
APLS
Apellis Pharmaceuticals Inc
- Overview
- Forecast
- Valuation
- Earnings

Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
20.3199
Open
19.950
VWAP
19.63
Vol
4.64M
Mkt Cap
2.52B
Low
19.160
Amount
90.99M
EV/EBITDA(TTM)
--
Total Shares
121.37M
EV
2.60B
EV/OCF(TTM)
--
P/S(TTM)
3.19
Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q4
FY2025Q3
FY2025Q2
217.94M
+2.55%
--
--
203.18M
+3.23%
--
--
190.36M
-4.67%
--
--
Estimates Revision
The market is revising Downward the revenue expectations for Apellis Pharmaceuticals, Inc. (APLS) for FY2025, with the revenue forecasts being adjusted by -10.69% over the past three months. During the same period, the stock price has changed by 14.54%.
Revenue Estimates for FY2025
Revise Downward

-10.69%
In Past 3 Month
Stock Price
Go Up

+14.54%
In Past 3 Month
18 Analyst Rating

77.75% Upside
Wall Street analysts forecast APLS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for APLS is 35.71 USD with a low forecast of 18.00 USD and a high forecast of 60.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
10 Buy
8 Hold
0 Sell
Moderate Buy

77.75% Upside
Current: 20.090

Low
18.00
Averages
35.71
High
60.00

77.75% Upside
Current: 20.090

Low
18.00
Averages
35.71
High
60.00
Baird
Colleen Kusy
maintain
$47 -> $50
2025-07-18
Reason
Baird
Colleen Kusy
Price Target
$47 -> $50
2025-07-18
maintain
Reason
Baird analyst Colleen Kusy raised the firm's price target on Apellis to $50 from $47 and keeps an Outperform rating on the shares. The firm updated its model ahead of Q2 earnings while noting a competitor's product to Syfovre is nearing C3G approval.
BofA
Neutral
maintain
$23 -> $24
2025-07-16
Reason
BofA
Price Target
$23 -> $24
2025-07-16
maintain
Neutral
Reason
BofA raised the firm's price target on Apellis to $24 from $23 and keeps a Neutral rating on the shares. Apellis has not provided sales guidance for Syfovre, which would provide more visibility on expectations for the Syfovre launch at this point, the analyst tells investors in a research note.
Morgan Stanley
Equal Weight
maintain
$25 -> $26
2025-07-02
Reason
Morgan Stanley
Price Target
$25 -> $26
2025-07-02
maintain
Equal Weight
Reason
Morgan Stanley raised the firm's price target on Apellis to $26 from $25 and keeps an Equal Weight rating on the shares. The royalty purchase agreement with Sobi bolsters Apellis' cash position, the analyst tells investors in a research note.
Wells Fargo
Equal Weight
maintain
$26 -> $29
2025-06-02
Reason
Wells Fargo
Price Target
$26 -> $29
2025-06-02
maintain
Equal Weight
Reason
Wells Fargo raised the firm's price target on Apellis to $29 from $26 and keeps an Equal Weight rating on the shares. The firm thinks Street's early estimates for the pegcetacoplan's launch in C3G/IC-MPGN may be conservative. That said, Wells awaits approval on the June 28 PDUFA and base biz stability before considering getting more constructive.
Wells Fargo
Derek Archila
Equal Weight
maintain
$26 -> $29
2025-06-02
Reason
Wells Fargo
Derek Archila
Price Target
$26 -> $29
2025-06-02
maintain
Equal Weight
Reason
Wells Fargo analyst Derek Archila raised the firm's price target on Apellis to $29 from $26 and keeps an Equal Weight rating on the shares.
Citi
Buy
downgrade
$49 -> $41
2025-05-22
Reason
Citi
Price Target
$49 -> $41
2025-05-22
downgrade
Buy
Reason
Citi lowered the firm's price target on Apellis to $41 from $49 and keeps a Buy rating on the shares following the Q1 report. The firm cut the price target to reflect a more gradual long-term ramp for Syfovre and Empaveli following the earnings report. Citi says its bull thesis is anchored on Empaveli's expected approval on or by July 28. It recommends adding to positions at current share levels.
See All Ratings
Valuation Metrics
The current forward P/E ratio for Apellis Pharmaceuticals Inc (APLS.O) is -17.95, compared to its 5-year average forward P/E of -19.64. For a more detailed relative valuation and DCF analysis to assess Apellis Pharmaceuticals Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
-19.64
Current PE
-17.95
Overvalued PE
-0.36
Undervalued PE
-38.93
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-20.50
Current EV/EBITDA
-25.32
Overvalued EV/EBITDA
104.47
Undervalued EV/EBITDA
-145.48
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

