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BMEA Overview

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Intellectia

Loading chart...

High
1.390
Open
1.370
VWAP
1.36
Vol
1.31M
Mkt Cap
99.05M
Low
1.320
Amount
1.78M
EV/EBITDA(TTM)
--
Total Shares
72.30M
EV
43.24M
EV/OCF(TTM)
--
P/S(TTM)
--
Biomea Fusion, Inc. is a clinical-stage diabetes and obesity medicines company focused on the discovery and development of oral covalent small molecules to improve the lives of patients with diabetes, obesity, and metabolic diseases. A covalent small molecule is a synthetic compound that forms a permanent bond to its target protein. The Company has built its proprietary FUSION System discovery platform to advance a pipeline of small molecule product candidates. Its lead clinical program’s drug candidate, icovamenib, is being developed as an orally bioavailable, and selective covalent inhibitor of menin in two clinical and multiple preclinical studies, investigating icovamenib’s potential in type 1 and type 2 diabetes, as well as its impact in obesity. Its second product candidate BMF-650, is an investigational, oral small-molecule glucagon-like peptide-1 receptor agonists (GLP-1 RA), for the treatment of diabetes and obesity.
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Events Timeline

(ET)
2026-04-27
17:40:00
Biomea Fusion Announces Positive Results for Type 1 Diabetes Drug Trial
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2026-03-31 (ET)
2026-03-31
07:20:00
Biomea Fusion Initiates Phase II Trials for Icavamenib
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2026-03-15 (ET)
2026-03-15
10:50:00
Biomea Fusion Presents Positive Diabetes Study Results in Barcelona
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2026-01-12 (ET)
2026-01-12
08:40:00
Biomea Fusion Outlines Execution Priorities for 2026
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2025-12-09 (ET)
2025-12-09
20:10:00
Biomea Fusion Releases KOL Interview Discussing icovamenib Use in Diabetes Patients
select
2025-12-05 (ET)
2025-12-05
07:10:00
Biomea Fusion Presents COVALENT-111 Study Results at WCIRDC
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News

