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MGNX Overview

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ET
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Intellectia

Loading chart...

High
3.055
Open
3.000
VWAP
2.98
Vol
891.05K
Mkt Cap
187.50M
Low
2.930
Amount
2.65M
EV/EBITDA(TTM)
--
Total Shares
63.56M
EV
70.77M
EV/OCF(TTM)
--
P/S(TTM)
1.27
MacroGenics, Inc. is a biopharmaceutical company focused on discovering, developing, manufacturing and commercializing monoclonal antibody-based therapeutics for the treatment of cancer. The Company generates its pipeline of product candidates primarily from its suite of antibody-based technology platforms, which have applicability across broad therapeutic domains. It is advancing three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload. Its other product candidates are MGD024, retifanlimab, enoblituzumab, and vobramitamab duocarmazine. MGD024 is an investigational, next-generation, bispecific CD123 CD3 DART molecule designed to engage CD3 expressed on immune effector cells, such as T cells.
Show More

Events Timeline

(ET)
2026-05-11
17:30:00
MacroGenics Sells GMP Drug Operations to Bora for $122.5M
select
2026-05-11
16:30:00
MacroGenics Trading Halted, News Pending
select
2026-05-04 (ET)
2026-05-04
07:50:00
MacroGenics Expands Royalty Purchase Agreement with Sagard
select
2026-04-08 (ET)
2026-04-08
16:40:00
MacroGenics LINNET Study Partially Lifted by FDA
select
2026-02-23 (ET)
2026-02-23
18:20:00
MacroGenics Faces Partial Clinical Hold on LINNET Study
select

