SPRO Technical

Technical Sentiment Analysis for Spero Therapeutics Inc (SPRO) As of 2026-05-22, Spero Therapeutics Inc (SPRO) is exhibiting a Strong Buy technical sentiment. Our proprietary analysis, which aggregates 10 technical signals, shows that 8 indicators are flashing buy, while 2 are indicating sell.

Momentum Indicators: RSI, MACD & Overbought/Oversold Status Currently, the Relative Strength Index (RSI) for SPRO stands at 57.787, which suggests a Neutral condition. Meanwhile, the MACD (12, 26) indicator is at 0.0253, providing a Buy signal for short-term momentum. Other oscillators like the Stochastic Oscillator at 62.783 and the Commodity Channel Index (CCI) at 155.936 further confirm a 0.2 outlook for the stock.

Support, Resistance & Moving Averages From a structural perspective, SPRO is trading above its 60-day moving average of $2.542 and above its 200-day long-term moving average of $2.332. Key price levels to watch include the immediate resistance at $2.889 and strong support at $2.374. A break above $2.889 could signal a bull continuation, while falling below $2.374 may test the next Fibonacci floor at $2.114.