Loading...

Intellectia LogoIntellectia
AI Trading Bot
Features
Markets
News
Resources
Pricing
Get Started
  1. Home
  2. Stock
  3. SEPN
SEPN logo

SEPN Overview

-
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
OverviewStock Price PredictionTechnicalValuationFinancialsEarningsShould I BuyNews & Events
an image of Intellectia Logoan image of Intellectia

Most Trusted AI Platform for Winning Trades

TwitterYoutubeQuoraDiscordLinkedinTelegram

Copyright © 2026 Intellectia.AI. All Rights Reserved.

Company

  • Home
  • Contact
  • About Us
  • Press
  • Privacy
  • Terms of Service
  • Service Terms of Use

Resources

  • Blog
  • Tutorial
  • Help Center
  • Affiliate Program

Markets

  • Market Analysis
  • Crypto
  • Featured Screeners
  • AI Earnings Calendar
  • Market Movers
  • Stock Monitor
  • Economic Calendar
  • All US Stocks
  • All Cryptos

Tools

  • Dividend Calculator
  • Dividend Yield Calculator
  • Options Profit Calculator

Features

  • QuantAI Alpha Pick
  • SwingMax Portfolio
  • Swing Trading
  • AI Stock Picker
  • Whales Auto Tracker
  • Daytrading Center
  • Patterns Detection
  • AI Screener
  • Financial AI Agent
  • Backtesting Playground
  • AI Earnings Prediction
  • Stock Monitor
  • Technical Analysis

News

  • Overview
  • Top News
  • Daily Market Brief
  • Earnings Analysis
  • Newswire
  • Stock News
  • Crypto News
  • Institution News
  • Congress News
  • Monitor News

Compare

  • TradingView
  • SeekingAlpha
Intellectia

Loading chart...

High
25.400
Open
24.860
VWAP
24.85
Vol
595.43K
Mkt Cap
1.11B
Low
24.490
Amount
14.80M
EV/EBITDA(TTM)
--
Total Shares
44.91M
EV
716.75M
EV/OCF(TTM)
6.50
P/S(TTM)
23.93
Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.
Show More

Events Timeline

(ET)
2026-04-13
08:10:00
Septerna Doses First Participants in SEP-479 Clinical Trial
select
2026-03-10 (ET)
2026-03-10
16:40:00
Septerna Files Automatic Mixed Securities Shelf
select
2026-03-09 (ET)
2026-03-09
16:40:00
Septerna Reports Q4 Revenue of $24.12M
select
2026-03-01 (ET)
2026-03-01
11:30:00
Septerna Announces Positive Results for SEP-631 Clinical Trial
select
2026-01-08 (ET)
2026-01-08
16:20:00
Septerna Appoints Mark Wilson as Chief Legal Officer
select

