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KRYS Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
310.000
Open
308.480
VWAP
308.96
Vol
18.45K
Mkt Cap
9.01B
Low
308.380
Amount
5.70M
EV/EBITDA(TTM)
44.39
Total Shares
29.48M
EV
8.19B
EV/OCF(TTM)
32.72
P/S(TTM)
22.05
Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications.
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Events Timeline

(ET)
2026-05-04
07:10:00
Krystal Biotech Sees FY26 R&D and SG&A Expense of $175M-$195M
select
2026-05-04
07:10:00
Krystal Biotech Q1 Revenue $116.36M Beats Expectations
select

News

Yahoo Finance
8.5
05-10Yahoo Finance
ACT Capital Management Acquires New Position in Alumis Worth $4.36 Million
  • New Position: On May 8, 2026, ACT Capital Management disclosed a new position in Alumis by acquiring 174,250 shares valued at approximately $4.36 million, indicating strong confidence in the company's future prospects.
  • Quarterly Valuation: The position's valuation stood at $3.84 million at quarter-end, reflecting the impact of market price changes and share count, highlighting Alumis's significance in the investment portfolio.
  • Stock Performance: Alumis shares surged 350% over the past year, significantly outperforming the S&P 500's 30% gain, showcasing its robust growth potential in the biopharmaceutical sector.
  • Clinical Progress: Alumis reported positive Phase 3 data for moderate-to-severe plaque psoriasis in March, with plans to submit a New Drug Application in the second half of 2026, further boosting investor confidence in its drug development pipeline.
seekingalpha
9.5
05-04seekingalpha
Krystal Biotech Reports Q1 2026 Earnings with Strong Revenue Growth
  • Global Revenue Growth: Krystal Biotech reported net revenue of $116.4 million in Q1 2026, showcasing strong performance in global markets, particularly in VYJUVEK sales, which is expected to drive future growth.
  • High Gross Margin: The company achieved a gross margin of 95% and delivered its 11th consecutive quarter of positive EPS, which not only boosts investor confidence but also provides a solid foundation for future capital operations.
  • International Market Contribution: The European and Japanese markets contributed $28.9 million in net revenue, indicating the significant role these regions play in VYJUVEK's growth potential, with prospects for further market share expansion.
  • R&D and Expense Outlook: The company anticipates non-GAAP R&D and SG&A expenses between $175 million and $195 million for 2026, and with over $1 billion in cash and investments, it indicates strong financial support for future R&D and market expansion.
seekingalpha
9.5
05-04seekingalpha
Krystal Biotech Q1 Earnings Exceed Expectations
  • Strong Earnings Performance: Krystal Biotech reported a Q1 GAAP EPS of $1.83, beating expectations by $0.39, which reflects the company's robust profitability and enhances investor confidence in its financial health.
  • Significant Revenue Growth: The company achieved Q1 revenue of $116.36 million, representing a 32.0% year-over-year increase and exceeding market expectations by $4.23 million, indicating sustained strong demand for its products and driving overall performance.
  • Optimistic Financial Guidance: Krystal Biotech projects its FY 2026 non-GAAP R&D and SG&A expenses to be between $175 million and $195 million, reflecting confidence in future investments and strategic planning for continued growth.
  • Global Expansion Plans: The company aims to launch VYJUVEK in Italy in H2 2026, targeting global market expansion while maintaining a gross margin outlook of 90%-95%, demonstrating its ambition and sustainable profitability in international markets.
seekingalpha
9.5
05-01seekingalpha
Krystal Biotech to Announce Q1 Earnings on May 4th
  • Earnings Announcement: Krystal Biotech (KRYS) is set to announce its Q1 2023 earnings on May 4th before market open, with a consensus EPS estimate of $1.42, reflecting an 18.3% year-over-year increase, indicating ongoing improvements in profitability.
  • Revenue Expectations: The anticipated revenue for Q1 is $112.13 million, representing a 27.2% year-over-year growth, which underscores strong market demand and sales performance, potentially boosting investor confidence.
  • Historical Performance: Over the past two years, Krystal Biotech has only beaten EPS estimates 25% of the time and revenue estimates 50% of the time, indicating performance volatility that investors should monitor for future stability.
  • Estimate Revisions: In the last three months, there have been no upward revisions to EPS estimates and one downward revision, while revenue estimates saw one upward and two downward revisions, suggesting a cautious market outlook on the company's future performance.
NASDAQ.COM
5.0
04-16NASDAQ.COM
Three Biotech Companies Worth Watching
  • Krystal Biotech's Breakthrough: In 2023, Krystal Biotech received approval for Vyjuvek, a gene therapy for Dystrophic Epidermolysis Bullosa, achieving $389.1 million in revenue, a 34% year-over-year increase, indicating strong market potential in rare diseases.
  • Madrigal Pharmaceuticals' FDA Approval: In 2024, Madrigal gained FDA approval for Rezdiffra, the first drug for metabolic dysfunction-associated steatohepatitis, with 2025 revenue reaching $958.4 million, a staggering 432% increase, showcasing robust growth in an emerging market.
  • Exelixis' Oncology Innovations: Exelixis' Cabometyx remains the leading treatment for liver and kidney cancers, with no generic competition expected until 2030, while the company plans to launch several next-gen cancer therapies in the next five years, further solidifying its market position.
  • Significant Market Potential: The combination of innovation and market demand in these three companies suggests that their stocks could yield substantial returns in the future, particularly in the ongoing developments within rare diseases and oncology.
Fool
2.0
04-16Fool
Three Biotech Stocks Worth Watching
  • Krystal Biotech's Breakthrough: Focused on rare diseases, Krystal Biotech received approval for Vyjuvek, a gene therapy for Dystrophic Epidermolysis Bullosa, achieving $389.1 million in revenue in 2023, a 34% year-over-year increase, indicating strong market performance.
  • Madrigal Pharmaceuticals' Market Potential: Madrigal's Rezdiffra, approved by the FDA in 2024 as the first treatment for metabolic dysfunction-associated steatohepatitis, generated $958.4 million in revenue in 2025, a staggering 432% increase, showcasing its potential in a large patient market.
  • Exelixis' Innovative Drugs: Exelixis' Cabometyx, a leading treatment for liver and kidney cancers, is expected to face no generic competition until 2030, while its development of next-gen cancer therapies could further drive growth in the coming years.
  • Competitive Advantages: These three companies demonstrate significant market potential and innovation capabilities, with Krystal Biotech and Madrigal expanding their product lines to enhance market share, while Exelixis maintains a strong position in oncology through robust financial performance and R&D efforts.
Wall Street analysts forecast KRYS stock price to rise
9 Analyst Rating
Wall Street analysts forecast KRYS stock price to rise
8 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
198.00
Averages
229.25
High
278.00
Current: 0.000
sliders
Low
198.00
Averages
229.25
High
278.00
Evercore ISI
NULL
to
Outperform
maintain
$295 -> $300
AI Analysis
2026-05-05
Reason
Evercore ISI
Price Target
$295 -> $300
AI Analysis
2026-05-05
maintain
NULL
to
Outperform
Reason
Evercore ISI raised the firm's price target on Krystal Biotech to $300 from $295 and keeps an Outperform rating on the shares.
Citi
Buy
maintain
$371 -> $378
2026-05-05
Reason
Citi
Price Target
$371 -> $378
2026-05-05
maintain
Buy
Reason
Citi raised the firm's price target on Krystal Biotech to $378 from $371 and keeps a Buy rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for KRYS
Unlock Now

