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NBIX Overview

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ET
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At close
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ET
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Intellectia

Loading chart...

High
159.080
Open
156.710
VWAP
157.60
Vol
1.91M
Mkt Cap
15.92B
Low
155.430
Amount
300.69M
EV/EBITDA(TTM)
17.39
Total Shares
100.55M
EV
14.41B
EV/OCF(TTM)
16.68
P/S(TTM)
5.18
Neurocrine Biosciences, Inc. is a neuroscience-focused, biopharmaceutical company. It is engaged in discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. Its diverse portfolio includes the United States Food and Drug Administration-approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, endometriosis and uterine fibroids, as well as a robust pipeline, including multiple compounds in mid-to late-phase clinical development across its core therapeutic areas. Its first-in-class commercial portfolio includes INGREZZA (valbenazine) and CRENESSITY (crinecerfont). It also offers VYKAT XR (diazoxide choline) extended-release tablets, for the treatment of hyperphagia in adults and pediatric patients four years of age and older with Prader-Willi syndrome (PWS). Its pipeline includes direclidine / (M4 Agonist), osavampator॥ / (AMPA PAM) and others.
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Events Timeline

(ET)
2026-05-18
16:10:00
Neurocrine Presents New Data on Mild Tardive Dyskinesia
select
2026-05-18
08:50:00
Neurocrine Completes Acquisition of Soleno
select
2026-05-07 (ET)
2026-05-07
12:00:00
Neurocrine Biosciences Granted FDA Orphan Designation
select
link