News

CNBC
5.0
04-22CNBC
Trump Extends Ceasefire with Iran Amid Market Volatility
  • Ceasefire Extension: President Trump announced the extension of the ceasefire with Iran, originally set to expire today, until Tehran presents a 'unified proposal,' aiming to ease tensions in the Middle East, which could impact global oil prices.
  • Boeing Earnings Beat: Boeing reported a smaller-than-expected loss per share in Q1 and exceeded revenue expectations, leading to a more than 3% rise in its stock price, indicating a gradual recovery in a challenging aviation market that may boost investor confidence.
  • Fed Nominee Scrutiny: Kevin Warsh, Trump's nominee for Federal Reserve Chair, faced tough questions during his confirmation hearing regarding his independence and financial background, despite asserting he wouldn't lower interest rates solely at Trump's request, potentially affecting market expectations for Fed policy.
  • Best Buy's New CEO: Best Buy announced that insider Jason Bonfig will succeed CEO Corie Barry on October 31, tasked with driving sales amid a lukewarm market while the company seeks to enhance its presence in the artificial intelligence product sector.
Newsfilter
8.5
04-22Newsfilter
Trump Extends Ceasefire with Iran Amid Market Volatility
  • Ceasefire Extension: Trump announced the extension of the ceasefire with Iran, originally set to expire today, now lasting until Tehran provides a 'unified proposal', aiming to alleviate market concerns over geopolitical risks, which could positively impact oil prices and stock markets.
  • Boeing Stock Surge: Boeing shares rose over 3% this morning after the company reported a smaller-than-expected loss per share and exceeded revenue expectations in Q1, demonstrating resilience during tough times, with the CEO set to discuss results on CNBC today, further boosting market confidence.
  • Fed Nominee Scrutiny: Kevin Warsh, Trump's nominee for the Federal Reserve chair, faced tough questions during his confirmation hearing, asserting he wouldn't lower interest rates at Trump's request, raising concerns about his independence and financial background, which may influence market expectations for future monetary policy.
  • Amazon Enters GLP-1 Market: Amazon's primary care arm launched a new program to ease access to weight-loss drugs, enhancing its competitiveness in the healthcare sector while potentially boosting the market performance of related stocks, reflecting the company's strategic expansion into pharmaceuticals.
CNBC
7.5
04-21CNBC
Amazon Launches GLP-1 Management Program to Transform Weight Loss Treatment
  • Market Expansion: Amazon is launching a new GLP-1 management program through its primary care arm, Amazon One Medical, aiming to integrate obesity treatment into routine care, which is expected to significantly enhance patient adherence to long-term weight management.
  • Transparent Pricing: The program offers insured pricing starting as low as $25 per month, while cash-paying patients will find oral medications starting at $149 per month and injectable treatments like Wegovy at $299, positioning Amazon competitively in the market despite similar pricing.
  • Convenient Services: Amazon Pharmacy will provide on-demand prescription renewals, starting at $29 for message consultations and $49 for video care, which is likely to attract more customers and enhance loyalty and market share.
  • Logistical Advantage: Amazon plans to expand its same-day drug delivery service to 4,500 cities by the end of 2026, leveraging its robust logistics network and consumer reach to solidify its position within the healthcare system.
Newsfilter
8.5
04-21Newsfilter
Amazon Launches GLP-1 Weight Loss Program
  • Increased Market Competition: Amazon's launch of the GLP-1 management program through One Medical integrates obesity treatment with routine care, likely pressuring shares of companies like Hims & Hers Health and Viking Therapeutics, which fell following the announcement.
  • Transparent Pricing: The pricing for GLP-1 medications will start as low as $25 per month for insured patients, aiming to attract more customers by simplifying access to medications and enhancing market share.
  • Convenient Drug Delivery: Amazon plans to expand same-day drug delivery to 4,500 cities by the end of 2026, leveraging its robust logistics network to improve customer experience and gain an edge in the competitive weight loss drug market.
  • Diverse Treatment Options: Through Amazon Pharmacy, patients can access various GLP-1 medications, including Novo Nordisk's Wegovy and Eli Lilly's Zepbound, further driving the company's expansion into the healthcare sector.
seekingalpha
9.5
03-09seekingalpha
Septerna, Inc. Q4 Earnings Exceed Expectations
  • Strong Earnings Report: Septerna, Inc. reported a Q4 GAAP EPS of -$0.24, beating expectations by $0.02, indicating an improvement in financial performance despite still being in a loss position.
  • Significant Revenue Growth: The company achieved Q4 revenue of $24.1 million, soaring 11950% year-over-year and exceeding market expectations by $8.54 million, demonstrating robust demand and rapid growth potential for its products or services.
  • Positive Future Outlook: With the Phase 1 readout of SEP-631 approaching, Septerna anticipates a key market driver in 2026, which could further boost the company's stock price and market recognition.
  • Quant Rating Improvement: Seeking Alpha's quant rating on Septerna, Inc. reflects growing market confidence in its future performance, indicating investor recognition of the company's strategic direction and growth potential.
NASDAQ.COM
9.0
03-02NASDAQ.COM
Septerna Reports Positive Phase 1 Results for SEP-631 in Mast Cell-Driven Diseases
  • Clinical Trial Success: Septerna's SEP-631 demonstrated good tolerability and pharmacokinetic characteristics in its Phase 1 clinical trial for mast cell-driven diseases, supporting once-daily oral dosing with a half-life of 24 hours, indicating its potential for treating chronic spontaneous urticaria and other conditions.
  • Efficacy Validation: At a dose of 10 mg, SEP-631 showed significant suppression of skin wheal formation, with nearly complete inhibition observed at 90 mg and 200 mg doses, demonstrating a dose-dependent response that further validates its application in mast cell-driven diseases.
  • Follow-Up Research Plans: Based on the positive Phase 1 results, Septerna plans to initiate a Phase 2b clinical trial for chronic spontaneous urticaria in the second half of 2023, aiming to evaluate the efficacy of SEP-631 in adult patients who remain symptomatic despite treatment with second-generation antihistamines.
  • Multiple Indication Exploration: In addition to chronic spontaneous urticaria, Septerna is also exploring the efficacy of SEP-631 in other mast cell-driven diseases, including atopic dermatitis, interstitial cystitis, migraine, and asthma, showcasing its broad market potential.
Wall Street analysts forecast SEPN stock price to rise
8 Analyst Rating
Wall Street analysts forecast SEPN stock price to rise
8 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
25.00
Averages
33.14
High
43.00
Current: 0.000
sliders
Low
25.00
Averages
33.14
High
43.00
JPMorgan
NULL -> Overweight
upgrade
$34 -> $38
AI Analysis
2026-03-24
Reason
JPMorgan
Price Target
$34 -> $38
AI Analysis
2026-03-24
upgrade
NULL -> Overweight
Reason
JPMorgan raised the firm's price target on Septerna to $38 from $34 and keeps an Overweight rating on the shares. The firm updated the company's model post the Q4 report.
Truist
Srikripa Devarakonda
Buy
maintain
$34 -> $35
2026-03-11
Reason
Truist
Srikripa Devarakonda
Price Target
$34 -> $35
2026-03-11
maintain
Buy
Reason
Truist analyst Srikripa Devarakonda raised the firm's price target on Septerna to $35 from $34 and keeps a Buy rating on the shares. The firm is incrementally positive on the company after its Q4 update, where clinical trial timelines remain on track, the analyst tells investors in a research note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for SEPN
Unlock Now

