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SGMO Overview

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ET
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Intellectia

Loading chart...

High
0.414
Open
0.412
VWAP
0.40
Vol
526.71K
Mkt Cap
153.84M
Low
0.400
Amount
213.14K
EV/EBITDA(TTM)
--
Total Shares
371.68M
EV
118.23M
EV/OCF(TTM)
--
P/S(TTM)
3.12
Sangamo Therapeutics, Inc. is a genomic medicine company. The Company’s zinc finger (ZF) epigenetic regulators are ideally suited to potentially address neurological disorders and its capsid engineering platform has demonstrated the ability to expand delivery beyond available intrathecal delivery capsids, including in the central nervous system (CNS), in preclinical studies. Zinc finger technologies are derived from naturally occurring human proteins. They are composed of a DNA-binding domain, which binds with precision to any sequence of DNA, and various functional domains (such as nucleases and transcription factors) based on therapeutic needs. Its pipeline includes Chronic Neuropathic Pain - ST-503 and Isaralgagene civaparvovec (ST-920). ST-503 is an investigational epigenetic regulator for the treatment of intractable pain due to iSFN, a type of chronic neuropathic pain. ST-920 is a wholly owned gene therapy product candidate for the treatment of Fabry disease.
Show More

Events Timeline

(ET)
2026-03-09
08:10:00
Sangamo Submits ST-920 for Accelerated Approval
select
2026-02-03 (ET)
2026-02-03
09:20:00
Sangamo Names Nikunj Jain as Interim CFO
select
2026-02-03
09:20:00
Sangamo CFO Prathyusha Duraibabu Departs, Nikunj Jain Appointed Interim CFO
select
2026-02-03
09:20:00
Sangamo Therapeutics Prices 35.19M Share Offering at $25M
select
2025-12-18 (ET)
2025-12-18
08:20:00
Sangamo Submits BLA for ST-920 Accelerated Approval to FDA
select
2025-12-02 (ET)
2025-12-02
08:31:00
Sangamo Receives FDA Fast Track Designation for ST-503 to Treat Small Fiber Neuropathy Pain
select
2025-11-21 (ET)
2025-11-21
08:08:47
Sangamo Reports FDA Approval of Rolling Submission Request for ST-920 BLA
select
2025-11-06 (ET)
2025-11-06
08:12:30
Sangamo projects operating expenses of $135M-$155M for FY25
select