News

seekingalpha
8.5
01:43 AMseekingalpha
MacroGenics Sells GMP Drug Manufacturing to Bora for $122.5 Million
  • Transaction Value: MacroGenics has agreed to sell its GMP drug manufacturing operations to Bora Pharmaceuticals for $122.5 million, providing non-dilutive capital to support the development of its cancer drug pipeline.
  • Employee Transition: The deal includes manufacturing facilities in Rockville and Frederick, Maryland, with approximately 140 employees expected to join Bora, thereby enhancing its North American biologics manufacturing capabilities.
  • Timeline for Closure: The transaction is expected to close in the third quarter of 2026, subject to customary conditions, allowing both parties ample time for integration and planning.
  • Strategic Implications: By divesting this segment, MacroGenics can focus resources on cancer drug development while optimizing its business structure and improving overall operational efficiency.
Newsfilter
8.5
05-11Newsfilter
MacroGenics Enters $122.5 Million Agreement with Bora Pharmaceuticals
  • Significant Transaction Value: MacroGenics has entered into an agreement with Bora Pharmaceuticals, which will provide an upfront payment of $122.5 million upon closing, aimed at accelerating MacroGenics' innovative drug pipeline to achieve key value inflection points in 2026.
  • Manufacturing Capability Transfer: The deal includes the transfer of MacroGenics' GMP drug manufacturing facility in Maryland and approximately 140 employees to Bora, enhancing Bora's operational capacity in the North American biopharmaceutical sector and improving its market competitiveness.
  • Strategic Integration: Bora plans to integrate this manufacturing site into its global CDMO operations, aiming to establish itself as the partner of choice for end-to-end clinical and commercial production in the biopharmaceutical industry, thereby driving its business growth.
  • Ongoing Collaborative Relationship: After the transaction closes, MacroGenics will maintain a supply agreement with Bora to support its internal pipeline development and production needs, ensuring a seamless transition and continued collaboration between the two companies.
seekingalpha
7.5
05-04seekingalpha
MacroGenics Expands Royalty Purchase Agreement with Sagard Healthcare Partners
  • Agreement Value: MacroGenics' expanded royalty purchase agreement with Sagard Healthcare Partners provides an upfront payment of $60 million and potential additional sales-based milestone payments of up to $20 million in 2026, enhancing the company's cash flow and financial flexibility.
  • Sales Rights Structure: The amended agreement grants Sagard a capped royalty interest in future global net sales of ZYNYZ, with expected returns of 1.7 times its investment by September 2032 and 2.0 times thereafter, offering MacroGenics long-term revenue potential.
  • Product Background: ZYNYZ, a PD-1 inhibitor, was originally developed by MacroGenics and licensed to Incyte Corporation under a global collaboration agreement, highlighting MacroGenics' ongoing innovation in the oncology sector.
  • Market Outlook: The agreement not only provides financial support to MacroGenics but also has the potential to accelerate the market introduction of ZYNYZ, further solidifying its position in the competitive oncology treatment market.
Newsfilter
7.5
05-04Newsfilter
MacroGenics Expands Royalty Agreement with Sagard for ZYNYZ
  • Expanded Royalty Agreement: MacroGenics has entered into an expanded royalty purchase agreement with Sagard, receiving a $60 million upfront payment and the potential for an additional $20 million sales-based milestone in 2026, thereby enhancing the company's liquidity and future growth potential.
  • Background on ZYNYZ: ZYNYZ (retifanlimab-dlwr) is a PD-1 inhibitor originally developed by MacroGenics and licensed to Incyte in 2017, indicating the company's ongoing innovation and competitive position in cancer treatment.
  • Retention of Economic Interests: Despite the royalty transfer to Sagard, MacroGenics retains other economic interests related to ZYNYZ, including future development, regulatory, and commercial milestones, which secures potential revenue growth for the company.
  • Investment Return Mechanism: Under the agreement, Sagard must achieve a 1.7x return on its investment by September 30, 2032, or a 2.0x return thereafter, ensuring MacroGenics' revenue rights revert back, thus enhancing its financial stability.
stocktwits
8.5
04-10stocktwits
MGNX Positioned for Growth in Antibody-Drug Conjugate Market
  • FDA Lifts Clinical Hold: MGNX announced that the U.S. FDA has lifted the partial clinical hold on its Phase 2 trial of Lorigerlimab, allowing the study to resume enrolling patients with advanced ovarian and gynecologic cancers, which is expected to accelerate clinical progress and patient recruitment.
  • Significant Stock Surge: Following a bullish analyst call, MGNX shares surged approximately 10% on Friday, reaching their highest levels since November 2024, indicating strong market confidence in the company's growth potential, with a year-to-date increase of around 133%.
  • Analyst Upgrade: B. Riley upgraded MGNX from ‘Neutral’ to ‘Buy’ with a price target of $9, driven by optimistic projections for the Antibody-Drug Conjugate (ADC) market, asserting that MGNX is uniquely positioned in the emerging “ADAM9 TOPO1i ADC” space.
  • Shift in Market Sentiment: Retail sentiment for MGNX on Stocktwits shifted from ‘bearish’ to ‘bullish’, with users expressing increased optimism about the stock's valuation, reflecting a growing confidence among investors regarding the company's future prospects.
seekingalpha
9.0
04-09seekingalpha
Macrogenics Shares Rise as FDA Lifts Clinical Hold on Lorigerlimab Trial
  • Clinical Hold Lifted: The FDA's removal of the partial clinical hold on Macrogenics' lorigerlimab mid-stage trial allows the company to begin enrolling new patients under a revised protocol, which is expected to significantly accelerate research progress and enhance market confidence.
  • Enhanced Safety Measures: The new protocol includes additional safety measures targeting potential blood and heart-related side effects, aimed at improving patient safety and reducing risks in future trials, thereby enhancing the company's reputation in the biotech sector.
  • Trial Progress Update: Macrogenics plans to provide a program update on the LINNET trial in mid-2026, indicating strong confidence in the long-term prospects of lorigerlimab, which may attract more investor interest in its future performance.
  • Positive Market Reaction: Following the FDA's lift of the partial hold, Macrogenics shares rose in premarket trading, reflecting investor optimism about the company's resumption of clinical trials, potentially driving further increases in stock price.
Wall Street analysts forecast MGNX stock price to rise
4 Analyst Rating
Wall Street analysts forecast MGNX stock price to rise
1 Buy
3 Hold
0 Sell
Hold
Current: 0.000
sliders
Low
2.00
Averages
3.00
High
4.00
Current: 0.000
sliders
Low
2.00
Averages
3.00
High
4.00
Barclays
NULL -> Overweight
maintain
$4 -> $6
AI Analysis
2026-04-20
Reason
Barclays
Price Target
$4 -> $6
AI Analysis
2026-04-20
maintain
NULL -> Overweight
Reason
Barclays raised the firm's price target on MacroGenics to $6 from $4 and keeps an Overweight rating on the shares. The firm adjusted ratings and targets in the small and mid cap biotechnology group as part of a Q1 earnings preview.
B. Riley
Neutral
to
Buy
upgrade
$9
2026-04-10
Reason
B. Riley
Price Target
$9
2026-04-10
upgrade
Neutral
to
Buy
Reason
B. Riley upgraded MacroGenics to Buy from Neutral with a $9 price target.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for MGNX
Unlock Now

