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XERS Should I Buy

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Intellectia

Should You Buy Xeris Biopharma Holdings Inc (XERS) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Hold
Latest Price
5.470
1 Day change
3.40%
52 Week Range
10.080
Analysis Updated At
2026/03/20
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Xeris Biopharma Holdings Inc (XERS) is not a strong buy for a beginner investor with a long-term strategy at this time. While the company shows strong revenue growth, the negative net income, declining EPS, and bearish technical indicators suggest caution. Additionally, there are no significant positive catalysts or trading signals to support immediate action.

Technical Analysis

The stock is in a bearish trend with SMA_200 > SMA_20 > SMA_5. The MACD histogram is below 0 and negatively contracting, indicating weak momentum. RSI is neutral at 42.134, and the price is trading near the pivot level of 5.64. Key resistance is at 5.87, and support is at 5.411.

Options Data

Bullish
Open Interest Put-Call Ratio
Bullish
Option Volume Put-Call Ratio

The low put-call ratios indicate a bullish sentiment among options traders, but the overall volume is low, limiting its significance.

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
10
Buy
1

Positive Catalysts

  • Revenue increased by 37.06% YoY in Q3 2025, and gross margin improved by 16.60% YoY to 81.57%.

Neutral/Negative Catalysts

  • Net income dropped by -103.95% YoY, and EPS fell to 0, down -100% YoY. There are no recent news events or significant insider or hedge fund trading trends to act as catalysts. Technical indicators are bearish.

Financial Performance

In Q3 2025, revenue grew significantly to $74.38M (+37.06% YoY), but net income dropped to $621K (-103.95% YoY), and EPS fell to 0 (-100% YoY). Gross margin improved to 81.57% (+16.60% YoY).

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

No recent analyst rating or price target changes are available.

Wall Street analysts forecast XERS stock price to rise
4 Analyst Rating
Wall Street analysts forecast XERS stock price to rise
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 5.610
sliders
Low
9
Averages
9.67
High
10
Current: 5.610
sliders
Low
9
Averages
9.67
High
10
Barclays
Overweight
initiated
$9
AI Analysis
2025-12-08
Reason
Barclays
Price Target
$9
AI Analysis
2025-12-08
initiated
Overweight
Reason
Barclays initiated coverage of Xeris Biopharma with an Overweight rating and $9 price target. The firm rolled out coverage on the specialty pharmaceuticals industry with a neutral view, saying investor sentiment is improving as companies shift focus to innovation, margin expansion and de-leveraging. The group's pricing headwinds are easing while debt leverage is coming down, the analyst tells investors in a research note. Barclays sees "plenty of opportunity" as the sector "remains in a transition phase."
Piper Sandler
David Amsellem
Neutral
maintain
$6 -> $8
2025-11-07
Reason
Piper Sandler
David Amsellem
Price Target
$6 -> $8
2025-11-07
maintain
Neutral
Reason
Piper Sandler analyst David Amsellem raised the firm's price target on Xeris Biopharma to $8 from $6 and keeps a Neutral rating on the shares. The firm notes Xeris reported a Q3 net earnings per share of 0c on total revenues of $74.4M, compared to Street estimates of 1c and $74.2M, respectively. Notably, Recorlev continues to benefit from an expanding hypercortisolism space, positioning the company for sustainable cash generation, Piper adds.
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