
PYXS
Pyxis Oncology Inc
- Overview
- Forecast
- Valuation
- Earnings

Line
|

Candle
1D
5D
1M
3M
6M
YTD
1Y
5Y
High
1.165
Open
1.140
VWAP
1.14
Vol
143.07K
Mkt Cap
70.00M
Low
1.130
Amount
163.12K
EV/EBITDA(TTM)
--
Total Shares
58.89M
EV
-35.35M
EV/OCF(TTM)
--
P/S(TTM)
--
Pyxis Oncology, Inc. is a clinical-stage company focused on developing therapeutics to target difficult-to-treat cancers. The Company is building therapeutics that hold the potential for mono and combination therapies. Its clinical program portfolio includes micvotobart pelidotin (MICVO), PYX-106, Sotigalimab (PYX-107), PYX-203, PYX-102, and APX601. The Company’s lead product candidate, MICVO, is an antibody-drug conjugate (ADC) that targets Extradomain-B Fibronectin (EDB+FN), a non-cellular structural component of the tumor extra-cellular matrix (ECM). MICVO is designed to generate a multi-pronged attack on difficult-to-treat cancers by directly killing cancer cells, reducing ECM density, inhibiting tumor angiogenesis and mobilizing an anti-tumor immune response. The Company’s ADC, MICVO, consists of human Immunoglobulin G1 (IgG1) and is site-specifically conjugated with a cleavable linker and a microtubule inhibitor (optimized auristatin) payload.
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Market Estimates
Earnings Estimates
Revenue
YoY Chg
EPS
YoYChg
FY2025Q4
FY2025Q3
FY2025Q2
--
--
-0.337
+28.4%
--
--
-0.350
-0%
--
--
-0.352
+21.27%
Estimates Revision
The market is revising No Change the revenue expectations for Pyxis Oncology, Inc. (PYXS) for FY2025, with the revenue forecasts being adjusted by 0% over the past three months. During the same period, the stock price has changed by 4.63%.
Revenue Estimates for FY2025
No Change

0.00%
In Past 3 Month
EPS Estimates for FY2025
Revise Upward

+21.39%
In Past 3 Month
Stock Price
Go Up

+4.63%
In Past 3 Month
4 Analyst Rating

490.27% Upside
Wall Street analysts forecast PYXS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PYXS is 6.67 USD with a low forecast of 5.00 USD and a high forecast of 8.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.
3 Buy
1 Hold
0 Sell
Strong Buy

490.27% Upside
Current: 1.130

Low
5.00
Averages
6.67
High
8.00

490.27% Upside
Current: 1.130

Low
5.00
Averages
6.67
High
8.00
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$5
2025-03-19
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$5
2025-03-19
Reiterates
Strong Buy
Reason
RBC Capital
Leonid Timashev
Buy
Reiterates
$8
2025-03-19
Reason
RBC Capital
Leonid Timashev
Price Target
$8
2025-03-19
Reiterates
Buy
Reason
RBC Capital
Leonid Timashev
Buy
Reiterates
$10 → $8
2024-12-20
Reason
RBC Capital
Leonid Timashev
Price Target
$10 → $8
2024-12-20
Reiterates
Buy
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$7 → $5
2024-12-20
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$7 → $5
2024-12-20
Reiterates
Strong Buy
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Strong Buy
Reiterates
$7
2024-11-21
Reason
HC Wainwright & Co.
Swayampakula Ramakanth
Price Target
$7
2024-11-21
Reiterates
Strong Buy
Reason
William Blair
Andy Hsieh
Buy
to
Hold
Downgrades
n/a
2024-11-21
Reason
William Blair
Andy Hsieh
Price Target
n/a
2024-11-21
Downgrades
Buy
to
Hold
Reason
William Blair analyst Andy Hsieh downgraded Pyxis Oncology to Market Perform from Outperform.
See All Ratings
Valuation Metrics
The current forward P/E ratio for Pyxis Oncology Inc (PYXS.O) is -0.81, compared to its 5-year average forward P/E of -1.91. For a more detailed relative valuation and DCF analysis to assess Pyxis Oncology Inc 's fair value, click here.
Forward PE
The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.

