Sutro Biopharma Approves 1-for-10 Reverse Stock Split to Meet Nasdaq Compliance
Written by Emily J. Thompson, Senior Investment Analyst
Updated: Dec 01 2025
0mins
Should l Buy STRO?
Source: Globenewswire
- Reverse Stock Split Decision: Sutro Biopharma's Board has approved a 1-for-10 reverse stock split aimed at regaining compliance with Nasdaq's minimum bid price requirement of $1.00 per share, thereby ensuring continued listing eligibility.
- Shareholder Meeting Support: The reverse stock split plan was approved at the annual shareholder meeting on June 6, 2025, reflecting shareholder confidence in the company's governance and future development.
- Share Count Adjustment: Post-split, Sutro's outstanding shares will decrease from approximately 85.2 million to about 8.5 million, impacting all shareholders uniformly while maintaining their percentage ownership interests.
- Trading Symbol Remains Unchanged: The reverse stock split will take effect on December 3, 2025, with Sutro's stock continuing to trade under the symbol “STRO”, ensuring market recognition and liquidity are not adversely affected.
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Analyst Views on STRO
Wall Street analysts forecast STRO stock price to rise
7 Analyst Rating
4 Buy
2 Hold
1 Sell
Moderate Buy
Current: 15.620
Low
8.00
Averages
20.00
High
51.00
Current: 15.620
Low
8.00
Averages
20.00
High
51.00
About STRO
Sutro Biopharma, Inc. is an oncology company engaged in developing site-specific and novel-format antibody drug conjugates (ADCs), enabled by its proprietary integrated cell-free protein synthesis platform, XpressCF, and its site-specific conjugation platform, XpressCF+. It designs and develops therapeutics using the relevant and potent modalities, including ADCs, bispecific ADCs, immunostimulatory ADCs, and dual conjugate ADCs. Enabled through its XpressCF and XpressCF+ platforms, it has entered multi-target, product-focused collaborations with pharmaceutical and biotechnology companies in the field of oncology, with its ongoing relationships that include licensing to Ipsen, on an exclusive basis, the right to research, develop, manufacture and commercialize STRO-003. STRO-003 is developed for the treatment of solid tumors. Its XpressCF and XpressCF platforms supports Vaxcyte, focused on discovery and development of vaccines for the treatment and prophylaxis of infectious disease.
About the author
Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
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- Use of Proceeds: The net proceeds from this offering will be used alongside existing cash primarily for general corporate purposes, including R&D, clinical development, manufacturing, working capital, and potential acquisitions or investments, aimed at advancing the company's strategic objectives.
- Market Reaction: Following the announcement of the offering, Sutro Biopharma's shares rose 4.5% in premarket trading, reflecting a positive market response to the company's financing plans, which may bolster investor confidence.
- Future Outlook: The closing of this stock offering is expected around February 11, 2026, marking a strategic reset for Sutro in its next-generation ADC pipeline and platform innovation, potentially opening new avenues for growth.
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- Technological Platform: Sutro's next-generation ADC platform aims to deliver single- and dual-payload ADCs by optimizing antibodies, linkers, and payloads, designed to improve drug exposure, reduce side effects, and expand treatable tumor types, demonstrating the company's technological edge in cancer therapy.
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- Treatment Protocol Optimization: The therapy follows a continuous infusion schedule structured as two-week treatment periods followed by two-week rest intervals, which is expected to improve patient adherence and treatment outcomes over a four-month duration.
- Market Potential: Targeting CD33-positive acute myeloid leukemia and high-risk myelodysplastic syndrome, GTB-3650 represents a significant complement to traditional therapies, potentially unlocking substantial market opportunities for the company.
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See More
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- Reverse Split Impact: The company's 1:10 reverse stock split effective December 3, 2025, aimed to elevate its share price and attract more investors, with the subsequent recovery in stock price reflecting market confidence in its future growth prospects.
- Market Outlook: Sutro focuses on developing antibody-drug conjugates (ADCs) with a unique dual-payload platform that aims to address treatment resistance in cancer therapies, catering to the significant demand for new therapies in large oncology markets, thereby driving business growth.
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See More
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- Reverse Split Impact: The company executed a 1:10 reverse stock split on December 3, 2025, which not only elevated the stock price but also ensured that it no longer fell below Nasdaq's minimum bid requirement, thereby boosting investor confidence.
- Market Outlook: Sutro focuses on developing next-generation antibody-drug conjugates (ADCs), with its unique dual-payload platform aimed at overcoming treatment resistance in cancer therapy, indicating significant market demand and strategic growth potential for the company.
- Investor Interest: The company's innovative capabilities in biotechnology and compliance restoration are likely to attract more investor attention, potentially driving further stock price increases and enhancing market confidence in its product pipeline.
See More
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- Use of Proceeds: The net proceeds from this offering will be used alongside existing cash primarily for general corporate purposes, including R&D, clinical development, manufacturing, working capital, and potential acquisitions or investments, aimed at advancing the company's strategic objectives.
- Market Reaction: Following the announcement of the offering, Sutro Biopharma's shares rose 4.5% in premarket trading, reflecting a positive market response to the company's financing plans, which may bolster investor confidence.
