SEPN Forecast — Price Prediction for 2025. Should I Buy SEPN?

1-Day-Price-Prediction

-1.87%

1-Week Prediction

-1.89%

1-Month Prediction

+6.89%

2026 Prediction

-100%

2030 Prediction

-100%

Based on our advanced algorithm, we have generated comprehensiveSEPN stock price predictions for multiple time horizons. Our models indicate potential volatility in the short term, with specific targets calculated for the 1-day and 1-week outlooks.

Looking further ahead, our analysts have pinpointed significant trend shifts in the longer-term data. We have exclusive projections available for the 1-month forecast, a detailed 2026 projection, and a long-range 2030 forecast that reveals potential upside or downside risks.

Unlock the full analysis to access these precise price targets and see exactly where our models predict SEPN is heading. Stay informed and make strategic decisions with our premium data-driven insights!

Should I Buy Septerna Inc Stock?

Based on our evaluation of the five key dimensions—Technical Signals, Moving Average trends, Short Sell Data, Similar Chart Pattern Matching and Seasonality Analysis—we have identified the following insights. SEPN has several positive signals and is within a rising trend, so we believe it will perform strongly in the next couple of days or weeks. We therefore hold a positive evaluation of this stock. Our analysis conclusion for this stock is a Strong Buy candidate.

SEPN stock price ended at $25.74 on Thursday, after losing -2.54%

The Septerna Inc stock price decreased by -2.54% on the last trading day (08 Jan 2026), dropping from 26.11 to 25.74. Throughout the last trading session, the stock experienced a fluctuation of 3.55% , ranging from a day low of $25.375 to a day high of 26.275. The price has declined in 6 of the last 10 days, resulting in a total change of -8.82% during this period. On the last day, trading volume increase by -127.28K shares, with the falling prices. This could serve as an early warning, indicating that risk may slightly increase in the coming days. In total, 177.61K shares were traded, amounting to approximately 4.59M.

SEPN Technical Signals

SEPN(Septerna Inc Corp) has 4 buy signals and 3 sell signals now. The current trend is a downtrend starting from 2025-12-19. The total price change during this trend is -12.98%. Recently, the price has dropped while volume droped, indicating a potential rebound signal. The average turnover of SEPN over the last 5 trading days is 6.80M. Overall, the technical indicator signals lean more toward a Neutral outlook in the mid-term.

SEPN Moving Average Analysis

Septerna Inc's overall moving average trend leans more bearish as of Friday, January 9, 2026, with 2 negative signals and 2 positive signal. In the mid-term, the SMA_20 being above the SMA_60 signals a strong bullish trend. There will be some resistance from the lines at $30.18, and $31.86. A break-up above any of these levels will issue buy signals. There will be some support from the lines at $24.72, and $23.03. A break-down below any of these levels will issue sell signals.

SEPN Short Selling Analysis

The short sale ratio of Septerna Inc(SEPN) as of 10 Dec 2025 is 15.78%, dropping from last trading day. With decreasing price from 25.49 to 25.64. The short sell activity indicate that short sellers may be experiencing short cover.

Technical Signal

Technical Signals Summary

Sell

Buy

Moving Average

Swing

Negative

Stock Price Below SMA_5

Short Term

Negative

SMA_5 Below SMA_20

Mid Term

Positive

SMA_20 Above SMA_60

Long Term

Positive

SMA_60 Above SMA_200

Short Selling

Close Price

Short Sale Ratio

Short Sale Volume

4 Bullish Signals

When Value satisfies Signal, Indicator signals Bullish

Indicators

Signal

Value

Meaning

Stochastic Oscillator %K (14, 3, 3)

STOCHk_14_3_3 < 20

11.914

Bullish

Moving Average Convergence Divergence (12, 26, 9)

MACD_12_26_9 > 0

0.33

Bullish

Stochastic RSI %K (14, 14, 3, 3)

STOCHRSIk_14_14_3_3 < 20

9.461

Bullish

Williams %R (14 days)

WILLR_14 < -80

-90.494

Bullish

3 Bearish Signals

When Value satisfies Signal, Indicator signals Bearish

Indicators

Signal

Value

Meaning

Awesome Oscillator (5, 34)

AO_5_34 < 0

-0.251

Bearish

Momentum (10 days)

MOM_10 < 0

-2.49

Bearish

Closing price

close < fibonacci_S1

25.74

Bearish

SEPN Stock Forecast

2026

2027

2028

2029

2030

2031

2032

2033

2034

2035

Month	Min. Price	Avg. Price	Max. Price	Potential ROI

In 2026, Septerna Inc (SEPN) is anticipated to change hands in a trading channel between $0.00 and $0.00.

Septerna Inc Stock Forecast 2026

SEPN Price Prediction & Forecast by Similar Chart Analysis

Based on historical patterns and backtesting of stocks with similar movements to Septerna Inc(SEPN), our algorithm predicts SEPN's 1-month price at $23.01, with an -17.75%downwardshift. Using a similarity score up to 93.48%and other factors, This forecast updates weekly, adjusting for significant deviations.

