Ascentage Pharma Reports Significant Revenue Growth in 2025 Financial Results
Written by Emily J. Thompson, Senior Investment Analyst
Updated: 5 days ago
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Should l Buy AAPG?
Source: Newsfilter
- Revenue Growth: In 2025, Ascentage Pharma's product sales and commercial rights revenues surged by 90% year-over-year to $82.1 million (RMB 574.1 million), indicating strong market performance and growth potential for the company.
- Strong Sales of Olverembatinib: Sales of Olverembatinib increased by 81% year-over-year to $62.2 million (RMB 435.3 million), reflecting the drug's growing acceptance and demand in the Chinese market, thereby enhancing the company's market position.
- Lisaftoclax Market Performance: Since its launch in July 2025, Lisaftoclax generated $10.1 million (RMB 70.6 million) in sales over five months, demonstrating strong market acceptance and potential growth opportunities for the new product.
- Clinical Trial Progress: The company is currently conducting nine registrational Phase III clinical trials globally, with four cleared by the FDA and EMA, showcasing Ascentage Pharma's ongoing commitment to innovative drug development and strategic positioning.
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Analyst Views on AAPG
Wall Street analysts forecast AAPG stock price to rise
6 Analyst Rating
6 Buy
0 Hold
0 Sell
Strong Buy
Current: 23.150
Low
45.00
Averages
48.67
High
51.00
Current: 23.150
Low
45.00
Averages
48.67
High
51.00
About AAPG
Ascentage Pharma Group International is an investment holding company primarily engaged in the discovery, development, and commercialization of therapies for hematologic malignancies. The Company's main products include Olverembatinib (HQP1351), Lisaftoclax (APG-2575), Alrizomadlin (APG-115), Pelcitoclax (APG-1252), APG-5918, and APG-2449. The Company's products are primarily used to treat chronic myeloid leukemia (CML), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia (ALL), myelodysplastic syndrome (MDS) and multiple myeloma (MM). The Company primarily conducts its businesses in domestic market.
About the author

Emily J. Thompson
Emily J. Thompson, a Chartered Financial Analyst (CFA) with 12 years in investment research, graduated with honors from the Wharton School. Specializing in industrial and technology stocks, she provides in-depth analysis for Intellectia’s earnings and market brief reports.
- Revenue Growth: In 2025, Ascentage Pharma's product sales and commercial rights revenues surged by 90% year-over-year to $82.1 million (RMB 574.1 million), indicating strong market performance and growth potential for the company.
- Strong Sales of Olverembatinib: Sales of Olverembatinib increased by 81% year-over-year to $62.2 million (RMB 435.3 million), reflecting the drug's growing acceptance and demand in the Chinese market, thereby enhancing the company's market position.
- Lisaftoclax Market Performance: Since its launch in July 2025, Lisaftoclax generated $10.1 million (RMB 70.6 million) in sales over five months, demonstrating strong market acceptance and potential growth opportunities for the new product.
- Clinical Trial Progress: The company is currently conducting nine registrational Phase III clinical trials globally, with four cleared by the FDA and EMA, showcasing Ascentage Pharma's ongoing commitment to innovative drug development and strategic positioning.
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- Efficacy Data Update: Olverembatinib achieved a complete cytogenetic response rate of 76.7% in chronic-phase CML patients, demonstrating its strong potential as a second-line treatment, which may facilitate its advancement to earlier treatment lines.
- Deepening Molecular Responses: With extended treatment duration, the major molecular response rate reached 60% at 21 cycles, indicating that patient responses deepen over time, enhancing its clinical application prospects.
- Consistent Safety Profile: The safety data for Olverembatinib remained consistent with previously reported results, with no new safety signals, ensuring its acceptability and safety for patient use.
- Ongoing Global Registrational Studies: Ascentage Pharma is conducting three global registrational Phase III studies to evaluate Olverembatinib across multiple indications, showcasing the company's commitment to addressing unmet medical needs worldwide.
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- Clinical Trial Results: At the ASH Annual Meeting, Ascentage Pharma showcased data from its new drug Olverembatinib combined with low-intensity chemotherapy, revealing a best minimal residual disease (MRD) negativity rate of 66.0% in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia patients, indicating the drug's potential in treatment.
- Safety Analysis: The combination of Olverembatinib and low-intensity chemotherapy demonstrated a favorable safety profile, with common grade 3 or higher adverse events including neutropenia (63.6%) and thrombocytopenia (56.4%), suggesting its acceptability in clinical applications.
- Global Registration Progress: The POLARIS-1 study of Olverembatinib has received clearance from the FDA and EMA, marking a significant milestone in the global development of the drug and potentially offering new treatment options for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
- Market Potential: Ascentage Pharma has signed an exclusive option agreement with Takeda, which, if exercised, would grant Takeda global rights to develop and commercialize Olverembatinib outside of mainland China, Hong Kong, Macau, and Taiwan, thereby expanding its market influence.
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