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JAZZ Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
231.142
Open
226.200
VWAP
229.12
Vol
845.91K
Mkt Cap
14.45B
Low
226.200
Amount
193.82M
EV/EBITDA(TTM)
11.13
Total Shares
62.82M
EV
16.69B
EV/OCF(TTM)
12.51
P/S(TTM)
3.18
Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma.
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Events Timeline

(ET)
2026-06-17
07:30:00
Jazz Pharmaceuticals Collaborates with AbCellera to Develop Next-Generation Antibodies
select
2026-06-17
07:30:00
Jazz Pharmaceuticals Collaborates with AbCellera to Develop Next-Generation Antibodies
select
2026-06-12 (ET)
2026-06-12
09:30:00
S&P Futures Rise as Oil Prices Drop, Boosting Market
select
2026-05-27 (ET)
2026-05-27
17:10:00
Jazz Pharmaceuticals Announces Phase 3 Trial Results for Ziihera
select

News

Fool
9.0
06-23Fool
Jazz Pharmaceuticals' Zepzelca Phase 3 Trial Fails to Meet Primary Endpoint
  • Trial Outcome: Jazz Pharmaceuticals' Zepzelca failed to meet the primary endpoint of overall survival in its Phase 3 trial for small-cell lung cancer, as patients treated with Zepzelca did not live longer than those receiving standard treatments; however, this negative result is not expected to significantly impact the company's long-term investment thesis.
  • Shifting Market Opportunities: In 2025, the FDA granted full approval for Zepzelca in combination with Roche's Tecentriq as a first-line maintenance treatment for extensive-stage small-cell lung cancer, based on a Phase 3 study showing a 46% reduction in disease progression or death risk, indicating a shift towards more promising commercial opportunities.
  • Sales Growth: Zepzelca's sales surged 60% year-over-year to approximately $101 million in Q1 2026, driven by increasing adoption in the first-line maintenance setting, with management asserting that the recent trial results will not affect the 2026 financial outlook.
  • Diversification Strategy: Although a failed Phase 3 trial can lead to significant revenue losses for a pharmaceutical company, Jazz's diversified product portfolio mitigates this risk, as the company generated around $4.3 billion in total revenue in 2025, with Zepzelca contributing only 7%, while Xywav and Epidiolex generated $1.7 billion and $1.1 billion, respectively.
NASDAQ.COM
8.5
06-19NASDAQ.COM
Biotech Sector Sees FDA Approvals and Layoffs
  • FDA Drug Approval: Spero Therapeutics and GSK announced FDA approval for Utebzi, the first oral carbapenem for complicated urinary tract infections, marking a significant advancement in treatment options for adults with limited choices, which is expected to enhance market share.
  • Expanded Injectable Indication: AbbVie's SKINVIVE received FDA approval to improve neck lines in adults over 21, with pivotal studies showing nearly 75% of patients achieving significant improvement at one month, further solidifying AbbVie's leadership in the aesthetics market.
  • Strategic Acquisition: Biogen agreed to acquire RayThera for up to $1 billion to expand its immunology portfolio, with the transaction expected to close in Q3 2026, enhancing Biogen's competitive position in the immunotherapy space.
  • Layoff Plans: Neumora Therapeutics announced a 35% workforce reduction to save $10 million annually, reflecting strategic adjustments following the failure to meet primary endpoints in clinical trials, aimed at extending cash runway.
NASDAQ.COM
7.5
06-17NASDAQ.COM
Jazz Pharmaceuticals and AbCellera Collaborate on Antibody Development
  • Collaboration Overview: Jazz Pharmaceuticals has entered into a research collaboration and license agreement with AbCellera Biologics to develop next-generation T-cell engaging multispecific antibodies targeting gastrointestinal cancers and other solid tumors, leveraging Jazz's oncology expertise and AbCellera's antibody discovery platform.
  • Financial Terms: Under the agreement, AbCellera will receive $56 million in upfront payments for the first two programs and an additional $28 million upon the initiation of the third program, with potential milestone payments of up to $792 million per program if Jazz advances them into development, along with tiered royalties on future sales.
  • Clinical Development Potential: Jazz will hold exclusive worldwide rights to develop and commercialize any resulting antibodies, which is expected to propel potential best-in-class antibody therapies into clinical development, thereby enhancing its market position in oncology.
  • Strategic Significance: This collaboration aligns with Jazz's oncology strategy and expands its focus on GI cancers, while AbCellera's T-cell engager platform is set to facilitate the development of novel multispecific antibodies aimed at driving targeted immune activation against hard-to-treat cancers, fostering innovation in immunotherapy.
seekingalpha
7.5
06-17seekingalpha
Jazz Pharmaceuticals and AbCellera Sign $848M Agreement for Antibody Development
