Short bets on S&P 500 Healthcare sector ease in May; MRNA stays most shorted stock
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Jun 13 2025
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Source: SeekingAlpha
Short Interest Trends: The S&P 500 Health Care Index saw a slight decrease in average short interest to 1.90% in May, with Moderna remaining the most heavily shorted stock at 19.23%, reflecting ongoing bearish sentiment due to declining vaccine sales and funding losses.
Sector Performance: The healthcare sector has underperformed the broader S&P 500 index, slipping 0.55% year-to-date, while biotechnology continues to be the most shorted industry within the sector, with an increase in short interest to 2.95%.
Analyst Views on XLV
Wall Street analysts forecast XLV stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for XLV is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
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Current: 158.260
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Current: 158.260
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About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.







