Tech Analyst Kicks Off Coverage with Optimism; Check Out Thursday's Top 5 Initiations
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Aug 28 2025
0mins
Should l Buy GUTS?
Source: Benzinga
Analyst Coverage Initiations: Several Wall Street analysts have initiated coverage on various companies, providing ratings and price targets for their stocks.
Oddity Tech Ltd: Needham analyst Ryan MacDonald rated Oddity Tech Ltd (ODD) as a Buy with a price target of $72; shares closed at $60.48.
Acuren Corporation: Jefferies analyst Stephanie Moore also rated Acuren Corporation (TIC) as a Buy with a price target of $16, while shares closed at $10.60.
Other Companies: Analysts from BTIG, Ladenburg Thalmann, and Jefferies provided Neutral or Buy ratings for NANO Nuclear Energy Inc, Fractyl Health, Inc., and Biomea Fusion, Inc., respectively, with varying price targets.
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Analyst Views on GUTS
Wall Street analysts forecast GUTS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GUTS is 7.25 USD with a low forecast of 5.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Analyst Rating
4 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.425
Low
5.00
Averages
7.25
High
8.00
Current: 0.425
Low
5.00
Averages
7.25
High
8.00
About GUTS
Fractyl Health, Inc. is a metabolic therapeutics company. The Company is focused on developing new approaches to the treatment of metabolic diseases, including obesity and type 2 diabetes (T2D). The Company’s lead product candidate, Revita, is designed to remodel the duodenal lining via hydrothermal ablation (i.e. duodenal mucosal resurfacing) to reverse damage to intestinal nutrient sensing and signaling mechanisms caused by chronic high-fat and high-sugar diets that are a root cause of metabolic disease. The Revita clinical program is focused on patients living with obesity who want to maintain their weight loss after GLP-1 drug discontinuation. The Company’s Rejuva platform focuses on developing adeno-associated virus (AAV)-based, locally delivered gene therapies for the treatment of obesity and T2D. The Rejuva platform leverages advanced delivery systems and proprietary screening methods to identify and develop metabolically active gene therapy candidates targeting the pancreas.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Investigation Background: DJS Law Group is investigating Fractyl Health (NASDAQ: GUTS) for potential violations of securities laws, particularly whether the company issued misleading statements or failed to disclose material information to investors, indicating possible compliance risks.
- FDA Feedback Request: On January 29, 2026, Fractyl Health requested FDA feedback on potentially reclassifying Revita under the De Novo pathway instead of seeking Premarket Approval (PMA), which has drawn significant market attention.
- Stock Price Plunge: Following this news, shares of Fractyl Health fell by 67.48% in intraday trading on the same day, reflecting investor concerns about the company's future prospects and a sharp decline in market confidence.
- Commitment to Legal Services: DJS Law Group focuses on enhancing investor returns through balanced counseling and aggressive advocacy, dedicated to providing high-value litigation services for clients, particularly in securities class actions and corporate governance litigation.
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- Investigation Background: DJS Law Group is investigating Fractyl Health (NASDAQ: GUTS) for potential violations of securities laws, focusing on whether the company issued misleading statements or failed to disclose material information to investors.
- FDA Feedback Request: On January 29, 2026, Fractyl Health requested FDA feedback on potentially reclassifying Revita under the De Novo pathway instead of seeking Premarket Approval (PMA), drawing significant market attention.
- Stock Price Plunge: Following this news, shares of Fractyl Health fell by 67.48% in intraday trading on the same day, indicating substantial investor concern regarding the company's future prospects.
- Commitment to Legal Services: DJS Law Group is dedicated to enhancing investor returns through balanced counseling and aggressive advocacy, specializing in securities class actions and corporate governance litigation.
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- Stock Plunge: Fractyl Health's stock plummeted 64.81% to $0.644 on Thursday, hitting a 52-week low with a trading volume of 78.07 million shares, significantly exceeding the average of 3.31 million, indicating market concerns about the company's future.
- Regulatory Strategy Shift: The company plans to shift Revita's regulatory pathway from Premarket Approval (PMA) to the De Novo pathway, aiming for a more efficient approval process, with FDA feedback expected in Q2 2026, which could impact future market access.
- Clinical Trial Results: In the six-month randomized results from the REMAIN-1 Midpoint Cohort, Revita-treated patients experienced a 4.5% weight regain compared to 7.5% in the sham group, demonstrating significant weight maintenance effects that may enhance the product's market competitiveness.
- Safety Profile: Revita showed favorable safety and tolerability results over six months, with no treatment-emergent serious adverse events related to the device or procedure, which is crucial for future clinical promotion and market confidence.
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- Efficacy Data Release: Fractyl Health reported six-month data on its Revita endoscopic procedure, revealing a 4.5% weight regain in Revita patients compared to 7.5% in the placebo group, indicating the therapy's effectiveness in maintaining weight loss is below expectations.
- Exploratory Analysis Results: Among patients who achieved above-average weight loss on GLP-1 drugs, those receiving Revita experienced a 4.2% weight regain versus 13.3% in the placebo group, suggesting potential advantages for Revita in specific patient populations, although overall efficacy remains to be validated.
- Study Design Limitations: Fractyl noted that the midpoint cohort was not designed to be sufficiently powered for efficacy analysis, which may undermine the reliability of the results and lead to decreased market confidence in the company's future prospects.
- Future Outlook: The company plans to release one-year midpoint cohort results in Q3 and aims for an application submission in H2, presenting an opportunity to potentially restore market confidence despite the current disappointing data.
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- Clinical Trial Results: Fractyl Health's six-month data from the REMAIN-1 Midpoint Cohort indicates that Revita-treated participants regained only 4.5% of their weight compared to 7.5% in the sham group, highlighting the device's potential for weight maintenance.
- Lipid Improvements: Participants treated with Revita showed significant enhancements in lipid profiles, including increased HDL cholesterol and a lower triglyceride-to-HDL ratio, suggesting the device may influence metabolism through gut-mediated mechanisms.
- Patient Feedback: Patient-reported outcomes indicated reduced cravings for sweet foods among Revita-treated participants, further supporting the device's potential in appetite regulation and opening avenues for future market applications.
- Stock Volatility: Despite the positive study results, Fractyl Health's stock plummeted 63% in premarket trading, reflecting market concerns about the company's future prospects, although retail investor sentiment remains in 'extremely bullish' territory.
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- Market Performance: U.S. stocks opened mixed on Thursday, with the Dow Jones gaining approximately 0.1%, specifically up 0.05% to 49,042.28, while the NASDAQ fell 0.34% to 23,776.71, and the S&P 500 dipped 0.01% to 6,978.03, indicating a divergence in market sentiment.
- Sector Dynamics: Communication services shares rose by 2.5% on Thursday, contrasting with a 1.7% decline in information technology stocks, reflecting differing investor sentiments across sectors that could influence future capital flows.
- Tesla Investment: Tesla Inc. reported better-than-expected fourth-quarter results and announced plans to invest approximately $2 billion into CEO Elon Musk's AI startup, xAI, highlighting its strategic focus on AI development.
- Commodity Market: On Thursday, oil prices rose by 4.9% to $66.29, gold increased by 5.2% to $5,578.80, silver climbed 6.3% to $120.735, and copper surged 10.8% to $6.5645, indicating a strong rebound in the commodities market.
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