ZYNLONTA plus rituximab group (98.5%) and the control group (97.5%), the higher rate of serious adverse events (SAEs) in patients aged 75 and older in the ZYNLONTA group indicates a need for careful risk assessment in elderly patients.
  • FDA Application Plans: Following the positive results from LOTIS-5, ADC Therapeutics plans to submit a supplemental Biologics License Application (sBLA) in Q4 2026 and will hold a pre-sBLA meeting with the FDA in August to discuss the benefit-risk profile of this combination.
seekingalpha
9.5
05-04seekingalpha
ADC Therapeutics Q1 2026 Earnings Call Insights
  • Revenue Growth: In Q1 2026, ADC Therapeutics reported net product revenues of $20 million, up from $17.4 million in the same quarter last year, primarily driven by normal fluctuations in customer orders, indicating stable market demand and the company's ability to maintain strong sales momentum in a competitive environment.
  • Cost Management: The cost of product sales rose to $3.6 million in the first quarter, an increase of $1.6 million from the previous quarter, reflecting a shift in personnel cost allocation from research and development to commercial manufacturing, while the company actively optimizes its cost structure to maintain financial health.
  • Cash Flow Status: As of the end of Q1 2026, ADC Therapeutics had cash and cash equivalents of $231 million, down from $261.3 million at the end of 2025, yet still maintaining a healthy cash flow that supports future R&D and market expansion initiatives.
  • Future Outlook: Management expects to share top-line data for LOTIS-5 by the end of June, and if results are positive, plans to submit a supplemental biologics license application to the FDA by year-end, demonstrating the company's confidence in new product launches and its strategic grasp of market opportunities.
seekingalpha
9.5
05-04seekingalpha
ADC Therapeutics Q1 Financial Results Analysis
  • Revenue Performance: ADC Therapeutics reported a Q1 non-GAAP EPS of -$0.13 with revenues of $20.85 million, reflecting a 9.5% year-over-year decline but exceeding expectations by $0.86 million, demonstrating resilience amid market fluctuations.
  • Product Revenue Growth: The net product revenue for Q1 reached $20 million, up from $17.4 million in Q1 2025, primarily driven by normal variability in customer ordering patterns and price increases, indicating stability in product demand.
  • Decline in License Revenue: License revenues and royalties fell to $0.8 million from $5.6 million in Q1 2025, primarily due to a milestone payment received in the prior year, highlighting the volatility in revenue sources.
  • Cash Flow Status: As of March 31, 2026, cash and cash equivalents stood at $231 million, with an expected cash runway extending at least into 2028, ensuring operational stability for the company in the coming years.
Wall Street analysts forecast ADCT stock price to rise
3 Analyst Rating
Wall Street analysts forecast ADCT stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
5.00
Averages
7.33
High
10.00
Current: 0.000
sliders
Low
5.00
Averages
7.33
High
10.00
Stephens
Sudan Loganathan
Overweight
maintain
$8 -> $5
AI Analysis
2026-06-04
Reason
Stephens
Sudan Loganathan
Price Target
$8 -> $5
AI Analysis
2026-06-04
maintain
Overweight
Reason
Stephens analyst Sudan Loganathan lowered the firm's price target on ADC Therapeutics to $5 from $8 and keeps an Overweight rating on the shares after LOTIS-5 top line data that firm says "underwhelms expectations." Though the firm thinks the LOTIS-7 opportunity is "more impactful," it sees LOTIS-5 top line results as "net-negative" on penetration in the second-line space.
RBC Capital
Outperform -> Sector Perform
downgrade
$6 -> $2
2026-06-03
Reason
RBC Capital
Price Target
$6 -> $2
2026-06-03
downgrade
Outperform -> Sector Perform
Reason
RBC Capital downgraded ADC Therapeutics to Sector Perform from Outperform with a price target of $2, down from $6, after the company announced results from their LOTIS-5 trial in second-line large B-cell lymphoma. The trial did win on progression-free survival, but the benefits were modest with no clear overall survival trend, the analyst tells investors in a research note. The significant death imbalance makes the benefit/risk profile difficult to accept and adds considerable regulatory risk, the firm added.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ADCT
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Valuation Metrics

The current forward P/E ratio for ADC Therapeutics SA (ADCT.N) is 0.00, compared to its 5-year average forward P/E of -2.85. For a more detailed relative valuation and DCF analysis to assess ADC Therapeutics SA's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.85
Current PE
0.00
Overvalued PE
-0.38
Undervalued PE
-5.31

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.12
Current EV/EBITDA
-0.16
Overvalued EV/EBITDA
-0.33
Undervalued EV/EBITDA
-5.90

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
6.38
Current PS
1.12
Overvalued PS
15.34
Undervalued PS
-2.57

Financials

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Whales Holding ADCT

N
Nantahala Capital Management, LLC
Holding
ADCT
+17.19%
3M Return
R
Redmile Group, LLC
Holding
ADCT
+9.30%
3M Return
T
TCG Crossover Management, LLC
Holding
ADCT
+7.00%
3M Return

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Frequently Asked Questions

What is ADC Therapeutics SA (ADCT) stock price today?

The current price of ADCT is 1.09 USD — it has decreased -1.8

What is ADC Therapeutics SA (ADCT)'s business?

ADC Therapeutics SA is a Switzerland-based clinical-stage oncology drug discovery and development company. It develops antibody drug conjugates (ADCs) for the treatment of both solid and hematological cancers. It employs monoclonal antibodies specific to particular tumor antigens conjugated to a class of pyrrolobenzodiazepine (PBD)-based warheads to selectively target and kill cancer cells. The Company has multiple PBD-based ADCs in ongoing clinical trials, ranging from first in human to pivotal Phase II clinical trials, and numerous preclinical ADCs in development. Its main drug candidates are ADCT-301 for the treatment of lymphoma and leukemia and ADCT-402 for the treatment of non-Hodgkin’s lymphoma and B-cell leukemia. It serves customers in the United States, Switzerland, and the United Kingdom.

What is the price predicton of ADCT Stock?

Wall Street analysts forecast ADCT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ADCT is7.33 USD with a low forecast of 5.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is ADC Therapeutics SA (ADCT)'s revenue for the last quarter?

ADC Therapeutics SA revenue for the last quarter amounts to 20.85M USD, decreased -9.47

What is ADC Therapeutics SA (ADCT)'s earnings per share (EPS) for the last quarter?

ADC Therapeutics SA. EPS for the last quarter amounts to -0.21 USD, decreased -41.67

How many employees does ADC Therapeutics SA (ADCT). have?

ADC Therapeutics SA (ADCT) has 188 emplpoyees as of June 21 2026.

What is ADC Therapeutics SA (ADCT) market cap?

Today ADCT has the market capitalization of 138.64M USD.