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IMNM Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
24.810
Open
23.850
VWAP
24.32
Vol
1.02M
Mkt Cap
2.79B
Low
23.530
Amount
24.87M
EV/EBITDA(TTM)
--
Total Shares
113.13M
EV
2.13B
EV/OCF(TTM)
--
P/S(TTM)
309.88
Immunome, Inc. is a clinical-stage targeted oncology company, which is focused on developing first-in-class and targeted therapies designed to improve outcomes for cancer patients. The Company is engaged in advancing an innovative portfolio of therapeutics in the design, development, and commercialization of targeted cancer therapies, including antibody-drug conjugate therapies (ADCs). Its advanced pipeline programs are varegacestat, a gamma secretase inhibitor which is in a Phase III trial for the treatment of desmoid tumors; IM-1021, an ROR1-targeted ADC which is in a Phase I trial, and IM-3050, a FAP-targeted radioligand. The Company's pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 is a potential first-in-class ADC that targets an undisclosed receptor that is expressed in a range of solid tumors, including colorectal cancer and ovarian cancers.
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Events Timeline

(ET)
2026-04-07
13:30:00
Gilead to Acquire Tubulis for $3.15B
select
2026-03-03 (ET)
2026-03-03
16:10:00
Immunome Cash and Cash Equivalents Reach $653.5 Million
select
2025-12-17 (ET)
2025-12-17
16:20:00
Major Averages Close Broadly Lower as Fed Policy Concerns Persist
select
2025-12-17
12:10:00
Major US Averages Broadly Lower as Oil Prices Rise
select