News

Newsfilter
8.5
03-09Newsfilter
PinnedSangamo Advances Gene Therapy Application for Fabry Disease
  • Positive Clinical Results: The STAAR study demonstrated a positive mean annualized estimated glomerular filtration rate (eGFR) slope at 52 weeks across all dosed patients, with the FDA agreeing to use this as an endpoint to support the accelerated approval pathway for isaralgagene civaparvovec.
  • Rolling Submission Progress: Sangamo has submitted the preclinical and clinical modules of the Biologics License Application (BLA) for isaralgagene civaparvovec to the FDA, utilizing a rolling submission approach that allows for ongoing review of completed modules, thereby enhancing approval efficiency.
  • Companion Diagnostic Approval: The antibody assay companion diagnostic related to isaralgagene civaparvovec has been accepted by the FDA for Premarket Approval (PMA), which will assist in screening eligible patients for treatment, further facilitating the therapy's adoption.
  • Significant Treatment Potential: Sangamo believes that isaralgagene civaparvovec, as a one-time, well-tolerated gene therapy, can provide meaningful multi-organ clinical benefits for Fabry disease patients, potentially transforming the treatment paradigm and addressing the urgent market demand for effective therapies.
NASDAQ.COM
9.0
02-04NASDAQ.COM
Sangamo Reports Positive Data for Fabry Disease Treatment
  • Clinical Trial Results: Sangamo Therapeutics announced positive outcomes from its registrational Phase 1/2 STAAR study for Fabry disease treatment with ST-920, showing a mean annualized eGFR slope of 1.965 mL/min/1.73m² at 52 weeks across all patients, indicating improved kidney function that could enhance patient quality of life.
  • Stable Cardiac Function: The study observed stable cardiac function over one year, with consistent cardiac structural stability across clinical and demographic subgroups, further supporting the safety and efficacy of ST-920.
  • Durability of Effect: The treatment demonstrated sustained elevated alpha-galactosidase A (a-Gal A) activity for up to 4.5 years in the longest-treated patient, indicating long-lasting therapeutic effects that may provide a competitive edge in the market.
  • Market Potential: According to Grandview Research, the global Fabry disease treatment market was valued at $2.54 billion in 2023 and is projected to reach $4.93 billion by 2030, growing at a CAGR of 9.9%, presenting significant commercial opportunities for Sangamo's product.
Yahoo Finance
2.0
02-03Yahoo Finance
Sangamo Therapeutics Shares Plunge Over 31%
  • Significant Stock Drop: Sangamo Therapeutics shares fell over 31% in recent trading, indicating market concerns about the company's future prospects, which could impact investor confidence and financing capabilities.
  • Strong Market Reaction: The sharp decline in stock price may be linked to recent financial data or disappointing R&D progress, leading investors to question the sustainability of its product pipeline, thereby intensifying selling pressure.
  • Investor Sentiment Deteriorates: With the stock's steep decline, market perceptions of Sangamo's overall valuation and future growth potential have become increasingly pessimistic, potentially affecting its competitive position in the biotechnology sector.
  • Increased Financing Challenges: The significant drop in stock price may pose higher costs and greater difficulties for Sangamo in future capital raising efforts, thereby limiting its ability to fund R&D and market expansion.
seekingalpha
8.5
02-03seekingalpha
Sangamo Therapeutics Shares Plunge 28% After $25M Stock Offering
  • Stock Offering Impact: Sangamo Therapeutics priced an underwritten stock offering at $0.4719 per share for approximately 35.1 million shares and 17.8 million pre-funded warrants, leading to a ~28% drop in stock price on Tuesday, indicating negative market sentiment towards the financing.
  • Warrant Adjustments: The company announced a reduction in the exercise price of certain outstanding warrants from $1.00 to $0.4719 and extended their term to five and a half years, aiming to boost investor confidence and improve liquidity.
  • Executive Changes: The termination of Principal Financial Officer Prathyusha Duraibabu on February 3, with Nikunj Jain appointed as Interim CFO, may impact the continuity of the company's financial strategy during a critical period.
  • Cash Flow Projections: Sangamo anticipates approximately $20.9 million in cash and cash equivalents by the end of 2025, highlighting the need for careful cash flow management to support ongoing operations post-offering.
Newsfilter
8.5
02-03Newsfilter
Sangamo Therapeutics Announces Pricing of Stock Offering
  • Offering Size: Sangamo Therapeutics announced the pricing of 35,190,292 shares of common stock and 17,787,033 pre-funded warrants at $0.4719 per share, with expected gross proceeds of approximately $25 million aimed at enhancing working capital and general corporate purposes.
  • Warrant Terms: The offering includes accompanying warrants with an exercise price of $0.4719, exercisable six months post-issuance and expiring in five and a half years, providing investors with flexible investment options that may enhance market appeal.
  • Existing Warrant Adjustment: Sangamo agreed to reduce the exercise price of existing warrants held by investors from $1.00 to $0.4719 and extend their term to five and a half years, a move designed to bolster investor confidence and stimulate market activity.
  • Underwriter Role: Cantor and Wells Fargo Securities are acting as joint book-running managers for the offering, ensuring a smooth issuance process while providing the company with professional market support and resources, further enhancing Sangamo's image in the capital markets.
Globenewswire
3.5
2025-12-18Globenewswire
Sangamo Initiates BLA Submission for ST-920, Expected in Q2 2026
  • Clinical Trial Success: Sangamo's STAAR study demonstrated a positive mean annualized eGFR slope at 52 weeks across all dosed patients, with the FDA agreeing to use this as an endpoint for accelerated approval, indicating ST-920's potential as an effective treatment for Fabry disease patients.
  • Favorable Safety Profile: Isaralgagene civaparvovec exhibited a favorable safety and tolerability profile in clinical trials, suggesting its potential as a one-time gene therapy that can provide durable clinical benefits, surpassing current treatment standards for Fabry disease.
  • Accelerated Approval Pathway: Sangamo expects to complete its Biological License Application (BLA) submission to the FDA in the second quarter of 2026 using a rolling submission approach, allowing for ongoing review of completed modules, thereby expediting the approval process to meet urgent patient needs.
  • Regulatory Support: Isaralgagene civaparvovec has received Orphan Drug, Fast Track, and RMAT designations from the FDA, along with Orphan Medicinal Product designation from the European Medicines Agency, highlighting its potential value and regulatory recognition in global markets, further enhancing Sangamo's competitive position.
Wall Street analysts forecast SGMO stock price to rise
4 Analyst Rating
Wall Street analysts forecast SGMO stock price to rise
1 Buy
3 Hold
0 Sell
Hold
Current: 0.000
sliders
Low
1.00
Averages
3.75
High
10.00
Current: 0.000
sliders
Low
1.00
Averages
3.75
High
10.00
Barclays
Overweight -> Equal Weight
downgrade
$5 -> $1
AI Analysis
2025-11-07
Reason
Barclays
Price Target
$5 -> $1
AI Analysis
2025-11-07
downgrade
Overweight -> Equal Weight
Reason
Barclays downgraded Sangamo to Equal Weight from Overweight with a price target of $1, down from $5. The company's Q3 report highlighted the FDA's reaffirmation of an accelerated approval path using eGFR slope as the endpoint and its cash runway has been extended into Q1 of 2026, the analyst tells investors in a research note. Barclays steps to the sidelines pending further clarity on a Fabry deal.
Barclays
Overweight
downgrade
$9 -> $5
2025-05-14
Reason
Barclays
Price Target
$9 -> $5
2025-05-14
downgrade
Overweight
Reason
Barclays lowered the firm's price target on Sangamo to $5 from $9 and keeps an Overweight rating on the shares. The company's Q1 call provided additional color on cash runway extended into late Q3 by the capital raise, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SGMO
Unlock Now

