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PTCT Overview

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ET
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ET
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Intellectia

Loading chart...

High
68.115
Open
67.910
VWAP
66.21
Vol
905.69K
Mkt Cap
5.44B
Low
64.851
Amount
59.97M
EV/EBITDA(TTM)
7.07
Total Shares
82.77M
EV
6.33B
EV/OCF(TTM)
8.90
P/S(TTM)
3.31
PTC Therapeutics, Inc. is a global biopharmaceutical company. The Company is focused on the discovery, development, and commercialization of clinically differentiated medicines that provide benefits to children and adults living with rare disorders. Its diversified therapeutic portfolio includes several commercial products and product candidates in various stages of development, including discovery, research and clinical stages, focused on the development of new treatments for multiple therapeutic areas for rare diseases relating to neurology and metabolism. It has two products, Translarna (ataluren) and Emflaza (deflazacort), for the treatment of Duchenne muscular dystrophy (DMD) a rare, life-threatening disorder. Its Upstaza, a gene therapy for the treatment of Aromatic L-Amino Decarboxylase (AADC) deficiency, a rare central nervous system (CNS) disorder. Its Tegsedi and Waylivra are for the treatment of rare diseases. Its Evrysdi, a treatment for spinal muscular atrophy (SMA).
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Events Timeline

(ET)
2026-03-08
22:30:00
KKR Plans to Sell CoolIT Systems for Over $3B
select
2026-03-08
17:00:00
Dr. Vinay Prasad to Leave Agency at End of April
select
link
2026-02-19 (ET)
2026-02-19
16:10:00
Sephience Q4 Revenue $164.7M, Below Consensus
select