Valuation Metrics

The current forward P/E ratio for MacroGenics Inc (MGNX.O) is 60.98, compared to its 5-year average forward P/E of 0.78. For a more detailed relative valuation and DCF analysis to assess MacroGenics Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
0.78
Current PE
60.98
Overvalued PE
15.38
Undervalued PE
-13.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.94
Current EV/EBITDA
-10.80
Overvalued EV/EBITDA
0.54
Undervalued EV/EBITDA
-6.42

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.94
Current PS
1.90
Overvalued PS
7.05
Undervalued PS
0.84

Financials

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Whales Holding MGNX

F
Frazier Life Sciences Management, LP
Holding
MGNX
+7.23%
3M Return

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Frequently Asked Questions

What is MacroGenics Inc (MGNX) stock price today?

The current price of MGNX is 2.95 USD — it has decreased -1.67

What is MacroGenics Inc (MGNX)'s business?

MacroGenics, Inc. is a biopharmaceutical company focused on discovering, developing, manufacturing and commercializing monoclonal antibody-based therapeutics for the treatment of cancer. The Company generates its pipeline of product candidates primarily from its suite of antibody-based technology platforms, which have applicability across broad therapeutic domains. It is advancing three proprietary product candidates in clinical development: lorigerlimab, a bispecific DART molecule that targets checkpoint inhibitors PD-1 and CTLA-4; MGC026, an ADC that targets B7-H3 and delivers a novel topoisomerase I inhibitor (TOP1i)-based linker-payload, and MGC028, an ADC that targets ADAM9 and delivers a novel TOP1i-based linker-payload. Its other product candidates are MGD024, retifanlimab, enoblituzumab, and vobramitamab duocarmazine. MGD024 is an investigational, next-generation, bispecific CD123 CD3 DART molecule designed to engage CD3 expressed on immune effector cells, such as T cells.

What is the price predicton of MGNX Stock?

Wall Street analysts forecast MGNX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for MGNX is3.00 USD with a low forecast of 2.00 USD and a high forecast of 4.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is MacroGenics Inc (MGNX)'s revenue for the last quarter?

MacroGenics Inc revenue for the last quarter amounts to 41.23M USD, increased 113.03

What is MacroGenics Inc (MGNX)'s earnings per share (EPS) for the last quarter?

MacroGenics Inc. EPS for the last quarter amounts to -0.22 USD, decreased -12.00

How many employees does MacroGenics Inc (MGNX). have?

MacroGenics Inc (MGNX) has 293 emplpoyees as of May 12 2026.

What is MacroGenics Inc (MGNX) market cap?

Today MGNX has the market capitalization of 187.50M USD.