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PMN Overview

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ET
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ET
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Intellectia

Loading chart...

High
11.365
Open
10.870
VWAP
10.85
Vol
46.63K
Mkt Cap
96.94M
Low
10.361
Amount
505.79K
EV/EBITDA(TTM)
--
Total Shares
8.97M
EV
33.63M
EV/OCF(TTM)
--
P/S(TTM)
--
ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.
Show More

Events Timeline

(ET)
2026-05-12
06:40:00
ProMIS Expects Cash Resources to Fund Operations Through 2027
select
2026-03-25 (ET)
2026-03-25
17:30:00
ProMIS Neurosciences Files $200M Mixed Securities Shelf
select
2026-01-30 (ET)
2026-01-30
09:40:00
Promis Neurosciences Inc Trading Halted
select
2025-12-18 (ET)
2025-12-18
07:40:00
ProMIS Neurosciences Completes Enrollment of 144 Patients in Clinical Trial
select
2025-12-10 (ET)
2025-12-10
07:50:00
ProMIS Neurosciences Publishes Alzheimer's Research Findings
select
2025-12-01 (ET)
2025-12-01
08:50:00
H.C. Wainwright Raises ProMIS Price Target to $18 from $4
select

News

Newsfilter
1.0
05-28Newsfilter
ProMIS Neurosciences to Participate in Multiple Upcoming Conferences
  • Conference Participation: ProMIS Neurosciences will participate in several conferences in June 2026, including the Jefferies Global Healthcare Conference in New York, where they will present on June 4, enhancing investor confidence in their research capabilities in neurodegenerative disease treatments.
  • Product Presentation: CEO Neil Warma will discuss the EpiSelect™ platform and the Alzheimer's candidate PMN310, which selectively targets toxic amyloid-beta oligomers, potentially reducing off-target effects associated with traditional therapies, thereby improving treatment outcomes.
  • Clinical Trial Data: ProMIS expects to report blinded interim data from its PRECISE-AD Phase 1b trial in early Q3 2026, with 12-month topline data anticipated in early 2027, providing crucial insights into their Alzheimer's treatment progress for investors.
  • Market Outlook: With increasing demand for neurodegenerative disease treatments, ProMIS's innovative approach and upcoming data releases are likely to attract more investor attention, further solidifying its market position in the biotechnology sector.
seekingalpha
9.5
05-12seekingalpha
ProMIS Neurosciences Reports Q1 2026 Financial Results
  • Financial Performance: ProMIS Neurosciences reported a GAAP EPS of -$1.26 for Q1 2026, indicating challenges in profitability, although cash and cash equivalents stood at $63.8 million, reflecting $75.5 million in gross up-front proceeds from February financing.
  • Cash Flow Outlook: As of March 31, 2026, the company's cash resources are expected to fund operations through 2027, including the completion of the PRECISE-AD trial, demonstrating a proactive approach to financial management.
  • Net Loss Comparison: The net loss for Q1 2026 was $8.2 million, an increase from $7.3 million in the same period of 2025, highlighting ongoing challenges in cost control and revenue generation.
  • Financing Impact: Despite the quarterly losses, the cash flow secured through successful financing provides a buffer for future R&D and operations, indicating the company's appeal in capital markets and potential growth opportunities.
Newsfilter
9.5
05-12Newsfilter
ProMIS Secures $175 Million Financing to Support Alzheimer's Clinical Trial
  • Successful Financing: ProMIS Neurosciences has closed PIPE financing of up to $175 million, which will fund operations through 2027, particularly for the Alzheimer's Phase 1b clinical trial, reflecting strong market confidence and financial backing for the company.
  • Clinical Trial Progress: The PRECISE-AD Phase 1b trial was fully enrolled in December 2025 with 144 participants receiving treatment over 12 months, with a blinded interim analysis expected in Q3 2026, potentially providing early insights into the efficacy of PMN310, which is clinically significant.
  • Safety Concerns: Current Alzheimer's therapies carry serious safety risks, and ProMIS's PMN310 aims to selectively target toxic amyloid-beta oligomers while avoiding plaque binding, potentially reducing ARIA-related risks and enhancing patient treatment experiences.
  • Future Outlook: The company anticipates releasing 12-month topline data in early 2027, which will comprehensively assess PMN310's safety and biomarker outcomes, further validating its potential in Alzheimer's treatment and possibly transforming the existing treatment landscape.
seekingalpha
8.5
03-26seekingalpha
Promis Neurosciences Plans to Raise $200M
  • Funding Initiative: Promis Neurosciences has announced a shelf prospectus to raise up to $200 million through various securities offerings, including common shares, preferred shares, subscription receipts, debt securities, warrants, and units, aimed at enhancing the company's financial flexibility and market competitiveness.
  • Diverse Securities Offering: The securities may be sold individually or in combination, demonstrating the company's flexibility in its financing strategy, allowing it to adjust the offering structure based on market demand and investor interest, thereby maximizing the effectiveness of the fundraising.
  • Market Reaction Outlook: The market holds a cautiously optimistic view on Promis Neurosciences' funding plan, which is expected to provide essential financial support for the company's future R&D and operations, aiding its innovation and development in the neuroscience field.
  • Strategic Implications: This funding initiative not only strengthens Promis Neurosciences' capital base but also secures financial backing for future clinical trials and product development, further driving the company's growth and market share expansion in the biopharmaceutical industry.
NASDAQ.COM
9.5
03-26NASDAQ.COM
ProMIS Neurosciences Reports 2025 Financial Results and Pipeline Updates
  • Financial Performance: ProMIS Neurosciences reported a net loss of $39.72 million for FY2025, translating to a loss of $22.61 per share, a stark contrast to last year's net income of $2.78 million and earnings of $2.63 per share, indicating significant challenges in R&D investment that may impact future funding capabilities.
  • Cash Position: As of December 31, 2025, the company had $6.1 million in cash, and following a private placement in February 2026 that raised $75.5 million, these resources are expected to fund operations through 2027, ensuring the continuation of critical clinical trials.
  • Clinical Trial Progress: Following encouraging results from the Phase 1a trial of PMN310 in healthy volunteers, ProMIS initiated the PRECISE-AD Phase 1b clinical trial in Alzheimer's patients, successfully enrolling 144 participants, exceeding the target of 128, reflecting strong market interest in the therapy.
  • Market Potential: According to Grand View Research, the global Alzheimer's therapeutics market was estimated at $4.05 billion in 2022 and is projected to reach $15.19 billion by 2030, growing at a CAGR of 19.99%, presenting substantial commercial opportunities for ProMIS's product development.
moomoo
8.5
03-25moomoo
PROMIS NEUROSCIENCES INC MAY ISSUE SECURITIES WORTH UP TO $200 MILLION, ACCORDING TO SEC FILING
  • Investment Announcement: PROMIS Neurosciences is offering securities worth up to $200 million.