Similar Chart

The price prediction chart for Septerna Inc (SEPN.O) stock, as of Sunday, January 4, 2026 , forecasts a -17.75% change over the next month, based on its high correlation with KINS.O stock patterns. The similarity between their price movements over the analyzed periods is 93.48%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.

SEPN

No data

KINS

Down: -17.75%Similarity: 93.48%

Name

Similarity

Up/Down

KINS.O

93.48%

-17.75%

DRMA.O

93.10%

-4.10%

EFSC.O

92.57%

-10.55%

BBY.N

92.01%

+8.51%

INVE.O

91.69%

+5.14%

ARMP.A

91.67%

-34.13%

NVAX.O

91.55%

-75.80%

VTRS.O

91.20%

-22.75%

KWM.O

91.05%

+0.78%

BCC.N

90.40%

+3.79%

SEPN Seasonality Analysis

Based on SEPN's historical stock price data across all years, the probability of a positive return in January is0.00%, suggesting it maynotbe an ideal month to invest in SEPN. In contrast,Apriloffers the highest probability of positive returns at100.00%, making it a potentially strong month for investment.

However, this is only a prediction based on one method, and a comprehensive assessment of the stock's future trend should consider additional factors. Our final stock price commentary incorporates three main evaluation dimensions: technical signals, Moving Average trends, and similar chart pattern matching, with the first two dimensions carrying the primary weight to ensure a more robust and accurate forecast.

Monthly Seasonality

The radar chart shows that buying Septerna Inc (SEPN.O) stock in April has the highest probability of a positive return (100.00%), while January has the lowest probability (0.00%).

Performance Seasonality

The chart shows Septerna Inc. (SEPN)'s annual stock price return for the past three years, helping you analyze price trends and identify recurring trends on an annual basis.

People Also Watch

Frequently Asked Questions

Should I buy Septerna Inc (SEPN.O) stock?

Which months have the highest win rate for buying Septerna Inc (SEPN.O) stock in a year?

The radar chart shows that buying Septerna Inc (SEPN.O) stock in April has the highest probability of a positive return (100.00%), while January has the lowest probability (0.00%).

How has Septerna Inc. (SEPN)'s stock price performed over the past three years?

SEPN's stock price rose by 7.01% in 2024,increased by 30.59% in 2025, and went down by 8.01%in 2026.

Which bullish technical signals does SEPN have?

Bullish technical signals of SEPN include: STOCHk_14_3_3 < 20, MACD_12_26_9 > 0, STOCHRSIk_14_14_3_3 < 20, WILLR_14 < -80.

Which bearish technical signals does SEPN have?

Bearish technical signals of SEPN include: AO_5_34 < 0, MOM_10 < 0, close < fibonacci_S1.

Is SEPN a buy based on overall technical signals summary?

SEPN has 4 buy signals and 3 sell signals now. Overall the technical rating for SEPN is Neutral . Note that market conditions change all the time. In addition to technical ratings, keep an eye on the Valuation Level of SEPN.

What is the trend of Septerna Inc (SEPN)'s moving average?

Septerna Inc's overall moving average trend leans more bearish as of January 09 2026, with 2 negative signals and 2 positive signal.

What is price prediction for SEPN stock next month?

The price prediction chart for Septerna Inc (SEPN.O) stock, as of January 04 2026, forecasts a -17.75% change over the next month, based on its high correlation with KINS stock patterns. The similarity between their price movements over the analyzed periods is 93.48%. The right panel lists other stocks with similar price patterns. This prediction is updated every week.

What is price prediction 2026 for Septerna Inc (SEPN) Stock?

In , Septerna Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.

What is price prediction 2030 for Septerna Inc (SEPN) Stock?

In , Septerna Inc's value is forecasted to reach an average price of $NaN. The price is predicted to fluctuate between a low of $NaN and a high of $NaN.

SEPN Stock Price Prediction

SEPN Stock Price Prediction

Should I Buy Septerna Inc Stock?

SEPN stock price ended at $25.74 on Thursday, after losing -2.54%

SEPN Technical Signals

SEPN Moving Average Analysis

SEPN Short Selling Analysis

Technical Signal

Technical Signals Summary

Moving Average

Short Selling

SEPN Stock Forecast

SEPN Price Prediction & Forecast by Similar Chart Analysis

No data

SEPN Seasonality Analysis

Monthly Seasonality

Performance Seasonality

People Also Watch

Frequently Asked Questions

Should I buy Septerna Inc (SEPN.O) stock?

Which months have the highest win rate for buying Septerna Inc (SEPN.O) stock in a year?

How has Septerna Inc. (SEPN)'s stock price performed over the past three years?

Which bullish technical signals does SEPN have?

Which bearish technical signals does SEPN have?

Is SEPN a buy based on overall technical signals summary?

What is the trend of Septerna Inc (SEPN)'s moving average?

What is price prediction for SEPN stock next month?

What is price prediction 2026 for Septerna Inc (SEPN) Stock?

What is price prediction 2030 for Septerna Inc (SEPN) Stock?