The chart below shows how APLS performed 10 days before and after its earnings report, based on data from the past quarters. Typically, APLS sees a +13.24% change in stock price 10 days leading up to the earnings, and a +3.21% change 10 days following the report. On the earnings day itself, the stock moves by -4.54%. This data can give you a slight idea of what to expect for the next quarter's release.
Positive
Impressive Revenue Surge: 1. Strong Revenue Growth: Apellis reported total revenue of approximately $197 million for Q3 2024, a significant increase from $110 million in the same quarter last year, showcasing strong year-over-year growth.
SYFOVRE Demand Surge: 2. Increased Demand for SYFOVRE: Commercial vial demand for SYFOVRE grew by 7% quarter-over-quarter, with 84,500 commercial vials shipped to physicians, reinforcing its market leadership.
High Compliance in Treatment: 3. High Compliance Rate for EMPAVELI: EMPAVELI generated $24.6 million in U.S. product revenue in PNH during Q3 2024, with a remarkable compliance rate of 97%, indicating strong patient adherence to treatment.
VALIANT Study Success: 4. Positive Phase III VALIANT Results: The Phase III VALIANT study results for EMPAVELI in C3G and IC-MPGN demonstrated a statistically significant 68% reduction in proteinuria, highlighting its potential as a best-in-class treatment.
Cash Reserves Strength: 5. Strong Cash Position: Apellis ended Q3 2024 with $397 million in cash and cash equivalents, providing a solid financial foundation to support ongoing operations and future growth initiatives.
Negative
Quarterly Revenue Decline: 1. Revenue Decline: SYFOVRE's net product revenue fell by 1.7% compared to the previous quarter, despite a year-over-year increase of over 100%.
Gross to Net Adjustments: 2. Increased Gross to Net Adjustments: The company experienced higher gross to net adjustments due to strategic contracting decisions, impacting overall net revenue and leading to a significant increase in SYFOVRE's gross to net percentage this quarter.
Flat Revenue Growth Outlook: 3. Flat Revenue Growth Guidance: Apellis anticipates flat to modest net revenue growth in the fourth quarter of 2024, indicating a slowdown in sales momentum.
CHMP Negative Opinion Impact: 4. Negative CHMP Opinion: The company received a negative opinion from the CHMP regarding SYFOVRE, leading to a halt in pursuing EU approval, which could limit market expansion.
Quarterly Net Loss: 5. Net Loss: Apellis reported a net loss of $57.4 million for the third quarter, reflecting ongoing financial challenges despite revenue growth.
Apellis Pharmaceuticals, Inc. (APLS) Q3 2024 Earnings Call Transcript
APLS.O
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