News

NASDAQ.COM
8.5
05-19NASDAQ.COM
Neurocrine Presents INGREZZA Data and Completes Soleno Acquisition
  • Clinical Data Presentation: At the American Psychiatric Association 2026 meeting, Neurocrine presented data showing that 96% of patients with mild tardive dyskinesia experienced improvement in uncontrolled movements after starting INGREZZA, with 86% improving within four weeks, indicating significant efficacy in enhancing patient quality of life.
  • Functional Status Improvement: Among 315 patients treated with INGREZZA, 96% of the 81 patients with impacted functional status reported overall improvement, and 83% achieved greater independence, highlighting the drug's critical role in restoring daily living capabilities.
  • Acquisition Completion: Neurocrine announced the completion of its $2.9 billion acquisition of Soleno Therapeutics, which will strengthen its position in endocrinology and rare diseases, adding the FDA-approved VYKAT XR to its portfolio and expanding treatment options.
  • Market Performance: Neurocrine's stock has traded between $117.59 and $162.39 over the past year, closing at $157.21, down 0.76%, but rising 0.50% in after-hours trading, reflecting positive market sentiment towards its new data and acquisition.
PRnewswire
9.0
05-18PRnewswire
Neurocrine Presents New Data on INGREZZA for Mild Tardive Dyskinesia
  • Clinical Data Presentation: At the 2026 American Psychiatric Association Annual Meeting, Neurocrine revealed that 96% of patients with mild tardive dyskinesia treated with INGREZZA reported improvements in movement control, with 86% showing effects within four weeks, demonstrating the drug's efficacy and rapid response in real-world settings.
  • Significant Functional Improvements: The survey results indicated that treated patients experienced notable enhancements across various daily life domains, with 90% reporting functional status impairment and 84% independence impairment, underscoring the impact of mild TD on quality of life.
  • Support for Clinical Guidelines: This analysis supports the American Psychiatric Association's clinical guidelines recommending the consideration of VMAT2 inhibitors for mild TD patients, further solidifying INGREZZA's potential in improving patient functionality and quality of life.
  • Rich Research Background: The analysis was based on clinical data from 315 patients, highlighting the importance of INGREZZA in treating mild TD and showcasing Neurocrine's ongoing commitment to research and innovation in the field of neuropsychiatric disorders.
Newsfilter
9.0
05-18Newsfilter
INGREZZA Shows Significant Efficacy in Mild Tardive Dyskinesia Treatment
  • Clinical Improvement: Among patients with mild tardive dyskinesia treated with INGREZZA, 96% reported improvement in movement control, with 86% showing effects within four weeks, highlighting the drug's rapid efficacy and clinical applicability.
  • Functional Status Enhancement: Following treatment, 96% of 81 patients with impaired functional status experienced improvements, indicating that INGREZZA not only alleviates movement symptoms but also significantly enhances patients' daily living capabilities.
  • Increased Independence: Among treated patients, 83% achieved improved independence, with 70% of those employed or in school reporting enhanced ability to work or attend classes, reflecting the positive impact of treatment on quality of life.
  • Guideline Support: These findings support the American Psychiatric Association's clinical guidelines, emphasizing the necessity of using VMAT2 inhibitors for patients with mild tardive dyskinesia, further solidifying INGREZZA's therapeutic position in this area.
PRnewswire
8.5
05-18PRnewswire
Neurocrine Completes Acquisition of Soleno, Strengthening Leadership in Endocrinology
  • Acquisition Completed: Neurocrine Biosciences finalized its acquisition of Soleno Therapeutics on May 18, 2026, with a total equity value of $2.9 billion, further solidifying its leadership in endocrinology and rare diseases.
  • Portfolio Expansion: The acquisition adds VYKAT™ XR (diazoxide choline) tablets to Neurocrine's portfolio, the first approved treatment for hyperphagia in patients with Prader-Willi syndrome, which is expected to significantly enhance patient quality of life.
  • Significant Market Potential: With approximately 10,000 patients affected by Prader-Willi syndrome in the U.S., characterized by chronic hunger and related behavioral issues, the launch of VYKAT XR addresses a substantial unmet medical need, potentially generating considerable market revenue.
  • Strategic Integration Plans: Neurocrine aims to leverage collaboration with the Soleno team to promote VYKAT XR's market accessibility and treatment efficacy, thereby enhancing the company's competitive edge in the biopharmaceutical industry.
seekingalpha
9.0
05-07seekingalpha
FDA Grants Orphan Drug Designation to Neurocrine's NBIB-223
  • Orphan Drug Status: The FDA has granted orphan drug designation to Neurocrine Biosciences' NBIB-223 (frataxin), which allows for up to seven years of market exclusivity post-approval, significantly enhancing its commercial potential.
  • Tax Incentives: With orphan drug status, NBIB-223 will benefit from tax credits for clinical trial expenses, reducing R&D costs and thereby strengthening Neurocrine's competitive position in the Friedreich ataxia treatment landscape.
  • Gene Therapy Innovation: NBIB-223 is a gene therapy that employs Voyager Therapeutics' modified AAV capsid to deliver the frataxin gene throughout the body, showcasing Neurocrine's commitment to cutting-edge medical technology and innovation.
  • Market Competition: The only approved treatment for Friedreich ataxia is Biogen's Skyclarys (omaveloxolone), and the introduction of NBIB-223 will provide patients with more options while potentially challenging Biogen's market share.
PRnewswire
7.0
05-06PRnewswire
First Expert Recommendations for Glucocorticoid Dose Reduction Published
  • Expert Recommendations Released: Neurocrine Biosciences has published the first expert recommendations for glucocorticoid dose reduction in patients with classic congenital adrenal hyperplasia, marking a significant advancement in the field.
  • Expansion of CRENESSITY® Use: As the real-world application of CRENESSITY® (crinecerfont) expands among pediatric and adult patients, these recommendations address a critical gap in clinical practice, meeting urgent patient needs.
  • Peer-Reviewed Recognition: The guidelines have been published in The Journal of Clinical Endocrinology & Metabolism, indicating rigorous peer review and enhancing their authority and credibility within the medical community.
  • Far-Reaching Clinical Impact: By providing systematic dose reduction recommendations, the guidelines are expected to improve treatment outcomes, reduce the risk of side effects, and ultimately enhance patient quality of life and treatment satisfaction.
Wall Street analysts forecast NBIX stock price to rise
20 Analyst Rating
Wall Street analysts forecast NBIX stock price to rise
17 Buy
3 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
143.00
Averages
179.68
High
203.00
Current: 0.000
sliders
Low
143.00
Averages
179.68
High
203.00
RBC Capital
Outperform
maintain
$180 -> $183
AI Analysis
2026-05-29
New
Reason
RBC Capital
Price Target
$180 -> $183
AI Analysis
2026-05-29
New
maintain
Outperform
Reason
RBC Capital raised the firm's price target on Neurocrine to $183 from $180 and keeps an Outperform rating on the shares. Shares have rebounded following a strong Q1, though the firm believes there are still some concerns Crenessity uptake will hit a near-term ceiling, the analyst tells investors in a research note. RBC adds that its endocrinologist survey suggests there is still considerable room for both near- and long-term growth, with substantial expected expansion in utilization even among docs not currently using the drug.
JPMorgan
Anupam Rama
maintain
$177 -> $185
2026-05-08
Reason
JPMorgan
Anupam Rama
Price Target
$177 -> $185
2026-05-08
maintain
Reason
JPMorgan analyst Anupam Rama raised the firm's price target on Neurocrine to $185 from $177 and keeps an Overweight rating on the shares.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for NBIX
Unlock Now

