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HRMY Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
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0.000(0.000%)Aft-market
ET
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Intellectia

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High
34.310
Open
33.670
VWAP
33.97
Vol
467.85K
Mkt Cap
1.98B
Low
33.435
Amount
15.89M
EV/EBITDA(TTM)
5.89
Total Shares
57.89M
EV
1.45B
EV/OCF(TTM)
4.25
P/S(TTM)
2.17
Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.
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Events Timeline

(ET)
2026-05-07
07:40:00
Harmony Biosciences Backs FY26 Revenue View of $1B-$1.04B
select
2026-05-07
07:40:00
Harmony Biosciences Q1 Revenue $215.39M, Below Expectations
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2026-04-21 (ET)
2026-04-21
12:30:00
Mizuho Says Harmony Biosciences Files New Patent Lawsuit
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2026-04-21
12:30:00
Harmony Biosciences Shares Rise to $34.35
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2026-04-21
12:30:00
Harmony Shares Jump 14% to $33.58 After Mizuho Uncovers New Patent Lawsuit
select
2026-04-14 (ET)
2026-04-14
08:30:00
Harmony Reiterates 2026 Net Product Revenue Guidance of $1.0 to $1.04 Billion
select
2026-04-14
08:30:00
Harmony Biosciences Appoints Glenn Reicin as CFO
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News

NASDAQ.COM
5.0
09:04 AMNASDAQ.COM
Avalo Therapeutics Appoints New Board Member
  • New Board Appointment: Avalo Therapeutics has appointed Ron Philips to its Board of Directors, bringing over 30 years of experience in the biopharmaceutical industry, which is expected to significantly impact the company's strategic execution.
  • Extensive Industry Background: Currently serving as executive chair of CREATE Medicines and on the boards of Harmony Biosciences and City Therapeutics, Philips was previously the CEO of Orbital Therapeutics, showcasing his deep expertise in biotechnology.
  • Clinical Trial Advancement: Avalo plans to advance its investigational anti-IL-1ß monoclonal antibody Abdakibart (AVTX-009) into a registrational Phase 3 trial in the first half of 2027, marking a significant step in its drug development efforts.
  • Stock Price Movement: Avalo closed at $17.83 on Tuesday, up 4.39%, but shares fell 1.51% in after-hours trading to $17.56, indicating cautious market sentiment regarding the new appointment.
Newsfilter
8.5
06-11Newsfilter
Paragon Biosciences Closes Sale of Emalex to Teva
  • Significant Transaction Value: Paragon Biosciences successfully sold Emalex Biosciences to Teva Pharmaceuticals for a total of $700 million in cash and up to $200 million in commercial milestone payments, showcasing Paragon's strong capabilities and market recognition in the biotech sector.
  • Innovative Drug Development: Emalex's Ecopipam, a first-in-class treatment for Tourette syndrome, demonstrated significant efficacy in a Phase 3 study published in JAMA Neurology, successfully reducing relapse time and improving tic symptoms, indicating its potential market value.
  • Clinical Progress and Regulatory Path: Currently in clinical development, Ecopipam is expected to submit its New Drug Application in the second half of 2026, and if approved, it will be the first new treatment option for Tourette syndrome in over a decade, addressing urgent medical needs for patients.
  • Company Mission and Vision: Paragon's founder, Jeff Aronin, emphasized that the company's mission is to translate scientific breakthroughs into medicines for patients, and it will continue to focus on unmet medical needs while advancing innovative drug development and market entry.
Fool
6.5
05-19Fool
Bridge City Capital Fully Exits Harmony Biosciences Holdings
  • Complete Exit: Bridge City Capital fully exited its position in Harmony Biosciences Holdings during Q1, selling 237,103 shares for an estimated $7.77 million, indicating a reassessment of the company's future prospects.
  • AUM Reduction: The transaction resulted in an $8.87 million decrease in Bridge City’s quarter-end position value in Harmony, highlighting the significant reduction of the company’s importance in the fund, which previously represented 2.6% of AUM.
  • Poor Market Performance: As of May 12, 2026, Harmony's shares were priced at $30.15, down 15.4% over the past year, underperforming the S&P 500 by 42.07 percentage points, raising concerns about its growth potential.
  • Investor Insight: Bridge City’s exit may reflect a valuation reassessment, prompting investors to monitor Harmony's long-term potential in the rare neurological disorder treatment market amidst changing market dynamics.
NASDAQ.COM
6.5
05-19NASDAQ.COM
Bridge City Capital Fully Exits Harmony Biosciences Holdings
  • Complete Position Exit: Bridge City Capital sold all 237,103 shares of Harmony Biosciences in Q1, with an estimated transaction value of $7.77 million, indicating a significant loss of confidence that resulted in an $8.87 million decrease in the company's position value.
  • AUM Reduction: This transaction led to a 2.15% reduction in Bridge City Capital's 13F reportable assets under management, reflecting a reassessment of their investment strategy, possibly due to concerns over market outlook.
  • Industry Dynamics Impact: Harmony Biosciences focuses on treatments for rare neurological diseases, yet its recent poor market performance may have prompted institutional exits, suggesting a reevaluation of the company's future growth potential, which could affect its stock price and market confidence.
  • Investor Caution: Before investing in Harmony Biosciences, investors should note that the company did not make it onto The Motley Fool Stock Advisor's list of top stocks, indicating a cautious market sentiment regarding its future performance.
seekingalpha
9.5
05-07seekingalpha
Harmony Biosciences Q1 2026 Earnings Call Insights
  • Financial Performance: Harmony Biosciences reported net sales of $215.4 million in Q1 2026, reflecting a 17% year-over-year growth, and despite facing market access challenges, the company maintains its full-year revenue guidance of $1 billion to $1.04 billion, demonstrating confidence in future growth.
  • Intellectual Property Protection: The company has successfully extended its pitolisant patent protection until March 2030 by settling with 6 of the 7 ANDA filers, ensuring market competitiveness and laying a foundation for future business development.
  • R&D Progress: The NDA submission for pitolisant GR is expected this quarter with a target PDUFA date in Q1 2027, indicating ongoing advancements in drug development that could drive future revenue growth.
  • Cash Flow Position: As of the end of Q1, Harmony Biosciences holds $870.5 million in cash and cash equivalents, with plans to deploy these funds into business development aimed at revenue contributions in the 2028 to 2032 timeframe, reflecting a proactive capital management strategy.
seekingalpha
9.5
05-07seekingalpha
Harmony Biosciences Q1 Earnings Miss Expectations
  • Disappointing Earnings: Harmony Biosciences reported a Q1 GAAP EPS of $0.55, missing expectations by $0.14, indicating pressure on profitability that could undermine investor confidence.
  • Lackluster Revenue Growth: The company generated $215.3 million in revenue for Q1, a 16.6% year-over-year increase, yet it fell short of expectations by $5.54 million, suggesting that market demand did not meet anticipated levels, potentially impacting future growth strategies.
  • Rising Expenses: Total operating expenses reached $133.6 million in Q1, up 38% from $96.5 million in the same quarter of 2025, indicating significant cost pressures in operational management that could affect profit margins.
  • Increased Administrative Costs: General and administrative expenses were $32.5 million in Q1, a 4% increase from $31.2 million in the same quarter last year, reflecting ongoing rising expenditures in management and operations that may impact overall financial health.
Wall Street analysts forecast HRMY stock price to rise
6 Analyst Rating
Wall Street analysts forecast HRMY stock price to rise
5 Buy
0 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
Truist
Hold
maintain
$25 -> $29
AI Analysis
2026-05-08
Reason
Truist
Price Target
$25 -> $29
AI Analysis
2026-05-08
maintain
Hold
Reason
Truist raised the firm's price target on Harmony Biosciences to $29 from $25 and keeps a Hold rating on the shares after meeting with the company's management team. Wakix has a reasonable path to achieving FY26 guidance of over $1B, supported in part by the recent 20% expansion of the sales force, the analyst tells investors in a research note.
H.C. Wainwright
Patrick Trucchio
Buy
maintain
$55
2026-04-23
Reason
H.C. Wainwright
Patrick Trucchio
Price Target
$55
2026-04-23
maintain
Buy
Reason
H.C. Wainwright analyst Patrick Trucchio says that following an April 22 meeting with President and CEO Jeff Dayno, newly appointed CFO Glenn Reicin, and Head of Investor Relations Brennan Doyle, the firm has increased conviction that recent Harmony Biosciences weakness related to IP litigation has created an attractive buying opportunity. Wainwright expects a positive outcome from the IP litigation filed this week, which could support the transition of the WAKIX franchise to next-generation formulations. With shares down about 15% year-to-date vs. XBI up 12%, reflecting what the firm views as an excessive IP overhang, Wainwright reiterates a Buy rating and $55 price target on Harmony.
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Valuation Metrics