Valuation Metrics

The current forward P/E ratio for Krystal Biotech Inc (KRYS.O) is 49.75, compared to its 5-year average forward P/E of -9.48. For a more detailed relative valuation and DCF analysis to assess Krystal Biotech Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-9.48
Current PE
49.75
Overvalued PE
59.32
Undervalued PE
-78.29

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
16.39
Current EV/EBITDA
25.85
Overvalued EV/EBITDA
61.84
Undervalued EV/EBITDA
-29.05

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
165.50
Current PS
12.91
Overvalued PS
745.13
Undervalued PS
-414.13

Financials

AI Analysis
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Whales Holding KRYS

H
Hood River Capital Management LLC
Holding
KRYS
+19.19%
3M Return
B
Braidwell LP
Holding
KRYS
+17.70%
3M Return
A
Avoro Capital Advisors LLC
Holding
KRYS
+14.33%
3M Return
S
Soleus Capital Management, L.P.
Holding
KRYS
+8.19%
3M Return
F
Frazier Life Sciences Management, LP
Holding
KRYS
+5.82%
3M Return
B
Bellevue Asset Management AG
Holding
KRYS
-1.65%
3M Return

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Frequently Asked Questions

What is Krystal Biotech Inc (KRYS) stock price today?

The current price of KRYS is 308.5 USD — it has increased 0.91

What is Krystal Biotech Inc (KRYS)'s business?

Krystal Biotech, Inc. is an integrated, commercial-stage biotechnology company. The Company is focused on the discovery, development, and commercialization of genetic medicines to treat diseases with high unmet medical needs. Its product candidates in various stages of clinical and preclinical development include KB407, KB408, KB707, KB105, KB801, KB803, KB304 and KB301. Its commercial product, VYJUVEK, is a redosable gene therapy, and a genetic medicine approved in the United States and Europe for the treatment of dystrophic epidermolysis bullosa. KB407 is being developed for the treatment of Cystic Fibrosis. KB408 is being developed for the treatment of Alpha-1 Antitrypsin Deficiency, a rare lung disease. KB707 is being developed for the treatment of solid tumors. KB105 is being developed for TGM1-Deficient Autosomal Recessive Congenital Ichthyosis. KB803 is a redosable eye drop formulation of B-VEC, designed for the treatment of ocular complications.

What is the price predicton of KRYS Stock?

Wall Street analysts forecast KRYS stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for KRYS is229.25 USD with a low forecast of 198.00 USD and a high forecast of 278.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Krystal Biotech Inc (KRYS)'s revenue for the last quarter?

Krystal Biotech Inc revenue for the last quarter amounts to 116.36M USD, increased 31.95

What is Krystal Biotech Inc (KRYS)'s earnings per share (EPS) for the last quarter?

Krystal Biotech Inc. EPS for the last quarter amounts to 1.83 USD, increased 52.50

How many employees does Krystal Biotech Inc (KRYS). have?

Krystal Biotech Inc (KRYS) has 295 emplpoyees as of May 11 2026.

What is Krystal Biotech Inc (KRYS) market cap?

Today KRYS has the market capitalization of 9.01B USD.