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RVMD Overview

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0.000(0.000%)Aft-market
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0.000
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ET
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Intellectia

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High
135.150
Open
134.625
VWAP
134.02
Vol
989.42K
Mkt Cap
28.07B
Low
132.000
Amount
132.60M
EV/EBITDA(TTM)
--
Total Shares
208.74M
EV
26.37B
EV/OCF(TTM)
--
P/S(TTM)
--
Revolution Medicines, Inc. is a clinical-stage oncology company developing novel targeted therapies for RAS-addicted cancers. The Company’s research and development pipeline comprises RAS(ON) inhibitors that bind directly to RAS variants, which it refers to as RAS(ON) Inhibitors, and RAS companion inhibitors that target key nodes in the RAS pathway or associated pathways, which it refers to as RAS Companion Inhibitors. Its RAS(ON) Inhibitors are designed to be used as monotherapy, in combination with other RAS(ON) Inhibitors and/or in combination with RAS Companion Inhibitors or other therapeutic agents. The company’s RAS(ON) inhibitors are daraxonrasib (RMC-6236), an RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), an RAS(ON) G12C-selective inhibitor; and zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor, are in clinical development. The Company’s pipeline also focuses on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C).
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Events Timeline

(ET)
2026-04-19
16:30:00
Revolution Medicines Updates Zoldonrasib Clinical Data
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2026-04-15 (ET)
2026-04-15
05:50:00
Deal Size Increased to $1.5B
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2026-04-13 (ET)
2026-04-13
17:10:00
Revolution Medicines Files to Sell $250M of Convertible Senior Notes
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2026-04-13
17:10:00
Revolution Medicines Files to Sell $750M of Common Stock
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2026-04-13
16:40:00
Major Averages Rise as Oil Surges Past $100
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2026-04-13
12:10:00
Erasca Shares Drop 9% to $15.54 After Revolution Pancreatic Cancer Data
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News

