
PLRX
Pliant Therapeutics Inc
- Overview
- Forecast
- Valuation

Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
1.370
Open
1.340
VWAP
1.34
Vol
248.05K
Mkt Cap
83.79M
Low
1.325
Amount
332.83K
EV/EBITDA(TTM)
--
Total Shares
60.33M
EV
-191.88M
EV/OCF(TTM)
--
P/S(TTM)
--
Pliant Therapeutics, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on discovering and developing therapies for the treatment of fibrosis and related diseases. It focuses in treating fibrosis by inhibiting integrin-mediated activation of transforming growth factor beta (TGF-B). Its lead product candidate, bexotegrast (PLN-74809), is an oral small-molecule, dual-selective inhibitor of avß6 and avB1. Its second product candidate, PLN-1474, is a small-molecule, selective inhibitor of avB1 for treatment of liver fibrosis associated with nonalcoholic steatohepatitis. In addition to its clinical programs, it is developing additional preclinical integrin-based programs targeting muscular dystrophies. It is also developing PLN-101095 an oral, dual inhibitor of αvß8 and αvß1 integrins for the treatment of solid tumors. Its clinical programs also include PLN-101325, an allosteric agonistic monoclonal antibody against α7β1 for treatment of muscular dystrophies.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q2
FY2025Q3
FY2025Q4
--
--
-0.659
-28.32%
--
--
-0.482
-49.29%
--
--
-0.428
-47.85%
Estimates Revision
The market is revising Upward the revenue expectations for Pliant Therapeutics, Inc. (PLRX) for FY2025, with the revenue forecasts being adjusted by 113.89% over the past three months. During the same period, the stock price has changed by -54.19%.
Revenue Estimates for FY2025
Revise Upward

+113.89%
In Past 3 Month
EPS Estimates for FY2025
Revise Downward

-39.6%
In Past 3 Month
Stock Price
Go Down

-54.19%
In Past 3 Month
13 Analyst Rating

284.62% Upside
Wall Street analysts forecast PLRX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PLRX is 5.25 USD with a low forecast of 1.50 USD and a high forecast of 17.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
2 Buy
11 Hold
0 Sell
Hold

284.62% Upside
Current: 1.365

Low
1.50
Averages
5.25
High
17.00

284.62% Upside
Current: 1.365

Low
1.50
Averages
5.25
High
17.00
HC Wainwright & Co.
Ed Arce
Hold
Reiterates
n/a
2025-03-18
Reason
HC Wainwright & Co.
Ed Arce
Price Target
n/a
2025-03-18
Reiterates
Hold
Reason
Needham
Joseph Stringer
Strong Buy
to
Hold
Downgrades
$10
2025-03-04
Reason
Needham
Joseph Stringer
Price Target
$10
2025-03-04
Downgrades
Strong Buy
to
Hold
Reason
Wells Fargo
Tiago Fauth
Hold
Maintains
$4 → $3
2025-03-04
Reason
Wells Fargo
Tiago Fauth
Price Target
$4 → $3
2025-03-04
Maintains
Hold
Reason
Cantor Fitzgerald
Pete Stavropoulos
Hold
Initiates
n/a
2025-03-04
Reason
Cantor Fitzgerald
Pete Stavropoulos
Price Target
n/a
2025-03-04
Initiates
Hold
Reason
Cantor Fitzgerald reinstated coverage of Pliant Therapeutics with a Neutral rating and no price target. The company is discontinuing the Pase 2b BEACON-IPF study of bexotegrast in idiopathic pulmonary fibrosis, the analyst tells investors in a research note. The firm says that while Pliant has two additional clinical stage programs and a third Phase 1-ready asset, without clear visibility on program prioritization, it remains on the sidelines.
RBC Capital
Brian Abrahams
Hold
Maintains
$4 → $3
2025-03-04
Reason
RBC Capital
Brian Abrahams
Price Target
$4 → $3
2025-03-04
Maintains
Hold
Reason
Citigroup
David Lebowitz
Hold
Maintains
$4 → $1.5
2025-03-04
Reason
Citigroup
David Lebowitz
Price Target
$4 → $1.5
2025-03-04
Maintains
Hold
Reason
Citi lowered the firm's price target on Pliant Therapeutics to $1.50 from $4 and keeps a Neutral rating on the shares. The company reported Q4 earnings after announcing it had discontinued the Phase 2b BEACON-IPF trial for bexotegrast in idiopathic pulmonary fibrosis after an outside expert panel completed an secondary review and concurred with the Data Safety Monitoring Board's recommendation, the analyst tells investors in a research note. Post the update, Citi substantially reduce its bexotegrast estimates, delaying a timeline of potential launch and lowering its probability of success to 20% from 40%.
See All Ratings
Valuation Metrics
The current forward P/E ratio for Pliant Therapeutics Inc (PLRX.O) is -0.64, compared to its 5-year average forward P/E of -5.77. For a more detailed relative valuation and DCF analysis to assess Pliant Therapeutics Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
-5.77
Current PE
-0.64
Overvalued PE
-2.71
Undervalued PE
-8.83
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-2.78
Current EV/EBITDA
1.22
Overvalued EV/EBITDA
0.19
Undervalued EV/EBITDA
-5.75
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