NASDAQ.COM
8.5
04-30NASDAQ.COM
Latest Developments in the Biotech Sector
  • Regulatory Approvals: Crinetics received European Commission approval for PALSONIFY to treat acromegaly in adults, becoming the first once-daily oral therapy in Europe, covering 27 EU member states, which is expected to significantly enhance market share.
  • Acquisition Expansion: Teva is acquiring Emalex Biosciences for $700 million, bolstering its neuroscience pipeline and potentially accelerating the NDA submission for Ecopipam, thereby strengthening Teva's competitive position in the CNS disorders market.
  • Clinical Trial Progress: Biomea Fusion's Icovamenib showed a 52% increase in mean C-peptide AUC in its Phase 2 trial for Type 1 Diabetes, indicating potential efficacy in early-stage patients, which may drive further development efforts.
  • Market Reactions: Despite multiple approvals, AstraZeneca and Novartis saw their stock prices decline by 0.79% and 1.76% respectively, reflecting a cautious investor sentiment towards the biotech sector.
NASDAQ.COM
9.0
04-28NASDAQ.COM
Biomea Fusion Reports Positive 52-Week Results for Icovamenib in Type 1 Diabetes Trial
  • Clinical Trial Results: Biomea Fusion's Phase 2 COVALENT-112 trial showed that Icovamenib 200 mg once daily led to a 52% increase in mean C-peptide AUC at 12 weeks in patients diagnosed with type 1 diabetes within the last 0-3 years, indicating significant improvement in endogenous insulin secretion.
  • Long-Term Efficacy: In patients with a longer disease duration of 3-15 years, C-peptide levels were generally preserved through Week 52, with only a modest decline of approximately 7%, demonstrating the drug's effectiveness and tolerability over an extended period.
  • Safety Profile: Throughout the 52-week observation period, Icovamenib was generally well tolerated, with no new or unexpected safety signals identified, enhancing its potential as a diabetes treatment option.
  • Future Research Plans: Biomea plans to initiate a new Phase 2 trial in the second half of 2026 to evaluate the effects of extended dosing of 200 mg on C-peptide levels and the potential benefits of adding an immunosuppressive agent to improve clinical outcomes.
Newsfilter
2.0
04-27Newsfilter
Biomea Fusion Reports Positive Results for Diabetes Treatment
  • Significant C-Peptide Increase: In patients diagnosed with diabetes within 0-3 years receiving 200 mg of icovamenib, a 52% increase in mean C-peptide AUC was observed at Week 12, indicating a substantial therapeutic effect and potential for improving insulin secretion.
  • Durability of Effect: The 200 mg group maintained a mean C-peptide AUC with only a 7% decline from baseline at Week 52, suggesting the treatment's lasting impact, which could offer new hope for diabetes patients.
  • Good Safety Profile: Icovamenib was generally well tolerated throughout the 52-week observation period, with no new safety signals identified, highlighting its potential as a short-course oral therapy that could transform diabetes treatment.
  • Future Research Plans: Biomea is planning a Phase 2 trial at four U.S. academic centers to evaluate the effects of extended dosing at 200 mg, further validating icovamenib's application in diabetes treatment.
seekingalpha
9.5
03-24seekingalpha
Biomea Fusion Reports FY 2025 Earnings Results
  • Earnings Highlights: Biomea Fusion reported a FY 2025 GAAP EPS of -$1.18, beating expectations by $0.36, indicating improvements in cost control and operational efficiency, although the company remains in a loss position.
  • Cash Position: As of December 31, 2025, the company had $56.2 million in cash, cash equivalents, and restricted cash, down from $58.6 million as of December 31, 2024, reflecting challenges in cash management.
  • Market Engagement: Biomea Fusion presented at several key conferences in 2026, including the International Conference on Advanced Technologies & Treatments for Diabetes, showcasing its active participation and technology promotion within the industry.
  • Investor Sentiment: Seeking Alpha's Quant Rating on Biomea Fusion indicates a cautious market outlook regarding its future performance, prompting investors to monitor the company's progress in R&D and market expansion.
Yahoo Finance
9.0
03-14Yahoo Finance
Biomea Fusion Reports Positive Results from Diabetes Study
  • Positive Study Results: Biomea Fusion presented 52-week follow-up results from its Phase II COVALENT-111 study at the ATTD conference in Barcelona, showing that icovamenib effectively reduced HbA1c levels in 267 patients, with a notable 1.2% reduction (p=0.01) in severe insulin-deficient patients, indicating the drug's potential in diabetes treatment.
  • Clinical Trial Design: The COVALENT-111 study utilized a double-blind, randomized, placebo-controlled design, enrolling adult patients diagnosed with type 2 diabetes within the last seven years, all of whom received lifestyle management at baseline, highlighting the clinical relevance of the drug in addressing unmet needs.
  • Favorable Safety Profile: Throughout the 52-week observation period, icovamenib maintained a favorable safety profile with no treatment-related serious adverse events or discontinuations due to adverse events, demonstrating good tolerability in diabetes patients.
  • Future Research Plans: Biomea Fusion anticipates releasing 52-week follow-up data from the COVALENT-112 study in type 1 diabetes patients in Q2 2026, along with 26-week primary endpoint data from the COVALENT-211 and COVALENT-212 studies expected in Q4 2026, further validating icovamenib's efficacy.
Globenewswire
1.0
2025-12-17Globenewswire
Biomea Fusion to Present at 44th Annual J.P. Morgan Healthcare Conference on January 14, 2026
  • Conference Presentation: Biomea Fusion's Interim CEO Dr. Mick Hitchcock will present at the 44th Annual J.P. Morgan Healthcare Conference on January 14, 2026, from 5:15 PM to 5:55 PM Pacific Time, aiming to enhance the company's visibility among investors and showcase its R&D progress.
  • One-on-One Meeting Opportunities: Throughout the conference, Biomea's management team will host one-on-one meetings, providing a platform for in-depth discussions with potential investors, thereby fostering stronger relationships and attracting more attention to the company.
  • Product Development Focus: Biomea Fusion is advancing oral small molecule therapies icovamenib and BMF-650 for diabetes and obesity, targeting metabolic disorders that affect nearly half of Americans and one-fifth of the global population, highlighting its strategic positioning in the biopharmaceutical sector.
  • Company Mission and Vision: Biomea's mission is to deliver transformative treatments for patients living with diabetes, obesity, and related conditions, aiming to improve patient health through innovative drug development, which underscores the company's significant role in addressing global health challenges.
Wall Street analysts forecast BMEA stock price to rise
5 Analyst Rating
Wall Street analysts forecast BMEA stock price to rise
4 Buy
0 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
4.00
Averages
7.75
High
12.00
Current: 0.000
sliders
Low
4.00
Averages
7.75
High
12.00
Citi
Buy
maintain
$6 -> $7
AI Analysis
2026-03-27
Reason
Citi
Price Target
$6 -> $7
AI Analysis
2026-03-27
maintain
Buy
Reason
Citi raised the firm's price target on Biomea Fusion to $7 from $6 and keeps a Buy rating on the shares. Citi also added an "upside 90-day catalyst watch" on Biomea. The firm sees investor interest increasing in company's oral GLP-1 candidate BMF-650 when it reports 28-day weight reduction data in healthy overweight or obese volunteers from the Phase 1 GLP-131 study in Q2.
JPMorgan
Neutral -> Underweight
downgrade
2025-11-15
Reason
JPMorgan
Price Target
2025-11-15
downgrade
Neutral -> Underweight
Reason
JPMorgan downgraded Biomea Fusion to Underweight from Neutral without a price target. The firm views the recent phase 2 COVALENT II icovamenib data in type 2 diabetes as "interesting" but has concerns around the company's ability to fund the ongoing and planned studies. The funding may come with significant dilution over the long-term without a partnership, which is difficult to predict, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Biomea Fusion Inc (BMEA.O) is 0.00, compared to its 5-year average forward P/E of -3.64. For a more detailed relative valuation and DCF analysis to assess Biomea Fusion Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.64
Current PE
0.00
Overvalued PE
-0.90
Undervalued PE
-6.37

