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KRYS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
258.630
Open
257.640
VWAP
255.98
Vol
163.41K
Mkt Cap
7.45B
Low
254.310
Amount
41.83M
EV/EBITDA(TTM)
40.78
Total Shares
29.23M
EV
6.80B
EV/OCF(TTM)
33.87
P/S(TTM)
20.09
Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications.
Show More

Events Timeline

(ET)
2026-02-17
07:10:00
Krystal Biotech Q4 Revenue $107.1M Beats Expectations
select
2026-02-17
07:10:00
Krystal Biotech Sees FY26 Non-GAAP R&D, SG&A Expense $175M-$195M
select
2026-02-09 (ET)
2026-02-09
08:10:00
Krystal Biotech's KB707 Receives FDA Regenerative Medicine Advanced Therapy Designation
select

News

moomoo
5.0
02-27moomoo
Krystal Biotech (KRYS.US) Director Plans to Sell $3.25 Million in Common Stock via Form 144
  • Stock Sale Announcement: Daniel S. Janney, director of Krystal Biotech (KRYS.US), plans to sell 11,803 shares of the company's common stock on February 27, with an estimated market value of around $3.25 million.

  • Reduction in Shareholding: Since February 24, 2026, Janney has reduced his shareholding in Krystal Biotech by 60,161 shares, valued at approximately $16.15 million.

Fool
8.5
02-22Fool
Redmile Group Increases Stake in Krystal Biotech
  • Share Acquisition: Redmile Group reported an acquisition of 16,317 shares of Krystal Biotech in its SEC filing dated February 17, 2026, with an estimated transaction value of $3.43 million, indicating strong confidence in the company.
  • Increased Ownership: Following this purchase, Krystal Biotech now represents 12.3% of Redmile's 13F-reportable AUM, highlighting its significance within the investment portfolio.
  • Strong Financial Performance: Krystal Biotech achieved $107.1 million in VYJUVEK revenue for Q4 2025, contributing to total product sales of $389.1 million for the year, with a gross margin of 94%, demonstrating the sustainability of its business model.
  • Outstanding Market Performance: The stock price of Krystal Biotech has risen 44% over the past year, significantly outperforming the S&P 500's 13% gain, reflecting market recognition of its future growth potential.
Yahoo Finance
8.5
02-22Yahoo Finance
Redmile Group Increases Stake in Scholar Rock Holding Corporation by $49 Million
  • Share Acquisition: Redmile Group disclosed in an SEC filing on February 17, 2026, that it purchased 1,316,390 shares of Scholar Rock Holding Corporation, with an estimated transaction value of $49.37 million, indicating strong confidence in the company.
  • Increased Ownership: Following this acquisition, Redmile Group's stake in Scholar Rock rises to 16.94%, representing 16.9% of the fund's 13F reportable assets, further solidifying its investment position in the biopharmaceutical sector.
  • Strong Market Performance: As of February 17, 2026, Scholar Rock's share price stood at $46.45, reflecting a 25.7% increase over the past year, outperforming the S&P 500 by 13.39 percentage points, showcasing market recognition of its growth potential.
  • Robust Financial Position: Scholar Rock reported approximately $365 million in cash as of December 31, 2026, projected to sustain operations into 2027, thereby reducing near-term dilution risk and providing confidence for long-term investors.
Yahoo Finance
4.5
02-18Yahoo Finance
Stock Market Rebounds Slightly, Nvidia Gains from Meta AI Deal
  • Market Rebound: The stock market experienced a slight rebound on Tuesday, despite remaining divided, indicating cautious optimism among investors that could provide some support for future trading.
  • Nvidia Gains: Nvidia's stock rose late in the session due to a deal with Meta in the AI sector, reflecting ongoing market confidence in its capabilities, which may drive future earnings growth.
  • AMD and Broadcom Decline: In contrast, AMD and Broadcom saw their stock prices slump, suggesting a cautious outlook from the market regarding these companies, which could affect their short-term investment appeal.
  • Increased Industry Divergence: The overall market divergence has intensified, with some tech stocks performing well while others face pressure, potentially leading investors to be more selective in their stock choices, impacting overall market liquidity.
Yahoo Finance
2.0
02-18Yahoo Finance
Stock Market Rebounds Slightly, Nvidia Gains from Meta AI Deal
  • Market Rebound: The stock market experienced a slight rebound on Tuesday, despite remaining divided, indicating cautious optimism among investors that may provide some support for future trading.
  • Nvidia Gains: Nvidia's stock rose late in the session due to a deal with Meta in the AI sector, highlighting its ongoing leadership in AI and potential new growth opportunities for the company.
  • AMD and Broadcom Decline: In contrast, AMD and Broadcom saw their stock prices slump, reflecting market concerns about the semiconductor industry, which could impact investor confidence and future investment decisions in this sector.
  • Divergent Investor Sentiment: While Nvidia performed strongly, the overall market sentiment remains divided, prompting investors to closely monitor industry dynamics and company fundamentals to make more informed investment choices.
seekingalpha
9.5
02-17seekingalpha
Krystal Biotech Q4 2025 Earnings Call Highlights
  • Significant Sales Growth: Krystal Biotech reported net revenue of $107.1 million for Q4 2025, marking nearly a 10% increase from the previous quarter and an 18% rise year-over-year, indicating strong market demand and enhanced sales capacity.
  • International Expansion Plans: The company signed distributor agreements covering over 20 countries and aims to expand to more than 40 countries in 2026, reflecting its proactive global market strategy and commitment to international growth.
  • High Gross Margin Maintenance: The gross margin for Q4 was 94%, with expectations to remain in the 90% to 95% range moving forward, demonstrating the company's strong performance in cost control and profitability despite rising costs.
  • Investment in R&D and Marketing: The guidance for 2026 non-GAAP operating expenses is set at approximately $175 million to $195 million, reflecting ongoing investments in global launches and pipeline development, aimed at supporting future growth and innovation.
Wall Street analysts forecast KRYS stock price to rise
9 Analyst Rating
Wall Street analysts forecast KRYS stock price to rise
8 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
198.00
Averages
229.25
High
278.00
Current: 0.000
sliders
Low
198.00
Averages
229.25
High
278.00
Guggenheim
Buy
maintain
$224 -> $284
AI Analysis
2026-02-25
Reason
Guggenheim
Price Target
$224 -> $284
AI Analysis
2026-02-25
maintain
Buy
Reason
Guggenheim raised the firm's price target on Krystal Biotech to $284 from $224 and keeps a Buy rating on the shares. The firm updated its model following the company's Q4 report.
Chardan
Geulah Livshits
Buy
maintain
$220 -> $323
2026-02-18
Reason
Chardan
Geulah Livshits
Price Target
$220 -> $323
2026-02-18
maintain
Buy
Reason
Chardan analyst Geulah Livshits raised the firm's price target on Krystal Biotech to $323 from $220 and keeps a Buy rating on the shares. The firm is updating its model for FY25 financials, the Vyjuvek launch trajectory, and registrational trial progress for four programs, the analyst tells investors in a post-earnings note.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for KRYS
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Valuation Metrics

