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EWTX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
41.860
Open
40.970
VWAP
39.88
Vol
603.71K
Mkt Cap
4.37B
Low
38.770
Amount
24.07M
EV/EBITDA(TTM)
--
Total Shares
107.59M
EV
3.90B
EV/OCF(TTM)
--
P/S(TTM)
--
Edgewise Therapeutics, Inc. is a muscle disease biopharmaceutical company developing novel therapeutics for muscular dystrophies and serious cardiac conditions. The Company’s lead product candidate, sevasemten (EDG-5506), is an orally administered skeletal myosin inhibitor in late-stage clinical trials in Becker and Duchenne muscular dystrophies. Its EDG-7500 is a novel cardiac sarcomere modulator for the treatment of hypertrophic cardiomyopathy and other diseases of diastolic dysfunction, which is in Phase II clinical development. The Company is using its proprietary drug discovery platform to develop a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address a broad array of serious muscle disorders. Its platform utilizes custom-built high throughput and translatable systems that measure integrated muscle function in whole organ extracts to identify small molecule precision medicines regulating key proteins in muscle tissue.
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Events Timeline

(ET)
2026-06-16
10:31:00
Edgewise Therapeutics Shares Drop 9.9% to $31.71
select
2026-06-16
08:00:00
Edgewise Therapeutics Shares Drop 25% After EDG-7500 Trial Update
select
2026-06-16
07:30:00
Edgewise Therapeutics Reports Positive Results for EDG-7500 Trial
select
2026-06-04 (ET)
2026-06-04
14:20:00
FDA Pledges to Prevent Political Interference in Meeting with Rare Disease Nonprofits
select
link

