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PRAX Overview

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ET
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0.000(0.000%)
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ET
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Intellectia

Loading chart...

High
323.870
Open
305.790
VWAP
313.09
Vol
417.28K
Mkt Cap
8.63B
Low
305.490
Amount
130.65M
EV/EBITDA(TTM)
--
Total Shares
27.85M
EV
8.01B
EV/OCF(TTM)
--
P/S(TTM)
--
Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.
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Events Timeline

(ET)
2026-02-19
07:40:00
Company Reports Q4 Revenue of $0, 2026 Revenue Potential Over $20B
select
2026-02-19
07:40:00
Praxis Cash and Securities Increase to $926.1 Million
select

News

Benzinga
8.5
03-09Benzinga
Xenon Pharmaceuticals Reports Positive Phase 3 X-TOLE2 Study Results
  • Positive Study Results: Xenon Pharmaceuticals announced positive topline results from the Phase 3 X-TOLE2 study of azetukalner in focal onset seizures, with a placebo-adjusted median percentage change of -42.7% in the 25 mg group, significantly outperforming the previous Phase 2b study results.
  • Primary Endpoint Achieved: The study met its primary endpoint, with 54.8% of participants in the 25 mg group achieving at least a 50% reduction in monthly seizure frequency compared to 20.8% in the placebo group, demonstrating the efficacy of azetukalner.
  • Future Application Plans: Xenon plans to submit a New Drug Application (NDA) to the FDA in Q3 2026, and if approved, azetukalner will be the only KV7 potassium channel opener available for epilepsy treatment, potentially transforming the treatment landscape for patients with uncontrolled seizures.
  • Positive Market Reaction: Xenon shares rose 16.17% to $48.72 in premarket trading on Monday, reflecting strong investor response to the study results, while analysts maintain a Buy rating with an average price target of $56.78.
Yahoo Finance
5.0
03-04Yahoo Finance
Praxis Grants Restricted Stock Units to New Employees
  • Employee Incentive Program: On March 2, 2026, Praxis Precision Medicines granted 2,931 restricted stock units to fourteen new non-executive employees, aimed at attracting top talent in compliance with Nasdaq Listing Rule 5635(c)(4).
  • Stock Unit Vesting Schedule: The restricted stock units will vest in four equal annual installments, contingent upon the employees' continued employment, thereby aligning employee interests with the company's long-term goals and enhancing retention rates.
  • Strategic Talent Acquisition: This grant is part of the 2024 Inducement Plan, specifically designed to attract individuals who were not previously employed by the company, highlighting Praxis's commitment to talent acquisition and its competitive edge in the biopharmaceutical industry.
  • Company Overview: Praxis is a leading CNS precision neuroscience biopharmaceutical company focused on translating insights from genetic epilepsies into therapies for CNS disorders, boasting multiple late-stage product candidates that demonstrate strong R&D capabilities and market potential.
Fool
6.5
02-23Fool
Baker Bros. Increases Praxis Stake to 1.94% with $81.38M Purchase
  • Stake Increase: Baker Bros. Advisors increased its stake in Praxis Precision Medicines by 437,000 shares during Q4 2025, valued at $81.38 million, indicating strong confidence in the company's future prospects.
  • Market Valuation Growth: The post-trade valuation of Praxis increased by $295.48 million due to trading activity and price movements, reflecting positive market sentiment towards its clinical-stage therapies.
  • R&D Investment: In 2025, Praxis reported R&D expenses of $267.1 million, with a net loss of $303.3 million, yet the company remains committed to advancing its treatments for central nervous system disorders.
  • Cash Flow Position: As of the end of 2025, Praxis had $926.1 million in cash and investments, with an additional $621 million from a January 2026 offering expected to fund operations into 2028, demonstrating financial stability.
NASDAQ.COM
6.5
02-23NASDAQ.COM
Baker Bros. Advisors Increases Stake in Praxis Precision Medicines
  • Share Acquisition: Baker Bros. Advisors LP increased its stake in Praxis Precision Medicines by 437,000 shares in Q4 2025, with an estimated transaction value of $81.38 million, indicating strong confidence in the company's future prospects.
  • Market Value Increase: Following the acquisition, Baker Bros. now holds 1,126,488 shares, with the quarter-end position value rising by $295.48 million, reflecting both stock price appreciation and active trading dynamics.
  • Strong Financial Position: Praxis Precision Medicines ended 2025 with $926.1 million in cash and investments, and an additional $621 million from a January 2026 offering is expected to fund operations through 2028, showcasing a robust financial foundation.
  • R&D Investment: The company reported $267.1 million in R&D expenses for 2025, with a full-year net loss of $303.3 million; however, its strategic focus on CNS therapeutics continues to attract investor interest due to significant revenue potential.
Fool
6.5
02-22Fool
Perceptive Advisors Increases Stake in Praxis Precision Medicines
  • Stake Increase: Perceptive Advisors increased its stake in Praxis Precision Medicines by 431,432 shares during Q4 2025, with an estimated transaction value of $80.34 million, reflecting strong confidence in the company's future prospects.
  • Market Value Growth: Following this purchase, Praxis's quarter-end market value increased by $505.38 million, indicating a dual impact from both the share purchase and subsequent stock price appreciation, showcasing market recognition of its clinical pipeline.
  • Financial Position: As of February 17, 2026, Praxis shares were priced at $328.04, up 320% year-over-year, while the company reported $926 million in cash and investments, providing ample financial support for future commercialization efforts.
  • R&D Investment: In 2025, Praxis's research and development spending reached $267 million, indicating a significant investment in multiple programs aimed at accelerating the development of its clinical-stage drug candidates.
Yahoo Finance
6.5
02-22Yahoo Finance
Perceptive Advisors Acquires 431,432 Shares of Praxis Precision Medicines
  • Share Acquisition Details: Perceptive Advisors increased its stake in Praxis Precision Medicines by 431,432 shares during Q4 2025, with an estimated transaction value of $80.34 million, reflecting strong confidence in the company's future prospects.
  • Position Value Growth: Following this acquisition, the value of Praxis's holdings reached $588.30 million, an increase of $505.38 million from the previous quarter-end, indicating significant stock price appreciation and positive investor sentiment.
  • Financial Overview: As of February 17, 2026, Praxis shares were priced at $328.04, up 320% year-over-year, despite a net loss of $273.04 million in 2025, suggesting market optimism regarding its future product pipeline.
  • R&D and Market Outlook: Praxis has submitted two NDAs to the FDA and is actively preparing for commercialization, with multiple clinical trial results expected in 2026, which could further enhance its market position in the central nervous system sector.
Wall Street analysts forecast PRAX stock price to rise
15 Analyst Rating
Wall Street analysts forecast PRAX stock price to rise
14 Buy
0 Hold
1 Sell
Strong Buy
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Wolfe Research
Outperform
initiated
$500
AI Analysis
2026-02-23
Reason
Wolfe Research
Price Target
$500
AI Analysis
2026-02-23
initiated
Outperform
Reason
Wolfe Research initiated coverage of Praxis Precision with an Outperform rating and $500 price target. The firm launched coverage of the neuroscience biotech sector with a "portfolio of high conviction names across multiple therapeutic areas." Wolfe believes Praxis could become a key player in neurology for both essential tremor and epilepsy.
Baird
NULL -> Outperform
upgrade
$275 -> $433
2026-02-20
Reason
Baird
Price Target
$275 -> $433
2026-02-20
upgrade
NULL -> Outperform
Reason
Baird raised the firm's price target on Praxis Precision to $433 from $275 and keeps an Outperform rating on the shares. The firm raised its target as two NDA submissions kick off the FDA review process.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PRAX
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Valuation Metrics

