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CYCN Overview

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Intellectia

Loading chart...

High
1.590
Open
1.530
VWAP
1.54
Vol
61.63K
Mkt Cap
6.24M
Low
1.440
Amount
94.91K
EV/EBITDA(TTM)
--
Total Shares
3.93M
EV
1.67M
EV/OCF(TTM)
--
P/S(TTM)
1.59
Cyclerion Therapeutics, Inc. is a biopharmaceutical company dedicated to identifying, developing, and delivering therapies for central nervous system (CNS) diseases. The Company is focused on building a pipeline with therapeutics to treat certain neuropsychiatric diseases. It is focused on an individualized therapy for treatment-resistant depression (TRD) - a condition with significant unmet medical need. Its assets include Olinciguat and Praliciguat. The Company has entered into an exclusive license option agreement for its vascular soluble guanylate cyclase (sGC) stimulator, olinciguat. Praliciguat is an oral, once-daily, systemic sGC stimulator that is licensed to Akeibia Therapeutics, Inc and is being advanced in rare kidney disease.
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Events Timeline

(ET)
2026-02-17
07:20:00
Cyclerion Receives Positive FDA Feedback on CYC-126
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2026-01-05 (ET)
2026-01-05
16:10:00
Cyclerion Announces Exclusive Collaboration with Medsteer
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2025-12-22 (ET)
2025-12-22
16:50:00
Cycurion Files to Sell 4.97M Shares of Common Stock for Holders
select
2025-09-23 (ET)
2025-09-23
16:08:20
Cyclerion Signs Licensing Deal with MIT and Unveils Strategic Relaunch
select
2025-05-06 (ET)
2025-05-06
16:59:34
Cyclerion Therapeutics files to sell 500K shares of common stock for holders
select
2024-12-17 (ET)
2024-12-17
07:20:51
Cyclerion Therapeutics announces update on next stage of growth
select

News

Newsfilter
8.5
02-17Newsfilter
Cyclerion Receives Positive FDA Feedback, Advancing CYC-126 Study
  • Positive FDA Feedback: Cyclerion has received encouraging written feedback from the FDA regarding CYC-126, clarifying its clinical development pathway for treatment-resistant depression (TRD), with plans to initiate the Phase 2 proof-of-concept study in the second half of 2026, marking a significant advancement in the company's drug development efforts.
  • Personalized Treatment Strategy: CYC-126 integrates real-time electroencephalogram (EEG) feedback with individualized anesthetic dosing, aiming to precisely guide patients to brain states associated with antidepressant effects, addressing the urgent need for new therapies among TRD patients and presenting substantial market potential.
  • Clinical Advisory Board Formation: Cyclerion has established a Clinical Advisory Board, appointing five internationally recognized experts in neuropsychiatry and anesthesiology to provide strategic guidance, ensuring that the clinical development of CYC-126 adheres to the highest scientific standards while expanding the company's pipeline in neuropsychiatric diseases.
  • Multinational Study Plans: The company has selected a contract research organization to support the execution of the planned multinational study, ensuring the initiation of the Phase 2 study of CYC-126 in the second half of 2026, further solidifying its market position in the treatment of neuropsychiatric disorders.
Benzinga
9.5
01-08Benzinga
AZZ Inc Reports Q3 Earnings Beat, Shares Rise 2.1%
  • Earnings Beat: AZZ Inc reported adjusted earnings of $1.52 per share for Q3, surpassing market expectations of $1.47, indicating sustained profitability that may attract more investor interest.
  • Sales Growth: The company achieved sales of $425.746 million, exceeding expectations of $418.164 million, demonstrating strong market demand and further solidifying its position in the industry.
  • Stock Price Surge: In pre-market trading, AZZ Inc shares rose 2.1% to $112.09, reflecting a positive market reaction to its earnings report, which could boost investor confidence in subsequent trading days.
  • Optimistic Market Outlook: With improved performance, AZZ Inc is poised to continue attracting investment and enhancing its competitive edge, particularly in the context of the current economic recovery.
Benzinga
9.0
01-06Benzinga
Alumis Inc. Shares Surge 132% After Successful Phase 3 Trial Results
  • Trial Success: Alumis Inc. achieved all primary and secondary endpoints in its Phase 3 ONWARD1 and ONWARD2 trials for envudeucitinib in moderate-to-severe plaque psoriasis, resulting in a 132% surge in stock price, indicating strong market potential and investor confidence.
  • Market Reaction: Following the announcement, shares skyrocketed to $19.30, reflecting a positive investor response to the clinical data, which may attract more institutional investors and further enhance the company's market capitalization.
  • Industry Impact: Alumis's success provides a new treatment option in the biopharmaceutical industry, particularly in the psoriasis sector, potentially prompting other companies to increase R&D investments and drive overall industry innovation.
  • Future Outlook: With the successful clinical trials, Alumis is expected to accelerate the drug's market entry, likely leading to significant revenue growth while strengthening its position in the highly competitive biopharmaceutical market.
Benzinga
9.5
01-06Benzinga
AngioDynamics Surpasses Expectations with $79.4M Sales and Break-Even EPS
  • Earnings Beat: AngioDynamics reported an adjusted EPS of $0.00 for Q2, exceeding market expectations of a 10-cent loss, indicating a significant improvement in the company's profitability.
  • Sales Growth: The company achieved sales of $79.4 million, surpassing the market forecast of $76.3 million, demonstrating strong product demand and driving overall performance enhancement.
  • Positive Market Reaction: Following the earnings release, AngioDynamics' stock received favorable attention from investors, reflecting confidence in its future growth potential, which may further drive stock price appreciation.
  • Optimistic Industry Outlook: With the recovery of the medical device sector, AngioDynamics' robust performance could attract more investor interest, strengthening its position in a competitive market.
NASDAQ.COM
7.5
01-06NASDAQ.COM
Cyclerion (CYCN) Enters Exclusive Collaboration with Medsteer to Advance CYC-126 Clinical Trials
  • Exclusive Collaboration Agreement: Cyclerion Therapeutics has signed an application-specific exclusive collaboration with Medsteer, aiming to integrate Medsteer's closed-loop anesthetic delivery systems with Cyclerion's CYC-126 program, thereby enhancing clinical development efficiency for treatment-resistant depression.
  • Clinical Trial Plans: Cyclerion plans to initiate a Phase 2 Proof of Concept clinical trial for CYC-126 in the second half of 2026, which is expected to provide personalized treatment for approximately 3 million Americans suffering from treatment-resistant depression, significantly improving patient quality of life.
  • Positive Market Reaction: Following the announcement of the collaboration, CYCN's stock surged 47.10% in premarket trading to $2.03, reflecting strong market recognition of the collaboration's potential, which may drive future financing and growth for the company.
  • Technology Integration Progress: Cyclerion will leverage its neuropsychiatric and clinical development expertise to strengthen the integration with Medsteer's technology, with device integration expected to be completed in 2026, laying a solid foundation for subsequent clinical trials.
Benzinga
7.5
01-06Benzinga
Cyclerion Therapeutics Expands Collaboration with Medsteer, Shares Surge 44.2%
  • Significant Stock Surge: Cyclerion Therapeutics shares rose 44.2% to $1.99 in pre-market trading, reflecting strong market confidence in the company's expanded strategic collaboration with Medsteer, indicating positive investor sentiment towards future growth prospects.
  • Deepening Strategic Collaboration: The partnership with Medsteer aims to advance the closed-loop anesthetic platform CYC-126, which is expected to accelerate the product's market entry, thereby enhancing the company's competitive edge in the anesthesia sector.
  • Optimistic Market Outlook: With continuous advancements in anesthetic technology, Cyclerion's new platform is poised to meet the increasing medical demand, further driving revenue growth and strengthening its position in the healthcare industry.
  • Increased Investor Confidence: The substantial stock price increase not only reflects market approval of the company's strategic direction but may also attract more investor interest, thereby supporting future financing and expansion efforts.

