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JAZZ Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

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High
231.490
Open
226.110
VWAP
229.14
Vol
910.44K
Mkt Cap
14.19B
Low
224.990
Amount
208.62M
EV/EBITDA(TTM)
11.11
Total Shares
62.74M
EV
16.67B
EV/OCF(TTM)
12.49
P/S(TTM)
3.18
Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma.
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Events Timeline

(ET)
2026-05-27
17:10:00
Jazz Pharmaceuticals Announces Phase 3 Trial Results for Ziihera
select
2026-05-19 (ET)
2026-05-19
16:30:00
Major Averages Decline for Second Day, Tech Stocks Lead Losses
select
2026-05-19
12:10:00
Major Averages Decline for Second Day, Tech Stocks Lead
select

News

PRnewswire
2.0
05-27PRnewswire
Zanidatamab Shows Breakthrough Efficacy in HER2-Positive Cancer Treatments
  • Clinical Trial Results: Jazz Pharmaceuticals announced that the Phase 3 HERIZON-GEA-01 trial results demonstrate unprecedented progression-free survival (PFS) and overall survival (OS) outcomes for zanidatamab combined with chemotherapy in patients with HER2-positive gastroesophageal adenocarcinoma, providing a new treatment option for patients.
  • Subgroup Analysis: Expanded subgroup analyses indicate that zanidatamab's efficacy is significant even in PD-L1-negative patients, showcasing its consistent therapeutic benefits across different biomarker backgrounds, which may alter treatment standards in clinical practice.
  • Safety Analysis: Safety analyses consistent with known safety profiles reveal that gastrointestinal adverse events occurred but were generally manageable, with a low rate of treatment discontinuation due to adverse reactions, indicating good tolerability of zanidatamab combined with chemotherapy.
  • Future Outlook: Jazz has submitted the HERIZON-GEA-01 results to the National Comprehensive Cancer Network (NCCN) for inclusion in clinical practice guidelines, aiming to position zanidatamab as a first-line treatment choice for HER2-positive gastroesophageal adenocarcinoma.
Newsfilter
9.0
05-27Newsfilter
Zanidatamab Shows Breakthrough Efficacy in HER2-Positive Cancer
  • Clinical Trial Results: Jazz Pharmaceuticals announced that the HERIZON-GEA-01 Phase 3 trial results show that the combination of Zanidatamab with chemotherapy yields a median progression-free survival (PFS) of 12.4 months, significantly higher than the 8.1 months seen with traditional trastuzumab plus chemotherapy, indicating its potential in treating HER2-positive gastroesophageal adenocarcinoma.
  • Survival Improvement: The combination of Zanidatamab with Tislelizumab and chemotherapy also demonstrated a statistically significant median overall survival (OS) of 26.4 months compared to 19.2 months for trastuzumab plus chemotherapy, highlighting its advantage in improving patient survival rates.
  • Consistency in Subgroup Analysis: Expanded subgroup analyses indicate that the efficacy of Zanidatamab remains consistent regardless of PD-L1 expression status, particularly in PD-L1-negative patients, where the median OS was 29.7 months, far exceeding the 15.8 months for trastuzumab, emphasizing its broad applicability.
  • Safety Profile: Safety analyses of Zanidatamab align with the known safety profiles of its individual components, with 48% of patients experiencing severe diarrhea; however, most events were time-limited and infrequently led to treatment discontinuation, suggesting its acceptability in clinical use.
seekingalpha
6.0
05-19seekingalpha
UBS Upgrades Jazz Pharmaceuticals to Buy, Highlights Ziihera's Potential
  • Rating Upgrade: UBS upgraded Jazz Pharmaceuticals from Neutral to Buy, primarily based on the commercial potential of Ziihera in biliary tract cancer treatment, indicating increasing market confidence in the drug's prospects.
  • FDA Application Progress: Jazz's supplemental Biologics License Application has been accepted by the FDA, seeking to expand Ziihera's indication in gastroesophageal adenocarcinoma, with a decision expected on August 25, 2026, further enhancing investor expectations for the company's future.
  • Sales Growth: Ziihera generated $13.3 million in revenue in Q1 2026, a significant increase from $9 million in Q4 2025, reflecting accelerated sales that have positively impacted the company's performance.
  • Financial Forecast Revision: UBS analyst revised Jazz's revenue and EPS CAGR estimates for 2026-2030 to 10% and 11%, respectively, surpassing consensus estimates of 7% and 6%, demonstrating an optimistic outlook on the company's future growth.
CNBC
6.0
05-19CNBC
Latest Wall Street Ratings and Price Target Adjustments
  • Micron Price Target Increase: Citigroup raised Micron Technology's price target from $425 to $840, anticipating a 40% increase in DRAM prices in Q2, which will significantly enhance its market competitiveness.