News

Newsfilter
2.0
06-16Newsfilter
Biotech Companies Achieve Significant Milestones
  • NeOnc Breakthrough: NeOnc Technologies received IND authorization for NEO212 from the Abu Dhabi Department of Health, marking a significant international regulatory milestone that is expected to accelerate global development efforts and boost investor confidence in the company's brain cancer treatment.
  • SL Science Listing Success: SL Science completed its business combination with Horizon Space Acquisition II Corp., successfully listing on Nasdaq with an implied valuation of approximately $5.568 billion, enhancing its access to U.S. capital markets and attracting increased investor interest.
  • CervoMed Strategic Update: CervoMed showcased its neurodegenerative disease programs at the H.C. Wainwright summit, particularly highlighting progress in aligning with the FDA on a registration pathway for neflamapimod, which could propel the company toward Phase 3 trials and maintain investor attention.
  • Edgewise Cardiac Drug Progress: Edgewise Therapeutics reported positive results from its 12-week CIRRUS-HCM study, demonstrating the efficacy of EDG-7500 in hypertrophic cardiomyopathy patients, with plans to initiate Phase 3 trials in Q4 2026, potentially positioning the company as a new player in cardiovascular therapeutics.
seekingalpha
9.0
06-16seekingalpha
Edgewise Initiates Late-Stage Trial for EDG-7500 Treatment
  • Clinical Trial Progress: Edgewise Therapeutics announced it will initiate a late-stage trial for EDG-7500 later this year, following positive results from the mid-stage CIRRUS-HCM trial, although the stock fell over 10% in premarket trading, indicating market caution regarding the news.
  • Safety Assessment: According to topline data from the Phase 2 CIRRUS-HCM trial, EDG-7500 showed no new safety signals and did not affect the heart's systolic function while treating obstructive and nonobstructive forms of HCM, laying a foundation for its future clinical application.
  • Cardiac Function Metrics: Among 53 participants, there were no “meaningful” changes in left ventricular ejection fraction (LVEF), with no instances dropping below 50%, suggesting EDG-7500's potential to maintain cardiac function and positively impact patients with hypertrophic cardiomyopathy.
  • Future Development Plans: Edgewise plans to start Phase 3 development for EDG-7500 in Q4 2026, with CEO Kevin Koch emphasizing that this research marks an important milestone for both the company and the HCM community, demonstrating EDG-7500's potential to address diastolic dysfunction without significant impact on LVEF.
PRnewswire
9.0
06-16PRnewswire
Edgewise Therapeutics Reports Positive Phase 2 Results for EDG-7500 in HCM Patients
  • Clinical Trial Results: Edgewise Therapeutics announced positive 12-week Phase 2 results for EDG-7500 in obstructive and nonobstructive hypertrophic cardiomyopathy (HCM) patients, with 90% of patients showing significant improvements in hemodynamic measures and 74% achieving normalization or a 50% reduction in NT-proBNP levels.
  • Safety Assessment: Among 53 participants, EDG-7500 was generally well tolerated, with nearly all adverse events classified as mild to moderate, and no significant reductions in left ventricular ejection fraction observed, indicating the drug's safety in terms of cardiac function.
  • Dose Response: In patients with obstructive HCM, EDG-7500 demonstrated significant reductions in LVOT-G, with 70% of patients showing at least one class improvement in New York Heart Association functional class, highlighting the drug's potential in enhancing cardiac function.
  • Future Development Plans: Based on the data from CIRRUS-HCM, Edgewise plans to initiate Phase 3 clinical trials for EDG-7500 in the fourth quarter of 2026, aiming to further validate its therapeutic potential in hypertrophic cardiomyopathy treatment.
PRnewswire
5.0
06-03PRnewswire
Edgewise Grants Stock Options to New Employees
  • Stock Option Grant: On May 29, 2026, Edgewise Therapeutics granted a total of 74,000 inducement stock options to four new non-executive employees, aimed at attracting talent and strengthening the team.
  • Exercise Price Setting: Each inducement stock option has an exercise price of $34.16 per share, equal to the closing price of Edgewise common stock on the grant date, ensuring alignment of employee interests with those of shareholders.
  • Vesting Arrangement: The vesting schedule for these stock options stipulates that 25% will vest on each employee's one-year anniversary, with the remaining shares vesting monthly, thereby incentivizing continued contributions during employment.
  • Compliance Assurance: This stock option grant complies with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's strategic considerations and commitment to attracting and retaining key talent.
stocktwits
8.5
06-01stocktwits
Servier Acquires Edgewise's Muscular Dystrophy Operations
  • Significant Deal Size: Servier's acquisition of Edgewise Therapeutics' muscular dystrophy operations for $2.65 billion, including the lead drug Sevasemten, is expected to close in Q3 2026, indicating Servier's strategic expansion in rare neuromuscular disorders.
  • Stock Surge: Edgewise Therapeutics (EWTX) shares soared over 20% on Monday, potentially marking the largest single-day gain in six months, reflecting strong market sentiment towards the deal, and if it closes at current levels, it could push the stock to a record high.
  • Drug Development Outlook: Sevasemten, an investigational oral therapy designed to protect muscles from contraction-related damage, is currently undergoing pivotal trials for Becker muscular dystrophy and a Phase 2 study for Duchenne muscular dystrophy, addressing a significant unmet need in the market with no approved treatments available.
  • Positive Safety Data: The MESA extension study indicates that Sevasemten maintained stable physical function in Becker muscular dystrophy patients for up to 3.5 years, with a favorable cardiac safety profile over 12 months, showing improved cardiac function in some patients, thereby enhancing the drug's market appeal.
PRnewswire
8.5
06-01PRnewswire
Edgewise to Sell Muscle Disease Business for $1.55 Billion
  • Significant Transaction Value: Edgewise Therapeutics has entered into an agreement with Servier to sell its muscle disease business for $1.55 billion in upfront cash, with potential milestone payments of up to $1.1 billion, leading to a total potential consideration of $2.65 billion, which will significantly enhance Edgewise's financial flexibility.
  • Strategic Focus Shift: Following the transaction, Edgewise will pivot to focus on cardiovascular therapies, developing drugs such as EDG-7500 and EDG-15400, which is expected to accelerate the unlocking of its cardiovascular pipeline's potential and enhance its competitive position in the market.
  • Clinical Data Reporting Plans: Edgewise plans to report 12-week data from the CIRRUS-HCM trial in Q2 2026, which will provide critical insights for the further development of its cardiac drugs, thereby advancing its clinical progress.
  • Employee Transition Assurance: All Edgewise employees supporting the muscle disease business will receive comparable offers from Servier, ensuring continuity of operations and future commercial execution, reflecting a commitment to talent retention and strategic integration.
Wall Street analysts forecast EWTX stock price to rise
9 Analyst Rating
Wall Street analysts forecast EWTX stock price to rise
8 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
16.00
Averages
38.14
High
51.00
Current: 0.000
sliders
Low
16.00
Averages
38.14
High
51.00
RBC Capital
NULL
to
Outperform
maintain
$48 -> $59
AI Analysis
2026-06-17
Reason
RBC Capital
Price Target
$48 -> $59
AI Analysis
2026-06-17
maintain
NULL
to
Outperform
Reason
RBC Capital raised the firm's price target on Edgewise Therapeutics to $59 from $48 and keeps an Outperform rating on the shares. The company reported 12 week results from their HCM trial for '7500, and the firm believes the data delivered on both compelling safety and efficacy, with the potential to allow the company to design a Phase 3 truak without titration echos and ultimately deliver on a convenient real-world safety profile, the analyst tells investors in a research note. Edgewise is a compelling cardiology story with '7500's preferred profile enabling over $3B in revenues and an emerging pipeline, the firm added.
Goldman Sachs
Paul Choi
Neutral
maintain
$20 -> $32
2026-06-17
Reason
Goldman Sachs
Paul Choi
Price Target
$20 -> $32
2026-06-17
maintain
Neutral
Reason
Goldman Sachs analyst Paul Choi raised the firm's price target on Edgewise Therapeutics to $32 from $20 and keeps a Neutral rating on the shares. Phase 2 CIRRUS-HCM data for EDG-7500 showed functional and biomarker improvements in both oHCM and nHCM with generally clean safety, the analyst tells investors in a research note. Uncertainty around whether the HCM treatment paradigm can meaningfully shift away from routine echo monitoring contributed to intraday volatility despite overall positive de-risking from the readout, the firm says.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for EWTX
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Valuation Metrics

