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KZIA Overview

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Intellectia

Loading chart...

High
8.820
Open
8.060
VWAP
8.45
Vol
96.05K
Mkt Cap
96.58M
Low
8.000
Amount
811.29K
EV/EBITDA(TTM)
--
Total Shares
11.34M
EV
83.90M
EV/OCF(TTM)
--
P/S(TTM)
60.05K
Kazia Therapeutics Limited is an Australia-based pharmaceutical drug development company. The Company operates in the pharmaceutical research and development business. The Company’s lead program is paxalisib, an investigational brain-penetrant inhibitor of the PI3K / Akt / mTOR pathway, which is being developed to treat multiple forms of brain cancer. It is also developing EVT801, a small-molecule inhibitor of VEGFR3, which is critical to the development of new blood vessels and lymphatic vessels in a growing tumor, as well as to the metastasis of tumors to distant sites in the body. It designed paxalisib to inhibit PI3K, a critical control mechanism in growth and cell division, which is activated in many forms of cancer. The Company’s drug candidates are designed to treat diseases, such as brain cancer, renal cancer, and liver cancer.
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Events Timeline

(ET)
2026-01-30
08:10:00
Kazia Therapeutics Unveils NDL2 to Address Immunotherapy Resistance
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2026-01-27 (ET)
2026-01-27
08:10:00
Kazia Therapeutics Updates on TNBC Clinical Trial Progress
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2026-01-02 (ET)
2026-01-02
15:50:00
Kazia Therapeutics Trading Halted Due to Volatility
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2025-12-22 (ET)
2025-12-22
08:10:00
Kazia Therapeutics Regains Full Compliance with Nasdaq Listing Standards
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2025-12-19 (ET)
2025-12-19
16:50:00
Kazia Therapeutics Files to Sell 10.7M American Depositary Shares
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2025-12-10 (ET)
2025-12-10
08:20:00
Kazia Therapeutics Releases New Data on Paxalisib for Breast Cancer
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2025-12-02 (ET)
2025-12-02
09:50:00
Kazia Therapeutics Resumes Trading
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News

