Cyclerion Announces Exclusive Collaboration with Medsteer
Cyclerion Therapeutics announced an application-specific, exclusive collaboration with Medsteer. The new collaboration agreement expands upon the parties' existing development collaboration and is intended to enable the integration of Medsteer's technology and know-how into Cyclerion's lead program, CYC-126. CYC-126 is an anesthetic-based investigational therapy that incorporates real-time patient feedback and is currently being developed for the treatment of treatment-resistant depression. Cyclerion remains on track to complete device integration and finalize its proprietary drug delivery system ahead of the planned initiation of the Phase 2 POC study of CYC-126 in the second half of 2026. The company expects to leverage primarily FDA-cleared device components, together with the Medsteer strategic partnership and the previously announced MIT license, with the company's own fit-for-purpose improvements, to support full device build prior to the Phase 2 POC start this year.
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