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GTBP Overview

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ET
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Intellectia

Loading chart...

High
0.514
Open
0.480
VWAP
0.49
Vol
1.98M
Mkt Cap
18.54M
Low
0.450
Amount
974.31K
EV/EBITDA(TTM)
--
Total Shares
36.06M
EV
9.61M
EV/OCF(TTM)
--
P/S(TTM)
--
GT Biopharma, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of immuno-oncology therapeutic products based on its proprietary Tri-specific Killer Engager (TriKE) natural killer (NK) cell engager platform. Its TriKE platform is designed to harness and enhance the cancer-killing abilities of a patient’s immune system’s natural killer cells. Its product candidate pipeline includes GTB-3550, GTB-3650, GTB-5550, GTB-7550, GTB-6550, GTB-1050, and other product candidates. GTB-3550 is a TriKE comprised of two single-chain variable fragments (scFv) composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of IL-15. GTB-3650 is a TriKE which targets CD33 on the surface of myeloid leukemias. The Company also has a worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE technology.
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Events Timeline

(ET)
2026-05-14
09:20:00
GT Biopharma Doses First Patient in GTB-5550 Trial
select
2026-04-30 (ET)
2026-04-30
17:00:00
GT Biopharma Files to Sell 9.72M Shares of Common Stock
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2026-03-02 (ET)
2026-03-02
07:10:00
Company Anticipates Cash Balance of Approximately $9 Million by 2026
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2026-02-03 (ET)
2026-02-03
08:40:00
GT Biopharma Receives FDA Clearance for GTB-5550 IND Application
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2026-01-15 (ET)
2026-01-15
08:40:00
GT Biopharma Submits IND Application for GTB-5550
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2025-11-14 (ET)
2025-11-14
09:04:37
GT Biopharma announces Q3 net loss of $3.1M, down from $3.4M the previous year.
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2025-10-23 (ET)
2025-10-23
09:05:35
GT Biopharma announces enrollment progress for GTB-3650 Phase 1 trial
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News