  • Jazz Pharmaceuticals Upgrade: UBS upgraded Jazz Pharmaceuticals from Neutral to Buy and raised its price target from $188 to $307, driven by increased confidence in the commercial potential of its cancer drug Ziihera, which is expected to boost company performance.
  • Nvidia Price Target Boost: HSBC raised Nvidia's price target from $295 to $325, expecting the company to exceed market expectations in its upcoming earnings report, further enhancing its profitability.
  • Costco Price Target Increase: Oppenheimer raised Costco's price target from $1,100 to $1,160, believing that its defensive characteristics and superior value proposition will continue to drive market share growth, with potential catalysts for a special dividend or stock split.
PRnewswire
1.0
05-12PRnewswire
Jazz Pharmaceuticals to Participate in Investor Conferences
  • Investor Conference Participation: Jazz Pharmaceuticals announced that its management will participate in several investor conferences, highlighting the company's commitment to investor communication aimed at boosting market confidence and attracting potential investors.
  • Webcast Availability: Audio webcasts of the conferences will be available via the Investors section of Jazz Pharmaceuticals' website, ensuring that investors can access real-time updates on the company's latest developments, enhancing transparency and information sharing.
  • Focus on Patient Needs: Jazz Pharmaceuticals is dedicated to developing life-changing medicines for rare diseases, emphasizing its innovative capabilities in areas with limited treatment options, further solidifying its leadership position in the biopharmaceutical industry.
  • Global Business Presence: Headquartered in Dublin, Ireland, the company has research and development laboratories and manufacturing facilities in multiple countries, showcasing its global business strategy and commitment to serving patients worldwide.
seekingalpha
6.5
05-07seekingalpha
Foreign Healthcare Stocks Show Strong Quant Ratings
  • Top Quant Ratings: Jazz Pharmaceuticals (JAZZ) leads with a 4.86 Quant score, showcasing its strong competitive position as one of the highest-rated specialty pharma companies globally, driven by a diversified neuroscience and oncology portfolio.
  • Pipeline Excellence: AstraZeneca (AZN) follows closely with a 4.75 rating, reflecting the UK giant's exceptional pipeline execution and its status as one of the few mega-cap pharma companies currently favored by the Quant system.
  • Focus on Specialty Drugs: Japanese pharma Astellas (ALPMY) and Swedish Orphan Biovitrum (SWOBY) round out the top four with scores of 4.64 and 4.63, respectively, highlighting the significance of specialty and orphan drug pipelines in the foreign healthcare sector's appeal.
  • Market Disparity: While the top four stocks excel, Sandoz (SDZNY) and Galderma (GALDY) sit lower on the list with scores of 3.35, serving as a reminder that not all foreign healthcare stocks receive equal treatment from the Quant system, indicating a clear market disparity.
Wall Street analysts forecast JAZZ stock price to rise
13 Analyst Rating
Wall Street analysts forecast JAZZ stock price to rise
12 Buy
1 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
188.00
Averages
218.92
High
263.00
Current: 0.000
sliders
Low
188.00
Averages
218.92
High
263.00
Barclays
NULL
to
Overweight
maintain
$234 -> $253
AI Analysis
2026-05-27
Reason
Barclays
Price Target
$234 -> $253
AI Analysis
2026-05-27
maintain
NULL
to
Overweight
Reason
Barclays raised the firm's price target on Jazz Pharmaceuticals to $253 from $234 and keeps an Overweight rating on the shares. An expert call indicates Jazz has "robust" patent estate and exclusivities to likely fend off generic Xywav challengers until at least 2028, the analyst tells investors in a research note.
UBS
Ashwani Verma
Neutral -> Buy
upgrade
$188 -> $307
2026-05-19
Reason
UBS
Ashwani Verma
Price Target
$188 -> $307
2026-05-19
upgrade
Neutral -> Buy
Reason
UBS analyst Ashwani Verma upgraded Jazz Pharmaceuticals to Buy from Neutral with a price target of $307, up from $188. The firm cites improved confidence in Jazz's base business and Ziihera's commercial potential for the upgrade. UBS sees better than expected execution following the Q1 report and says the "strong" Phase 3 HERIZON gastroesophageal adenocarcinoma data support "rapid" Ziihera uptake. The firm now models for 10% annual revenue and 11% annual earnings growth, which is ahead of consensus. Jazz offers a "double-digit compounder earnings profile," contends UBS.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for JAZZ
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Valuation Metrics