News

Fool
5.0
04-05Fool
Immunome CSO Sells Shares Under 10b5-1 Plan
  • Transaction Overview: Immunome's Chief Scientific Officer Jack Higgins sold 9,438 shares of common stock on April 2, 2026, for a total value of $204,238.32, indicating a strategic approach to liquidity management.
  • Ownership Changes: This sale reduced Higgins's direct holdings by 30.02%, from 31,438 to 22,000 shares, while his indirect holdings remained unchanged, reflecting his continued confidence in the company's future.
  • Transaction Context: The sale was executed under a pre-arranged 10b5-1 trading plan established in December 2025, suggesting it was a routine liquidity management action rather than a market-timing decision, highlighting Higgins's financial diversification strategy.
  • Company Outlook: Immunome is advancing its antibody therapeutic programs, particularly IMM-ONC-01 for cancer and IMM-BCP-01 for SARS-CoV-2, with a New Drug Application submission planned for Q2 2026, showcasing the company's strong growth potential in the biotechnology sector.
NASDAQ.COM
5.0
04-05NASDAQ.COM
Immunome Executive Share Sale Details
  • Share Sale Overview: Jack Higgins, Chief Scientific Officer of Immunome, sold 9,438 shares of common stock on April 2, 2026, for approximately $204,000, representing 30.02% of his holdings, highlighting his focus on financial diversification.
  • Holding Changes: Post-sale, Higgins holds 22,000 shares directly and 3,000 shares indirectly, with a direct holding valued at roughly $480,000, indicating substantial ongoing investment in the company.
  • Trading Plan Context: The sale was executed under a pre-established 10b5-1 trading plan set up in December 2025, locking in the timing and price, which suggests a strategic financial decision rather than a reaction to market conditions.
  • Company Growth Prospects: Immunome is advancing its ADC-heavy pipeline, particularly with varegacestat's Phase 3 RINGSIDE trial hitting its primary endpoint in December 2025, with an NDA submission planned for Q2 2026, showcasing the company's potential in antibody therapeutics.
Yahoo Finance
5.0
03-05Yahoo Finance
Immunome Grants Stock Options to New Employees
  • Stock Option Grant: On March 2, 2026, Immunome granted a total of 282,000 non-statutory stock options to seven new employees, aimed at attracting and retaining talent, thereby enhancing the company's competitive position in cancer therapy.
  • Exercise Price Setting: Each stock option has an exercise price of $22.21, equal to the closing price on March 2, 2026, which helps incentivize employees to grow with the company, increasing their sense of belonging and motivation.
  • Vesting Schedule: The stock options will vest over four years, with 25% vesting on the one-year anniversary of the grant and the remainder vesting monthly, ensuring continued employee contributions during their service, thus enhancing team stability.
  • Incentive Plan Compliance: The stock option grant complies with Nasdaq Listing Rule 5635(c)(4), indicating the company's commitment to compliance and transparency in talent acquisition and incentives, which helps boost investor confidence.
Fool
8.5
03-04Fool
Opaleye Management Sells Entire Stake in Immunome for $37.3 Million
  • Stake Sale Overview: Opaleye Management sold its entire 3,185,000 shares of Immunome in Q4 2025 for an estimated $37.3 million, resulting in a complete exit from the position and a corresponding $37.3 million drop in quarter-end asset value.
  • Portfolio Impact: This transaction reduced Immunome's representation in Opaleye's portfolio from 5.3% to 0%, indicating a total divestment that could influence the fund's future investment strategy.
  • Market Performance Analysis: As of February 17, 2026, Immunome shares were priced at $22.69, reflecting a 128.5% increase over the past year, yet a 9% decline over the last two years, highlighting the stock's volatility that may affect investor confidence.
  • Investor Strategy Recommendation: Given the volatility of biotech stocks, retail investors are advised to consider biotech ETFs to spread risk, allowing them to benefit from long-term industry growth while mitigating portfolio volatility.
NASDAQ.COM
8.5
03-04NASDAQ.COM
Opaleye Management Exits Entire Stake in Immunome
  • Complete Exit: Opaleye Management sold all 3,185,000 shares of Immunome in Q4 2025 for an estimated $37.30 million, reflecting a full exit that resulted in a 4.92% decrease in its assets under management (AUM).
  • Portfolio Shift: The sale eliminated Immunome's representation in Opaleye's portfolio, which previously accounted for 5.3% of AUM, indicating a significant strategic shift that may influence future investment decisions.
  • Stock Volatility Impact: While Immunome's stock surged 128.5% over the past year, it has declined approximately 9% over the last two years, highlighting the stock's volatility and prompting Opaleye to reassess its investment strategy.
  • Market Outlook: Despite Immunome's strong performance in the past year, analysts recommend that investors consider more stable biotech ETFs to mitigate risk, reflecting a cautious market sentiment towards individual biotech stocks.
seekingalpha
8.5
03-03seekingalpha
Immunome Reports FY Loss and Declining Revenue Amid Public Offering
  • Disappointing Earnings: Immunome's reported GAAP EPS of -$2.43 misses expectations by $0.16, indicating challenges in profitability that could undermine investor confidence and affect stock performance.
  • Declining Collaboration Revenue: The company reported collaboration revenue of $6.9 million, a 23.7% year-over-year decline, falling short of the expected $7.7 million, which may negatively impact future liquidity and operational funding.
  • Maintaining Strong Buy Rating: Despite the disappointing earnings, Immunome continues to maintain a 'Strong Buy' rating on the successful RINGSIDE trial with Varegacestat, reflecting confidence in its R&D pipeline that may attract long-term investors.
  • Proposed Public Offering: Immunome has announced a proposed public offering aimed at raising funds to support its R&D projects, which may exert short-term pressure on the stock price but is expected to enhance financial stability in the long run.
Wall Street analysts forecast IMNM stock price to rise
11 Analyst Rating
Wall Street analysts forecast IMNM stock price to rise
11 Buy
0 Hold
0 Sell
Strong Buy
Current: 0.000
sliders
Low
21.00
Averages
33.20
High
40.00
Current: 0.000
sliders
Low
21.00
Averages
33.20
High
40.00
Lake Street
Chad Messer
Buy
downgrade
$32 -> $30
AI Analysis
2026-03-05
Reason
Lake Street
Chad Messer
Price Target
$32 -> $30
AI Analysis
2026-03-05
downgrade
Buy
Reason
Lake Street analyst Chad Messer lowered the firm's price target on Immunome to $30 from $32 and keeps a Buy rating on the shares. Strategic execution remains on track, while a "significantly bolstered balance sheet" extends the company's projected cash runway into 2028, the analyst tells investors in a Q4 recap.
Craig-Hallum
Adam Vogel
Buy
maintain
$33 -> $36
2026-03-04
Reason
Craig-Hallum
Adam Vogel
Price Target
$33 -> $36
2026-03-04
maintain
Buy
Reason
Craig-Hallum analyst Adam Vogel raised the firm's price target on Immunome to $36 from $33 and keeps a Buy rating on the shares. The firm notes Immunome reported FY25 results and provided an update that reinforces the transition of the story from binary clinical risk to commercial execution, with a Q2 NDA planned for varegacestat, runway into 2028, and multiple ADC catalysts ahead. With the balance sheet now strengthened, Craig-Hallum views downside as increasingly protected, while upside is tied to differentiation in desmoid and platform validation in 2026.
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Valuation Metrics