Valuation Metrics

The current forward P/E ratio for Sangamo Therapeutics Inc (SGMO.O) is -2.19, compared to its 5-year average forward P/E of -3.94. For a more detailed relative valuation and DCF analysis to assess Sangamo Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.94
Current PE
-2.19
Overvalued PE
0.43
Undervalued PE
-8.31

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
1.54
Current EV/EBITDA
-1.98
Overvalued EV/EBITDA
28.13
Undervalued EV/EBITDA
-25.06

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.75
Current PS
1.41
Overvalued PS
10.01
Undervalued PS
1.49

Financials

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Frequently Asked Questions

What is Sangamo Therapeutics Inc (SGMO) stock price today?

The current price of SGMO is 0.4 USD — it has decreased -3.38

What is Sangamo Therapeutics Inc (SGMO)'s business?

Sangamo Therapeutics, Inc. is a genomic medicine company. The Company’s zinc finger (ZF) epigenetic regulators are ideally suited to potentially address neurological disorders and its capsid engineering platform has demonstrated the ability to expand delivery beyond available intrathecal delivery capsids, including in the central nervous system (CNS), in preclinical studies. Zinc finger technologies are derived from naturally occurring human proteins. They are composed of a DNA-binding domain, which binds with precision to any sequence of DNA, and various functional domains (such as nucleases and transcription factors) based on therapeutic needs. Its pipeline includes Chronic Neuropathic Pain - ST-503 and Isaralgagene civaparvovec (ST-920). ST-503 is an investigational epigenetic regulator for the treatment of intractable pain due to iSFN, a type of chronic neuropathic pain. ST-920 is a wholly owned gene therapy product candidate for the treatment of Fabry disease.

What is the price predicton of SGMO Stock?

Wall Street analysts forecast SGMO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SGMO is3.75 USD with a low forecast of 1.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Sangamo Therapeutics Inc (SGMO)'s revenue for the last quarter?

Sangamo Therapeutics Inc revenue for the last quarter amounts to 581.00K USD, decreased -98.82

What is Sangamo Therapeutics Inc (SGMO)'s earnings per share (EPS) for the last quarter?

Sangamo Therapeutics Inc. EPS for the last quarter amounts to -0.11 USD, decreased -375.00

How many employees does Sangamo Therapeutics Inc (SGMO). have?

Sangamo Therapeutics Inc (SGMO) has 183 emplpoyees as of March 11 2026.

What is Sangamo Therapeutics Inc (SGMO) market cap?

Today SGMO has the market capitalization of 153.84M USD.