NASDAQ.COM
9.0
04-22NASDAQ.COM
PinnedRevolution Medicines Updates Clinical Data on Daraxonrasib for Pancreatic Cancer
  • Clinical Trial Update: Revolution Medicines has updated clinical data from two Phase 1/2 trials of Daraxonrasib in previously untreated metastatic pancreatic ductal adenocarcinoma patients, demonstrating manageable safety and tolerability, supporting further evaluation in first-line treatment.
  • Combination Therapy Results: In the RMC-GI-102 trial, patients receiving Daraxonrasib combined with gemcitabine and nab-paclitaxel showed a confirmed objective response rate (ORR) of 58%, indicating significant antitumor activity, with a 6-month progression-free survival (PFS) estimate of 84%.
  • Monotherapy Performance: In the RMC-6236-001 trial, Daraxonrasib monotherapy yielded an ORR of 47% and a disease control rate of 92%, with a 6-month PFS estimate of 71%, highlighting its potential in treating previously untreated RAS-mutant metastatic pancreatic cancer patients.
  • Future Presentation Plans: The company plans to present the latest data from both the combination and monotherapy cohorts at the American Association for Cancer Research Annual Meeting on April 21, 2026, further validating the application prospects of Daraxonrasib in this high-mortality cancer.
Newsfilter
2.0
04-21Newsfilter
Revolution Medicines Releases Clinical Data on Daraxonrasib
  • Clinical Trial Updates: Revolution Medicines presented updated clinical data on daraxonrasib at the AACR Annual Meeting, demonstrating manageable safety and early signs of durable antitumor activity in previously untreated metastatic pancreatic ductal adenocarcinoma patients, supporting further evaluation in first-line treatment.
  • Combination Therapy Efficacy: In the RMC-GI-102 trial, 40 patients received daraxonrasib combined with gemcitabine and nab-paclitaxel, achieving a 58% objective response rate, indicating the potential of this combination in treating difficult-to-manage pancreatic cancer.
  • Monotherapy Performance: In the RMC-6236-001 trial, daraxonrasib monotherapy showed a 47% objective response rate and a 92% disease control rate, highlighting its effectiveness in previously untreated patients.
  • Future Research Directions: Daraxonrasib is currently being evaluated in four global Phase 3 clinical trials, showcasing its broad application potential in treating RAS-mutant cancers, particularly in pancreatic and non-small cell lung cancer.
Newsfilter
2.0
04-21Newsfilter
Revolution Medicines Presents Phase 3 Trial Results for Daraxonrasib
  • Clinical Trial Results: Revolution Medicines presented results from the RASolute 302 trial at the ASCO Annual Meeting, demonstrating that daraxonrasib significantly improved progression-free survival (PFS) and overall survival (OS) in patients with metastatic pancreatic ductal adenocarcinoma, thereby strengthening the company's competitive position in oncology.
  • Drug Design Advantages: As an oral RAS(ON) multi-selective inhibitor, daraxonrasib has received Breakthrough Therapy and Orphan Drug Designations from the FDA, indicating its potential value in treating patients with specific RAS mutations, which may attract increased investor interest.
  • Global Clinical Reach: The RASolute 302 trial enrolled patients globally, covering a range of RAS variants, showcasing the company's capability to expand in international markets, with successful clinical outcomes likely to drive drug approval and enhance market share.
  • Future Growth Potential: With daraxonrasib being evaluated in additional clinical trials, Revolution Medicines' R&D pipeline indicates strong growth potential, particularly in the treatment of RAS-mutant cancers, which could lead to long-term revenue growth for the company.
Newsfilter
9.0
04-19Newsfilter
Revolution Medicines Releases Updated Clinical Data for Zoldonrasib
  • Clinical Trial Progress: Revolution Medicines presented updated Phase 1 clinical data for zoldonrasib at the AACR Annual Meeting, involving 40 patients with KRAS G12D non-small cell lung cancer, demonstrating a 52% objective response rate, indicating significant clinical activity and potential new treatment options for patients.
  • Safety Analysis: Among patients treated with 1200 mg of zoldonrasib once daily, 43% experienced nausea, 33% vomiting, and 30% diarrhea, with most adverse events being Grade 1, showcasing a favorable safety profile that supports further clinical development.
  • Survival Rate Data: The treatment yielded an 11.1-month median progression-free survival and a 73% 12-month survival rate among treated patients, suggesting zoldonrasib's potential efficacy in KRAS G12D non-small cell lung cancer, which could alter the treatment landscape in this area.
  • Market Potential: With approximately 61,000 new patients diagnosed with RAS G12D cancers annually, the development of zoldonrasib not only addresses significant unmet medical needs but also presents substantial commercial opportunities for Revolution Medicines in the competitive oncology market.
Newsfilter
8.5
04-17Newsfilter
Revolution Medicines Closes Upsized Offering of 12.1 Million Shares
  • Significant Financing: Revolution Medicines successfully completed an upsized offering of 12,147,887 shares of common stock at $142 per share, generating approximately $2.225 billion in gross proceeds, reflecting strong market confidence in its targeted therapies for RAS-addicted cancers.
  • Convertible Notes Issuance: The company also issued $500 million in 0.50% convertible senior notes due 2033, with an initial conversion price of about $198.80, representing a 40% premium over the offering price, providing flexibility for future financing.
  • Clear Use of Proceeds: The estimated net proceeds of approximately $2.137 billion will be allocated to research and development, potential commercialization of product candidates, and general corporate expenses, indicating the company's commitment to future product development and strategic planning.
  • Positive Market Reaction: The offering was facilitated by prominent investment banks like J.P. Morgan, reflecting investor optimism about Revolution Medicines' prospects in oncology, which may drive an increase in the company's stock price.
seekingalpha
8.5
04-15seekingalpha
Revolution Medicines Raises Approximately $1.5 Billion in Public Offering
  • Upsized Offering: Revolution Medicines successfully priced a public offering of 10.56 million shares at $142 each, raising approximately $1.5 billion, significantly up from the initial plan of $750 million, indicating strong market demand for its stock.
  • Convertible Notes Issuance: The company also issued $500 million in convertible senior notes with a 0.50% annual interest rate, maturing on May 1, 2033, which is expected to provide additional funding to support R&D and commercialization efforts.
  • Conversion Price Premium: The initial conversion price of approximately $198.80 represents a 40% premium over the public offering price, reflecting investor confidence in the company's growth potential and likely attracting more investor interest.
  • Clear Use of Proceeds: Revolution Medicines plans to utilize the raised funds for general corporate purposes, including R&D, potential commercialization, administrative costs, and capital expenditures, demonstrating a clear strategic plan for future growth.
Wall Street analysts forecast RVMD stock price to rise
20 Analyst Rating
Wall Street analysts forecast RVMD stock price to rise
20 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
67.00
Averages
86.00
High
147.00
Current: 0.000
sliders
Low
67.00
Averages
86.00
High
147.00
Evercore ISI
NULL
to
Outperform
maintain
$140 -> $200
AI Analysis
2026-04-14
Reason
Evercore ISI
Price Target
$140 -> $200
AI Analysis
2026-04-14
maintain
NULL
to
Outperform
Reason
Evercore ISI raised the firm's price target on Revolution Medicines to $200 from $140 and keeps an Outperform rating on the shares. Daraxonrasib's RASolute 302 readout is "a true game-changer" with a "stunning OS benefit" that accelerates timelines across the board, says the analyst, who now bakes in an earlier launch, bigger peak sales, and a higher probability of success in pancreatic ductal adenocarcinoma.
Guggenheim
Buy
upgrade
$160 -> $175
2026-04-14
Reason
Guggenheim
Price Target
$160 -> $175
2026-04-14
upgrade
Buy
Reason
Guggenheim raised the firm's price target on Revolution Medicines to $175 from $160 and keeps a Buy rating on the shares after the company announced that RASolute 302, the first Phase 3 study of daraxonrasib, met all primary and key secondary endpoints at the first interim analysis. The firm expects rapid uptake of daraxonrasib in second-line pancreatic ductal adenocarcinoma and believes the result also further de-risks potential future label expansion into first-line metastatic and adjuvant PDAC, the analyst tells investors.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for RVMD
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Valuation Metrics

