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RYTM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
97.015
Open
94.060
VWAP
92.82
Vol
1.78M
Mkt Cap
6.06B
Low
90.570
Amount
165.58M
EV/EBITDA(TTM)
--
Total Shares
68.59M
EV
5.94B
EV/OCF(TTM)
--
P/S(TTM)
26.94
Rhythm Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company's lead asset, IMCIVREE, is an MC4R agonist designed to treat hyperphagia and severe obesity, is approved by the Food and Drug Administration (FDA) to reduce excess body weight and maintain reduction long term in adults and pediatric patients aged four years and older with acquired hypothalamic obesity, adult and pediatric patients two years of age and older with syndromic or monogenic obesity due to Bardet-Biedl syndrome (BBS) or genetically confirmed pro-opiomelanocortin (POMC), including proprotein convertase subtilisin/kexin type 1 (PCSK1), deficiency or leptin receptor (LEPR) deficiency. In addition to it the Company is advancing a broad clinical development program for setmelanotide in other rare diseases, as well as investigational MC4R agonists bivamelagon and RM-718, and a preclinical suite of small molecules for the treatment of congenital hyperinsulinism.
Show More

Events Timeline

(ET)
2026-06-14
17:00:00
Rhythm Pharmaceuticals Releases Preliminary Data on Prader-Willi Syndrome Trial
select
2026-05-05 (ET)
2026-05-05
07:40:00
Rhythm Advances MC4R Agonism Pipeline
select
2026-05-05
07:40:00
Rhythm Pharmaceuticals Q1 Revenue $60.11M, Exceeds Expectations
select
2026-05-04 (ET)
2026-05-04
09:10:00
Rhythm Pharmaceuticals Presents New Data, Pediatric Patients' BMI Improves by 16.4%
select
2026-05-01 (ET)
2026-05-01
07:10:00
Rhythm Pharmaceuticals Secures EU Approval for Imcivree to Treat Acquired Hypothalamic Obesity
select
2026-04-05 (ET)
2026-04-05
21:20:00
Rhythm Pharmaceuticals Board Changes, Appoints Kim Popovits
select

