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PRAX Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
289.670
Open
280.600
VWAP
282.05
Vol
698.57K
Mkt Cap
7.87B
Low
274.160
Amount
197.03M
EV/EBITDA(TTM)
--
Total Shares
27.88M
EV
6.74B
EV/OCF(TTM)
--
P/S(TTM)
--
Praxis Precision Medicines, Inc. is an integrated, central nervous system (CNS) precision neuroscience biopharmaceutical company, translating insights from genetic epilepsies into the development of therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is a targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company's product candidates include Ulixacaltamide, Vormatrigine, Relutrigine, PRAX-080, Elsunersen, and others.
Show More

Events Timeline

(ET)
2026-06-02
12:10:00
Praxis Precision Shares Drop 15.4% to $283.47
select

News

seekingalpha
6.0
06-18seekingalpha
RBC Capital Markets Initiates Praxis Precision with Outperform Rating
  • Positive Market Outlook: RBC Capital Markets has initiated coverage on Praxis Precision Markets with an outperform rating, citing a recent pullback as a good entry point, and they expect a transformative next six months with a price target of $449, representing a 66% upside from the June 17 close.
  • Significant Sales Potential: Analyst Leonid Timashev highlighted that ulixacaltamide has a sales potential exceeding $4.3 billion for essential tremor, acknowledging regulatory risks but noting strong physician willingness to prescribe, indicating a large unmet need in the market.
  • Long-term Revenue Prospects: Timashev also mentioned that Praxis could achieve over $7.8 billion in revenue by 2035, which is attractive to investors and suggests strong growth potential in future market competition.
  • New Drug Development Opportunities: For genetically driven epilepsy, Timashev sees a high probability of success for relutrigine, while elsunersen could contribute an additional $200 million for the most severe patients, although feedback indicates not all families would opt for this antisense oligonucleotide treatment.
CNBC
6.0
06-18CNBC
Latest Wall Street Rating Updates
  • Apple Rating Reaffirmed: Bank of America reiterates Apple as a buy, believing that price increases are already reflected in the stock, anticipating that rising memory costs will force Apple to raise prices, impacting future earnings performance.
  • Nice Upgrade: DA Davidson upgrades Nice from neutral to buy, maintaining a $110 price target, arguing that concerns about AI disruption are overblown, suggesting a more optimistic outlook that could boost the company's stock price.
  • Immix Biopharma Initiation: Bank of America initiates coverage of Immix Biopharma with a buy rating and a $27 price target, citing the company's differentiated product offerings as a significant growth driver.
  • Salesforce Upgrade: Monness Crespi Hardt upgrades Salesforce from neutral to buy with a $200 price target, based on its depressed valuation, strong cash flow generation, and support for customer transformation, which are expected to drive stock price increases.
NASDAQ.COM
6.0
06-04NASDAQ.COM
Wedbush Lowers Praxis Price Target to $162 After POWER1 Miss
  • POWER1 Study Failure: Praxis Precision Medicines Inc.'s POWER1 study failed to meet its primary endpoint, prompting Wedbush to lower its 12-month price target from $355 to $162 while maintaining an Underperform rating, reflecting concerns over clinical development uncertainty.
  • Need for Dose Adjustment: Although a more pronounced seizure reduction was observed at the 30mg dose, it still did not meet the prespecified endpoint, leading Praxis to pause enrollment in the POWER2 study to reassess potential modifications, indicating a cautious approach to future research directions.
  • Positive Outlook for IDEAYA: Wedbush reaffirmed its Outperform rating on IDEAYA Biosciences with a price target of $58, based on positive results from the OptimUM-02 study, which demonstrated significant improvement in progression-free survival with Darovasertib plus Crizotinib compared to the control group.
  • Strategic Deal for Edgewise: Edgewise Therapeutics reached a $1.55 billion agreement with Servier to sell all rights to Sevasemten, providing non-dilutive capital to strengthen its financial position and support a strategic focus on cardiac programs.
NASDAQ.COM
4.5
06-02NASDAQ.COM
US Stocks Close at All-Time Highs as AI Investments Surge
  • Strong Market Performance: The S&P 500 rose by 0.13%, the Dow Jones by 0.45%, and the Nasdaq 100 by 0.48%, with all three indices reaching new all-time highs, reflecting strong investor confidence in tech stocks amid a surge in AI investments.
  • Marvell Technology Soars: Marvell Technology's stock surged over 32% after Nvidia CEO Jensen Huang predicted the company would be the next to achieve a $1 trillion valuation, significantly boosting investor confidence in its future growth prospects.
