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IMNM Overview

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$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
22.830
Open
22.510
VWAP
22.15
Vol
1.73M
Mkt Cap
2.47B
Low
21.790
Amount
38.28M
EV/EBITDA(TTM)
--
Total Shares
113.25M
EV
1.89B
EV/OCF(TTM)
--
P/S(TTM)
520.65
Immunome, Inc. is a clinical-stage targeted oncology company, which is focused on developing first-in-class and targeted therapies designed to improve outcomes for cancer patients. The Company is engaged in advancing an innovative portfolio of therapeutics in the design, development, and commercialization of targeted cancer therapies, including antibody-drug conjugate therapies (ADCs). Its advanced pipeline programs are varegacestat, a gamma secretase inhibitor which is in a Phase III trial for the treatment of desmoid tumors; IM-1021, an ROR1-targeted ADC which is in a Phase I trial, and IM-3050, a FAP-targeted radioligand. The Company's pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 is a potential first-in-class ADC that targets an undisclosed receptor that is expressed in a range of solid tumors, including colorectal cancer and ovarian cancers.
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Events Timeline

(ET)
2026-05-31
09:20:00
Immunome Announces Phase 3 Trial Results for Varegacestat
select
2026-05-12 (ET)
2026-05-12
16:10:00
Immunome Submits NDA Application for Varegacestat
select
2026-04-29 (ET)
2026-04-29
07:40:00
Immunome Submits NDA for Varegacestat to FDA
select
2026-04-07 (ET)
2026-04-07
13:30:00
Gilead to Acquire Tubulis for $3.15B
select