- Future Outlook: The closing of this stock offering is expected around February 11, 2026, marking a strategic reset for Sutro in its next-generation ADC pipeline and platform innovation, potentially opening new avenues for growth.
See More
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- Conference Appearance: Sutro Biopharma CEO Jane Chung will present at the 44th J.P. Morgan Healthcare Conference on January 15, 2026, at 11:15 AM PT in San Francisco, showcasing the company's innovations in antibody-drug conjugates (ADCs), which is expected to attract investor interest and enhance the company's visibility.
- Live Webcast: The presentation will be accessible via a live webcast on the company's Investor Relations page, with an archived replay available for at least 30 days post-event, ensuring that investors unable to attend can still access key information, thereby enhancing investor engagement and trust.
- Technological Platform: Sutro's next-generation ADC platform aims to deliver single- and dual-payload ADCs by optimizing antibodies, linkers, and payloads, designed to improve drug exposure, reduce side effects, and expand treatable tumor types, demonstrating the company's technological edge in cancer therapy.
- Market Potential: Sutro's ADC pipeline targets large oncology markets with limited treatment options and significant need for improved therapies, indicating the company's strategic positioning to meet unmet medical needs in the oncology sector.
See More
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- Clinical Advancement: GT Biopharma has advanced its GTB-3650 clinical trial to Cohort 4, where patients are receiving a dosing of 10μg/kg/day, indicating potential efficacy against resistant blood cancers, with further results expected in Q1 2026.
- Safety Confirmation: Six patients across Cohorts 1, 2, and 3 have successfully completed treatment with GTB-3650, establishing the therapy's safety profile at escalating doses without any dose-limiting toxicities, thereby enhancing confidence in the clinical trial.
- Dose Escalation Plan: The trial is designed to include seven cohorts, with plans to enroll two patients per cohort, escalating doses from 1.25μg/kg/day to potentially 100μg/kg/day, demonstrating the company's ongoing commitment to efficacy and patient care.
- Therapeutic Prospects: GT Biopharma is also advancing GTB-5550, with regulatory submission for human trials expected in late December 2025 or January 2026, further expanding its market opportunities in cancer treatment.
See More
GT Biopharma Advances GTB-3650 Clinical Trial to Cohort 4 with 10μg/kg/day Dosing
- Clinical Trial Progress: GT Biopharma has advanced its GTB-3650 clinical trial to Cohort 4, where patients are receiving a dosing of 10μg/kg/day, indicating enhanced safety and potential efficacy in combating resistant blood cancers.
- Treatment Protocol Optimization: The therapy follows a continuous infusion schedule structured as two-week treatment periods followed by two-week rest intervals, which is expected to improve patient adherence and treatment outcomes over a four-month duration.
- Market Potential: Targeting CD33-positive acute myeloid leukemia and high-risk myelodysplastic syndrome, GTB-3650 represents a significant complement to traditional therapies, potentially unlocking substantial market opportunities for the company.
- Future Outlook: The company plans to share its next trial update in Q1 2026, and as dosing escalates, GTB-3650 is expected to approach higher efficacy ranges, further advancing its clinical development trajectory.
See More
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- Compliance Restoration: Sutro Biopharma's common stock achieved an average closing price of $1.00 as of December 16, 2025, successfully regaining compliance with Nasdaq listing standards, thereby mitigating risks associated with potential delisting and ensuring continued access to capital markets.
- Reverse Split Impact: The company's 1:10 reverse stock split effective December 3, 2025, aimed to elevate its share price and attract more investors, with the subsequent recovery in stock price reflecting market confidence in its future growth prospects.
- Market Outlook: Sutro focuses on developing antibody-drug conjugates (ADCs) with a unique dual-payload platform that aims to address treatment resistance in cancer therapies, catering to the significant demand for new therapies in large oncology markets, thereby driving business growth.
- Future Prospects: Despite inherent uncertainties in biotechnology development, Sutro is committed to advancing its product candidates through clinical trials, striving for regulatory approvals and commercialization, which highlights its strategic potential in the cancer treatment landscape.
See More
Sutro Biopharma Regains Nasdaq Compliance with $1 Share Price Post Reverse Split
- Compliance Restoration: Sutro Biopharma confirmed on December 16, 2025, that its common stock has maintained an average closing price of $1, successfully regaining compliance with Nasdaq's continued listing standards, ensuring the company's stability in the capital markets.
- Reverse Split Impact: The company executed a 1:10 reverse stock split on December 3, 2025, which not only elevated the stock price but also ensured that it no longer fell below Nasdaq's minimum bid requirement, thereby boosting investor confidence.
- Market Outlook: Sutro focuses on developing next-generation antibody-drug conjugates (ADCs), with its unique dual-payload platform aimed at overcoming treatment resistance in cancer therapy, indicating significant market demand and strategic growth potential for the company.
- Investor Interest: The company's innovative capabilities in biotechnology and compliance restoration are likely to attract more investor attention, potentially driving further stock price increases and enhancing market confidence in its product pipeline.
See More