stocktwits
9.0
01-30stocktwits
Kazia's NDL2 Therapy Significantly Reduces Tumor Volume
  • Significant Tumor Volume Reduction: In murine triple-negative breast cancer preclinical models, NDL2 as a monotherapy reduced primary tumor volume by 49%, demonstrating its efficacy and potential as a standalone treatment option for future therapies.
  • Combined Therapy Effectiveness: When combined with anti-PD-1 therapy, NDL2 reduced primary tumor volume by 73%, indicating that this combination therapy has significant potential to enhance anti-tumor activity and improve patient outcomes.
  • Positive Results in Lung Metastasis Patients: In patients with lung metastases, the combination of NDL2 and anti-PD-1 therapy resulted in a 50% reduction in primary tumor volume, providing new hope for treating metastatic cancer and potentially altering clinical treatment strategies.
  • Positive Market Reaction: Kazia Therapeutics' shares rose over 6% in pre-market trading on Friday, reflecting investor optimism regarding the new data on NDL2 and indicating strong market confidence in the company's future prospects.
PRnewswire
8.5
01-30PRnewswire
Kazia Launches First-in-Class Nuclear PD-L1 Degrader NDL2
  • Novel Therapeutic Target: Kazia Therapeutics announces NDL2 as the first nuclear PD-L1 degrader, targeting a previously unaddressed mechanism of immunotherapy resistance, potentially transforming cancer treatment paradigms.
  • Significant Efficacy Data: In murine triple-negative breast cancer models, NDL2 reduced primary tumor volume by 49% as monotherapy and 73% in combination with anti-PD-1, demonstrating its robust anti-tumor activity.
  • Safety and Pharmacokinetics: NDL2 showed no toxicity in preclinical trials, preserving immune checkpoint function at the cell surface, indicating its potential safety and efficacy in clinical applications.
  • Future Development Outlook: Kazia plans to initiate first-in-human clinical trials in 2027 targeting immunotherapy-refractory solid tumors, with NDL2's development expected to create strategic partnership opportunities and long-term value.
Benzinga
9.0
01-27Benzinga
Kazia Therapeutics Provides Clinical Update on Paxalisib in TNBC Study
  • Clinical Trial Progress: Kazia Therapeutics reports significant clinical responses in its ongoing Phase 1b trial for late-stage metastatic triple-negative breast cancer, with three patients showing meaningful responses, including two partial responses and one complete metabolic response, indicating the potential of paxalisib.
  • Funding Support: In December 2025, Kazia raised approximately $46.5 million to support the continued clinical development of paxalisib, with plans to enroll twelve TNBC patients by the end of 2026, further advancing its research efforts.
  • Safety and Tolerability: Paxalisib, when combined with pembrolizumab and chemotherapy at a daily dose of 30 mg, has demonstrated a favorable safety profile, with only one case of Grade 1 hyperglycemia observed, requiring no intervention, suggesting a relatively low risk for this treatment regimen.
  • Future Plans: Kazia anticipates activating two additional clinical sites by April 2026, with plans for two more by mid-2026, aiming to accelerate patient recruitment and target topline data readout in early 2027, showcasing its strategic positioning in breast cancer treatment.
PRnewswire
9.0
01-27PRnewswire
Kazia Therapeutics Updates on Clinical Trial Progress
  • Significant Clinical Responses: In the ongoing Phase 1b trial, three patients with late-stage metastatic triple-negative breast cancer treated with paxalisib demonstrated meaningful clinical responses, including two partial responses and one confirmed complete metabolic response, indicating the potential efficacy of this therapy.
  • Trial Design and Patient Selection: This multi-center, open-label randomized study, initiated in June 2025, aims to evaluate the safety and preliminary efficacy of paxalisib in combination with standard treatment regimens, with eligibility requiring PD-L1 positive disease, ensuring scientific rigor and clinical relevance.
  • Adverse Event Monitoring: Approximately 75% of adverse events reported during treatment were assessed as unrelated to paxalisib, with most being mild to moderate, demonstrating the drug's good tolerability and laying a foundation for future clinical applications.
  • Future Development Plans: Kazia plans to activate two additional clinical trial sites by April 2026 and anticipates enrolling 12 patients by the end of 2026, further advancing paxalisib's application in broader breast cancer populations, showcasing the company's long-term commitment to this field.
Newsfilter
1.0
01-08Newsfilter
Kazia CEO John Friend to Attend JPM Week, Advancing Breast Cancer Research
  • Strategic Conference Participation: Kazia Therapeutics CEO John Friend will attend the J.P. Morgan Healthcare Conference next week in San Francisco to connect with existing and prospective investors and strategic partners, thereby enhancing the company's investor relations and business development efforts.
  • Post-Financing Momentum: Following a successful financing round, Kazia is well-capitalized to execute on multiple near-term catalysts, including an anticipated clinical and biomarker update for triple-negative breast cancer (TNBC) by the end of the month, which will enhance the company's competitiveness in oncology.
  • Clinical Update Expectations: Kazia expects to provide an update on its ongoing Phase 1b trial for TNBC by the end of January, potentially including expanded analyses of circulating tumor cells (CTCs) and CTC clusters, thereby supporting paxalisib's potential impact on metastatic disease biology with more clinical data.
  • New Drug Development Progress: Kazia plans to provide the first update on its potential first-in-class PD-L1 protein degrader program, aimed at leveraging a novel mechanism to address challenges in immune-based cancer therapies, further advancing the company's innovative capabilities in cancer treatment.
Newsfilter
3.5
01-07Newsfilter
Oncolytics Biotech Inc. Reports 33% Response Rate for Pelareorep in Colorectal Cancer
  • Market Potential: The global cancer drugs market is projected to reach $594.3 billion by 2035, with high-tech immunotherapies replacing traditional chemotherapy, positioning Oncolytics Biotech Inc. as a key player in this transformation.
  • Clinical Data Breakthrough: Oncolytics' pelareorep achieved a 33% objective response rate in second-line KRAS-mutant microsatellite-stable metastatic colorectal cancer patients when combined with standard chemotherapy, significantly surpassing the historical 6-11% response rate for chemotherapy alone, potentially driving growth in a $20 billion market.
  • Enhanced Expert Validation: Oncolytics expanded its Gastrointestinal Tumor Scientific Advisory Board with three globally recognized experts, further elevating the academic validation and industry attention for pelareorep, which may attract more investment and collaboration opportunities.
  • Successful FDA Alignment: Oncolytics has secured FDA alignment on its Phase 3 study design for pelareorep in first-line metastatic pancreatic cancer, marking the launch of the only immunotherapy registration trial planned for this disease, thereby enhancing its market competitiveness.
Wall Street analysts forecast KZIA stock price to rise
2 Analyst Rating
Wall Street analysts forecast KZIA stock price to rise
2 Buy
0 Hold
0 Sell
Moderate Buy
Current: 0.000
sliders
Low
18.00
Averages
19.00
High
20.00
Current: 0.000
sliders
Low
18.00
Averages
19.00
High
20.00
H.C. Wainwright
Buy
maintain
$13 -> $18
AI Analysis
2025-12-12
Reason
H.C. Wainwright
Price Target
$13 -> $18
AI Analysis
2025-12-12
maintain
Buy
Reason
H.C. Wainwright raised the firm's price target on Kazia Therapeutics to $18 from $13 and keeps a Buy rating on the shares. The company presented "encourating" results from its Phase 1 study of paxalisib for the treatment of triple-negative breast cancer, the analyst tells investors in a research note.
H.C. Wainwright
Sean Lee
Buy
upgrade
$2 -> $13
2025-07-10
Reason
H.C. Wainwright
Sean Lee
Price Target
$2 -> $13
2025-07-10
upgrade
Buy
Reason
H.C. Wainwright analyst Sean Lee raised the firm's price target on Kazia Therapeutics to $13 from $2 and keeps a Buy rating on the shares following the adjusted ratio of U.S. shares to 500:1 from 100:1.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for KZIA
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Valuation Metrics

