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APLS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
40.930
Open
40.890
VWAP
40.90
Vol
3.11M
Mkt Cap
5.23B
Low
40.860
Amount
127.37M
EV/EBITDA(TTM)
91.56
Total Shares
127.84M
EV
5.22B
EV/OCF(TTM)
115.11
P/S(TTM)
5.18
Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom.
Show More

Events Timeline

(ET)
2026-04-01
05:40:00
Raymond James Downgrades Apellis to Market Perform
select

News

PRnewswire
7.0
04-14PRnewswire
Investor Rights Law Firm Investigates Multiple Companies
  • Investigation Focus: Halper Sadeh LLC is investigating companies such as Globalstar, Inc., Apellis Pharmaceuticals, Inc., and Forian Inc. for potential violations of federal securities laws and breaches of fiduciary duties, which may impact shareholder rights.
  • Transaction Details: Globalstar is being sold for $90 per share in cash or 0.3210 shares of Amazon stock, Apellis for $41 per share in cash plus two contingent value rights of $2 each, and Forian for $2.17 per share in cash, indicating varied transaction structures and associated risks.
  • Shareholder Rights Protection: The firm encourages shareholders to contact them to discuss their rights and options at no upfront cost, aiming to provide legal support for affected shareholders and ensure their interests are represented.
  • Legal Implications: The firm may seek increased consideration, additional disclosures, or other relief measures to protect shareholder rights, reflecting a commitment to corporate governance and transparency.
seekingalpha
8.5
04-14seekingalpha
Biogen Shares Rise After Upgrade and Acquisition Announcement
  • Stock Price Surge: Biogen (BIIB) shares rose after Piper Sandler upgraded the stock from Neutral to Overweight, raising the price target from $174 to $214, reflecting positive market sentiment regarding its acquisition of eye drug developer Apellis Pharmaceuticals (APLS).
  • Acquisition Deal: Biogen is set to complete the $5.6 billion acquisition of Apellis in Q2, which will enhance its Alzheimer's drug portfolio, with Apellis' Empaveli and Syfovre projected to generate $689 million in revenue by 2025, filling the revenue gap from the loss of exclusivity on its multiple sclerosis assets.
  • Portfolio Integration: Analysts noted that by integrating Empaveli with an advancing immunology pipeline, Biogen is positioned to achieve “meaningful top-line growth” in the future, helping to offset potential declines in royalties linked to the MS therapy Ocrevus.
  • Valuation Expansion Outlook: Piper analysts anticipate that Biogen's EV/2026E EBITDA multiple will expand from approximately 11x to 13x, indicating optimistic investor sentiment regarding the company's future growth potential and reflecting confidence in its profitability trajectory.
PRnewswire
7.0
04-10PRnewswire
Investor Rights Law Firm Investigates Multiple Companies
  • Legal Investigation Launched: Halper Sadeh LLC is investigating Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) regarding its sale to Biogen Inc. for $41.00 per share in cash and two contingent value rights of $2.00 each, potentially infringing on shareholder rights.
  • Shareholder Rights Protection: The firm encourages Apellis shareholders to understand their legal rights and options, emphasizing free consultations to ensure that shareholder interests are protected in the transaction.
  • Additional Company Investigations: Centessa Pharmaceuticals plc (NASDAQ:CNTA) is also under scrutiny for its sale to Eli Lilly for $38.00 per share plus a contingent value right of up to $9.00, with Halper Sadeh LLC investigating possible breaches of fiduciary duties.
  • Legal Relief Measures: Halper Sadeh LLC represents investors globally, seeking increased consideration, additional disclosures, or other relief to advocate for the rights of affected shareholders.
PRnewswire
7.0
04-07PRnewswire
Investor Rights Law Firm Investigates Multiple Companies for Potential Violations
  • Investigation Background: Halper Sadeh LLC is investigating companies like Apellis Pharmaceuticals, KORE Group Holdings, and Centessa Pharmaceuticals for potential violations of federal securities laws and breaches of fiduciary duties, which may impact shareholder rights.
  • Apellis Transaction Details: Apellis Pharmaceuticals is being sold to Biogen Inc. for $41.00 per share in cash, along with a non-transferable right to receive two payments of $2.00 each, contingent on meeting specific global net sales thresholds, potentially affecting shareholder returns.
  • KORE Transaction Situation: KORE Group Holdings is being sold for $9.25 per share to Searchlight Capital Partners and Abry Partners, prompting shareholders to consider the implications of this transaction on their rights and available legal options.
  • Centessa Transaction Analysis: Centessa Pharmaceuticals is being sold for $38.00 per share in cash, plus a non-transferable right entitling holders to receive up to $9.00 upon achieving certain milestones, urging shareholders to understand their legal rights and options.
Globenewswire
8.5
04-07Globenewswire
Monteverde Law Firm Investigates Multiple Acquisition Cases
  • Shareholder Compensation Investigation: Monteverde Law Firm is investigating the transaction between Affinity Bancshares, Inc. and Fidelity Bancshares, where Affinity shareholders are expected to receive $23.00 per share in cash, significantly impacting shareholder returns.
  • Apellis Pharmaceutical Deal: In the transaction between Apellis Pharmaceuticals, Inc. and Biogen, Apellis shareholders are expected to receive $41.00 per share in cash along with two non-transferable rights of $2.00 each, providing additional potential earnings and enhancing investment appeal.
  • Olaplex Acquisition Case: In the deal between Olaplex Holdings, Inc. and Henkel US Operations, Olaplex shareholders are expected to receive $2.06 per share in cash, offering direct cash returns to shareholders and boosting market confidence.
  • KORE Group Transaction: In the transaction involving KORE Group Holdings, Inc. and Searchlight Capital Partners, KORE shareholders are expected to receive $9.25 per share in cash, providing substantial cash flow to shareholders and further solidifying their market position.
Globenewswire
7.0
04-07Globenewswire
Ademi LLP Investigates Apellis for Potential Fiduciary Breaches in Biogen Deal
  • Investigation Launched: Ademi LLP is investigating Apellis for potential breaches of fiduciary duty in its transaction with Biogen, highlighting concerns over corporate governance that may impact shareholder confidence.
  • Transaction Details: In this deal, Apellis shareholders will receive $41 per share in cash plus contingent value rights, with an additional $2 per share if SYFOVRE achieves $1.5 billion in annual sales from 2027 to 2030, indicating potential upside for investors.
  • Sales Target Incentives: Should SYFOVRE reach $2 billion in sales in 2031, shareholders would receive an additional $4 per share, creating a performance-driven structure that could attract investor interest but also increases pressure on sales targets.
  • Competition Restriction Clause: The transaction agreement imposes significant penalties for accepting competing bids, which may limit Apellis's strategic flexibility in the future, raising red flags for shareholders regarding governance and decision-making processes.
Wall Street analysts forecast APLS stock price to rise
14 Analyst Rating
Wall Street analysts forecast APLS stock price to rise
9 Buy
5 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
19.00
Averages
31.69
High
48.00
Current: 0.000
sliders
Low
19.00
Averages
31.69
High
48.00
Wells Fargo
Derek Archila
Overweight -> Equal Weight
downgrade
$26 -> $41
AI Analysis
2026-04-17
New
Reason
Wells Fargo
Derek Archila
Price Target
$26 -> $41
AI Analysis
2026-04-17
New
downgrade
Overweight -> Equal Weight
Reason
As previously reported, Wells Fargo analyst Derek Archila downgraded Apellis (APLS) to Equal Weight from Overweight with a price target of $41, up from $26. The firm is moving to the sidelines following Biogen's (BIIB) announced acquisition of the company. Wells expects the deal to close in Q2 2026.
Wells Fargo
Overweight -> Equal Weight
downgrade
$26 -> $41
2026-04-17
New
Reason
Wells Fargo
Price Target
$26 -> $41
2026-04-17
New
downgrade
Overweight -> Equal Weight
Reason
Wells Fargo downgraded Apellis to Equal Weight from Overweight with a price target of $41, up from $26.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for APLS
Unlock Now