News

CNBC
9.0
03-05CNBC
UniQure's Gene Therapy Faces FDA Challenges
  • FDA Study Requirement: The U.S. FDA has mandated that UniQure conduct a placebo-controlled trial to validate the efficacy of its gene therapy for Huntington's disease, despite the company's claims that such a trial is unethical due to the need for prolonged general anesthesia.
  • Clinical Trial Controversy: An FDA official indicated that UniQure's clinical trial data does not meet approval criteria, suggesting that the company may be aware of its earlier trial failures and has not pursued necessary clinical studies.
  • Stock Price Fluctuation: Despite facing challenges from the FDA, UniQure's stock rose over 10% on Thursday, although it has fallen 58% this year, reflecting market concerns regarding the therapy's prospects.
  • Regulatory Tensions: The relationship between UniQure and the FDA is increasingly strained, with the agency facing criticism for recent drug application rejections, and UniQure accusing the FDA of reversing its acceptance standards for the company's clinical trial data.
Fool
6.5
03-03Fool
Palo Alto Investors Increases Stake in PTC Therapeutics
  • Share Increase: Palo Alto Investors LP reported a purchase of 41,303 shares of PTC Therapeutics in its SEC filing dated February 17, 2026, with an estimated transaction value of $3.00 million, reflecting confidence in the company's future prospects.
  • Value Appreciation: As of the end of Q4 2025, Palo Alto's stake in PTC Therapeutics was valued at $68.66 million, an increase of $15.72 million from the previous period, indicating both stock price appreciation and positive investor sentiment.
  • Strong Market Performance: As of February 17, 2026, PTC Therapeutics shares were priced at $69.17, up 39.9% over the past year, outperforming the S&P 500 by 21.57 percentage points, showcasing its competitive edge in the biotech sector.
  • Company Overview: PTC Therapeutics specializes in treatments for rare diseases, offering several commercialized therapies and investigational candidates, aiming to address unmet medical needs and drive long-term growth through innovation and strategic collaborations.
PRnewswire
1.0
02-23PRnewswire
PTC Therapeutics Announces Upcoming Conference Schedule
  • Conference Schedule: PTC Therapeutics will participate in three significant healthcare conferences on March 2, March 10, and March 11, 2026, showcasing its latest advancements in rare disease treatments.
  • Live Webcast: Presentations will be webcast live on PTC's investor section of its website and archived for 30 days post-event, ensuring that investors unable to attend can still access the information.
  • Company Mission: PTC is dedicated to providing clinically differentiated medicines for patients with rare disorders, advancing a diversified pipeline to address unmet medical needs, highlighting its strategic positioning in the biopharmaceutical sector.
  • Science and Business Integration: The company plans to leverage its scientific expertise and global commercial infrastructure to optimize value for patients and stakeholders, further solidifying its competitive advantage in the biopharmaceutical industry.
seekingalpha
9.5
02-20seekingalpha
PTC Therapeutics Q4 2025 Earnings Call Highlights
  • Successful Global Launch: PTC Therapeutics' Sephience received approvals and launched in the U.S., EU, and Japan, generating $92 million in revenue in Q4 2025, establishing itself as a cornerstone for future growth, indicating strong market demand and broad patient acceptance.
  • Financial Performance Exceeds Expectations: The company reported $263 million in net product and royalty revenue for Q4 2025, with total revenue for the year reaching $831 million, surpassing the guidance of $750 million to $800 million, reflecting exceptional execution in product sales and cost management.
  • Strong Cash Position: PTC Therapeutics ended 2025 with $1.95 billion in cash, bolstered by the $240 million sale of Evrysdi royalties, ensuring financial flexibility for future R&D and market expansion initiatives.
  • Optimistic 2026 Outlook: The company anticipates product revenue of $700 million to $800 million in 2026, representing a year-over-year growth of 19% to 36%, with potential for cash flow breakeven, demonstrating management's confidence in future growth and effective strategic planning.
Newsfilter
8.5
02-18Newsfilter
Phenylketonuria Treatment Market Outlook Analysis
  • Market Size Growth: The phenylketonuria treatment market is expected to continue growing by 2034, with the U.S. holding the largest market size, as evidenced by 18,800 diagnosed PKU cases in 2024, indicating strong demand and economic opportunities in this sector.
  • Emerging Therapies Development: New therapies such as NGGT002, JNT-517, and Pegvaliase are currently in clinical trials and are anticipated to enter the market in the coming years, significantly improving treatment options for patients and driving market transformation.
  • Increased Screening Rates: The expansion of newborn screening programs globally has led to higher early diagnosis rates of PKU, resulting in more patients entering care pathways, thereby enhancing the market's growth potential and meeting rising healthcare demands.
  • Regulatory Support: The approvals of PTC Therapeutics' SEPHIENCE and BioMarin's Pegvaliase by the FDA and Japan's Ministry of Health signify an improved regulatory environment, providing favorable conditions for new therapies' market entry and fostering innovation and development in the industry.
Benzinga
2.0
02-13Benzinga
PTC Therapeutics Withdraws New Drug Application for Translarna
  • Withdrawal of NDA: PTC Therapeutics has withdrawn its New Drug Application for Translarna (ataluren) after receiving FDA feedback indicating that the submitted data was unlikely to meet effectiveness standards, marking a significant setback after over two decades of development for this Duchenne muscular dystrophy (DMD) therapy.
  • Poor Market Performance: PTC's stock closed 5.16% lower on Thursday, currently trading 10.0% below its 20-day simple moving average, indicating a bearish short-term trend, and significantly underperforming compared to the flat performance of the healthcare sector.
  • Future Earnings Outlook: PTC is set to report earnings on February 19, 2026, with an estimated loss of 34 cents per share and revenue forecasted at $290.76 million, up from $213.17 million year-over-year, suggesting potential growth opportunities despite current challenges.
  • Analyst Rating Changes: While PTC's stock carries a
Wall Street analysts forecast PTCT stock price to rise
14 Analyst Rating
Wall Street analysts forecast PTCT stock price to rise
8 Buy
5 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
54.00
Averages
78.18
High
118.00
Current: 0.000
sliders
Low
54.00
Averages
78.18
High
118.00
Morgan Stanley
Overweight
maintain
$90 -> $92
AI Analysis
2026-02-23
Reason
Morgan Stanley
Price Target
$90 -> $92
AI Analysis
2026-02-23
maintain
Overweight
Reason
Morgan Stanley raised the firm's price target on PTC Therapeutics to $92 from $90 and keeps an Overweight rating on the shares. The firm updated its model for actuals and management commentary following PTC's Q4 results call.
Barclays
Eliana Merle
Overweight
maintain
$119 -> $120
2026-02-23
Reason
Barclays
Eliana Merle
Price Target
$119 -> $120
2026-02-23
maintain
Overweight
Reason
Barclays analyst Eliana Merle raised the firm's price target on PTC Therapeutics to $120 from $119 and keeps an Overweight rating on the shares post the Q4 report. The firm sees potential upside to the company's 2026 revenue outlook.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PTCT
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Valuation Metrics

