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PRAX Overview

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0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
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ET
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Intellectia

Loading chart...

High
346.345
Open
326.260
VWAP
337.91
Vol
425.29K
Mkt Cap
9.54B
Low
324.870
Amount
143.71M
EV/EBITDA(TTM)
--
Total Shares
27.85M
EV
8.94B
EV/OCF(TTM)
--
P/S(TTM)
--
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.
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Events Timeline

(ET)
2026-04-14
07:40:00
Praxis Precision's NDA for Ulixacaltamide HCl Accepted by FDA
select
2026-04-06 (ET)
2026-04-06
08:10:00
Praxis Precision Announces EMBRAVE Trial Results for Elsunersen
select
2026-03-30 (ET)
2026-03-30
16:20:00
Praxis Precision's New Drug Application for Relutrigine Accepted for Priority Review by FDA
select

News

seekingalpha
8.5
04-14seekingalpha
Praxis Precision Medicines FDA Accepts New Drug Application for Ulixacaltamide
  • FDA Application Progress: Praxis Precision Medicines' new drug application for ulixacaltamide HCl has been accepted for review by the FDA, marking a significant advancement in addressing essential tremor, a common movement disorder affecting nearly 7 million Americans, which is expected to enhance the company's market competitiveness.
  • Clinical Trial Success: The application is supported by data from the company's Essential3 Phase 3 clinical trials, where two pivotal studies met their primary endpoints, demonstrating statistically and clinically significant results for ulixacaltamide in adults with essential tremor, further strengthening its market outlook.
  • Target Action Date: The FDA has set January 29, 2027, as the target action date for the new drug application and has not indicated plans for an advisory committee meeting, which could expedite the approval process and boost investor confidence.
  • Positive Market Reaction: Praxis's stock rose approximately 6% in premarket trading, reflecting investor optimism regarding the FDA's acceptance of the application, signaling potential future growth for the company.
NASDAQ.COM
9.0
04-14NASDAQ.COM
Praxis Precision Medicines' NDA for Ulixacaltamide Accepted by FDA
  • FDA Review Acceptance: Praxis Precision Medicines announced that its New Drug Application (NDA) for ulixacaltamide HCl for treating essential tremor in adults has been accepted for review by the FDA, marking a significant advancement in the company's therapeutic pipeline.
  • Key Timeline: The FDA has set a target action date of January 29, 2027, under the Prescription Drug User Fee Act (PDUFA), indicating that the company will face a critical regulatory review phase in its development plans over the coming years.
  • Clinical Trial Support: The NDA submission is backed by positive results from the Essential3 Phase 3 clinical program, which included two concurrently enrolled pivotal studies demonstrating statistically and clinically significant efficacy, laying a solid foundation for the drug's market potential.
  • Good Safety Profile: Ulixacaltamide was generally well tolerated in clinical trials, with a safety profile consistent with previous studies and no drug-related serious adverse events reported, enhancing the likelihood of FDA approval.
Newsfilter
9.0
04-14Newsfilter
Praxis Receives FDA Review Acceptance for Ulixacaltamide NDA
  • FDA Review Progress: Praxis Precision Medicines announced that its New Drug Application for ulixacaltamide HCl for treating essential tremor in adults has been accepted for review by the FDA, with a target action date set for January 29, 2027, marking a significant milestone in the company's CNS drug development.
  • Clinical Trial Support: The NDA is supported by positive results from the Essential3 Phase 3 clinical trials, which demonstrated statistically and clinically significant efficacy of ulixacaltamide in treating essential tremor, further enhancing its market potential.
  • Good Safety Profile: Ulixacaltamide exhibited good tolerability in clinical trials, with a safety profile consistent with previous studies and no drug-related serious adverse events, laying a solid foundation for its future commercialization.
  • Breakthrough Therapy Designation: The drug received Breakthrough Therapy Designation from the FDA in December 2025, highlighting its innovation and market demand in treating essential tremor, as Praxis continues to collaborate with the FDA in preparation for its commercial launch.
moomoo
4.0
04-10moomoo
PRAXIS PRECISION MEDICINES INC: RAYMOND JAMES BEGINS COVERAGE WITH A STRONG BUY RATING AND A TARGET PRICE OF $815
  • Company Overview: Praxis Precision Medicines is highlighted for its strong buy rating, indicating positive investor sentiment and confidence in the company's future performance.