Globenewswire
8.5
06-12Globenewswire
GT Biopharma Advances NK Cell Therapy with TriKE Platform
  • Rise of NK Cell Therapy: GT Biopharma focuses on its TriKE platform to provide scalable, lower-toxicity cancer treatment options, addressing the limitations of T-cell therapies in solid tumors, which is expected to significantly enhance patient treatment experiences.
  • Significant Clinical Progress: By 2026, GT Biopharma has advanced three TriKE candidates into clinical stages, with GTB-5550 receiving FDA approval and initiating Phase 1 trials targeting B7-H3 protein in solid tumors, showcasing its potential in treating refractory cancers.
  • Massive Market Opportunity: GT Biopharma highlights that the global solid tumor market could reach hundreds of billions of dollars, with B7-H3 being an attractive target due to its broad expression across many common and hard-to-treat solid cancers, indicating a strong unmet medical need for its products.
  • Complex Competitive Landscape: GT Biopharma faces fierce competition in NK cell biology from companies like Fate Therapeutics and Nkarta; despite being smaller, its unique TriKE platform and clinical advancements position it well within the rapidly evolving biotech sector.
Newsfilter
8.5
06-12Newsfilter
GT Biopharma Advances NK Cell Therapy with TriKE Platform
  • Rise of NK Cell Therapy: GT Biopharma focuses on its TriKE platform to harness NK cells, aiming to provide scalable cancer treatment solutions that are expected to significantly reduce costs and toxicity, addressing the market's demand for safer therapies.
  • Significant Clinical Progress: As of 2026, GT Biopharma has advanced three TriKE candidates into the clinic, with GTB-5550 receiving FDA clearance and initiating a Phase 1 trial targeting B7-H3 positive tumors, showcasing potential in the solid tumor space.
  • Massive Market Opportunity: The company highlights that the global solid tumor market could reach hundreds of billions of dollars, with B7-H3 being an attractive target due to its broad expression across many difficult-to-treat cancers, presenting substantial commercial value and market appeal.
  • Intense Competitive Landscape: While GT Biopharma is actively pursuing NK cell biology, it faces challenges from larger competitors like Fate Therapeutics, which has stronger capital and technological capabilities in cell therapy, indicating that market competition will continue to intensify.
Globenewswire
8.5
06-08Globenewswire
GT Biopharma Advances Three Drug Candidates into Clinical Trials
  • Clinical Trial Progress: GT Biopharma has advanced three TriKE® candidates into clinical trials, with GTB-5550's first patient dosing on May 14, 2026, marking the company's expansion from blood cancers to the broader solid tumor market, despite its market capitalization remaining below many peers.
  • Drug Development Platform: The TriKE® platform developed by GT Biopharma aims to enhance the immune system's ability to target tumors by linking natural killer cells to specific cancer targets, demonstrating potential across various disease targets, particularly in hematologic malignancies and solid tumors.
  • Clinical Trial Design: The clinical trial for GTB-3650 involves approximately 14 patients and employs a dose-escalation approach, with doses ranging from 1.25 µg/kg/day to 100 µg/kg/day, aimed at evaluating its efficacy in acute myeloid leukemia and high-risk myelodysplastic syndrome.
  • Valuation Gap: Despite significant clinical advancements, GT Biopharma's market valuation remains relatively low, creating a mismatch that attracts speculative interest; if any of its programs succeed, it could lead to substantial stock price appreciation.
Newsfilter
9.0
06-08Newsfilter
GT Biopharma Advances Three Cancer Drug Candidates into Clinical Trials
  • Clinical Trial Progress: GT Biopharma has advanced three TriKE® candidates into clinical stages, with GTB-5550's first patient dosing on May 14, 2026, marking the company's expansion from blood cancers to the broader solid tumor market, indicating its potential in tumor immunotherapy.
  • Drug Development Platform: GT Biopharma's TriKE® platform aims to enhance immune responses by linking natural killer cells to specific cancer targets, with current clinical projects including GTB-3650 for acute myeloid leukemia and GTB-5550 targeting B7-H3-marked solid tumors, showcasing a diversified treatment strategy.
  • Valuation Gap: Despite advancing three candidates into clinical trials, GT Biopharma's market valuation remains below many peers, reflecting a tension between funding and clinical progress that attracts speculative interest; if any program succeeds, it could significantly enhance the company's value.
  • Trial Design: The GTB-5550 trial employs a basket trial design, allowing patients with multiple tumor types to enroll under one protocol, which is an efficient approach for the company to quickly gather early signals and assess responses across different cancers while managing limited resources.
Newsfilter
9.0
06-02Newsfilter
GT Biopharma Enters Clinical Trials with Three Drugs
  • Clinical Trial Progress: On May 14, 2026, GT Biopharma announced the first patient dosing of its third drug, GTB-5550, in a clinical trial, marking a significant advancement for the company, particularly in expanding into the solid tumor market.
  • Dual Clinical Trials: GT Biopharma is conducting clinical trials for both GTB-5550 and GTB-3650 simultaneously, the latter targeting patients with relapsed blood cancers, demonstrating the company's ability to advance multiple projects effectively despite limited resources, thereby enhancing its market competitiveness.
  • Innovative Drug Platform: GTB-5550 is the first dual-nanobody construct from the company's TriKE platform, designed for more patient-friendly subcutaneous dosing, which is expected to provide a better treatment experience and further solidify the company's position in the cancer immunotherapy field.
  • Financing Challenges: Despite clinical progress, the company's cash reserves of approximately $9 million are only sufficient to fund operations into the fourth quarter of 2026, presenting financing pressures and potential dilution risks, necessitating cautious evaluation from investors regarding its future development.
PRnewswire
8.5
05-29PRnewswire
GT Biopharma: Three Drugs Enter Human Trials
  • Market Valuation Struggles: As of mid-May 2026, GT Biopharma's market cap stood at approximately $13 million, indicating a significant undervaluation of this clinical-stage immuno-oncology company, prompting investors to consider potential value recovery.
  • Significant Clinical Progress: GT Biopharma has advanced three TriKE candidates into clinical trials, with GTB-3650 targeting treatment-resistant blood cancers, and a critical data update expected in the second half of 2026, which could influence the company's future trajectory.
  • Innovative Therapeutic Platform: The company holds exclusive rights to the TriKE platform designed to activate natural killer cells to directly attack tumors, leveraging technology from the University of Minnesota, showcasing immense potential in the tumor immunotherapy space that could transform existing treatment paradigms.
  • Enormous Market Opportunity: The global oncology market is projected to grow from $139 billion in 2025 to $268 billion by 2034, and if GT Biopharma's product line succeeds, it could secure a significant position in this vast market, leading to substantial commercial returns.
Wall Street analysts forecast GTBP stock price to rise
1 Analyst Rating
Wall Street analysts forecast GTBP stock price to rise
1 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Current: 0.000
sliders
Low
8.00
Averages
8.00
High
8.00
Roth Capital
Jonathan Aschoff
Buy
downgrade
$8 -> $3
AI Analysis
2026-03-03
Reason
Roth Capital
Jonathan Aschoff
Price Target
$8 -> $3
AI Analysis
2026-03-03
downgrade
Buy
Reason
Roth Capital analyst Jonathan Aschoff lowered the firm's price target on GT Biopharma to $3 from $8 and keeps a Buy rating on the shares. The firm is citing the company evaluating second-generation TriKE GTB-3650 in a Phase 1 trial in rel/ref CD33 expressing hematologic malignancies, predominantly AML and high-risk MDS, with initial data expected in 3Q26 following completion of cohort 5, the analyst tells investors in a research note.
Roth Capital
Buy
downgrade
$8 -> $3
2026-03-02
Reason
Roth Capital
Price Target
$8 -> $3
2026-03-02
downgrade
Buy
Reason
Roth Capital lowered the firm's price target on GT Biopharma to $3 from $8 and keeps a Buy rating on the shares. As of January, GT Biopharma held pro forma cash of $9M, sufficient to fund operations through 2026, the analyst tells investors in a research note. The company is advancing its pipeline with a Phase 1 trial of second-generation TriKE GTB-3650 in relapsed/refractory CD33-positive hematologic malignancies, with initial data expected in 3Q26, and plans to start a Phase 1 basket trial of GTB-5550 in mid-2026 for B7-H3-expressing solid tumors, while financial models have been adjusted for increased dilution, the firm says.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for GTBP
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Valuation Metrics