Valuation Metrics

The current forward P/E ratio for Neurocrine Biosciences, Inc (NBIX.O) is 22.12, compared to its 5-year average forward P/E of 21.01. For a more detailed relative valuation and DCF analysis to assess Neurocrine Biosciences, Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
21.01
Current PE
22.12
Overvalued PE
24.85
Undervalued PE
17.17

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
20.30
Current EV/EBITDA
14.90
Overvalued EV/EBITDA
25.52
Undervalued EV/EBITDA
15.07

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
5.35
Current PS
3.47
Overvalued PS
6.40
Undervalued PS
4.30

Financials

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NBIX
+36.43%
3M Return
I
IEQ Capital, LLC
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+28.45%
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S
Stacey Braun Associates, Inc.
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Cookson Peirce & Co Inc
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Renaissance Technologies Corp.
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Azimuth Capital Investment Management LLC
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Frequently Asked Questions

What is Neurocrine Biosciences, Inc (NBIX) stock price today?

The current price of NBIX is 158.3 USD — it has increased 1.22

What is Neurocrine Biosciences, Inc (NBIX)'s business?

Neurocrine Biosciences, Inc. is a neuroscience-focused, biopharmaceutical company. It is engaged in discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. Its diverse portfolio includes the United States Food and Drug Administration-approved treatments for tardive dyskinesia, chorea associated with Huntington’s disease, endometriosis and uterine fibroids, as well as a robust pipeline, including multiple compounds in mid-to late-phase clinical development across its core therapeutic areas. Its first-in-class commercial portfolio includes INGREZZA (valbenazine) and CRENESSITY (crinecerfont). It also offers VYKAT XR (diazoxide choline) extended-release tablets, for the treatment of hyperphagia in adults and pediatric patients four years of age and older with Prader-Willi syndrome (PWS). Its pipeline includes direclidine / (M4 Agonist), osavampator॥ / (AMPA PAM) and others.

What is the price predicton of NBIX Stock?

Wall Street analysts forecast NBIX stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for NBIX is179.68 USD with a low forecast of 143.00 USD and a high forecast of 203.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Neurocrine Biosciences, Inc (NBIX)'s revenue for the last quarter?

Neurocrine Biosciences, Inc revenue for the last quarter amounts to 814.50M USD, increased 42.25

What is Neurocrine Biosciences, Inc (NBIX)'s earnings per share (EPS) for the last quarter?

Neurocrine Biosciences, Inc. EPS for the last quarter amounts to 1.91 USD, increased 2287.50

How many employees does Neurocrine Biosciences, Inc (NBIX). have?

Neurocrine Biosciences, Inc (NBIX) has 2000 emplpoyees as of May 31 2026.

What is Neurocrine Biosciences, Inc (NBIX) market cap?

Today NBIX has the market capitalization of 15.92B USD.