News

NASDAQ.COM
9.0
11:04 AMNASDAQ.COM
Rhythm Pharmaceuticals Reports Positive Phase 2 Results for PWS Treatment
  • Clinical Trial Progress: Rhythm Pharmaceuticals presented preliminary results from the Phase 2 trial of Setmelanotide for Prader-Willi syndrome at ENDO 2026, showing a 3.60% mean reduction in BMI among 18 patients over 52 weeks, laying a strong foundation for further drug development.
  • Weight Management Efficacy: Participants exhibited a mean gain of 0.74 in lean mass and a mean loss of 4.19 in fat mass as measured by DEXA scans, indicating significant effects of Setmelanotide in weight control and body composition improvement, which may attract more patients to the drug.
  • Symptom Improvement: Patients assessed by the Hyperphagia Questionnaire showed a decrease of 7 or more points in hyperphagia, while anxiety levels also decreased, suggesting that the drug not only aids in weight management but may also improve patients' mental health.
  • Future Trial Plans: The company stated that the positive results from the Phase 2 trial will support the advancement of Setmelanotide into an upcoming Phase 3 trial, further validating its efficacy and safety in treating Prader-Willi syndrome, which could positively impact the company's future market performance.
Newsfilter
2.0
06-13Newsfilter
Rhythm Pharmaceuticals Reports Positive Phase 2 Results for PWS Treatment
  • Clinical Trial Results: In a trial involving 17 patients with Prader-Willi syndrome (PWS), treatment with setmelanotide resulted in a mean BMI reduction of 3.06%, with 6 out of 10 adult patients achieving over 2.5% BMI reduction, indicating the therapy's effectiveness in weight management and potential improvement in patients' quality of life.
  • Body Composition Improvement: Among 16 patients assessed via DEXA scans, setmelanotide led to a mean gain of 0.74% in lean mass and a mean loss of 4.19% in fat mass, demonstrating the drug's ability to facilitate weight loss while preserving muscle mass, thereby enhancing overall health outcomes for patients.
  • Emotional and Behavioral Improvements: Of the 15 patients with baseline anxiety scores above 11, 10 achieved significant improvements in anxiety and emotional distress measures, suggesting the therapy's potential to alleviate psychological burdens for both patients and their caregivers.
  • Future Development Plans: Following these positive results, Rhythm Pharmaceuticals intends to advance setmelanotide into Phase 3 trials for PWS, further validating its long-term efficacy and safety, reflecting the company's strategic commitment to addressing rare diseases.
Newsfilter
8.5
06-12Newsfilter
Rhythm Pharmaceuticals to Host Conference Call on Interim Phase 2 Results
  • Interim Results Announcement: Rhythm Pharmaceuticals will host a conference call on June 13 to discuss interim six-month results from its Phase 2 trial for Prader-Willi syndrome, which is expected to attract attention from investors and healthcare professionals, potentially impacting the company's stock price.
  • Leadership Participation: The call will feature insights from CEO David Meeker, M.D., and Dr. Jennifer Miller from the University of Florida, enhancing market confidence in the company's clinical progress and possibly fostering positive investor sentiment about future prospects.
  • IMCIVREE Drug Information: Rhythm's lead asset, IMCIVREE, has received FDA approval for treating obesity related to genetic conditions, and this meeting is anticipated to clarify its market applications, potentially driving sales growth.
  • Clinical Development Plans: The company is advancing clinical development for IMCIVREE in other rare diseases, showcasing its innovative capabilities in the biopharmaceutical sector, which may lay the groundwork for future product line expansions.
Fool
5.0
05-07Fool
Stock Investment Opportunities in May
  • TransMedics' Bright Outlook: Despite TransMedics Group (NASDAQ: TMDX) reporting Q1 earnings per share of $0.30, below the expected $0.61, its revenue increased by 21% year-over-year, indicating strong long-term potential in organ transplant technology, especially with plans for European expansion.
  • Rhythm Pharmaceuticals' Recovery: Rhythm Pharmaceuticals (NASDAQ: RYTM) recently secured FDA and European Commission approvals for Imcivree, which is expected to boost its stock price, while Japanese regulators are also reviewing the drug, impacting over 25,000 patients and highlighting significant market potential.
  • Enbridge's Stable Returns: Enbridge (NYSE: ENB), as North America's largest natural gas utility, transports 30% of crude oil and one-fifth of natural gas, providing stable investment returns, with an attractive 5.2% dividend yield that stands out in the energy sector.
  • Long-Term Growth Opportunities: Enbridge's management anticipates approximately $50 billion in growth opportunities by 2030, with investment decisions for $10 billion to $20 billion expected in the next 24 months, offering solid growth prospects despite being less explosive than TransMedics and Rhythm.
Newsfilter
9.5
05-06Newsfilter
Rhythm Pharmaceuticals Reports Strong Earnings, IMCIVREE Demand Surges
  • Earnings Beat Expectations: Rhythm Pharmaceuticals reported quarterly earnings that exceeded market expectations, reflecting strong performance in drug sales, which is likely to boost investor confidence moving forward.
  • Strong Demand for IMCIVREE: The demand for IMCIVREE continues to grow, driving revenue increases and indicating a rising market acceptance of the drug in the treatment landscape, potentially laying the groundwork for future revenue growth.
  • International Market Expansion Potential: The company plans to launch IMCIVREE in Europe and Japan, and successful entry into these markets could significantly broaden its international business footprint and enhance its competitive position globally.
  • Strategic Growth Outlook: Rhythm Pharmaceuticals' robust performance and international expansion plans suggest that its strategic decisions to meet global patient needs will contribute to long-term growth and an increase in market share.
Fool
9.5
05-06Fool
Rhythm Pharmaceuticals Surges 8% After Strong Quarterly Earnings Report
  • Significant Revenue Growth: Rhythm Pharmaceuticals reported a nearly doubled revenue of $60.1 million in Q1, driven by its Imcivree drug, surpassing the analyst consensus estimate of $57 million, indicating strong market performance in the weight-loss sector.
  • Improved Net Loss: The company's net loss widened to $56.7 million (or $0.83 per share), yet it was better than the expected loss of $0.86, suggesting some progress in cost management despite increased expenses.
  • Accelerated Market Promotion: Following FDA approval for a new indication (hypothalamic obesity), Imcivree received over 150 patient start forms within six weeks, demonstrating robust market demand and rapid promotional capabilities.
  • Strong European Market Performance: Rhythm's revenue in Europe surged by 27% quarter-over-quarter, primarily driven by strong demand in key markets like Germany and France, further boosting investor confidence in the company's growth prospects.
Wall Street analysts forecast RYTM stock price to rise
15 Analyst Rating
Wall Street analysts forecast RYTM stock price to rise
14 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
123.00
Averages
140.62
High
167.00
Current: 0.000
sliders
Low
123.00
Averages
140.62
High
167.00
Wells Fargo
NULL
to
Overweight
maintain
$144 -> $155
AI Analysis
2026-06-15
New
Reason
Wells Fargo
Price Target
$144 -> $155
AI Analysis
2026-06-15
New
maintain
NULL
to
Overweight
Reason
Wells Fargo raised the firm's price target on Rhythm Pharmaceuticals to $155 from $144 and keeps an Overweight rating on the shares. IMCIVREE's six-month Prader-Willi syndrome update further de-risks a Phase 3, showing consistent improvements across BMI and hyperphagia that support at least a 50% odds of success, the firm says. Given limited PWS value in the stock, Wells expects shares to move higher.
Canaccord
Buy
maintain
$140 -> $143
2026-05-07
Reason
Canaccord
Price Target
$140 -> $143
2026-05-07
maintain
Buy
Reason
Canaccord raised the firm's price target on Rhythm Pharmaceuticals to $143 from $140 and keeps a Buy rating on the shares. The firm said the company delivered a topline beat for 1Q26 driven by a sequential increase in BBS patients and patients on reimbursed therapy globally.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for RYTM
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Valuation Metrics