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.16
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.92
Undervalued EV/EBITDA
-6.24

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

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Whales Holding BMEA

C
Cormorant Asset Management, LP
Holding
BMEA
-1.40%
3M Return

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Frequently Asked Questions

What is Biomea Fusion Inc (BMEA) stock price today?

The current price of BMEA is 1.37 USD — it has increased 0.74

What is Biomea Fusion Inc (BMEA)'s business?

Biomea Fusion, Inc. is a clinical-stage diabetes and obesity medicines company focused on the discovery and development of oral covalent small molecules to improve the lives of patients with diabetes, obesity, and metabolic diseases. A covalent small molecule is a synthetic compound that forms a permanent bond to its target protein. The Company has built its proprietary FUSION System discovery platform to advance a pipeline of small molecule product candidates. Its lead clinical program’s drug candidate, icovamenib, is being developed as an orally bioavailable, and selective covalent inhibitor of menin in two clinical and multiple preclinical studies, investigating icovamenib’s potential in type 1 and type 2 diabetes, as well as its impact in obesity. Its second product candidate BMF-650, is an investigational, oral small-molecule glucagon-like peptide-1 receptor agonists (GLP-1 RA), for the treatment of diabetes and obesity.

What is the price predicton of BMEA Stock?

Wall Street analysts forecast BMEA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for BMEA is7.75 USD with a low forecast of 4.00 USD and a high forecast of 12.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Biomea Fusion Inc (BMEA)'s revenue for the last quarter?

Biomea Fusion Inc revenue for the last quarter amounts to -11.72M USD, decreased -61.03

What is Biomea Fusion Inc (BMEA)'s earnings per share (EPS) for the last quarter?

Biomea Fusion Inc. EPS for the last quarter amounts to USD, decreased -100.00

How many employees does Biomea Fusion Inc (BMEA). have?

Biomea Fusion Inc (BMEA) has 41 emplpoyees as of May 03 2026.

What is Biomea Fusion Inc (BMEA) market cap?

Today BMEA has the market capitalization of 99.05M USD.