The current forward P/E ratio for Immunome Inc (IMNM.O) is 0.00, compared to its 5-year average forward P/E of -5.15. For a more detailed relative valuation and DCF analysis to assess Immunome Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PE
-5.15
Current PE
0.00
Overvalued PE
-2.36
Undervalued PE
-7.94

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average EV/EBITDA
-1.06
Current EV/EBITDA
-0.78
Overvalued EV/EBITDA
0.79
Undervalued EV/EBITDA
-2.91

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
N/A
5Y Average PS
153.36
Current PS
32.01
Overvalued PS
471.82
Undervalued PS
-165.10

Financials

AI Analysis
Annual
Quarterly

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Whales Holding IMNM

E
EcoR1 Capital, LLC
Holding
IMNM
+12.59%
3M Return
S
Sofinnova Investment, Inc.
Holding
IMNM
+9.18%
3M Return
S
Scharf Investments, LLC
Holding
IMNM
+3.09%
3M Return

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Frequently Asked Questions

What is Immunome Inc (IMNM) stock price today?

The current price of IMNM is 24.63 USD — it has increased 5.89

What is Immunome Inc (IMNM)'s business?

Immunome, Inc. is a clinical-stage targeted oncology company, which is focused on developing first-in-class and targeted therapies designed to improve outcomes for cancer patients. The Company is engaged in advancing an innovative portfolio of therapeutics in the design, development, and commercialization of targeted cancer therapies, including antibody-drug conjugate therapies (ADCs). Its advanced pipeline programs are varegacestat, a gamma secretase inhibitor which is in a Phase III trial for the treatment of desmoid tumors; IM-1021, an ROR1-targeted ADC which is in a Phase I trial, and IM-3050, a FAP-targeted radioligand. The Company's pipeline also includes IM-1617, IM-1335, and IM-1340, all of which are preclinical ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 is a potential first-in-class ADC that targets an undisclosed receptor that is expressed in a range of solid tumors, including colorectal cancer and ovarian cancers.

What is the price predicton of IMNM Stock?

Wall Street analysts forecast IMNM stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for IMNM is33.20 USD with a low forecast of 21.00 USD and a high forecast of 40.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Immunome Inc (IMNM)'s revenue for the last quarter?

Immunome Inc revenue for the last quarter amounts to 0.00 USD, decreased -100.00

What is Immunome Inc (IMNM)'s earnings per share (EPS) for the last quarter?

Immunome Inc. EPS for the last quarter amounts to -0.74 USD, decreased -42.19

How many employees does Immunome Inc (IMNM). have?

Immunome Inc (IMNM) has 117 emplpoyees as of April 20 2026.

What is Immunome Inc (IMNM) market cap?

Today IMNM has the market capitalization of 2.79B USD.