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NBIX Overview

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0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
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ET
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Intellectia

Loading chart...

High
161.330
Open
160.010
VWAP
158.64
Vol
2.72M
Mkt Cap
15.92B
Low
156.310
Amount
431.23M
EV/EBITDA(TTM)
17.62
Total Shares
100.55M
EV
14.60B
EV/OCF(TTM)
16.90
P/S(TTM)
5.24
Neurocrine Biosciences, Inc. is a neuroscience-focused, biopharmaceutical company. It is engaged in discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. Its diverse portfolio includes the United States Food and Drug Administration-approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, endometriosis and uterine fibroids, as well as a robust pipeline, including multiple compounds in mid-to late-phase clinical development across its core therapeutic areas. Its first-in-class commercial portfolio includes INGREZZA (valbenazine) and CRENESSITY (crinecerfont). It also offers VYKAT XR (diazoxide choline) extended-release tablets, for the treatment of hyperphagia in adults and pediatric patients four years of age and older with Prader-Willi syndrome (PWS). Its pipeline includes direclidine / (M4 Agonist), osavampator॥ / (AMPA PAM) and others.
Show More

Events Timeline

(ET)
2026-06-15
16:30:00
Soleno Therapeutics Releases VYKAT XR Study Data
select
2026-06-15
16:30:00
Neurocrine Reports Clinical Findings on 11beta-Hydroxylase Deficiency
select
2026-06-15
09:00:00
Neurocrine Biosciences Releases Crenessity Study Data Showing Improved Cardiometabolic Outcomes
select