The current forward P/E ratio for PTC Therapeutics Inc (PTCT.O) is -50.06, compared to its 5-year average forward P/E of -12.54. For a more detailed relative valuation and DCF analysis to assess PTC Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-12.54
Current PE
-50.06
Overvalued PE
-0.35
Undervalued PE
-24.74

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
23.86
Current EV/EBITDA
147.89
Overvalued EV/EBITDA
222.23
Undervalued EV/EBITDA
-174.52

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
4.18
Current PS
7.00
Overvalued PS
5.36
Undervalued PS
3.01

Financials

AI Analysis
Annual
Quarterly

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Whales Holding PTCT

H
Hood River Capital Management LLC
Holding
PTCT
+18.06%
3M Return
D
Driehaus Capital Management LLC
Holding
PTCT
+11.26%
3M Return
J
Jefferies Financial Group Inc.
Holding
PTCT
+3.45%
3M Return
T
Tang Capital Management, LLC
Holding
PTCT
+2.62%
3M Return
A
Armistice Capital LLC
Holding
PTCT
-6.08%
3M Return

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Frequently Asked Questions

What is PTC Therapeutics Inc (PTCT) stock price today?

The current price of PTCT is 65.67 USD — it has decreased -4.22

What is PTC Therapeutics Inc (PTCT)'s business?

PTC Therapeutics, Inc. is a global biopharmaceutical company. The Company is focused on the discovery, development, and commercialization of clinically differentiated medicines that provide benefits to children and adults living with rare disorders. Its diversified therapeutic portfolio includes several commercial products and product candidates in various stages of development, including discovery, research and clinical stages, focused on the development of new treatments for multiple therapeutic areas for rare diseases relating to neurology and metabolism. It has two products, Translarna (ataluren) and Emflaza (deflazacort), for the treatment of Duchenne muscular dystrophy (DMD) a rare, life-threatening disorder. Its Upstaza, a gene therapy for the treatment of Aromatic L-Amino Decarboxylase (AADC) deficiency, a rare central nervous system (CNS) disorder. Its Tegsedi and Waylivra are for the treatment of rare diseases. Its Evrysdi, a treatment for spinal muscular atrophy (SMA).

What is the price predicton of PTCT Stock?

Wall Street analysts forecast PTCT stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PTCT is78.18 USD with a low forecast of 54.00 USD and a high forecast of 118.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is PTC Therapeutics Inc (PTCT)'s revenue for the last quarter?

PTC Therapeutics Inc revenue for the last quarter amounts to 164.68M USD, decreased -22.75

What is PTC Therapeutics Inc (PTCT)'s earnings per share (EPS) for the last quarter?

PTC Therapeutics Inc. EPS for the last quarter amounts to -1.64 USD, increased 92.94

How many employees does PTC Therapeutics Inc (PTCT). have?

PTC Therapeutics Inc (PTCT) has 991 emplpoyees as of March 12 2026.

What is PTC Therapeutics Inc (PTCT) market cap?

Today PTCT has the market capitalization of 5.44B USD.