News

seekingalpha
9.5
05-12seekingalpha
Immunome Q1 Earnings Beat Expectations
  • Earnings Surprise: Immunome reported a Q1 GAAP EPS of -$0.48, beating expectations by $0.09, indicating an improvement in financial performance that could bolster investor confidence.
  • Strong Cash Position: As of March 31, 2026, Immunome's cash and cash equivalents totaled $582.7 million, which is expected to fund operations into 2028, ensuring continuity in research and operational activities.
  • Optimistic Future Outlook: The company anticipates an upcoming New Drug Application (NDA) that could drive future revenue growth, enhancing market expectations for its valuation and potentially attracting more investor interest.
  • Investment Case Analysis: Seeking Alpha's quantitative rating on Immunome reflects positive market sentiment, and combined with historical financial data, underscores the company's potential and investment value in the biopharmaceutical sector.
Newsfilter
8.5
04-29Newsfilter
Immunome Submits NDA for Varegacestat Supported by Positive Phase 3 RINGSIDE Results
  • Clinical Trial Success: Immunome's Phase 3 RINGSIDE trial demonstrated a significant improvement in progression-free survival for varegacestat compared to placebo, with a hazard ratio of 0.16 (p<0.0001), providing robust data support for the New Drug Application and potentially transforming treatment options for adult patients.
  • Significant Efficacy: The trial achieved a confirmed objective response rate of 56%, markedly higher than the 9% in the placebo group (p<0.0001), indicating that varegacestat has substantial clinical significance in treating progressing desmoid tumors, which may enhance patients' quality of life.
  • Good Safety Profile: Although 82% of participants experienced adverse events like diarrhea, most were grade 1 or 2, indicating that varegacestat has a favorable safety and tolerability profile, making it an attractive treatment option.
  • Future Outlook: Immunome plans to present detailed RINGSIDE data at the 2026 ASCO Annual Meeting, which could further elevate market interest in varegacestat and potentially drive its application in cancer treatment.
Fool
5.0
04-05Fool
Immunome CSO Sells Shares Under 10b5-1 Plan
  • Transaction Overview: Immunome's Chief Scientific Officer Jack Higgins sold 9,438 shares of common stock on April 2, 2026, for a total value of $204,238.32, indicating a strategic approach to liquidity management.
  • Ownership Changes: This sale reduced Higgins's direct holdings by 30.02%, from 31,438 to 22,000 shares, while his indirect holdings remained unchanged, reflecting his continued confidence in the company's future.
  • Transaction Context: The sale was executed under a pre-arranged 10b5-1 trading plan established in December 2025, suggesting it was a routine liquidity management action rather than a market-timing decision, highlighting Higgins's financial diversification strategy.
  • Company Outlook: Immunome is advancing its antibody therapeutic programs, particularly IMM-ONC-01 for cancer and IMM-BCP-01 for SARS-CoV-2, with a New Drug Application submission planned for Q2 2026, showcasing the company's strong growth potential in the biotechnology sector.
NASDAQ.COM
5.0
04-05NASDAQ.COM
Immunome Executive Share Sale Details
  • Share Sale Overview: Jack Higgins, Chief Scientific Officer of Immunome, sold 9,438 shares of common stock on April 2, 2026, for approximately $204,000, representing 30.02% of his holdings, highlighting his focus on financial diversification.
  • Holding Changes: Post-sale, Higgins holds 22,000 shares directly and 3,000 shares indirectly, with a direct holding valued at roughly $480,000, indicating substantial ongoing investment in the company.
  • Trading Plan Context: The sale was executed under a pre-established 10b5-1 trading plan set up in December 2025, locking in the timing and price, which suggests a strategic financial decision rather than a reaction to market conditions.
  • Company Growth Prospects: Immunome is advancing its ADC-heavy pipeline, particularly with varegacestat's Phase 3 RINGSIDE trial hitting its primary endpoint in December 2025, with an NDA submission planned for Q2 2026, showcasing the company's potential in antibody therapeutics.
Yahoo Finance
5.0
03-05Yahoo Finance
Immunome Grants Stock Options to New Employees
  • Stock Option Grant: On March 2, 2026, Immunome granted a total of 282,000 non-statutory stock options to seven new employees, aimed at attracting and retaining talent, thereby enhancing the company's competitive position in cancer therapy.
  • Exercise Price Setting: Each stock option has an exercise price of $22.21, equal to the closing price on March 2, 2026, which helps incentivize employees to grow with the company, increasing their sense of belonging and motivation.
  • Vesting Schedule: The stock options will vest over four years, with 25% vesting on the one-year anniversary of the grant and the remainder vesting monthly, ensuring continued employee contributions during their service, thus enhancing team stability.
  • Incentive Plan Compliance: The stock option grant complies with Nasdaq Listing Rule 5635(c)(4), indicating the company's commitment to compliance and transparency in talent acquisition and incentives, which helps boost investor confidence.
Fool
8.5
03-04Fool
Opaleye Management Sells Entire Stake in Immunome for $37.3 Million
  • Stake Sale Overview: Opaleye Management sold its entire 3,185,000 shares of Immunome in Q4 2025 for an estimated $37.3 million, resulting in a complete exit from the position and a corresponding $37.3 million drop in quarter-end asset value.
  • Portfolio Impact: This transaction reduced Immunome's representation in Opaleye's portfolio from 5.3% to 0%, indicating a total divestment that could influence the fund's future investment strategy.
  • Market Performance Analysis: As of February 17, 2026, Immunome shares were priced at $22.69, reflecting a 128.5% increase over the past year, yet a 9% decline over the last two years, highlighting the stock's volatility that may affect investor confidence.
  • Investor Strategy Recommendation: Given the volatility of biotech stocks, retail investors are advised to consider biotech ETFs to spread risk, allowing them to benefit from long-term industry growth while mitigating portfolio volatility.
Wall Street analysts forecast IMNM stock price to rise
11 Analyst Rating
Wall Street analysts forecast IMNM stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
21.00
Averages
33.20
High
40.00
Current: 0.000
sliders
Low
21.00
Averages
33.20
High
40.00
Truist
Buy
maintain
$36 -> $37
AI Analysis
2026-05-28
New
Reason
Truist
Price Target
$36 -> $37
AI Analysis
2026-05-28
New
maintain
Buy
Reason
Truist raised the firm's price target on Immunome to $37 from $36 and keeps a Buy rating on the shares. The firm is positive on the potential of varegacestat's to penetrate and expand the desmoid tumor market, supported by what it sees as a best-in-class Phase 3 efficacy and safety profile as well as convenient once-daily oral dosing, the analyst tells investors in a research note. Immunome's seasoned ex-Seagen leadership team is also well positioned to replicate prior success through next-wave ADC programs featuring novel Top1i payload/linker technology targeting ROR1 and beyond, the firm added.
Barclays
Lukas Shumway
Overweight
initiated
$36
2026-05-28
New
Reason
Barclays
Lukas Shumway
Price Target
$36
2026-05-28
New
initiated
Overweight
Reason
Barclays analyst Lukas Shumway initiated coverage of Immunome with an Overweight rating and $36 price target. Immunome is a biopharmaceutical company focused primarily on the development of antibody-drug conjugate therapeutics to treat various cancers, the analyst tells investors in a research note. The firm says the company is on the verge of potentially launching its first commercial product, varegacestat, in desmoid tumors within the next 12 months pending a positive regulatory decision. It views the upcoming IM-1021 data in non-Hodgkin lymphoma as a \"de-risking event for the platform.\"
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Valuation Metrics