  • Hewlett Packard Enterprise's Strong Earnings: Hewlett Packard Enterprise's stock jumped more than 19% after reporting Q2 adjusted EPS of 79 cents, well above the consensus estimate of 54 cents, and raising its full-year adjusted EPS forecast to $3.35-$3.45, reflecting robust demand driven by AI.
  • Labor Market Strength: US April JOLTS job openings unexpectedly rose by 731,000 to a 23-month high of 7.618 million, surpassing expectations of a decline to 6.866 million, indicating resilience in the labor market and further propelling stock market gains.
NASDAQ.COM
4.5
06-02NASDAQ.COM
US Stocks Rise Slightly, Tech Stocks Show Strong Rebound
  • Strong Labor Market: US April JOLTS job openings unexpectedly rose by 731,000 to a 23-month high of 7.618 million, surpassing expectations of 6.866 million, indicating labor market resilience and driving stock market gains, particularly in tech stocks.
  • Tech Stock Surge: Hewlett-Packard Enterprise (HPE) shares surged over 25% after reporting Q2 adjusted EPS of 79 cents, significantly above the consensus estimate of 54 cents, and raising its full-year adjusted EPS forecast to $3.35-$3.45, reflecting robust growth in AI-driven demand.
  • Market Volatility Factors: Despite overall market gains, initial declines occurred due to uncertainty surrounding a US-Iran ceasefire, with oil prices slightly down as President Trump stated negotiations with Iran are progressing “at a rapid pace,” potentially affecting investor sentiment.
  • Software Stocks Under Pressure: Intuit (INTU) saw its stock drop over 10% after Goldman Sachs downgraded it to sell with a price target of $276, leading to a broader decline in the software sector, highlighting a divergence in market performance among tech stocks.
NASDAQ.COM
4.5
06-02NASDAQ.COM
US Stocks Dip Slightly Amid Tech Sector Pressure
  • Market Weakness: The S&P 500 index fell by 0.20%, the Dow Jones by 0.23%, and the Nasdaq 100 by 0.33%, indicating investor uncertainty regarding the US-Iran ceasefire prospects, which may dampen market confidence.
  • Tech Sector Volatility: Software stocks faced declines, with Intuit dropping over 8% following a downgrade from Goldman Sachs, while Hewlett-Packard Enterprise surged over 33% due to soaring AI demand, highlighting a divergence within the tech industry.
  • Inflation Expectations Shift: Hawkish comments from Cleveland Fed President raised rate hike expectations, with the 10-year T-note yield dropping to 4.422%, reflecting growing investor concerns about persistent inflation.
  • Overseas Market Dynamics: European markets showed mixed results, with Eurozone May CPI rising 3.2% year-on-year, exceeding expectations and indicating signs of economic recovery, while China's stock market rebounded, reflecting the complexities of the global economy.
Wall Street analysts forecast PRAX stock price to rise
15 Analyst Rating
Wall Street analysts forecast PRAX stock price to rise
14 Buy
0 Hold
1 Sell
Strong Buy
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
Current: 0.000
sliders
Low
95.00
Averages
456.71
High
843.00
RBC Capital
Leonid Timashev
Outperform
initiated
$449
AI Analysis
2026-06-17
New
Reason
RBC Capital
Leonid Timashev
Price Target
$449
AI Analysis
2026-06-17
New
initiated
Outperform
Reason
RBC Capital analyst Leonid Timashev initiated coverage of Praxis Precision with an Outperform rating and $449 price target. The firm believes think ulixacaltamide has a "reasonable likelihood" of achieving over $4.3B in sales. RBC's regulatory checks suggest the essential tremor treatment can make it to market, and there is a "large unmet need and strong desire to prescribe" among physicians, the analyst tells investors in a research note. The firm sees a good entry point with the shares down 25% from recent highs.
BTIG
Buy
downgrade
$843 -> $810
2026-06-02
Reason
BTIG
Price Target
$843 -> $810
2026-06-02
downgrade
Buy
Reason
BTIG lowered the firm's price target on Praxis Precision to $810 from $843 and keeps a Buy rating on the shares. The company's reported a topline miss on the Phase 2/3 POWER1 trial of vormatrigine, but while this was a setback, the vormatrigine program is not without a recoverable path, the analyst tells investors in a research note. The 50% response rate secondary measure was met, seizure reduction was more pronounced in the second half of the study on the higher 30 mg dose, adverse event-related discontinuations were less than 10%, and approximately 90% of vormatrigine-arm patients transitioned into the open-label extension and remain there, the firm added.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for PRAX
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Valuation Metrics

