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PMN Overview

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ET
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Intellectia

Loading chart...

High
13.990
Open
12.780
VWAP
13.12
Vol
40.12K
Mkt Cap
113.89M
Low
12.670
Amount
526.32K
EV/EBITDA(TTM)
--
Total Shares
8.97M
EV
100.07M
EV/OCF(TTM)
--
P/S(TTM)
--
ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.
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Events Timeline

(ET)
2026-03-25
17:30:00
ProMIS Neurosciences Files $200M Mixed Securities Shelf
select
2026-01-30 (ET)
2026-01-30
09:40:00
Promis Neurosciences Inc Trading Halted
select
2025-12-18 (ET)
2025-12-18
07:40:00
ProMIS Neurosciences Completes Enrollment of 144 Patients in Clinical Trial
select
2025-12-10 (ET)
2025-12-10
07:50:00
ProMIS Neurosciences Publishes Alzheimer's Research Findings
select
2025-12-01 (ET)
2025-12-01
08:50:00
H.C. Wainwright Raises ProMIS Price Target to $18 from $4
select
2025-11-24 (ET)
2025-11-24
08:23:52
ProMIS Neurosciences declares a 1-for-20 reverse stock split.
select

News

seekingalpha
8.5
03-26seekingalpha
Promis Neurosciences Plans to Raise $200M
  • Funding Initiative: Promis Neurosciences has announced a shelf prospectus to raise up to $200 million through various securities offerings, including common shares, preferred shares, subscription receipts, debt securities, warrants, and units, aimed at enhancing the company's financial flexibility and market competitiveness.
  • Diverse Securities Offering: The securities may be sold individually or in combination, demonstrating the company's flexibility in its financing strategy, allowing it to adjust the offering structure based on market demand and investor interest, thereby maximizing the effectiveness of the fundraising.
  • Market Reaction Outlook: The market holds a cautiously optimistic view on Promis Neurosciences' funding plan, which is expected to provide essential financial support for the company's future R&D and operations, aiding its innovation and development in the neuroscience field.
  • Strategic Implications: This funding initiative not only strengthens Promis Neurosciences' capital base but also secures financial backing for future clinical trials and product development, further driving the company's growth and market share expansion in the biopharmaceutical industry.
NASDAQ.COM
9.5
03-26NASDAQ.COM
ProMIS Neurosciences Reports 2025 Financial Results and Pipeline Updates
  • Financial Performance: ProMIS Neurosciences reported a net loss of $39.72 million for FY2025, translating to a loss of $22.61 per share, a stark contrast to last year's net income of $2.78 million and earnings of $2.63 per share, indicating significant challenges in R&D investment that may impact future funding capabilities.
  • Cash Position: As of December 31, 2025, the company had $6.1 million in cash, and following a private placement in February 2026 that raised $75.5 million, these resources are expected to fund operations through 2027, ensuring the continuation of critical clinical trials.
  • Clinical Trial Progress: Following encouraging results from the Phase 1a trial of PMN310 in healthy volunteers, ProMIS initiated the PRECISE-AD Phase 1b clinical trial in Alzheimer's patients, successfully enrolling 144 participants, exceeding the target of 128, reflecting strong market interest in the therapy.
  • Market Potential: According to Grand View Research, the global Alzheimer's therapeutics market was estimated at $4.05 billion in 2022 and is projected to reach $15.19 billion by 2030, growing at a CAGR of 19.99%, presenting substantial commercial opportunities for ProMIS's product development.
moomoo
8.5
03-25moomoo
PROMIS NEUROSCIENCES INC MAY ISSUE SECURITIES WORTH UP TO $200 MILLION, ACCORDING TO SEC FILING
  • Investment Announcement: PROMIS Neurosciences is offering securities worth up to $200 million.

  • Purpose of Funding: The funds are intended to support the company's ongoing research and development efforts.

seekingalpha
9.5
03-25seekingalpha
ProMIS Neurosciences Reports FY Losses Exceeding Expectations
  • Earnings Miss: ProMIS Neurosciences reported a FY GAAP EPS of -$22.61, missing expectations by $2.57, indicating significant challenges in profitability that could undermine investor confidence.
  • Market Reaction: The disappointing earnings report may pressure ProMIS's stock price, prompting investors to monitor subsequent market dynamics and the company's response strategies to assess future investment risks.
  • Historical Financial Data: Historical financial data indicates persistent underperformance in profitability for ProMIS, reflecting high costs in R&D and marketing that could lead to long-term financial instability.
  • Quant Rating Analysis: Seeking Alpha's quant rating on ProMIS reveals a cautious market sentiment regarding its future performance, necessitating close attention to the company's strategic adjustments and changes in the market environment.
moomoo
9.5
03-25moomoo
PROMIS NEUROSCIENCES RELEASES 2025 FULL YEAR FINANCIAL RESULTS AND CORPORATE HIGHLIGHTS
  • Financial Results Announcement: PROMIS Neurosciences has released its financial results for the year 2025, detailing its performance and financial health.

