Lexeo Therapeutics Appoints New Executives, Strengthens Expertise in Cardiovascular Medicine
Lexeo Therapeutics announced a series of key senior leadership appointments that underscore the company's continued and growing expertise in cardiovascular medicine and late-stage clinical development. The company also provided an update on the strategic partnership announced in June 2025 with Perceptive Xontogeny Venture Funds and venBio Partners to develop therapies for genetic cardiac diseases utilizing a novel non-viral RNA platform. Narinder Bhalla, MD has been appointed Chief Medical Officer. Bhalla has held senior roles at AstraZeneca and, most recently, at Bristol Myers Squibb, where he served as Senior Vice President and Head of Global Medical, Immunology & Cardiovascular. In connection with Dr. Bhalla's appointment, Eric Adler, MD, currently Head of Research at Lexeo Therapeutics, will serve as President and CEO of cardiac precision medicines company, Myoventive, Inc. Lexeo co-founded Myoventive in June 2025 with Perceptive Xontogeny Venture Funds and venBio Partners, with subsequent participation by MRL Ventures Fund and Alexandria Venture Investments. Myoventive is utilizing a novel platform designed to enable targeted RNA modulation in the heart, addressing genetic cardiac diseases that existing AAV platforms are unable to treat. Dr. Adler will remain a senior clinical and scientific advisor to Lexeo.
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Lexeo Therapeutics Announces Key Senior Leadership Appointments
- Executive Appointments: Lexeo Therapeutics appoints Dr. Narinder Bhalla as Chief Medical Officer, leveraging over 20 years of experience in cardiovascular medicine and biopharma to drive innovation and development in cardiovascular disease treatments.
- Strategic Partnership Update: The collaboration with Perceptive Xontogeny Venture Funds and venBio Partners aims to develop therapies for genetic cardiac diseases using a novel non-viral RNA platform, reinforcing Lexeo's leadership in gene therapy.
- Operational Efficiency Boost: Dr. José Manuel Otero has been appointed Chief Operating Officer, focusing on enhancing Lexeo's operational efficiency and clinical supply capabilities while ensuring a smooth transition of manufacturing platforms under high regulatory standards.
- R&D Team Expansion: Newly appointed Dr. Hayes Dansky and Dr. Greg Aubert will lead late-stage and early-stage cardiology development, respectively, and their extensive R&D experience is expected to accelerate Lexeo's clinical progress in cardiovascular gene therapies.

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