The current forward P/E ratio for Harmony Biosciences Holdings Inc (HRMY.O) is 10.59, compared to its 5-year average forward P/E of 14.88. For a more detailed relative valuation and DCF analysis to assess Harmony Biosciences Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
14.88
Current PE
10.59
Overvalued PE
20.71
Undervalued PE
9.06

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
9.10
Current EV/EBITDA
6.92
Overvalued EV/EBITDA
13.05
Undervalued EV/EBITDA
5.14

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.51
Current PS
1.68
Overvalued PS
5.14
Undervalued PS
1.88

Financials

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Whales Holding HRMY

C
CX Institutional, LLC
Holding
HRMY
+12.27%
3M Return
T
Tang Capital Management, LLC
Holding
HRMY
+10.56%
3M Return

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Frequently Asked Questions

What is Harmony Biosciences Holdings Inc (HRMY) stock price today?

The current price of HRMY is 34.16 USD — it has increased 2.18

What is Harmony Biosciences Holdings Inc (HRMY)'s business?

Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.

What is the price predicton of HRMY Stock?

Wall Street analysts forecast HRMY stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for HRMY is43.83 USD with a low forecast of 32.00 USD and a high forecast of 55.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Harmony Biosciences Holdings Inc (HRMY)'s revenue for the last quarter?

Harmony Biosciences Holdings Inc revenue for the last quarter amounts to 215.39M USD, increased 16.59

What is Harmony Biosciences Holdings Inc (HRMY)'s earnings per share (EPS) for the last quarter?

Harmony Biosciences Holdings Inc. EPS for the last quarter amounts to 0.55 USD, decreased -29.49

How many employees does Harmony Biosciences Holdings Inc (HRMY). have?

Harmony Biosciences Holdings Inc (HRMY) has 293 emplpoyees as of June 24 2026.

What is Harmony Biosciences Holdings Inc (HRMY) market cap?

Today HRMY has the market capitalization of 1.98B USD.