Valuation Metrics

The current forward P/E ratio for Septerna Inc (SEPN.O) is 107.53, compared to its 5-year average forward P/E of 6.87. For a more detailed relative valuation and DCF analysis to assess Septerna Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
6.87
Current PE
107.53
Overvalued PE
70.29
Undervalued PE
-56.56

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-3.65
Current EV/EBITDA
-23.78
Overvalued EV/EBITDA
2.52
Undervalued EV/EBITDA
-9.81

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
111.91
Current PS
16.68
Overvalued PS
382.96
Undervalued PS
-159.15

Financials

AI Analysis
Annual
Quarterly

Related Community Screener

which bio stocks is declining
Intellectia · 12 candidates
Market Cap: >= 1000.00MSector: Healthcare, Healthcare Services & EquipmentIndustry: Biotechnology & Medical ResearchVolume: >= 500,000Price Change Pct: <= $-2.00Moving Average Relationship: PriceBelowMA20
Ticker
Name
Market Cap$
top bottom
TEM logo
TEM
Tempus AI Inc
7.70B
IBRX logo
IBRX
Immunitybio Inc
7.52B
PTGX logo
PTGX
Protagonist Therapeutics Inc
6.31B
ADPT logo
ADPT
Adaptive Biotechnologies Corp
1.97B
TYRA logo
TYRA
Tyra Biosciences Inc
1.90B
GRAL logo
GRAL
Grail Inc
1.87B
best short term day trading stock
Intellectia · 3787 candidates
Price: $1.00 - $200.00List Exchange: XNYS, XNAS, XASEMonthly Average Dollar Volume: >= 100,000
Ticker
Name
Market Cap$
top bottom
ZNTL logo
ZNTL
Zentalis Pharmaceuticals Inc
210.44M
LAMR logo
LAMR
Lamar Advertising Co
13.37B
REI logo
REI
Ring Energy Inc
203.08M
SSTK logo
SSTK
Shutterstock Inc
674.53M
AHCO logo
AHCO
Adapthealth Corp
1.42B
CRH logo
CRH
CRH PLC
80.90B

Whales Holding SEPN

V
VR Management, LLC
Holding
SEPN
+19.98%
3M Return
A
Artal Group S.A.
Holding
SEPN
+14.84%
3M Return
D
Driehaus Capital Management LLC
Holding
SEPN
+13.41%
3M Return
A
Avoro Capital Advisors LLC
Holding
SEPN
+9.85%
3M Return
B
BVF Partners L.P.
Holding
SEPN
+5.92%
3M Return
S
Soleus Capital Management, L.P.
Holding
SEPN
+3.38%
3M Return

Trading Trends

    Insider
    Hedge Fund
    Congress Trading

People Also Watch

Frequently Asked Questions

What is Septerna Inc (SEPN) stock price today?

The current price of SEPN is 24.67 USD — it has decreased -1.2

What is Septerna Inc (SEPN)'s business?

Septerna, Inc. is a clinical-stage biotechnology company. The Company is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. It is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. It is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.

What is the price predicton of SEPN Stock?

Wall Street analysts forecast SEPN stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for SEPN is33.14 USD with a low forecast of 25.00 USD and a high forecast of 43.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Septerna Inc (SEPN)'s revenue for the last quarter?

Septerna Inc revenue for the last quarter amounts to 24.12M USD, increased 11276.42

What is Septerna Inc (SEPN)'s earnings per share (EPS) for the last quarter?

Septerna Inc. EPS for the last quarter amounts to -0.24 USD, decreased -61.90

How many employees does Septerna Inc (SEPN). have?

Septerna Inc (SEPN) has 130 emplpoyees as of April 28 2026.

What is Septerna Inc (SEPN) market cap?

Today SEPN has the market capitalization of 1.11B USD.