The current forward P/E ratio for Edgewise Therapeutics Inc (EWTX.O) is 0.00, compared to its 5-year average forward P/E of -9.59. For a more detailed relative valuation and DCF analysis to assess Edgewise Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-9.59
Current PE
0.00
Overvalued PE
-4.73
Undervalued PE
-14.45

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-6.01
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-1.68
Undervalued EV/EBITDA
-10.34

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
21.90
Current PS
83.86
Overvalued PS
89.86
Undervalued PS
-46.05

Financials

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Whales Holding EWTX

N
Novo Holdings A/S
Holding
EWTX
+29.41%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
EWTX
+26.83%
3M Return
D
Driehaus Capital Management LLC
Holding
EWTX
+23.06%
3M Return
P
Perceptive Advisors LLC
Holding
EWTX
+21.31%
3M Return
D
Deerfield Management Company, L.P.
Holding
EWTX
+18.91%
3M Return
B
Braidwell LP
Holding
EWTX
+18.51%
3M Return

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Frequently Asked Questions

What is Edgewise Therapeutics Inc (EWTX) stock price today?

The current price of EWTX is 38.995 USD — it has decreased -4.02

What is Edgewise Therapeutics Inc (EWTX)'s business?

Edgewise Therapeutics, Inc. is a muscle disease biopharmaceutical company developing novel therapeutics for muscular dystrophies and serious cardiac conditions. The Company’s lead product candidate, sevasemten (EDG-5506), is an orally administered skeletal myosin inhibitor in late-stage clinical trials in Becker and Duchenne muscular dystrophies. Its EDG-7500 is a novel cardiac sarcomere modulator for the treatment of hypertrophic cardiomyopathy and other diseases of diastolic dysfunction, which is in Phase II clinical development. The Company is using its proprietary drug discovery platform to develop a pipeline of precision medicine product candidates that target key muscle proteins and modulators to address a broad array of serious muscle disorders. Its platform utilizes custom-built high throughput and translatable systems that measure integrated muscle function in whole organ extracts to identify small molecule precision medicines regulating key proteins in muscle tissue.

What is the price predicton of EWTX Stock?

Wall Street analysts forecast EWTX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for EWTX is38.14 USD with a low forecast of 16.00 USD and a high forecast of 51.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Edgewise Therapeutics Inc (EWTX)'s revenue for the last quarter?

Edgewise Therapeutics Inc revenue for the last quarter amounts to -54.12M USD, increased 17.75

What is Edgewise Therapeutics Inc (EWTX)'s earnings per share (EPS) for the last quarter?

Edgewise Therapeutics Inc. EPS for the last quarter amounts to -42803000.00 USD, increased 12.91

How many employees does Edgewise Therapeutics Inc (EWTX). have?

Edgewise Therapeutics Inc (EWTX) has 146 emplpoyees as of July 01 2026.

What is Edgewise Therapeutics Inc (EWTX) market cap?

Today EWTX has the market capitalization of 4.37B USD.