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SPRO Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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0.000
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
2.880
Open
2.840
VWAP
2.81
Vol
603.73K
Mkt Cap
160.94M
Low
2.760
Amount
1.69M
EV/EBITDA(TTM)
16.86
Total Shares
57.89M
EV
120.67M
EV/OCF(TTM)
--
P/S(TTM)
2.46
Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.
Show More

Events Timeline

(ET)
2025-12-19
08:20:00
Spero Therapeutics Receives $25 Million Milestone Payment Triggered by GSK's NDA Submission
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2025-11-28 (ET)
2025-11-28
08:08:43
Spero Therapeutics Reveals Inducement Grant in Accordance with Nasdaq Listing Regulations
select
2025-10-21 (ET)
2025-10-21
05:46:08
Spero Therapeutics and GSK Reveal Efficacy and Safety Outcomes of PIVOT-PO Trial
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2025-05-28 (ET)
2025-05-28
07:17:32
GSK reports PIVOT-PO study for tebipenem HBr stopped early for efficacy
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2025-05-28
07:05:59
Spero Therapeutics, GSK announce Phase 3 PIVOT-PO trial met primary endpoint
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2025-04-28 (ET)
2025-04-28
16:08:20
Spero Therapeutics appoints Esther Rajavelu will serve as CEO
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2025-03-27 (ET)
2025-03-27
16:15:34
Spero Therapeutics reports Q4 EPS (38c), consensus (31c)
select

News

moomoo
9.5
03-26moomoo
Spero Therapeutics Reports Fourth Quarter Revenue of $41.3 Million
  • Company Overview: Super Therapeutics reported a revenue of USD 41.3 million for the fourth quarter.
  • Financial Performance: The revenue figure indicates a significant financial performance for the company during this period.
seekingalpha
9.5
03-26seekingalpha
Spero Therapeutics Reports Strong Q4 Earnings
  • Earnings Highlights: Spero Therapeutics reported a Q4 non-GAAP EPS of $0.53, indicating a significant improvement in profitability, which enhances the company's competitive position in the market.
  • Revenue Surge: The company achieved Q4 revenue of $41.3 million, a remarkable 174.6% year-over-year increase, primarily driven by successful product launches and rising market demand, suggesting strong growth potential ahead.
  • Cash Position: As of December 31, 2025, Spero had cash and cash equivalents of $40.3 million, which is projected to be sufficient to fund operations into 2028, ensuring financial stability and ongoing operational capacity.
  • Market Outlook: Spero Therapeutics' Tebipenem is receiving support on its FDA pathway, with market analysts expressing optimism about its future performance, which is expected to create additional investment opportunities and market recognition for the company.
moomoo
9.5
03-26moomoo
SPERO THERAPEUTICS REPORTS Q4 NET INCOME OF $31.52 MILLION
  • Company Overview: The article discusses the financial performance of a company named Spero Therapeutics, focusing on its net income for the fourth quarter.

  • Financial Highlights: Spero Therapeutics reported a net income of USD 31.52 million for Q4, indicating a significant financial achievement for the company.

moomoo
9.5
03-26moomoo
Spero Therapeutics Reports Q4 Operating Income of $31.405 Million
  • Company Overview: Super Therapeutics reported a Q4 income of $31.405 million from operations.
  • Financial Performance: The reported income reflects the company's operational success during the fourth quarter.
moomoo
9.5
03-26moomoo
Spero Therapeutics Reports Q4 Operating Expenses of $9.892 Million
  • Financial Overview: Super Therapeutics reported operating expenses of USD 9.892 million for the fourth quarter.
  • Performance Insight: The financial results indicate the company's spending patterns and operational costs during the specified period.
Globenewswire
9.0
2025-12-19Globenewswire
Spero Therapeutics and GSK Submit NDA for Tebipenem HBr, Triggering $25 Million Milestone Payment
  • NDA Submission: Spero Therapeutics and GSK have submitted a New Drug Application (NDA) for tebipenem HBr, an antibiotic for complicated urinary tract infections, triggering a $25 million milestone payment expected in Q1 2026, significantly enhancing the company's liquidity.
  • Clinical Trial Success: The NDA is supported by positive results from the Phase 3 PIVOT-PO trial, which was stopped early for efficacy in May 2025, indicating the drug's potential in the treatment landscape and likely boosting market acceptance.
  • Exclusive Licensing Agreement: Spero granted GSK exclusive commercialization rights for tebipenem HBr, except in certain Asian territories where Meiji retains rights, a strategy that aims to maximize revenue potential across global markets.
  • Government Funding Support: Select studies for tebipenem HBr have been partially funded by federal funds from the Department of Health and Human Services, which not only reduces R&D costs but also enhances the company's influence in public health initiatives.
Wall Street analysts forecast SPRO stock price to rise
2 Analyst Rating
Wall Street analysts forecast SPRO stock price to rise
0 Buy
2 Hold
0 Sell
Hold
Current: 0.000
sliders
Low
4.00
Averages
4.00
High
4.00
Current: 0.000
sliders
Low
4.00
Averages
4.00
High
4.00
No data

No data

Valuation Metrics

The current forward P/E ratio for Spero Therapeutics Inc (SPRO.O) is 0.00, compared to its 5-year average forward P/E of -2.04. For a more detailed relative valuation and DCF analysis to assess Spero Therapeutics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-2.04
Current PE
0.00
Overvalued PE
0.08
Undervalued PE
-4.17

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-0.96
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.88
Undervalued EV/EBITDA
-2.80

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
11.29
Current PS
0.00
Overvalued PS
26.15
Undervalued PS
-3.57

Financials

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Frequently Asked Questions

What is Spero Therapeutics Inc (SPRO) stock price today?

The current price of SPRO is 2.78 USD — it has increased 0

What is Spero Therapeutics Inc (SPRO)'s business?

Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.

What is the price predicton of SPRO Stock?

Wall Street analysts forecast SPRO stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SPRO is4.00 USD with a low forecast of 4.00 USD and a high forecast of 4.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Spero Therapeutics Inc (SPRO)'s revenue for the last quarter?

Spero Therapeutics Inc revenue for the last quarter amounts to 41.30M USD, increased 174.51

What is Spero Therapeutics Inc (SPRO)'s earnings per share (EPS) for the last quarter?

Spero Therapeutics Inc. EPS for the last quarter amounts to 0.46 USD, decreased -221.05

How many employees does Spero Therapeutics Inc (SPRO). have?

Spero Therapeutics Inc (SPRO) has 25 emplpoyees as of April 15 2026.

What is Spero Therapeutics Inc (SPRO) market cap?

Today SPRO has the market capitalization of 160.94M USD.