  • Target Price: The target price for Praxis Precision Medicines is set at $815, suggesting significant potential for growth based on current market evaluations.

seekingalpha
9.5
04-06seekingalpha
Praxis Precision Medicines Reports Promising Drug Results
  • Clinical Trial Results: Praxis Precision Medicines reported a 77% placebo-adjusted seizure reduction for elsunersen in the EMBRAVE Part A trial, indicating significant efficacy in treating early-onset SCN2A developmental and epileptic encephalopathy.
  • Positive Patient Response: 57% of patients remained seizure-free for at least 28 days post-treatment, and results were sustained for up to one year in the open-label extension, demonstrating the drug's long-term efficacy and safety.
  • Good Safety Profile: No severe drug-related adverse events were reported during the trial, with most treatment-emergent adverse events being mild to moderate, indicating a high safety profile for the drug.
  • Positive Market Reaction: Following the promising trial results, Praxis Precision Medicines saw its stock rise approximately 5% in premarket trading, reflecting investor optimism about the company's future prospects.
Newsfilter
9.0
03-30Newsfilter
Praxis Receives FDA Priority Review for Relutrigine
  • FDA Review Progress: Praxis Precision Medicines announced that its New Drug Application (NDA) has been accepted for priority review by the FDA, with a target action date of September 27, 2026, marking a significant milestone in the company's evolution towards commercialization, as approval would make it the first disease-modifying therapy for SCN2A and SCN8A developmental epileptic encephalopathies.
  • Clinical Trial Results: The NDA is supported by positive results from the EMBOLD study, which was stopped early for efficacy, demonstrating significant therapeutic effects of relutrigine in patients with severe epilepsy, potentially improving their quality of life.
  • Drug Designations: Relutrigine has received Orphan Drug, Rare Pediatric Disease, and Breakthrough Therapy designations from the FDA, and if approved, it will be eligible for a Pediatric Review Voucher, enhancing its competitive position in the market.
  • Future Research Plans: The drug is also being investigated in the EMERALD trial for broader DEEs, expected to be completed by the end of 2026, showcasing Praxis's ongoing innovation and commitment in the epilepsy treatment space.
Wall Street analysts forecast PRAX stock price to rise
15 Analyst Rating
Wall Street analysts forecast PRAX stock price to rise
14 Buy
0 Hold
1 Sell
Strong Buy
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Deutsche Bank
Buy
maintain
$412 -> $437
AI Analysis
2026-04-15
New
Reason
Deutsche Bank
Price Target
$412 -> $437
AI Analysis
2026-04-15
New
maintain
Buy
Reason
Deutsche Bank raised the firm's price target on Praxis Precision to $437 from $412 and keeps a Buy rating on the shares.
Raymond James
Strong Buy
initiated
$815
2026-04-10
Reason
Raymond James
Price Target
$815
2026-04-10
initiated
Strong Buy
Reason
Raymond James last night initiated coverage of Praxis Precision with a Strong Buy rating and $815 price target. The firm says the bear thesis on the name "is a conclusion in search of facts." Ulixacaltamide's potential FDA approval in early 2027 is the key catalyst for the stock over the next 12 months, the analyst tells investors in a research note. penalty. At Praxis' current valuation, Raymond James believes investors are "materially underpricing" ulixacaltamide's probability of approval.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PRAX
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Valuation Metrics

The current forward P/E ratio for Praxis Precision Medicines Inc (PRAX.O) is 0.00, compared to its 5-year average forward P/E of -4.07. For a more detailed relative valuation and DCF analysis to assess Praxis Precision Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.07
Current PE
0.00
Overvalued PE
-0.57
Undervalued PE
-7.57

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.51
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.87
Undervalued EV/EBITDA
-5.89

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
667.64
Current PS
29.55
Overvalued PS
2069.11
Undervalued PS
-733.83

Financials

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Whales Holding PRAX

J
Janus Henderson Group plc
Holding
PRAX
+47.97%
3M Return
V
Vivo Capital, LLC
Holding
PRAX
+19.07%
3M Return
A
Algert Global LLC
Holding
PRAX
+16.26%
3M Return
H
Hood River Capital Management LLC
Holding
PRAX
+16.06%
3M Return
P
Perceptive Advisors LLC
Holding
PRAX
+15.99%
3M Return
A
Allan Gray Australia Pty Ltd.
Holding
PRAX
+11.18%
3M Return

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Frequently Asked Questions

What is Praxis Precision Medicines Inc (PRAX) stock price today?

The current price of PRAX is 342.5 USD — it has increased 6.9

What is Praxis Precision Medicines Inc (PRAX)'s business?

Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.

What is the price predicton of PRAX Stock?

Wall Street analysts forecast PRAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRAX is456.71 USD with a low forecast of 95.00 USD and a high forecast of 843.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Praxis Precision Medicines Inc (PRAX)'s revenue for the last quarter?

Praxis Precision Medicines Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Praxis Precision Medicines Inc (PRAX)'s earnings per share (EPS) for the last quarter?

Praxis Precision Medicines Inc. EPS for the last quarter amounts to -3.49 USD, increased 19.11

How many employees does Praxis Precision Medicines Inc (PRAX). have?

Praxis Precision Medicines Inc (PRAX) has 168 emplpoyees as of April 20 2026.

What is Praxis Precision Medicines Inc (PRAX) market cap?

Today PRAX has the market capitalization of 9.54B USD.