Xeris Pharmaceuticals to Announce Q4 Earnings on March 2
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 1 hour ago
0mins
Should l Buy XERS?
Source: seekingalpha
- Earnings Announcement: Xeris Pharmaceuticals is set to release its Q4 2023 earnings report on March 2 before market open, with a consensus EPS estimate of $0.04, reflecting a significant year-over-year increase of 233.3%, indicating a notable improvement in profitability.
- Revenue Growth Expectations: Analysts forecast that Xeris will achieve $86 million in revenue for Q4, representing a 43.1% year-over-year growth, which highlights the company's strong performance in market demand and product sales, potentially boosting investor confidence.
- Pipeline Opportunities: Xeris Biopharma shows strong momentum with its Recorlev product, indicating potential in drug development and market expansion, which could support future revenue growth.
- Rating Downgrade Impact: Despite the strong growth outlook, Xeris Biopharma's rating has been downgraded, reflecting market caution regarding the company's future performance, which may exert short-term pressure on its stock price.
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Analyst Views on XERS
Wall Street analysts forecast XERS stock price to rise
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 6.740
Low
9.00
Averages
9.67
High
10.00
Current: 6.740
Low
9.00
Averages
9.67
High
10.00
About XERS
Xeris Biopharma Holdings, Inc. is a biopharmaceutical company focused on improving patient lives by developing and commercializing products across a range of therapies. It has three commercially available products: Recorlev, Gvoke, and Keveyis. Recorlev is for the treatment of endogenous Cushing’s syndrome. Gvoke is a ready-to-use liquid glucagon for the treatment of severe hypoglycemia. Keveyis is a therapy for primary periodic paralysis. It also has a pipeline of development programs led by XP-8121, a phase III-ready, once-weekly subcutaneous injection for hypothyroidism. It is pursuing formulation and development partnerships to apply its XeriSol and XeriJect formulation technologies to enhance the drug delivery and clinical profile of other companies’ proprietary drugs and biologics. Recorlev is a cortisol synthesis inhibitor approved for the treatment of endogenous hypercortisolemia in adults with Cushing's syndrome for whom surgery is not an option or has not been curative.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Earnings Announcement: Xeris Pharmaceuticals is set to release its Q4 2023 earnings report on March 2 before market open, with a consensus EPS estimate of $0.04, reflecting a significant year-over-year increase of 233.3%, indicating a notable improvement in profitability.
- Revenue Growth Expectations: Analysts forecast that Xeris will achieve $86 million in revenue for Q4, representing a 43.1% year-over-year growth, which highlights the company's strong performance in market demand and product sales, potentially boosting investor confidence.
- Pipeline Opportunities: Xeris Biopharma shows strong momentum with its Recorlev product, indicating potential in drug development and market expansion, which could support future revenue growth.
- Rating Downgrade Impact: Despite the strong growth outlook, Xeris Biopharma's rating has been downgraded, reflecting market caution regarding the company's future performance, which may exert short-term pressure on its stock price.
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- Patent Infringement Lawsuit: Xeris Biopharma and its subsidiaries have filed a patent infringement lawsuit against Torrent Pharmaceuticals and Somerset Therapeutics to prevent them from manufacturing and selling a generic version of Recorlev®, aiming to protect its patents until March 2040.
- Legal Basis: The lawsuit is filed under the Hatch-Waxman Act, with Xeris seeking an injunction to stop ANDA filers from producing, using, or selling generics before patent expiration, demonstrating the company's strong intent to protect its intellectual property.
- Market Impact: Xeris's CEO expressed confidence in the quality of the intellectual property for Recorlev, indicating that this lawsuit is not only a firm response to competitors but may also influence the sales and pricing strategies of Recorlev in the market.
- Future Outlook: Xeris anticipates receiving additional Notice Letters from ANDA filers, indicating interest in generic versions of Recorlev, and plans to continue enforcing its intellectual property rights to maintain its competitive edge in the biopharmaceutical sector.
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- Earnings Release Schedule: Xeris Biopharma will announce its Q4 and full-year 2025 financial results before the U.S. market opens on March 2, 2026, reflecting the company's commitment to transparency and investor communication.
- Conference Call Details: Management will host a conference call at 8:30 a.m. Eastern Time to discuss financial and operational results, aiming to enhance investor understanding and confidence in the company's performance.
- Product Line Overview: Xeris currently has three commercially available products, including Recorlev® for Cushing's syndrome, Gvoke® for severe hypoglycemia, and Keveyis® for primary periodic paralysis, indicating a diversified portfolio in the biopharmaceutical sector.
- R&D Pipeline Progress: Xeris's pipeline includes XP-8121, a Phase 3-ready once-weekly subcutaneous injection for hypothyroidism, showcasing the company's potential in addressing thyroid disorders and further solidifying its market position.
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- Earnings Release Schedule: Xeris Biopharma Holdings will announce its fourth quarter and full year 2025 financial results before the U.S. market opens on March 2, 2026, highlighting its ongoing growth and innovation in the biopharmaceutical sector.
- Conference Call Timing: Management will host a conference call and webcast at 8:30 a.m. ET on that day to discuss the company's financial and operational results, aiming to enhance investor understanding and confidence in the company's performance.
- Registration Participation Method: Investors can pre-register for the conference call via the provided link, with a recommendation to register at least ten minutes in advance to ensure smooth participation, reflecting the company's commitment to investor relations.
- Product and Pipeline Overview: Xeris currently has three commercially available products, including Recorlev® for Cushing's syndrome, Gvoke® for severe hypoglycemia, and Keveyis® for primary periodic paralysis, along with multiple development programs like XP-8121, showcasing its robust product pipeline and market potential.
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- ETF Upside Potential: The iShares U.S. Pharmaceuticals ETF (IHE) has an implied analyst target price of $96.28 per unit, while trading at $86.15, indicating an 11.76% upside, reflecting market optimism about the ETF's future performance.
- MBX Stock Analysis: MBX BIOSCIENCES INC (MBX) trades at $35.83, with an analyst target price of $60.55, suggesting a potential upside of 69.01%, showcasing investor confidence in its future prospects.
- CRNX Stock Outlook: Crinetics Pharmaceuticals Inc (CRNX) has a current price of $51.32 and an analyst target of $83.46, indicating a 62.63% upside, reflecting positive market sentiment regarding its product and R&D advancements.
- XERS Investment Opportunity: Xeris Biopharma Holdings Inc (XERS) is priced at $7.14, with an analyst target of $11.14, showing a 56.05% upside, indicating analysts' optimism about its growth potential.
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- Revenue Growth: Xeris anticipates total revenue of $292 million for 2025, exceeding the guidance range of $285-$290 million and reflecting a 44% increase from the previous year, indicating strong market demand and product performance.
- Product Performance: Recorlev® achieved net revenue of $45 million in Q4 2025 and $139 million for the full year, demonstrating increasing market acceptance in treating endogenous Cushing's syndrome.
- Patient Base Expansion: By the end of 2025, approximately 700 patients were on Recorlev® therapy, while Gvoke® saw revenue growth of over 13% year-over-year, showcasing the company's success in patient treatment and market penetration.
- Financial Stability: Xeris delivered positive adjusted EBITDA in every quarter, reinforcing the company's financial foundation and positioning it for sustained growth in the future.
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