N/A
5Y Average PS
38.10
Current PS
2.79
Overvalued PS
91.14
Undervalued PS
-14.94
Financials
Annual
Quarterly
FY2025Q1
YoY :
-3.21%
166.80M
Total Revenue
FY2025Q1
YoY :
+34.21%
-83.33M
Operating Profit
FY2025Q1
YoY :
+38.84%
-92.23M
Net Income after Tax
FY2025Q1
YoY :
+37.04%
-0.74
EPS - Diluted
FY2025Q1
YoY :
-59.92%
-53.42M
Free Cash Flow
FY2025Q1
YoY :
-10.05%
79.40
Gross Profit Margin - %
FY2025Q1
YoY :
-98.97%
-1.08
FCF Margin - %
FY2025Q1
YoY :
+43.42%
-55.29
Net Margin - %
Trading Trends
Insider
Insiders areSelling! The selling amount has increased 3426.45% over the last month.
Sold
0-3
Months
3.4M
USD
5
3-6
Months
154.7K
USD
3
6-9
Months
2.8M
USD
41
0-12
Months
1.4M
USD
2
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds areBuying! The buying amount has increased 132.99% over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
473.5K
Volume
2
6-9
Months
1.2M
Volume
2
0-12
Months
0.0
Volume
0
Bought
0-3
1
2.0M
Volume
Months
3-6
2
858.4K
Volume
Months
6-9
5
4.3M
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders areSelling! The selling amount has increased 3426.45% over the last month.
Sold
0-3
Months
3.4M
USD
5
3-6
Months
154.7K
USD
3
6-9
Months
2.8M
USD
41
0-12
Months
1.4M
USD
2
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
APLS News & Events
Events Timeline
2025-07-01 (ET)
2025-07-01
07:04:24
Apellis to receive up to $300M from royalty purchase agreement with Sobi

2025-06-06 (ET)
2025-06-06
09:21:58
Apellis, Sobi present data from open-label period of Phase 3 VALIANT study

2025-05-07 (ET)
2025-05-07
07:03:23
Apellis expects cash be sufficient to fund operations to profitability

Sign Up For More Events
Sign Up For More Events
News
8.0
07-17NASDAQ.COMInteresting APLS Put And Call Options For September 19th
9.0
07-15NewsfilterApellis Announces Five Abstracts Accepted for Oral Presentation at the American Society of Retina Specialists (ASRS) Annual Scientific Meeting
6.5
07-08MarketWatchGoldman Sachs lifts S&P 500 forecasts, recommends these three investment moves
Sign Up For More News
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FAQ

What is Apellis Pharmaceuticals Inc (APLS) stock price today?
The current price of APLS is 20.09 USD — it has increased 0.95 % in the last trading day.

What is Apellis Pharmaceuticals Inc (APLS)'s business?

What is the price predicton of APLS Stock?

What is Apellis Pharmaceuticals Inc (APLS)'s revenue for the last quarter?

What is Apellis Pharmaceuticals Inc (APLS)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for Apellis Pharmaceuticals Inc (APLS)'s fundamentals?

How many employees does Apellis Pharmaceuticals Inc (APLS). have?