Valuation Metrics

The current forward P/E ratio for Cyclerion Therapeutics Inc (CYCN.O) is -0.04, compared to its 5-year average forward P/E of -0.62. For a more detailed relative valuation and DCF analysis to assess Cyclerion Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.62
Current PE
-0.04
Overvalued PE
0.17
Undervalued PE
-1.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.09
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.29
Undervalued EV/EBITDA
-0.46

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
8.35
Current PS
2.50
Overvalued PS
21.48
Undervalued PS
-4.77

Financials

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Frequently Asked Questions

What is Cyclerion Therapeutics Inc (CYCN) stock price today?

The current price of CYCN is 1.59 USD — it has increased 5.3

What is Cyclerion Therapeutics Inc (CYCN)'s business?

Cyclerion Therapeutics, Inc. is a biopharmaceutical company dedicated to identifying, developing, and delivering therapies for central nervous system (CNS) diseases. The Company is focused on building a pipeline with therapeutics to treat certain neuropsychiatric diseases. It is focused on an individualized therapy for treatment-resistant depression (TRD) - a condition with significant unmet medical need. Its assets include Olinciguat and Praliciguat. The Company has entered into an exclusive license option agreement for its vascular soluble guanylate cyclase (sGC) stimulator, olinciguat. Praliciguat is an oral, once-daily, systemic sGC stimulator that is licensed to Akeibia Therapeutics, Inc and is being advanced in rare kidney disease.

What is the price predicton of CYCN Stock?

Wall Street analysts forecast CYCN stock price to fall over the next 12 months. According to Wall Street analysts, the average 1-year price target for CYCN is USD with a low forecast of USD and a high forecast of USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Cyclerion Therapeutics Inc (CYCN)'s revenue for the last quarter?

Cyclerion Therapeutics Inc revenue for the last quarter amounts to 875.00K USD, increased 351.03

What is Cyclerion Therapeutics Inc (CYCN)'s earnings per share (EPS) for the last quarter?

Cyclerion Therapeutics Inc. EPS for the last quarter amounts to -0.30 USD, increased 3.45

How many employees does Cyclerion Therapeutics Inc (CYCN). have?

Cyclerion Therapeutics Inc (CYCN) has 1 emplpoyees as of March 21 2026.

What is Cyclerion Therapeutics Inc (CYCN) market cap?

Today CYCN has the market capitalization of 6.24M USD.