
Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
1.300
Open
1.260
VWAP
1.24
Vol
460.11K
Mkt Cap
73.72M
Low
1.180
Amount
569.09K
EV/EBITDA(TTM)
--
Total Shares
58.89M
EV
-48.78M
EV/OCF(TTM)
--
P/S(TTM)
4.56
Pyxis Oncology, Inc. is a clinical-stage company focused on developing therapeutics to target difficult-to-treat cancers. The Company is building therapeutics that hold the potential for mono and combination therapies. Its clinical program portfolio includes PYX-201, PYX-106 and PYX-107. PYX-201, an antibody-drug conjugate (ADC) that targets Extradomain-B Fibronectin within the tumor stroma, and PYX-106, a fully human Siglec-15-targeting antibody designed to block suppression of T-cell proliferation and function, are being evaluated in ongoing Phase 1 clinical studies in multiple types of solid tumors. PYX-107 is a CD40 agonist antibody designed to maximize its agonistic properties. Its therapeutic candidates are designed to directly kill tumor cells and to address the underlying pathologies created by cancer that enable its uncontrollable proliferation and immune evasion. Its ADC and immuno-oncology (IO) programs target a range of solid tumors resistant to current standards of care.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q3
FY2025Q2
FY2025Q1
--
--
-0.297
-15.24%
--
--
-0.297
+2.3%
--
--
-0.300
+400%
Estimates Revision
The market is revising No Change the revenue expectations for Pyxis Oncology, Inc. (PYXS) for FY2025, with the revenue forecasts being adjusted by 0% over the past three months. During the same period, the stock price has changed by -19.05%.
Revenue Estimates for FY2025
No Change

0.00%
In Past 3 Month
EPS Estimates for FY2025
Revise Downward

-9.19%
In Past 3 Month
Stock Price
Go Down

-19.05%
In Past 3 Month
7 Analyst Rating

509.24% Upside
Wall Street analysts forecast PYXS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PYXS is 7.25 USD with a low forecast of 5.00 USD and a high forecast of 10.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
6 Buy
1 Hold
0 Sell
Strong Buy

509.24% Upside
Current: 1.190

Low
5.00
Averages
7.25
High
10.00

509.24% Upside
Current: 1.190

Low
5.00
Averages
7.25
High
10.00
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$5
2025-03-19
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$5
2025-03-19
Reiterates
Strong Buy
Reason
RBC Capital
Leonid Timashev
Buy
Reiterates
$8
2025-03-19
Reason
RBC Capital
Leonid Timashev
Price Target
$8
2025-03-19
Reiterates
Buy
Reason
RBC Capital
Leonid Timashev
Buy
Reiterates
$10 → $8
2024-12-20
Reason
RBC Capital
Leonid Timashev
Price Target
$10 → $8
2024-12-20
Reiterates
Buy
Reason
RBC Capital analyst Leonid Timashev lowered the firm's price target on Pyxis Oncology to $8 from $10 and keeps an Outperform rating on the shares. The company's pipeline update to prioritize PYX-201 over further investment in PYX-106 is "prudent" given the early signs of activity and the operating expense savings that will be leveraged to continue to advance PYX-201 development, though the firm is reducing its price target on lower "pipeline optionality", the analyst tells investors in a research note.
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$7 → $5
2024-12-20
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$7 → $5
2024-12-20
Reiterates
Strong Buy
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$7
2024-11-21
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$7
2024-11-21
Reiterates
Strong Buy
Reason
William Blair
Andy Hsieh
Buy
to
Hold
Downgrades
n/a
2024-11-21
Reason
William Blair
Andy Hsieh
Price Target
n/a
2024-11-21
Downgrades
Buy
to
Hold
Reason
William Blair analyst Andy Hsieh downgraded Pyxis Oncology to Market Perform from Outperform.
See All Ratings
Valuation Metrics
The current forward P/E ratio for Pyxis Oncology Inc (PYXS.O) is -0.99, compared to its 5-year average forward P/E of -1.97. For a more detailed relative valuation and DCF analysis to assess Pyxis Oncology Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
-1.97
Current PE
-0.99
Overvalued PE
-0.33
Undervalued PE
-3.60
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-0.20
Current EV/EBITDA
0.22
Overvalued EV/EBITDA
1.51
Undervalued EV/EBITDA
-1.91
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

N/A
5Y Average PS
78.70
Current PS
0.00
Overvalued PS
239.48
Undervalued PS
-82.08
Financials
Annual
Quarterly
FY2024Q4
0.00
Total Revenue
FY2024Q4
YoY :
+7.53%
-19.11M
Operating Profit
FY2024Q4
YoY :
+128.06%
-35.57M
Net Income after Tax
FY2024Q4
YoY :
+65.71%
-0.58
EPS - Diluted
FY2024Q4
YoY :
+26.46%
-19.29M
Free Cash Flow
FY2024Q4
97.06
Gross Profit Margin - %
FY2024Q4
-358.66
FCF Margin - %
FY2024Q4
-478.95
Net Margin - %
Trading Trends
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
1
174.4K
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
320.0K
Volume
1
6-9
Months
0.0
Volume
0
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
1
1.1M
Volume
Months
6-9
0
0.0
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
1
174.4K
USD
Months
0-12
0
0.0
USD
Months
PYXS News & Events
Events Timeline
2025-03-18 (ET)
2025-03-18
07:32:31
Pyxis Oncology reports FY24 EPS ($1.32), consensus ($1.09)

2025-02-26 (ET)
2025-02-26
07:34:31
Pyxis Oncology granted Fast Track designation for PYX-201 monotherapy

2024-12-19 (ET)
2024-12-19
15:17:10
Pyxis Oncology to prioritize PYX-201, suspends investment in PYX-106

Sign Up For More Events
Sign Up For More Events
News
1.0
04-02NewsfilterPyxis Oncology to Participate in the Stifel 2025 Virtual Targeted Oncology Forum
9.0
03-25NewsfilterPyxis Oncology to Present New Preclinical Data Supporting Development of First-In-Concept ADC Targeting EDB+FN in Tumor Microenvironment at AACR 2025
4.0
03-19Business InsiderRBC Capital Remains a Buy on Pyxis Oncology (PYXS)
Sign Up For More News
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FAQ

What is Pyxis Oncology Inc (PYXS) stock price today?
The current price of PYXS is 1.19 USD — it has decreased -5.56 % in the last trading day.

What is Pyxis Oncology Inc (PYXS)'s business?

What is the price predicton of PYXS Stock?

What is Pyxis Oncology Inc (PYXS)'s revenue for the last quarter?

What is Pyxis Oncology Inc (PYXS)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for Pyxis Oncology Inc (PYXS)'s fundamentals?

How many employees does Pyxis Oncology Inc (PYXS). have?
