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STRO Should I Buy

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Intellectia

Should You Buy Sutro Biopharma Inc (STRO) Today? Analysis, Price Targets, and 2026 Outlook.

Conclusion
Buy
Latest Price
24.910
1 Day change
3.36%
52 Week Range
26.540
Analysis Updated At
2026/03/27
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Sutro Biopharma Inc (STRO) is a good buy for a beginner investor with a long-term strategy and $50,000-$100,000 available for investment. The stock has strong analyst upgrades, a positive outlook on its STRO-004 pipeline, and a favorable price target increase. Despite short-term financial challenges, its long-term growth potential and innovative drug platform make it a compelling investment opportunity.

Technical Analysis

The technical indicators show mixed signals. The MACD is negative but contracting, suggesting a potential reversal. RSI is neutral at 71.616, and moving averages are bullish (SMA_5 > SMA_20 > SMA_200). The stock is trading near its resistance level of R1: 25.458, indicating potential upward momentum.

Options Data

Bearish
Open Interest Put-Call Ratio
Bearish
Option Volume Put-Call Ratio

Technical Summary

StrongSellSellNeutralBuyStrongBuydotted line Image
Sell
2
Buy
9

Positive Catalysts

  • Multiple analyst upgrades with significant price target increases (e.g., Deutsche Bank to $55, Wells Fargo to $27).

  • Positive sentiment around STRO-004's potential differentiation in efficacy and safety.

  • Revenue growth driven by collaborations with Astellas and Ipsen.

  • Strengthened cash position with $110 million share offering.

Neutral/Negative Catalysts

  • Short-term financial performance challenges with declining revenue, net income, and EPS in Q4

  • No recent significant hedge fund or insider trading activity.

  • Congress trading data unavailable.

Financial Performance

Sutro Biopharma reported a revenue drop of -21.35% YoY to $11.65 million in Q4 2025, with net income down -35.45% YoY to -$46.76 million and EPS declining -39.07% YoY to -$5.35. However, FY25 revenue grew 65.2% to $102.48 million, driven by collaborations, and the company strengthened its cash position with a $110 million share offering.

Growth

Profitability

Efficiency

Analyst Ratings and Price Target Trends

Analysts are highly optimistic about Sutro Biopharma. Deutsche Bank, Wells Fargo, and H.C. Wainwright have all upgraded the stock with significant price target increases. The mean price target is $27.38, reflecting strong confidence in the company's future performance, particularly around its STRO-004 pipeline.

Wall Street analysts forecast STRO stock price to fall
7 Analyst Rating
Wall Street analysts forecast STRO stock price to fall
4 Buy
2 Hold
1 Sell
Moderate Buy
Current: 24.910
sliders
Low
8
Averages
20
High
51
Current: 24.910
sliders
Low
8
Averages
20
High
51
Deutsche Bank
Buy
maintain
$51 -> $55
AI Analysis
2026-03-25
Reason
Deutsche Bank
Price Target
$51 -> $55
AI Analysis
2026-03-25
maintain
Buy
Reason
Deutsche Bank raised the firm's price target on Sutro Biopharma to $55 from $51 and keeps a Buy rating on the shares. The firm says the company's Q4 report highlighted its execution with STRO-004 data in mid-2026.
Wells Fargo
Derek Archila
Equal Weight -> Overweight
upgrade
$8 -> $27
2026-03-24
Reason
Wells Fargo
Derek Archila
Price Target
$8 -> $27
2026-03-24
upgrade
Equal Weight -> Overweight
Reason
Wells Fargo analyst Derek Archila upgraded Sutro Biopharma to Overweight from Equal Weight with a price target of $27, up from $8, post the Q4 report. The update was positive with STRO-004 data on track for mid-2026, the analyst tells investors in a research note. Wells sees share upside on positive data for STRO-004 at current levels. STRO-004's pre-clinical profile demonstrated "early signs of differentiation" on ocular and skin toxicity that could translate to a favorable efficacy and safety profile, the analyst tells investors in a research note.
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