News

NASDAQ.COM
8.5
06-19NASDAQ.COM
Biotech Sector Sees FDA Approvals and Layoffs
  • FDA Drug Approval: Spero Therapeutics and GSK announced FDA approval for Utebzi, the first oral carbapenem for complicated urinary tract infections, marking a significant advancement in treatment options for adults with limited choices, which is expected to enhance market share.
  • Expanded Injectable Indication: AbbVie's SKINVIVE received FDA approval to improve neck lines in adults over 21, with pivotal studies showing nearly 75% of patients achieving significant improvement at one month, further solidifying AbbVie's leadership in the aesthetics market.
  • Strategic Acquisition: Biogen agreed to acquire RayThera for up to $1 billion to expand its immunology portfolio, with the transaction expected to close in Q3 2026, enhancing Biogen's competitive position in the immunotherapy space.
  • Layoff Plans: Neumora Therapeutics announced a 35% workforce reduction to save $10 million annually, reflecting strategic adjustments following the failure to meet primary endpoints in clinical trials, aimed at extending cash runway.
PRnewswire
9.0
06-15PRnewswire
Long-Term Efficacy of VYKAT XR for Prader-Willi Syndrome
  • Significant Treatment Effects: In a two-year study, participants resuming VYKAT XR showed durable improvements in hyperphagia and behavioral symptoms, reinforcing the drug's efficacy and safety as a long-term treatment for Prader-Willi syndrome (PWS).
  • Clinical Trial Data: Results from Study C614 involving 77 participants indicated that those who resumed treatment experienced significant recovery in hyperphagia symptoms, while those on continuous therapy maintained notable improvements in hyperphagia and other PWS-related behaviors.
  • Long-Term Follow-Up Study: Compared to 229 natural history controls, VYKAT XR demonstrated statistically significant improvements in hyperphagia scores at all evaluated time points over three years, highlighting the drug's sustained efficacy.
  • Behavioral Improvement Analysis: Analysis of PWSP data from 105 VYKAT XR-treated participants revealed significant improvements across all six behavioral domains, further validating its potential application in PWS patients.
PRnewswire
9.0
06-15PRnewswire
Neurocrine Biosciences Reveals Clinical Findings on CAH Treatment
  • Clinical Findings: Neurocrine Biosciences announced results from a retrospective case series involving 15 patients with classic congenital adrenal hyperplasia (CAH) due to 11β-hydroxylase deficiency, demonstrating that treatment with CRENESSITY® (crinecerfont) led to significant reductions in androgen precursors and improved blood pressure, indicating the drug's potential in managing this rare CAH subtype.
  • Hormonal Control Improvement: The study revealed that all patients with elevated baseline androgen levels experienced a decrease in steroid precursor levels to normal ranges after initiating CRENESSITY, with adult patients also showing improved blood pressure, underscoring the drug's efficacy in enhancing hormonal control.
  • Clinical Significance: This case series provides critical clinical insights for managing patients with 11β-hydroxylase deficiency, aiding clinicians in treatment decisions amidst limited data, thus addressing a complex subgroup within classic CAH.
  • Future Research Directions: Neurocrine emphasized its commitment to further exploring the application of CRENESSITY in classic CAH subtypes, reinforcing its dedication to advancing treatment options for patients with rare endocrine disorders.
Newsfilter
9.0
06-15Newsfilter
CRENESSITY Shows Significant Clinical Effects in Patients with 11β-Hydroxylase Deficiency
  • Significant Efficacy: In patients with 11β-hydroxylase deficiency, CRENESSITY treatment resulted in over 90% median reductions in 11-deoxycortisol and 11-deoxycorticosterone, demonstrating the drug's strong potential in hormone level control.
  • Improved Medication Adherence: Among the 15 patients treated with CRENESSITY, 14 were able to reduce their total glucocorticoid dose, indicating the drug's effectiveness in reducing hormone dependency.
  • Blood Pressure Improvement: Among patients receiving antihypertensive treatment, two were able to reduce or discontinue these medications, suggesting CRENESSITY's potential benefits in managing hypertension.
  • Clinical Research Breakthrough: This retrospective case series provides initial clinical insights for patients with 11β-hydroxylase deficiency, highlighting the importance of CRENESSITY in treating classic congenital adrenal hyperplasia and promoting further research into this rare subtype.
Newsfilter
9.0
06-15Newsfilter
Long-Term Efficacy of VYKAT XR in Treating Prader-Willi Syndrome
  • Significant Treatment Effects: Participants who resumed VYKAT XR after a 16-week randomized withdrawal period demonstrated marked improvements in hyperphagia and behavioral symptoms as early as Week 13, with benefits sustained over two years, indicating the drug's long-term efficacy in Prader-Willi syndrome (PWS) patients.
  • Clinical Trial Data Support: Three-year data for VYKAT XR showed statistically significant improvements in hyperphagia scores compared to controls from the natural history study, with treatment differences of 6.2, 6.5, and 6.2 points at Year 1, Year 2, and Year 3, respectively, highlighting the drug's sustained effectiveness.
  • Comprehensive Behavioral Improvements: Participants who resumed VYKAT XR exhibited significant improvements across all six behavioral domains of PWS over two years, particularly in anxiety, compulsivity, and aggression, further validating the multidimensional efficacy of the drug.
  • Ongoing Safety Monitoring: Throughout the clinical trials, long-term use of VYKAT XR did not result in severe adverse reactions, and participants' body mass index (BMI) remained relatively stable, demonstrating the drug's ability to effectively manage overall health while treating hyperphagia.
NASDAQ.COM
9.0
06-15NASDAQ.COM
Neurocrine Reports Positive Two-Year Data for Crenessity in Pediatric CAH Study
  • Clinical Trial Results: Neurocrine Biosciences reported positive two-year data from its CAHtalyst Pediatric study of Crenessity, indicating slowed bone age progression and improved predicted adult height in treated children and adolescents, demonstrating the drug's efficacy in managing classic congenital adrenal hyperplasia (CAH).
  • Bone Age and Height Improvement: Among 41 growing patients, 24 with advanced bone age at baseline showed stable or improved bone age scores after 24 months, with a mean decrease of 1.12 standard deviations, while nine patients had reductions greater than two standard deviations, alongside a mean increase of 4.7 cm in predicted adult height, highlighting Crenessity's significant impact.
  • Hormonal Control and Drug Use: The findings suggest that sustained hormonal control and reduced glucocorticoid use enabled by Crenessity may support improved growth outcomes in childhood and adolescence, emphasizing the drug's potential advantages in treatment.
  • Positive Market Reaction: Following the announcement, NBIX shares rose over 1% in pre-market trading, closing at $159.76, reflecting market optimism regarding the positive clinical data and potentially driving future growth prospects for the company.
Wall Street analysts forecast NBIX stock price to rise
20 Analyst Rating
Wall Street analysts forecast NBIX stock price to rise
17 Buy
3 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
143.00
Averages
179.68
High
203.00
Current: 0.000
sliders
Low
143.00
Averages
179.68
High
203.00
Goldman Sachs
NULL
to
Buy
initiated
$213
AI Analysis
2026-06-02
Reason
Goldman Sachs
Price Target
$213
AI Analysis
2026-06-02
initiated
NULL
to
Buy
Reason
Goldman Sachs reinstated coverage of Neurocrine with a Buy rating and $213 price target. The completion of the Soleno Therapeutics acquisition bolsters the company's medium-term revenue growth trajectory, the analyst tells investors in a research note. The firm says the deal brings in a third commercial product, Vykat XR, approved for the treatment of Prader-Willi syndrome.
RBC Capital
Outperform
maintain
$180 -> $183
2026-05-29
Reason
RBC Capital
Price Target
$180 -> $183
2026-05-29
maintain
Outperform
Reason
RBC Capital raised the firm's price target on Neurocrine to $183 from $180 and keeps an Outperform rating on the shares. Shares have rebounded following a strong Q1, though the firm believes there are still some concerns Crenessity uptake will hit a near-term ceiling, the analyst tells investors in a research note. RBC adds that its endocrinologist survey suggests there is still considerable room for both near- and long-term growth, with substantial expected expansion in utilization even among docs not currently using the drug.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for NBIX
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Valuation Metrics