The current forward P/E ratio for Kazia Therapeutics Ltd (KZIA.O) is -635.96, compared to its 5-year average forward P/E of -101.18. For a more detailed relative valuation and DCF analysis to assess Kazia Therapeutics Ltd's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-101.18
Current PE
-635.96
Overvalued PE
182.21
Undervalued PE
-384.56

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.76
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
1.51
Undervalued EV/EBITDA
-5.04

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
336.72
Current PS
1661.69
Overvalued PS
1376.98
Undervalued PS
-703.54

Financials

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Frequently Asked Questions

What is Kazia Therapeutics Ltd (KZIA) stock price today?

The current price of KZIA is 8.52 USD — it has increased 3.65

What is Kazia Therapeutics Ltd (KZIA)'s business?

Kazia Therapeutics Limited is an Australia-based pharmaceutical drug development company. The Company operates in the pharmaceutical research and development business. The Company’s lead program is paxalisib, an investigational brain-penetrant inhibitor of the PI3K / Akt / mTOR pathway, which is being developed to treat multiple forms of brain cancer. It is also developing EVT801, a small-molecule inhibitor of VEGFR3, which is critical to the development of new blood vessels and lymphatic vessels in a growing tumor, as well as to the metastasis of tumors to distant sites in the body. It designed paxalisib to inhibit PI3K, a critical control mechanism in growth and cell division, which is activated in many forms of cancer. The Company’s drug candidates are designed to treat diseases, such as brain cancer, renal cancer, and liver cancer.

What is the price predicton of KZIA Stock?

Wall Street analysts forecast KZIA stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KZIA is19.00 USD with a low forecast of 18.00 USD and a high forecast of 20.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Kazia Therapeutics Ltd (KZIA)'s revenue for the last quarter?

Kazia Therapeutics Ltd revenue for the last quarter amounts to NaN USD, decreased

What is Kazia Therapeutics Ltd (KZIA)'s earnings per share (EPS) for the last quarter?

Kazia Therapeutics Ltd. EPS for the last quarter amounts to USD, decreased

How many employees does Kazia Therapeutics Ltd (KZIA). have?

Kazia Therapeutics Ltd (KZIA) has 9 emplpoyees as of March 11 2026.

What is Kazia Therapeutics Ltd (KZIA) market cap?

Today KZIA has the market capitalization of 96.58M USD.