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ATYR logo

ATYR Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
0.581
Open
0.550
VWAP
0.54
Vol
12.15M
Mkt Cap
51.72M
Low
0.520
Amount
6.60M
EV/EBITDA(TTM)
--
Total Shares
98.05M
EV
-11.08M
EV/OCF(TTM)
--
P/S(TTM)
--
aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a first-in-class biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase-derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and potentially prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0750 is a fusion protein derived from the domain of alanyl-tRNA synthetase (AARS). ATYR0750 is a novel ligand to fibroblast growth factor receptor 4 (FGFR4).
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Events Timeline

(ET)
2026-05-15
16:20:00
Major Averages Close Broadly Lower as Oil Prices Jump Again
select
2026-05-15
12:00:00
Major Averages Broadly Lower as Tech Stocks Lag
select
2026-05-15
08:40:00
aTyr Plans to Submit New Drug Application for efzofitimod Next Month
select
2026-05-11 (ET)
2026-05-11
17:10:00
aTyr Pharma Advances efzofitimod in Pulmonary Sarcoidosis
select
2026-02-03 (ET)
2026-02-03
08:10:00
aTyr Pharma to Discuss efzofitimod with FDA
select
2025-11-06 (ET)
2025-11-06
16:23:14
aTyr Pharma Announces Q3 Earnings Per Share of 26 Cents, Exceeding Consensus Estimate of 18 Cents
select

News

Globenewswire
1.0
06-26Globenewswire
Virtual Investor Conferences Forum Highlights
  • On-Demand Presentations: The Life Sciences Virtual Investor Forum held on June 24-25, 2026, is now available for on-demand viewing for 90 days, enhancing investor engagement and understanding of participating companies.
  • Company Participation: Companies such as MetaVia Inc. (NASDAQ: MTVA) and CytoSorbents Corporation (NASDAQ: CTSO) are accepting one-on-one management meeting requests, facilitating direct communication between investors and management teams.
  • Investor Materials Access: Attendees can download investor materials from the companies' resource sections, which not only increases transparency but also provides potential investors with essential decision-making support.
  • Interactive Platform Benefits: Virtual Investor Conferences offer real-time investor engagement solutions that replicate the components of on-site conferences, improving the efficiency of connections between companies and investors, thereby fostering stronger investor relations.
Globenewswire
1.0
06-23Globenewswire
Agenda Announced for Life Sciences Virtual Investor Forum
  • Forum Schedule: The Life Sciences Virtual Investor Forum, taking place on June 24-25, 2026, will bring together innovators from various companies, providing an efficient platform for direct engagement between investors and companies, expected to attract numerous individual and institutional investors.
  • Easy Participation: Investors can register for free and run an online system check to expedite participation and receive event updates, with live company presentations and one-on-one meeting arrangements enhancing the investor experience during the forum.
  • Company Showcase: The forum will feature multiple publicly traded companies, including MetaVia Inc. and CytoSorbents Corporation, covering various life sciences sectors, which is expected to provide investors with rich industry insights and investment opportunities.
  • Investor Relations Enhancement: Virtual Investor Conferences aim to improve communication efficiency between companies and investors by offering real-time interactive engagement solutions, helping companies better showcase their strategies and business development plans.
seekingalpha
9.5
05-15seekingalpha
aTyr Pharma Q1 Earnings Beat Expectations
  • Earnings Highlights: aTyr Pharma reported a Q1 GAAP EPS of -$0.11, beating expectations by $0.04, indicating improvements in cost control and operational efficiency, although the company remains in a loss position.
  • Cash Position: As of March 31, 2026, aTyr Pharma's total cash, cash equivalents, restricted cash, and available-for-sale investments amounted to $68.3 million, providing substantial funding for future R&D and operations, thereby enhancing financial stability.
  • FDA Feedback Discussion: aTyr Pharma engaged in detailed discussions with the FDA regarding Efzofitimod's Phase III trial results for pulmonary sarcoidosis, demonstrating the company's proactive approach to advancing its drug towards market approval, which could pave the way for future market access.
  • Strategic Development Focus: The company emphasized its commitment to developing treatments for pulmonary sarcoidosis, planning to accelerate subsequent clinical trials in light of FDA feedback, thereby enhancing its competitiveness in the biopharmaceutical sector.
Newsfilter
2.0
05-11Newsfilter
aTyr Pharma Advances efzofitimod Development in Pulmonary Sarcoidosis
  • Positive FDA Feedback: aTyr Pharma received encouraging feedback from the FDA regarding the development of efzofitimod for pulmonary sarcoidosis, planning to submit an IND application in June 2026, marking a strategic advancement in addressing this significant disease.
  • Clinical Trial Design: The new Phase 3 clinical trial will utilize forced vital capacity (FVC) as the primary endpoint, aiming to enroll approximately 372 patients over a 54-week period to evaluate the efficacy and safety of efzofitimod, further validating its clinical value.
  • Dosing Strategy Adjustment: The company plans to increase the dosing frequency of efzofitimod from once every four weeks to once every three weeks, aiming to enhance drug exposure and efficacy while maintaining safety, demonstrating a strong commitment to patient safety.
  • Focused Patient Population: This study will concentrate on patients with chronic, symptomatic pulmonary sarcoidosis, particularly those with FVC percent predicted ≤ 80%, aiming to improve clinical outcomes through targeted treatment and meet the urgent market demand for new therapies.
seekingalpha
9.5
03-06seekingalpha
aTyr Pharma Q4 Earnings Beat Expectations
  • Earnings Report: aTyr Pharma reported a Q4 GAAP EPS of -$0.14, beating market expectations by $0.02, indicating improvements in financial management that may bolster investor confidence.
  • Cash Reserves: As of 2025, the company holds $80.9 million in cash, cash equivalents, restricted cash, and investments, ensuring sufficient funding for future R&D and operations, supporting its long-term strategic goals.
  • FDA Meeting Plans: aTyr Pharma is set to meet with the FDA in April to discuss its lead asset, a move that could pave the way for future product approvals and enhance market recognition of its R&D capabilities.
  • Market Attention: Seeking Alpha's Quant Rating on aTyr Pharma reflects market interest in its financial performance, potentially attracting more investors to the company's growth prospects.
NASDAQ.COM
9.5
03-06NASDAQ.COM
aTYR Pharma Reports Reduced Q4 Loss
  • Financial Performance Improvement: aTYR Pharma reported a fourth-quarter loss of $13.96 million, or $0.14 per share, which is an improvement from last year's loss of $14.97 million, or $0.18 per share, indicating a positive trend in financial health.
  • Year-over-Year Comparison: Although still in the red, the narrowing of losses suggests that the company may have made progress in cost control and operational efficiency, which could enhance investor confidence in future profitability.
  • Market Reaction Expectations: With the reduction in losses, the market may adopt a more optimistic outlook on aTYR Pharma's future performance, particularly in the competitive biopharmaceutical sector, where financial improvements could attract more investor interest.
  • Strategic Adjustment Necessity: Despite the reduced losses, the company must continue to optimize its business strategy to achieve profitability, especially in terms of investments in R&D and marketing to ensure long-term sustainable growth.
Wall Street analysts forecast ATYR stock price to rise
2 Analyst Rating
Wall Street analysts forecast ATYR stock price to rise
0 Buy
2 Hold
0 Sell
Hold
Current: 0.000
sliders
Low
1.00
Averages
1.00
High
1.00
Current: 0.000
sliders
Low
1.00
Averages
1.00
High
1.00
Freedom Broker
Hold
to
Buy
upgrade
$1
AI Analysis
2026-05-20
Reason
Freedom Broker
Price Target
$1
AI Analysis
2026-05-20
upgrade
Hold
to
Buy
Reason
Freedom Broker upgraded aTyr Pharma to Buy from Hold with a price target of $3.50, up from $1. The firm says much of the uncertainty following the EFZO-FIT study failure has been removed after the FDA confirmed the rationale for continuing development of efzofitimod in chronic symptomatic pulmonary sarcoidosis. Freedom cites the drug's ultra-orphan profile and potential in orphan diseases for the upgrade.
Leerink
Faisal Khurshid
Outperform
maintain
$NULL
2025-09-15
Reason
Leerink
Faisal Khurshid
Price Target
$NULL
2025-09-15
maintain
Outperform
Reason
Leerink analyst Faisal Khurshid keeps an Outperform rating on aTyr Pharma after the company said the Phase 3 EFZO-FIT trial of efzofitimod in pulmonary sarcoidosis failed to meet its primary endpoint of steroid reduction. While aTyr plans to engage with the FDA on a potential path forward, Leerink's expectations are low given the primary endpoint miss and unclear relevance of KSQ-Lung score improvements alone, the analyst tells investors in a research note. Going into the readout, the firm expected a primary endpoint miss would see 80%-90% share downside. aTyr Pharma shares are down 82%, or $4.97, to $1.07 in early trading.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for ATYR
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Valuation Metrics