The current forward P/E ratio for Praxis Precision Medicines Inc (PRAX.O) is 0.00, compared to its 5-year average forward P/E of -3.93. For a more detailed relative valuation and DCF analysis to assess Praxis Precision Medicines Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-3.93
Current PE
0.00
Overvalued PE
-0.46
Undervalued PE
-7.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-2.37
Current EV/EBITDA
0.00
Overvalued EV/EBITDA
0.99
Undervalued EV/EBITDA
-5.73

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
669.10
Current PS
23.01
Overvalued PS
2070.58
Undervalued PS
-732.37

Financials

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Whales Holding PRAX

H
Hood River Capital Management LLC
Holding
PRAX
+31.69%
3M Return
D
Deerfield Management Company, L.P.
Holding
PRAX
+20.88%
3M Return
D
Driehaus Capital Management LLC
Holding
PRAX
+18.55%
3M Return
C
Caption Management, LLC
Holding
PRAX
+17.06%
3M Return
J
Janus Henderson Group plc
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PRAX
+15.85%
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A
Algert Global LLC
Holding
PRAX
+14.84%
3M Return

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Frequently Asked Questions

What is Praxis Precision Medicines Inc (PRAX) stock price today?

The current price of PRAX is 282.31 USD — it has increased 4.56

What is Praxis Precision Medicines Inc (PRAX)'s business?

Praxis Precision Medicines, Inc. is an integrated, central nervous system (CNS) precision neuroscience biopharmaceutical company, translating insights from genetic epilepsies into the development of therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance. The Company is applying genetic insights to the discovery and development of therapies for neurological disorders through two platforms. Its platform includes Cerebrum, a small-molecule platform, which utilizes deep understanding of neuronal excitability and neuronal networks and applies a series of computational and experimental tools to develop orally available precision therapies, and Solidus, an antisense oligonucleotide platform, is a targeted precision medicine discovery and development engine anchored on a proprietary, computational methodology. The Company's product candidates include Ulixacaltamide, Vormatrigine, Relutrigine, PRAX-080, Elsunersen, and others.

What is the price predicton of PRAX Stock?

Wall Street analysts forecast PRAX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for PRAX is456.71 USD with a low forecast of 95.00 USD and a high forecast of 843.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Praxis Precision Medicines Inc (PRAX)'s revenue for the last quarter?

Praxis Precision Medicines Inc revenue for the last quarter amounts to 0.00 USD, decreased

What is Praxis Precision Medicines Inc (PRAX)'s earnings per share (EPS) for the last quarter?

Praxis Precision Medicines Inc. EPS for the last quarter amounts to -3.20 USD, decreased -2.74

How many employees does Praxis Precision Medicines Inc (PRAX). have?

Praxis Precision Medicines Inc (PRAX) has 168 emplpoyees as of June 19 2026.

What is Praxis Precision Medicines Inc (PRAX) market cap?

Today PRAX has the market capitalization of 7.87B USD.