The current forward P/E ratio for Praxis Precision Medicines Inc (PRAX.O) is -21.34, compared to its 5-year average forward P/E of -4.22. For a more detailed relative valuation and DCF analysis to assess Praxis Precision Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.22
Current PE
-21.34
Overvalued PE
-0.62
Undervalued PE
-7.82

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.65
Current EV/EBITDA
-20.94
Overvalued EV/EBITDA
0.84
Undervalued EV/EBITDA
-6.14

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
697.72
Current PS
8230.35
Overvalued PS
2136.33
Undervalued PS
-740.88

Financials

AI Analysis
Annual
Quarterly

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Whales Holding PRAX

A
Allan Gray Australia Pty Ltd.
Holding
PRAX
+19.40%
3M Return
A
Algert Global LLC
Holding
PRAX
+15.40%
3M Return
H
Hood River Capital Management LLC
Holding
PRAX
+11.67%
3M Return
D
Driehaus Capital Management LLC
Holding
PRAX
+8.18%
3M Return
V
Vivo Capital, LLC
Holding
PRAX
+6.91%
3M Return
P
Perceptive Advisors LLC
Holding
PRAX
+6.14%
3M Return

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Frequently Asked Questions

What is Praxis Precision Medicines Inc (PRAX) stock price today?

The current price of PRAX is 309.91 USD — it has increased 0.29

What is Praxis Precision Medicines Inc (PRAX)'s business?

Praxis Precision Medicines, Inc. is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms, using its understanding of shared biological targets and circuits in the brain. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is an efficient, targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company’s product candidates include ulixacaltamide, vormatrigine, relutrigine, PRAX-080, and others.

What is the price predicton of PRAX Stock?

Wall Street analysts forecast PRAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRAX is456.71 USD with a low forecast of 95.00 USD and a high forecast of 843.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Praxis Precision Medicines Inc (PRAX)'s revenue for the last quarter?

Praxis Precision Medicines Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Praxis Precision Medicines Inc (PRAX)'s earnings per share (EPS) for the last quarter?

Praxis Precision Medicines Inc. EPS for the last quarter amounts to -3.49 USD, increased 19.11

How many employees does Praxis Precision Medicines Inc (PRAX). have?

Praxis Precision Medicines Inc (PRAX) has 168 emplpoyees as of March 11 2026.

What is Praxis Precision Medicines Inc (PRAX) market cap?

Today PRAX has the market capitalization of 8.63B USD.