The current forward P/E ratio for Rhythm Pharmaceuticals Inc (RYTM.O) is 0.00, compared to its 5-year average forward P/E of -12.63. For a more detailed relative valuation and DCF analysis to assess Rhythm Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-12.63
Current PE
0.00
Overvalued PE
-2.88
Undervalued PE
-22.39

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-11.74
Current EV/EBITDA
-13.36
Overvalued EV/EBITDA
-0.46
Undervalued EV/EBITDA
-23.02

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
26.59
Current PS
11.30
Overvalued PS
51.73
Undervalued PS
1.46

Financials

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Whales Holding RYTM

B
Bluebox Asset Management Uk Ltd.
Holding
RYTM
+101.08%
3M Return
D
Driehaus Capital Management LLC
Holding
RYTM
+13.64%
3M Return
R
Rock Springs Capital Management LP
Holding
RYTM
+11.69%
3M Return
W
Westfield Capital Management Company, L.P.
Holding
RYTM
+8.98%
3M Return
B
Baker Bros. Advisors LP
Holding
RYTM
+6.54%
3M Return
P
Perceptive Advisors LLC
Holding
RYTM
+4.77%
3M Return

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Frequently Asked Questions

What is Rhythm Pharmaceuticals Inc (RYTM) stock price today?

The current price of RYTM is 90.86 USD — it has increased 2.81

What is Rhythm Pharmaceuticals Inc (RYTM)'s business?

Rhythm Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company's lead asset, IMCIVREE, is an MC4R agonist designed to treat hyperphagia and severe obesity, is approved by the Food and Drug Administration (FDA) to reduce excess body weight and maintain reduction long term in adults and pediatric patients aged four years and older with acquired hypothalamic obesity, adult and pediatric patients two years of age and older with syndromic or monogenic obesity due to Bardet-Biedl syndrome (BBS) or genetically confirmed pro-opiomelanocortin (POMC), including proprotein convertase subtilisin/kexin type 1 (PCSK1), deficiency or leptin receptor (LEPR) deficiency. In addition to it the Company is advancing a broad clinical development program for setmelanotide in other rare diseases, as well as investigational MC4R agonists bivamelagon and RM-718, and a preclinical suite of small molecules for the treatment of congenital hyperinsulinism.

What is the price predicton of RYTM Stock?

Wall Street analysts forecast RYTM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RYTM is140.62 USD with a low forecast of 123.00 USD and a high forecast of 167.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Rhythm Pharmaceuticals Inc (RYTM)'s revenue for the last quarter?

Rhythm Pharmaceuticals Inc revenue for the last quarter amounts to 60.11M USD, increased 83.81

What is Rhythm Pharmaceuticals Inc (RYTM)'s earnings per share (EPS) for the last quarter?

Rhythm Pharmaceuticals Inc. EPS for the last quarter amounts to -0.83 USD, increased 2.47

How many employees does Rhythm Pharmaceuticals Inc (RYTM). have?

Rhythm Pharmaceuticals Inc (RYTM) has 414 emplpoyees as of June 15 2026.

What is Rhythm Pharmaceuticals Inc (RYTM) market cap?

Today RYTM has the market capitalization of 6.06B USD.