  • Purpose of Funding: The funds are intended to support the company's ongoing research and development efforts.

Wall Street analysts forecast PMN stock price to rise
3 Analyst Rating
Wall Street analysts forecast PMN stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
18.00
Averages
29.33
High
35.00
Current: 0.000
sliders
Low
18.00
Averages
29.33
High
35.00
Brookline
NULL
to
Buy
initiated
$40
AI Analysis
2026-05-20
Reason
Brookline
Price Target
$40
AI Analysis
2026-05-20
initiated
NULL
to
Buy
Reason
Brookline initiated coverage of ProMIS Neurosciences with a Buy rating and $40 price target.
Guggenheim
Eddie Hickman
Buy
downgrade
$6 -> $5
2025-11-18
Reason
Guggenheim
Eddie Hickman
Price Target
$6 -> $5
2025-11-18
downgrade
Buy
Reason
Guggenheim analyst Eddie Hickman lowered the firm's price target on ProMIS Neurosciences to $5 from $6 and keeps a Buy rating on the shares. ProMIS Neurosciences' Alzheimer's candidate, PMN310, is rapidly advancing toward key clinical milestones, which keeps the company on track for two pivotal data readouts in 2026, the analyst tells investors following the company's Q3 report.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PMN
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Valuation Metrics

The current forward P/E ratio for ProMIS Neurosciences Inc (PMN.O) is 0.00, compared to its 5-year average forward P/E of -1.20. For a more detailed relative valuation and DCF analysis to assess ProMIS Neurosciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.20
Current PE
0.00
Overvalued PE
0.48
Undervalued PE
-2.88

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.23
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.23
Undervalued EV/EBITDA
-2.24

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2316.36
Current PS
0.00
Overvalued PS
6837.72
Undervalued PS
-2205.01

Financials

AI Analysis
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Quarterly

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Whales Holding PMN

D
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PMN
+6.13%
3M Return

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Frequently Asked Questions

What is ProMIS Neurosciences Inc (PMN) stock price today?

The current price of PMN is 10.81 USD — it has decreased -0.55

What is ProMIS Neurosciences Inc (PMN)'s business?

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.

What is the price predicton of PMN Stock?

Wall Street analysts forecast PMN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PMN is29.33 USD with a low forecast of 18.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is ProMIS Neurosciences Inc (PMN)'s revenue for the last quarter?

ProMIS Neurosciences Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is ProMIS Neurosciences Inc (PMN)'s earnings per share (EPS) for the last quarter?

ProMIS Neurosciences Inc. EPS for the last quarter amounts to -1.26 USD, decreased -76.09

How many employees does ProMIS Neurosciences Inc (PMN). have?

ProMIS Neurosciences Inc (PMN) has 6 emplpoyees as of May 31 2026.

What is ProMIS Neurosciences Inc (PMN) market cap?

Today PMN has the market capitalization of 96.94M USD.