The current forward P/E ratio for Immunome Inc (IMNM.O) is 0.00, compared to its 5-year average forward P/E of -4.94. For a more detailed relative valuation and DCF analysis to assess Immunome Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-4.94
Current PE
0.00
Overvalued PE
-2.47
Undervalued PE
-7.41

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.08
Current EV/EBITDA
-0.41
Overvalued EV/EBITDA
0.77
Undervalued EV/EBITDA
-2.93

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
154.32
Current PS
30.68
Overvalued PS
472.67
Undervalued PS
-164.02

Financials

AI Analysis
Annual
Quarterly

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Whales Holding IMNM

R
Redmile Group, LLC
Holding
IMNM
+7.59%
3M Return
E
EcoR1 Capital, LLC
Holding
IMNM
+5.17%
3M Return
S
Sofinnova Investment, Inc.
Holding
IMNM
+5.14%
3M Return
J
Jefferies Financial Group Inc.
Holding
IMNM
+5.06%
3M Return

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Frequently Asked Questions

What is Immunome Inc (IMNM) stock price today?

The current price of IMNM is 21.83 USD — it has decreased -3.15

What is Immunome Inc (IMNM)'s business?

Immunome, Inc. is a clinical-stage targeted oncology company, which is focused on developing first-in-class and targeted therapies designed to improve outcomes for cancer patients. The Company is engaged in advancing an innovative portfolio of therapeutics in the design, development, and commercialization of targeted cancer therapies, including antibody-drug conjugate therapies (ADCs). Its advanced pipeline programs are varegacestat, a gamma secretase inhibitor which is in a Phase III trial for the treatment of desmoid tumors; IM-1021, an ROR1-targeted ADC which is in a Phase I trial, and IM-3050, a FAP-targeted radioligand. The Company's pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 is a potential first-in-class ADC that targets an undisclosed receptor that is expressed in a range of solid tumors, including colorectal cancer and ovarian cancers.

What is the price predicton of IMNM Stock?

Wall Street analysts forecast IMNM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IMNM is33.20 USD with a low forecast of 21.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Immunome Inc (IMNM)'s revenue for the last quarter?

Immunome Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Immunome Inc (IMNM)'s earnings per share (EPS) for the last quarter?

Immunome Inc. EPS for the last quarter amounts to -0.48 USD, decreased -7.69

How many employees does Immunome Inc (IMNM). have?

Immunome Inc (IMNM) has 117 emplpoyees as of May 31 2026.

What is Immunome Inc (IMNM) market cap?

Today IMNM has the market capitalization of 2.47B USD.