The current forward P/E ratio for Neurocrine Biosciences, Inc (NBIX.O) is 22.42, compared to its 5-year average forward P/E of 20.94. For a more detailed relative valuation and DCF analysis to assess Neurocrine Biosciences, Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
20.94
Current PE
22.42
Overvalued PE
24.70
Undervalued PE
17.19

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
20.21
Current EV/EBITDA
15.22
Overvalued EV/EBITDA
25.45
Undervalued EV/EBITDA
14.97

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.31
Current PS
3.55
Overvalued PS
6.35
Undervalued PS
4.26

Financials

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Frequently Asked Questions

What is Neurocrine Biosciences, Inc (NBIX) stock price today?

The current price of NBIX is 158.29 USD — it has decreased -0.45

What is Neurocrine Biosciences, Inc (NBIX)'s business?

Neurocrine Biosciences, Inc. is a neuroscience-focused, biopharmaceutical company. It is engaged in discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. Its diverse portfolio includes the United States Food and Drug Administration-approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, endometriosis and uterine fibroids, as well as a robust pipeline, including multiple compounds in mid-to late-phase clinical development across its core therapeutic areas. Its first-in-class commercial portfolio includes INGREZZA (valbenazine) and CRENESSITY (crinecerfont). It also offers VYKAT XR (diazoxide choline) extended-release tablets, for the treatment of hyperphagia in adults and pediatric patients four years of age and older with Prader-Willi syndrome (PWS). Its pipeline includes direclidine / (M4 Agonist), osavampator॥ / (AMPA PAM) and others.

What is the price predicton of NBIX Stock?

Wall Street analysts forecast NBIX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NBIX is179.68 USD with a low forecast of 143.00 USD and a high forecast of 203.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Neurocrine Biosciences, Inc (NBIX)'s revenue for the last quarter?

Neurocrine Biosciences, Inc revenue for the last quarter amounts to 814.50M USD, increased 42.25

What is Neurocrine Biosciences, Inc (NBIX)'s earnings per share (EPS) for the last quarter?

Neurocrine Biosciences, Inc. EPS for the last quarter amounts to 1.91 USD, increased 2287.50

How many employees does Neurocrine Biosciences, Inc (NBIX). have?

Neurocrine Biosciences, Inc (NBIX) has 2000 emplpoyees as of June 20 2026.

What is Neurocrine Biosciences, Inc (NBIX) market cap?

Today NBIX has the market capitalization of 15.92B USD.