The current forward P/E ratio for Jazz Pharmaceuticals PLC (JAZZ.O) is 12.69, compared to its 5-year average forward P/E of 7.71. For a more detailed relative valuation and DCF analysis to assess Jazz Pharmaceuticals PLC's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
7.71
Current PE
12.69
Overvalued PE
9.95
Undervalued PE
5.46

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
8.50
Current EV/EBITDA
8.34
Overvalued EV/EBITDA
12.67
Undervalued EV/EBITDA
4.34

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
2.16
Current PS
3.01
Overvalued PS
2.57
Undervalued PS
1.74

Financials

AI Analysis
Annual
Quarterly

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Whales Holding JAZZ

S
Systematic Financial Management LP
Holding
JAZZ
+21.00%
3M Return
G
GMT Capital Corp.
Holding
JAZZ
+18.70%
3M Return
H
Hennion & Walsh Asset Management, Inc.
Holding
JAZZ
+13.63%
3M Return
G
GW&K Investment Management, LLC
Holding
JAZZ
+12.96%
3M Return
C
Crestline Investors Inc.
Holding
JAZZ
+12.15%
3M Return
L
LSV Asset Management
Holding
JAZZ
+11.90%
3M Return

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Frequently Asked Questions

What is Jazz Pharmaceuticals PLC (JAZZ) stock price today?

The current price of JAZZ is 230.93 USD — it has increased 2.13

What is Jazz Pharmaceuticals PLC (JAZZ)'s business?

Jazz Pharmaceuticals plc is a global biopharmaceutical company. It is engaged in developing medicines for people with serious diseases, often with limited or no therapeutic options. It has a diverse portfolio of marketed medicines, including therapies for sleep disorders and epilepsy, and a portfolio of cancer treatments. Its lead-marketed products include Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution, Epidiolex (cannabidiol) oral solution, Rylaze (asparaginase erwinia chrysanthemi (recombinant)-rywn), Zepzelca (lurbinectedin), Ziihera (zanidatamab-hrii), and Enrylaze (recombinant crisantaspase). Its product candidates include Zanidatamab, Vyxeos, JZP815, JZP898, JZP441, and others. Xywav is used for the treatment of cataplexy or EDS in patients seven years of age and older with narcolepsy. The Company, through Chimerix, Inc., also owns a clinical asset, dordaviprone, a novel small molecule treatment in development for H3 K27M-mutant diffuse glioma.

What is the price predicton of JAZZ Stock?

Wall Street analysts forecast JAZZ stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for JAZZ is218.92 USD with a low forecast of 188.00 USD and a high forecast of 263.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Jazz Pharmaceuticals PLC (JAZZ)'s revenue for the last quarter?

Jazz Pharmaceuticals PLC revenue for the last quarter amounts to 1.07B USD, increased 19.05

What is Jazz Pharmaceuticals PLC (JAZZ)'s earnings per share (EPS) for the last quarter?

Jazz Pharmaceuticals PLC. EPS for the last quarter amounts to 4.43 USD, decreased -391.45

How many employees does Jazz Pharmaceuticals PLC (JAZZ). have?

Jazz Pharmaceuticals PLC (JAZZ) has 2890 emplpoyees as of June 03 2026.

What is Jazz Pharmaceuticals PLC (JAZZ) market cap?

Today JAZZ has the market capitalization of 14.19B USD.