  • Significant Agreement Value: Jazz Pharmaceuticals has signed an agreement with AbCellera potentially worth up to $848 million, which includes an upfront payment of $56 million and up to $792 million in milestone payments, reflecting strong confidence in next-generation antibody development.
  • Focused R&D Objectives: The deal centers on leveraging AbCellera's antibody discovery engine to develop multispecific antibodies targeting gastrointestinal cancers and other solid tumors, aiming to address current treatment gaps and enhance patient options.
  • Commitment to Project Advancement: AbCellera is committed to conducting discovery and early-stage research for two programs and initiating a third program within a year, ensuring continuous progress in R&D and strengthening its market competitiveness.
  • Commercialization Rights Option: Jazz Pharmaceuticals holds an option for each research program, which, if exercised along with the payment of an option fee, grants exclusive worldwide commercialization rights, providing a crucial safeguard for future revenue growth.
PRnewswire
7.5
06-17PRnewswire
Jazz Pharmaceuticals Partners with AbCellera for Antibody Development
  • Significant Financial Commitment: The collaboration between Jazz Pharmaceuticals and AbCellera includes $56 million in upfront payments and up to $792 million in potential option fees and milestone payments, reflecting strong confidence in antibody development from both parties.
  • Exclusive Development Rights: Jazz has secured exclusive rights to develop and commercialize therapeutic antibodies resulting from the collaboration, which not only enhances its competitive position in oncology but also strategically expands its focus on rare diseases.
  • Technological Platform Advantage: AbCellera's T-cell engager platform offers a fully integrated capability from discovery to clinical manufacturing for developing multispecific antibodies for difficult-to-treat cancers, which is expected to significantly improve outcomes compared to existing treatment options.
  • Expanded R&D Plans: Under the agreement, AbCellera will conduct discovery and early-stage research for two initial programs, with a commitment to start a third program within 12 months, indicating strong potential for long-term collaboration in cancer treatment development.
Newsfilter
7.5
06-17Newsfilter
Jazz Pharmaceuticals Partners with AbCellera for Antibody Development
  • Collaboration Agreement Details: Jazz Pharmaceuticals has entered into a collaboration with AbCellera involving $56 million in upfront payments and potential option fees and milestone payments totaling up to $792 million, indicating a significant partnership in antibody development.
  • Focused Research Direction: The collaboration aims to develop next-generation T-cell engaging multispecific antibodies targeting various gastrointestinal cancers and other solid tumors, aligning with Jazz's strategic focus on rare diseases and enhancing cancer treatment outcomes.
  • Technological Platform Advantage: AbCellera's T-cell engager platform offers comprehensive capabilities from discovery to clinical manufacturing, incorporating novel CD3-binding antibodies and multispecific protein engineering technology, which is expected to significantly improve existing cancer treatment efficacy.
  • Future Development Potential: The agreement allows Jazz to opt for multiple research programs, which could yield substantial milestone payments and sales royalties for AbCellera, further solidifying its competitive position in the biopharmaceutical market.
Wall Street analysts forecast JAZZ stock price to rise
13 Analyst Rating
Wall Street analysts forecast JAZZ stock price to rise
12 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
188.00
Averages
218.92
High
263.00
Current: 0.000
sliders
Low
188.00
Averages
218.92
High
263.00
Barclays
NULL
to
Overweight
maintain
$234 -> $253
AI Analysis
2026-05-27
Reason
Barclays
Price Target
$234 -> $253
AI Analysis
2026-05-27
maintain
NULL
to
Overweight
Reason
Barclays raised the firm's price target on Jazz Pharmaceuticals to $253 from $234 and keeps an Overweight rating on the shares. An expert call indicates Jazz has "robust" patent estate and exclusivities to likely fend off generic Xywav challengers until at least 2028, the analyst tells investors in a research note.
UBS
Ashwani Verma
Neutral -> Buy
upgrade
$188 -> $307
2026-05-19
Reason
UBS
Ashwani Verma
Price Target
$188 -> $307
2026-05-19
upgrade
Neutral -> Buy
Reason
UBS analyst Ashwani Verma upgraded Jazz Pharmaceuticals to Buy from Neutral with a price target of $307, up from $188. The firm cites improved confidence in Jazz's base business and Ziihera's commercial potential for the upgrade. UBS sees better than expected execution following the Q1 report and says the "strong" Phase 3 HERIZON gastroesophageal adenocarcinoma data support "rapid" Ziihera uptake. The firm now models for 10% annual revenue and 11% annual earnings growth, which is ahead of consensus. Jazz offers a "double-digit compounder earnings profile," contends UBS.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for JAZZ
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Valuation Metrics