Fair
5Y Average PS
307.90
Current PS
46.59
Overvalued PS
592.80
Undervalued PS
22.99
Financials
Annual
Quarterly
FY2025Q1
0.00
Total Revenue
FY2025Q1
YoY :
+12.49%
-58.94M
Operating Profit
FY2025Q1
YoY :
+19.62%
-56.17M
Net Income after Tax
FY2025Q1
YoY :
+17.95%
-0.92
EPS - Diluted
FY2025Q1
YoY :
+54.66%
-49.13M
Free Cash Flow
FY2025Q1
N/A
Gross Profit Margin - %
FY2025Q1
YoY :
-100.00%
N/A
FCF Margin - %
FY2025Q1
N/A
Net Margin - %
Trading Trends
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
1.5M
USD
7
6-9
Months
0.0
USD
0
0-12
Months
919.0K
USD
5
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds areBuying! The buying amount has increased 193.24% over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
690.7K
Volume
3
6-9
Months
0.0
Volume
0
0-12
Months
267.6K
Volume
2
Bought
0-3
0
0.0
Volume
Months
3-6
3
2.0M
Volume
Months
6-9
0
0.0
Volume
Months
0-12
4
669.3K
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
1.5M
USD
7
6-9
Months
0.0
USD
0
0-12
Months
919.0K
USD
5
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
PLRX News & Events
Events Timeline
2025-05-08 (ET)
2025-05-08
17:41:04
Pliant Therapeutics reports Q1 EPS (92c), consensus (62c)

2025-05-08
16:41:51
Pliant Therapeutics reports Q1 EPS (92c), consensus (75c)

2025-05-01 (ET)
2025-05-01
16:56:39
Pliant Therapeutics to reduce workforce by 45%

Sign Up For More Events
Sign Up For More Events
News
4.5
05-01NewsfilterPliant Therapeutics Announces Strategic Realignment of Workforce and Operations
7.0
04-25GlobenewswireINVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Pliant Therapeutics, Inc. – PLRX
7.0
04-21GlobenewswireINVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Pliant Therapeutics, Inc. - PLRX
Sign Up For More News
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FAQ

What is Pliant Therapeutics Inc (PLRX) stock price today?
The current price of PLRX is 1.365 USD — it has increased 0.37 % in the last trading day.

What is Pliant Therapeutics Inc (PLRX)'s business?

What is the price predicton of PLRX Stock?

What is Pliant Therapeutics Inc (PLRX)'s revenue for the last quarter?

What is Pliant Therapeutics Inc (PLRX)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for Pliant Therapeutics Inc (PLRX)'s fundamentals?

How many employees does Pliant Therapeutics Inc (PLRX). have?
