
SEPN Valuation
Septerna Inc
- Overview
- Forecast
- Valuation
- Earnings
SEPN Relative Valuation
SEPN's fair value is calculated using relative valuation, based on historical P/E and P/S ranges and their premiums/discounts relative to a competitor average, adjusted by weights. If the market price exceeds this fair value range, SEPN is overvalued; if below, it's undervalued.
Historical Valuation
Septerna Inc (SEPN) is now in the Fair zone, suggesting that its current forward PS ratio of 4.93 is considered Fairly compared with the five-year average of 0.94. The fair price of Septerna Inc (SEPN) is between to according to relative valuation methord.
Relative Value
Fair Zone
-
Current Price:11.68
Fair
-16.10
PE
1Y
3Y
5Y
Trailing
Forward
0.00
EV/EBITDA
Septerna Inc. (SEPN) has a current EV/EBITDA of 0.00. The 5-year average EV/EBITDA is -1.73. The thresholds are as follows: Strongly Undervalued below -10.14, Undervalued between -10.14 and -5.94, Fairly Valued between 2.47 and -5.94, Overvalued between 2.47 and 6.68, and Strongly Overvalued above 6.68. The current Forward EV/EBITDA of 0.00 falls within the Historic Trend Line -Fairly Valued range.
-7.35
EV/EBIT
Septerna Inc. (SEPN) has a current EV/EBIT of -7.35. The 5-year average EV/EBIT is -1.14. The thresholds are as follows: Strongly Undervalued below -15.42, Undervalued between -15.42 and -8.28, Fairly Valued between 6.00 and -8.28, Overvalued between 6.00 and 13.14, and Strongly Overvalued above 13.14. The current Forward EV/EBIT of -7.35 falls within the Historic Trend Line -Fairly Valued range.
4.93
PS
Septerna Inc. (SEPN) has a current PS of 4.93. The 5-year average PS is 201.59. The thresholds are as follows: Strongly Undervalued below -501.39, Undervalued between -501.39 and -149.90, Fairly Valued between 553.09 and -149.90, Overvalued between 553.09 and 904.58, and Strongly Overvalued above 904.58. The current Forward PS of 4.93 falls within the Historic Trend Line -Fairly Valued range.
4.58
P/OCF
Septerna Inc. (SEPN) has a current P/OCF of 4.58. The 5-year average P/OCF is -1.09. The thresholds are as follows: Strongly Undervalued below -15.15, Undervalued between -15.15 and -8.12, Fairly Valued between 5.94 and -8.12, Overvalued between 5.94 and 12.97, and Strongly Overvalued above 12.97. The current Forward P/OCF of 4.58 falls within the Historic Trend Line -Fairly Valued range.
-89.35
P/FCF
Septerna Inc. (SEPN) has a current P/FCF of -89.35. The 5-year average P/FCF is 0.94. The thresholds are as follows: Strongly Undervalued below -55.59, Undervalued between -55.59 and -27.32, Fairly Valued between 29.20 and -27.32, Overvalued between 29.20 and 57.46, and Strongly Overvalued above 57.46. The current Forward P/FCF of -89.35 falls within the Strongly Undervalued range.
Septerna Inc (SEPN) has a current Price-to-Book (P/B) ratio of 1.38. Compared to its 3-year average P/B ratio of 0.16 , the current P/B ratio is approximately 766.72% higher. Relative to its 5-year average P/B ratio of 0.16, the current P/B ratio is about 766.72% higher. Septerna Inc (SEPN) has a Forward Free Cash Flow (FCF) yield of approximately -15.93%. Compared to its 3-year average FCF yield of -14.77%, the current FCF yield is approximately 7.83% lower. Relative to its 5-year average FCF yield of -14.77% , the current FCF yield is about 7.83% lower.
1.38
P/B
Median3y
0.16
Median5y
0.16
-15.93
FCF Yield
Median3y
-14.77
Median5y
-14.77
Competitors Valuation Multiple
The average P/S ratio for SEPN's competitors is 16.40, providing a benchmark for relative valuation. Septerna Inc Corp (SEPN) exhibits a P/S ratio of 4.93, which is -69.96% above the industry average. Given its robust revenue growth of %, this premium appears unsustainable.
Performance Decomposition
1Y
3Y
5Y
Market capitalization of SEPN increased by 0.00% over the past 1 year. The primary factor behind the change was an decrease in Unknown from 0.00 to 0.00.
The secondary factor is the Unknown, contributed 0.00%to the performance.
Overall, the performance of SEPN in the past 1 year is driven by Unknown.
People Also Watch

VLRS
Controladora Vuela Compania de Aviacion SAB de CV
5.840
USD
-1.18%

IRMD
IRadimed Corp
70.150
USD
-1.20%

AVDL
Avadel Pharmaceuticals PLC
13.500
USD
-1.96%

QURE
Uniqure NV
15.780
USD
+8.08%

EGBN
Eagle Bancorp Inc
18.420
USD
+1.66%

WRLD
World Acceptance Corp
170.650
USD
-0.95%

ODP
ODP Corp
20.780
USD
+2.31%

TIPT
Tiptree Inc
22.370
USD
-2.57%

HUYA
HUYA Inc
3.300
USD
-4.62%

RLAY
Relay Therapeutics Inc
3.390
USD
-0.88%
FAQ

Is Septerna Inc (SEPN) currently overvalued or undervalued?
Septerna Inc (SEPN) is now in the Fair zone, suggesting that its current forward PS ratio of 4.93 is considered Fairly compared with the five-year average of 0.94. The fair price of Septerna Inc (SEPN) is between to according to relative valuation methord.

What is Septerna Inc (SEPN) fair value?

How does SEPN's valuation metrics compare to the industry average?

What is the current P/B ratio for Septerna Inc (SEPN) as of Aug 15 2025?

What is the current FCF Yield for Septerna Inc (SEPN) as of Aug 15 2025?

What is the current Forward P/E ratio for Septerna Inc (SEPN) as of Aug 15 2025?