N/A
5Y Average PE
-1.91
Current PE
-0.81
Overvalued PE
-0.30
Undervalued PE
-3.53
Forward EV/EBITDA
The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.

N/A
5Y Average EV/EBITDA
-0.19
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.48
Undervalued EV/EBITDA
-1.86
Forward PS
The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.

N/A
5Y Average PS
75.02
Current PS
0.00
Overvalued PS
232.86
Undervalued PS
-82.83
Financials
Annual
Quarterly
FY2025Q1
YoY :
-100.00%
0.00
Total Revenue
FY2025Q1
YoY :
+308.81%
-22.91M
Operating Profit
FY2025Q1
YoY :
+549.82%
-21.16M
Net Income after Tax
FY2025Q1
YoY :
+483.33%
-0.35
EPS - Diluted
FY2025Q1
YoY :
+7.58%
-22.54M
Free Cash Flow
FY2025Q1
YoY :
-100.00%
N/A
Gross Profit Margin - %
FY2025Q1
N/A
FCF Margin - %
FY2025Q1
YoY :
-100.00%
N/A
Net Margin - %
Trading Trends
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
1
174.4K
USD
Months
0-12
0
0.0
USD
Months
Hedge Fund
Hedge Funds are Neutral. There are no significant trading trends over the last quarter.
Sold
0-3
Months
0.0
Volume
0
3-6
Months
0.0
Volume
0
6-9
Months
320.0K
Volume
1
0-12
Months
0.0
Volume
0
Bought
0-3
0
0.0
Volume
Months
3-6
0
0.0
Volume
Months
6-9
1
1.1M
Volume
Months
0-12
0
0.0
Volume
Months
Congress Trading
Congress are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
0
0.0
USD
Months
0-12
0
0.0
USD
Months
Insider
Insiders are Neutral. There are no significant trading trends over the last month.
Sold
0-3
Months
0.0
USD
0
3-6
Months
0.0
USD
0
6-9
Months
0.0
USD
0
0-12
Months
0.0
USD
0
Bought
0-3
0
0.0
USD
Months
3-6
0
0.0
USD
Months
6-9
1
174.4K
USD
Months
0-12
0
0.0
USD
Months
PYXS News & Events
Events Timeline
2025-07-08 (ET)
2025-07-08
07:32:32
Crescent Biopharma appoints Jan Pinkas as CSO

2025-05-15 (ET)
2025-05-15
07:03:03
Pyxis Oncology reports Q1 EPS (35c), consensus (30c)

2025-03-18 (ET)
2025-03-18
07:32:31
Pyxis Oncology reports FY24 EPS ($1.32), consensus ($1.09)

Sign Up For More Events
Sign Up For More Events
News
5.0
06-30NewsfilterPyxis Oncology Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
4.0
05-19BenzingaHC Wainwright & Co. Reiterates Buy on Pyxis Oncology, Maintains $5 Price Target
1.0
04-02NewsfilterPyxis Oncology to Participate in the Stifel 2025 Virtual Targeted Oncology Forum
Sign Up For More News
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FAQ

What is Pyxis Oncology Inc (PYXS) stock price today?
The current price of PYXS is 1.13 USD — it has increased 0 % in the last trading day.

What is Pyxis Oncology Inc (PYXS)'s business?

What is the price predicton of PYXS Stock?

What is Pyxis Oncology Inc (PYXS)'s revenue for the last quarter?

What is Pyxis Oncology Inc (PYXS)'s earnings per share (EPS) for the last quarter?

What changes have occurred in the market's expectations for Pyxis Oncology Inc (PYXS)'s fundamentals?

How many employees does Pyxis Oncology Inc (PYXS). have?