The current forward P/E ratio for aTyr Pharma Inc (ATYR.O) is 0.00, compared to its 5-year average forward P/E of -2.84. For a more detailed relative valuation and DCF analysis to assess aTyr Pharma Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.84
Current PE
0.00
Overvalued PE
-1.12
Undervalued PE
-4.57

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.33
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.67
Undervalued EV/EBITDA
-3.32

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
487.91
Current PS
0.00
Overvalued PS
1504.05
Undervalued PS
-528.23

Financials

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Quarterly

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Frequently Asked Questions

What is aTyr Pharma Inc (ATYR) stock price today?

The current price of ATYR is 0.5275 USD — it has decreased -5.72

What is aTyr Pharma Inc (ATYR)'s business?

aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging evolutionary intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a first-in-class biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase-derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and potentially prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0750 is a fusion protein derived from the domain of alanyl-tRNA synthetase (AARS). ATYR0750 is a novel ligand to fibroblast growth factor receptor 4 (FGFR4).

What is the price predicton of ATYR Stock?

Wall Street analysts forecast ATYR stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for ATYR is1.00 USD with a low forecast of 1.00 USD and a high forecast of 1.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is aTyr Pharma Inc (ATYR)'s revenue for the last quarter?

aTyr Pharma Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is aTyr Pharma Inc (ATYR)'s earnings per share (EPS) for the last quarter?

aTyr Pharma Inc. EPS for the last quarter amounts to -0.11 USD, decreased -35.29

How many employees does aTyr Pharma Inc (ATYR). have?

aTyr Pharma Inc (ATYR) has 56 emplpoyees as of June 27 2026.

What is aTyr Pharma Inc (ATYR) market cap?

Today ATYR has the market capitalization of 51.72M USD.