The current forward P/E ratio for Jazz Pharmaceuticals PLC (JAZZ.O) is 12.55, compared to its 5-year average forward P/E of 7.70. For a more detailed relative valuation and DCF analysis to assess Jazz Pharmaceuticals PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
7.70
Current PE
12.55
Overvalued PE
9.95
Undervalued PE
5.46

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
8.51
Current EV/EBITDA
8.29
Overvalued EV/EBITDA
12.67
Undervalued EV/EBITDA
4.34

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
2.15
Current PS
2.99
Overvalued PS
2.56
Undervalued PS
1.75

Financials

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Whales Holding JAZZ

L
Logos Global Management, L.P.
Holding
JAZZ
+30.19%
3M Return
C
Crestline Investors Inc.
Holding
JAZZ
+29.79%
3M Return
P
Perceptive Advisors LLC
Holding
JAZZ
+29.01%
3M Return
G
GMT Capital Corp.
Holding
JAZZ
+28.43%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
JAZZ
+25.43%
3M Return
S
Systematic Financial Management LP
Holding
JAZZ
+24.68%
3M Return

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Frequently Asked Questions

What is Jazz Pharmaceuticals PLC (JAZZ) stock price today?

The current price of JAZZ is 230.02 USD — it has increased 1.69

What is Jazz Pharmaceuticals PLC (JAZZ)'s business?

Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma.

What is the price predicton of JAZZ Stock?

Wall Street analysts forecast JAZZ stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for JAZZ is218.92 USD with a low forecast of 188.00 USD and a high forecast of 263.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Jazz Pharmaceuticals PLC (JAZZ)'s revenue for the last quarter?

Jazz Pharmaceuticals PLC revenue for the last quarter amounts to 1.07B USD, increased 19.05

What is Jazz Pharmaceuticals PLC (JAZZ)'s earnings per share (EPS) for the last quarter?

Jazz Pharmaceuticals PLC. EPS for the last quarter amounts to 4.43 USD, decreased -391.45

How many employees does Jazz Pharmaceuticals PLC (JAZZ). have?

Jazz Pharmaceuticals PLC (JAZZ) has 2890 emplpoyees as of June 27 2026.

What is Jazz Pharmaceuticals PLC (JAZZ) market cap?

Today JAZZ has the market capitalization of 14.45B USD.