The current forward P/E ratio for GT Biopharma Inc (GTBP.O) is 17.33, compared to its 5-year average forward P/E of -0.80. For a more detailed relative valuation and DCF analysis to assess GT Biopharma Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-0.80
Current PE
17.33
Overvalued PE
5.80
Undervalued PE
-7.40

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
0.00
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.00
Undervalued EV/EBITDA
0.00

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
0.00
Current PS
0.00
Overvalued PS
0.00
Undervalued PS
0.00

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Frequently Asked Questions

What is GT Biopharma Inc (GTBP) stock price today?

The current price of GTBP is 0.514 USD — it has increased 11.98

What is GT Biopharma Inc (GTBP)'s business?

GT Biopharma, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of immuno-oncology therapeutic products based on its proprietary Tri-specific Killer Engager (TriKE) natural killer (NK) cell engager platform. Its TriKE platform is designed to harness and enhance the cancer-killing abilities of a patient’s immune system’s natural killer cells. Its product candidate pipeline includes GTB-3550, GTB-3650, GTB-5550, GTB-7550, GTB-6550, GTB-1050, and other product candidates. GTB-3550 is a TriKE comprised of two single-chain variable fragments (scFv) composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of IL-15. GTB-3650 is a TriKE which targets CD33 on the surface of myeloid leukemias. The Company also has a worldwide license agreement with the University of Minnesota to further develop and commercialize therapies using TriKE technology.

What is the price predicton of GTBP Stock?

Wall Street analysts forecast GTBP stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for GTBP is8.00 USD with a low forecast of 8.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is GT Biopharma Inc (GTBP)'s revenue for the last quarter?

GT Biopharma Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is GT Biopharma Inc (GTBP)'s earnings per share (EPS) for the last quarter?

GT Biopharma Inc. EPS for the last quarter amounts to -0.11 USD, decreased -66.67

How many employees does GT Biopharma Inc (GTBP). have?

GT Biopharma Inc (GTBP) has 1 emplpoyees as of June 21 2026.

What is GT Biopharma Inc (GTBP) market cap?

Today GTBP has the market capitalization of 18.54M USD.