  • Corporate Highlights: The announcement includes key corporate highlights that showcase the company's achievements and strategic developments over the past year.

Yahoo Finance
9.5
01-18Yahoo Finance
Phoenix Mecano Valued at CHF 769, Currently 44% Undervalued
  • Intrinsic Value Assessment: Utilizing a two-stage discounted cash flow model, Phoenix Mecano's intrinsic value is estimated at CHF 769, indicating a 44% undervaluation compared to its current share price of CHF 434, reflecting conservative market expectations for future cash flows.
  • Future Cash Flow Forecast: The projected free cash flow is expected to grow annually, starting at €28.3 million in 2026 and reaching €57 million by 2035, indicating strong growth potential in the company's profitability and cash generation capabilities.
  • Terminal Value Calculation: The estimated terminal value is €887 million, with a present value of €452 million, demonstrating the company's stable growth potential in the long term despite market volatility and industry cyclicality risks.
  • Investment Risk Warning: While the company shows strong dividend performance, it has experienced a decline in earnings over the past year, and revenue growth is expected to be below 20%, necessitating investor attention to these potential risks when assessing investment value.
Wall Street analysts forecast PMN stock price to rise
3 Analyst Rating
Wall Street analysts forecast PMN stock price to rise
3 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
18.00
Averages
29.33
High
35.00
Current: 0.000
sliders
Low
18.00
Averages
29.33
High
35.00
Guggenheim
Eddie Hickman
Buy
downgrade
$6 -> $5
AI Analysis
2025-11-18
Reason
Guggenheim
Eddie Hickman
Price Target
$6 -> $5
AI Analysis
2025-11-18
downgrade
Buy
Reason
Guggenheim analyst Eddie Hickman lowered the firm's price target on ProMIS Neurosciences to $5 from $6 and keeps a Buy rating on the shares. ProMIS Neurosciences' Alzheimer's candidate, PMN310, is rapidly advancing toward key clinical milestones, which keeps the company on track for two pivotal data readouts in 2026, the analyst tells investors following the company's Q3 report.
H.C. Wainwright
Raghuram Selvaraju
initiated
$4
2025-07-14
Reason
H.C. Wainwright
Raghuram Selvaraju
Price Target
$4
2025-07-14
initiated
Reason
H.C. Wainwright analyst Raghuram Selvaraju initiated coverage of ProMIS Neurosciences with a Buy rating and $4 price target. ProMIS is an emerging biotechnology company focused on developing novel therapeutic and vaccine-based approaches to address serious unmet medical needs in neurology, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PMN
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Valuation Metrics

The current forward P/E ratio for ProMIS Neurosciences Inc (PMN.O) is -0.69, compared to its 5-year average forward P/E of -1.15. For a more detailed relative valuation and DCF analysis to assess ProMIS Neurosciences Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-1.15
Current PE
-0.69
Overvalued PE
0.51
Undervalued PE
-2.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.19
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-0.17
Undervalued EV/EBITDA
-2.20

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2230.86
Current PS
0.00
Overvalued PS
6689.44
Undervalued PS
-2227.72

Financials

AI Analysis
Annual
Quarterly

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Whales Holding PMN

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PMN
-5.60%
3M Return

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Frequently Asked Questions

What is ProMIS Neurosciences Inc (PMN) stock price today?

The current price of PMN is 12.7 USD — it has decreased -1.4

What is ProMIS Neurosciences Inc (PMN)'s business?

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.

What is the price predicton of PMN Stock?

Wall Street analysts forecast PMN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PMN is29.33 USD with a low forecast of 18.00 USD and a high forecast of 35.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is ProMIS Neurosciences Inc (PMN)'s revenue for the last quarter?

ProMIS Neurosciences Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is ProMIS Neurosciences Inc (PMN)'s earnings per share (EPS) for the last quarter?

ProMIS Neurosciences Inc. EPS for the last quarter amounts to -5.93 USD, decreased -176.91

How many employees does ProMIS Neurosciences Inc (PMN). have?

ProMIS Neurosciences Inc (PMN) has 6 emplpoyees as of April 01 2026.

What is ProMIS Neurosciences Inc (PMN) market cap?

Today PMN has the market capitalization of 113.89M USD.