The current forward P/E ratio for Krystal Biotech Inc (KRYS.O) is 34.94, compared to its 5-year average forward P/E of -13.94. For a more detailed relative valuation and DCF analysis to assess Krystal Biotech Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-13.94
Current PE
34.94
Overvalued PE
54.44
Undervalued PE
-82.32

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
14.43
Current EV/EBITDA
26.65
Overvalued EV/EBITDA
61.20
Undervalued EV/EBITDA
-32.35

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
171.15
Current PS
13.92
Overvalued PS
760.80
Undervalued PS
-418.49

Financials

AI Analysis
Annual
Quarterly

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Whales Holding KRYS

H
Hood River Capital Management LLC
Holding
KRYS
+18.06%
3M Return
F
Frazier Life Sciences Management, LP
Holding
KRYS
+8.24%
3M Return
B
Braidwell LP
Holding
KRYS
+0.39%
3M Return
B
Bellevue Asset Management AG
Holding
KRYS
-3.05%
3M Return
A
Avoro Capital Advisors LLC
Holding
KRYS
-4.45%
3M Return
S
Soleus Capital Management, L.P.
Holding
KRYS
-5.11%
3M Return

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Frequently Asked Questions

What is Krystal Biotech Inc (KRYS) stock price today?

The current price of KRYS is 255 USD — it has decreased -2.33

What is Krystal Biotech Inc (KRYS)'s business?

Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications.

What is the price predicton of KRYS Stock?

Wall Street analysts forecast KRYS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KRYS is229.25 USD with a low forecast of 198.00 USD and a high forecast of 278.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Krystal Biotech Inc (KRYS)'s revenue for the last quarter?

Krystal Biotech Inc revenue for the last quarter amounts to 107.11M USD, increased 17.52

What is Krystal Biotech Inc (KRYS)'s earnings per share (EPS) for the last quarter?

Krystal Biotech Inc. EPS for the last quarter amounts to 1.70 USD, increased 11.84

How many employees does Krystal Biotech Inc (KRYS). have?

Krystal Biotech Inc (KRYS) has 295 emplpoyees as of March 12 2026.

What is Krystal Biotech Inc (KRYS) market cap?

Today KRYS has the market capitalization of 7.45B USD.