Valuation Metrics

The current forward P/E ratio for Apellis Pharmaceuticals Inc (APLS.O) is 46.30, compared to its 5-year average forward P/E of -24.22. For a more detailed relative valuation and DCF analysis to assess Apellis Pharmaceuticals Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-24.22
Current PE
46.30
Overvalued PE
11.89
Undervalued PE
-60.33

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-17.58
Current EV/EBITDA
-19.93
Overvalued EV/EBITDA
112.42
Undervalued EV/EBITDA
-147.58

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
23.40
Current PS
5.08
Overvalued PS
46.97
Undervalued PS
-0.18

Financials

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Whales Holding APLS

T
The Morningside Group Limited
Holding
APLS
+31.65%
3M Return
A
Artal Group S.A.
Holding
APLS
+19.34%
3M Return
A
Avoro Capital Advisors LLC
Holding
APLS
+14.87%
3M Return
S
Suvretta Capital Management, LLC
Holding
APLS
+11.13%
3M Return
K
Kynam Capital Management, LP
Holding
APLS
+8.04%
3M Return
O
OrbiMed Advisors LLC
Holding
APLS
+2.04%
3M Return

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Frequently Asked Questions

What is Apellis Pharmaceuticals Inc (APLS) stock price today?

The current price of APLS is 40.915 USD — it has increased 0.04

What is Apellis Pharmaceuticals Inc (APLS)'s business?

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom.

What is the price predicton of APLS Stock?

Wall Street analysts forecast APLS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for APLS is31.69 USD with a low forecast of 19.00 USD and a high forecast of 48.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Apellis Pharmaceuticals Inc (APLS)'s revenue for the last quarter?

Apellis Pharmaceuticals Inc revenue for the last quarter amounts to 199.91M USD, decreased -5.94

What is Apellis Pharmaceuticals Inc (APLS)'s earnings per share (EPS) for the last quarter?

Apellis Pharmaceuticals Inc. EPS for the last quarter amounts to -0.47 USD, increased 62.07

How many employees does Apellis Pharmaceuticals Inc (APLS). have?

Apellis Pharmaceuticals Inc (APLS) has 733 emplpoyees as of April 20 2026.

What is Apellis Pharmaceuticals Inc (APLS) market cap?

Today APLS has the market capitalization of 5.23B USD.