The current forward P/E ratio for Revolution Medicines Inc (RVMD.O) is 0.00, compared to its 5-year average forward P/E of -8.74. For a more detailed relative valuation and DCF analysis to assess Revolution Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-8.74
Current PE
0.00
Overvalued PE
-6.31
Undervalued PE
-11.16

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-6.22
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
-4.32
Undervalued EV/EBITDA
-8.13

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
2477.83
Current PS
48.02
Overvalued PS
8106.06
Undervalued PS
-3150.41

Financials

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Whales Holding RVMD

J
Janus Henderson Group plc
Holding
RVMD
+42.94%
3M Return
P
Polar Capital Holdings Plc
Holding
RVMD
+27.24%
3M Return
H
Hood River Capital Management LLC
Holding
RVMD
+24.43%
3M Return
B
Boothbay Fund Management, LLC
Holding
RVMD
+17.99%
3M Return
A
Artal Group S.A.
Holding
RVMD
+14.84%
3M Return
P
Paradigm Biocapital Advisors LP
Holding
RVMD
+13.55%
3M Return

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Frequently Asked Questions

What is Revolution Medicines Inc (RVMD) stock price today?

The current price of RVMD is 134.91 USD — it has increased 0.32

What is Revolution Medicines Inc (RVMD)'s business?

Revolution Medicines, Inc. is a clinical-stage oncology company developing novel targeted therapies for RAS-addicted cancers. The Company’s research and development pipeline comprises RAS(ON) inhibitors that bind directly to RAS variants, which it refers to as RAS(ON) Inhibitors, and RAS companion inhibitors that target key nodes in the RAS pathway or associated pathways, which it refers to as RAS Companion Inhibitors. Its RAS(ON) Inhibitors are designed to be used as monotherapy, in combination with other RAS(ON) Inhibitors and/or in combination with RAS Companion Inhibitors or other therapeutic agents. The company’s RAS(ON) inhibitors are daraxonrasib (RMC-6236), an RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), an RAS(ON) G12C-selective inhibitor; and zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor, are in clinical development. The Company’s pipeline also focuses on RAS(ON) mutant-selective inhibitors, including RMC-0708 (Q61H) and RMC-8839 (G13C).

What is the price predicton of RVMD Stock?

Wall Street analysts forecast RVMD stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for RVMD is86.00 USD with a low forecast of 67.00 USD and a high forecast of 147.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Revolution Medicines Inc (RVMD)'s revenue for the last quarter?

Revolution Medicines Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Revolution Medicines Inc (RVMD)'s earnings per share (EPS) for the last quarter?

Revolution Medicines Inc. EPS for the last quarter amounts to -1.88 USD, increased 67.86

How many employees does Revolution Medicines Inc (RVMD). have?

Revolution Medicines Inc (RVMD) has 883 emplpoyees as of April 24 2026.

What is Revolution Medicines Inc (RVMD) market cap?

Today RVMD has the market capitalization of 28.07B USD.