Acquisition Details: Pfizer has successfully acquired Metsera for $65.60 per share, totaling an enterprise value of approximately $7.0 billion, with potential additional payments based on clinical milestones.
Impact on Trading: Following the acquisition, Metsera's shares will cease trading on the NASDAQ Global Select Market, and the transaction is expected to be dilutive to Pfizer through 2030.
Strategic Importance: Pfizer views this acquisition as a significant investment in the future of medicine, focusing on high-growth therapeutic areas and enhancing its pipeline.
Leadership Statement: Pfizer's CEO, Albert Bourla, emphasized the goal of combining Metsera's innovative portfolio with Pfizer's infrastructure to accelerate the development of new therapies for patients globally.
Wall Street analysts forecast PFE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PFE is 29.08 USD with a low forecast of 24.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
15 Analyst Rating
Wall Street analysts forecast PFE stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PFE is 29.08 USD with a low forecast of 24.00 USD and a high forecast of 34.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
4 Buy
10 Hold
1 Sell
Hold
Current: 25.150
Low
24.00
Averages
29.08
High
34.00
Current: 25.150
Low
24.00
Averages
29.08
High
34.00
UBS
Neutral
initiated
$25
Al Analysis
2026-01-06
Reason
UBS
Price Target
$25
Al Analysis
2026-01-06
initiated
Neutral
Reason
UBS assumed coverage of Pfizer with a Neutral rating and $25 price target. The firm noted a backdrop of continued revenue uncertainty with $15B-$20B in revenues from key drugs losing patient exclusivity over the coming roughly three years. Though the firm is positive on the recent MTSR obesity deal, Pfizer needs to do more to offset 2028 LOE risk, the analyst tells investors in a research note.
BofA
Jason Gerberry
Neutral
downgrade
$28 -> $27
2025-12-16
Reason
BofA
Jason Gerberry
Price Target
$28 -> $27
2025-12-16
downgrade
Neutral
Reason
BofA analyst Jason Gerberry lowered the firm's price target on Pfizer to $27 from $28 and keeps a Neutral rating on the shares after the company "notably called out" faster COVID-19 product erosion relative to prior guidance as part of its 2026 outlook call. The firm, which "modestly" reduced its 2026 Pfizer sales and EPS estimates and its FY27 EPS estimate following the guidance call, looks to planned obesity data updates from the Metsera acquisition to better understand the company's potential obesity differentiation.
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BofA
Jason Gerberry
Neutral
downgrade
$29 -> $28
2025-12-15
Reason
BofA
Jason Gerberry
Price Target
$29 -> $28
2025-12-15
downgrade
Neutral
Reason
BofA analyst Jason Gerberry lowered the firm's price target on Pfizer to $28 from $29 and keeps a Neutral rating on the shares. The firm, which struggles to see a rerating catalyst as the company works through its multi-year loss of exclusivity period, is shifting its valuation basis to its FY27 EPS estimate.
Morgan Stanley
Equal Weight
downgrade
$32 -> $28
2025-12-12
Reason
Morgan Stanley
Price Target
$32 -> $28
2025-12-12
downgrade
Equal Weight
Reason
Morgan Stanley lowered the firm's price target on Pfizer to $28 from $32 and keeps an Equal Weight rating on the shares. The firm expects many of the policy overhangs that dominated the biopharma conversation this year to wane in 2026, bringing the focus back to fundamentals, the analyst tells investors in a 2026 outlook note for the group.
About PFE
Pfizer Inc. is a research-based, global biopharmaceutical company. The Company is engaged in the discovery, development, manufacture, marketing, sale and distribution of biopharmaceutical products worldwide. Its Biopharma segment includes the Pfizer U.S. Commercial Division, and the Pfizer International Commercial Division. Its product categories include oncology, primary care and specialty care. Its oncology products include Ibrance, Xtandi, Padcev, Adcetris, Inlyta, Lorbrena, Bosulif, Tukysa, Braftovi, Mektovi, Orgovyx, Elrexfio, Tivdak and Talzenna. Its primary care products include Eliquis, Nurtec ODT/Vydura, Zavzpret, the Prevnar family, Comirnaty, Abrysvo, FSME/IMMUN-TicoVac, Nimenrix, Trumenba, and Paxlovid. Its specialty care products include Xeljanz, Enbrel (outside the United States and Canada), Inflectra, Abrilada, Cibinqo, Litfulo, Eucrisa, Velsipity, the Vyndaqel family, Genotropin, BeneFIX, Xyntha, Somavert, Ngenla, Hympavzi, Sulperazon, Zavicefta, Octagam and others.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
