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HRMY Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
32.125
Open
31.800
VWAP
31.23
Vol
933.30K
Mkt Cap
1.78B
Low
30.770
Amount
29.15M
EV/EBITDA(TTM)
5.32
Total Shares
57.87M
EV
1.25B
EV/OCF(TTM)
3.57
P/S(TTM)
2.16
Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.
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Events Timeline

(ET)
2026-04-21
12:30:00
Mizuho Says Harmony Biosciences Files New Patent Lawsuit
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2026-04-21
12:30:00
Harmony Shares Jump 14% to $33.58 After Mizuho Uncovers New Patent Lawsuit
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2026-04-21
12:30:00
Harmony Biosciences Shares Rise to $34.35
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2026-04-14 (ET)
2026-04-14
08:30:00
Harmony Biosciences Appoints Glenn Reicin as CFO
select
2026-04-14
08:30:00
Harmony Reiterates 2026 Net Product Revenue Guidance of $1.0 to $1.04 Billion
select
2026-04-02 (ET)
2026-04-02
08:20:00
Harmony Biosciences Appoints Peter Anastasiou as COO
select

News

seekingalpha
9.5
04-21seekingalpha
Harmony Biosciences Shares Rise on Patent Litigation News
  • Patent Litigation Update: Harmony Biosciences filed a patent infringement lawsuit on April 20 against AET Pharma and its partner Sandoz regarding the '920 patent for Wakix, its only approved product, indicating a proactive stance against generics and likely preventing market entry before 2030.
  • Analyst Optimism: Mizuho analyst Graig Suvannavejh described the lawsuit as a “significant positive” for Harmony, asserting that the Wakix franchise is now protected, reiterating an Outperform rating with a $50 price target, reflecting confidence in the company's growth trajectory.
  • Revenue Forecast Increase: Harmony anticipates Wakix revenues to range between $1 billion and $1.04 billion in 2026, highlighting strong market demand in the sleep disorder treatment sector, while also expanding its late-stage CNS pipeline, enhancing future growth potential.
  • Financial Performance: Harmony reported a non-GAAP EPS of $0.57, missing expectations by $0.50, yet revenue of $243.78 million exceeded forecasts by $3.46 million, indicating resilience in revenue growth despite profitability pressures.
stocktwits
7.0
04-21stocktwits
Harmony Biosciences Sues AET Pharma Over Patent Infringement
  • Patent Lawsuit Development: Harmony Biosciences has filed a lawsuit against AET Pharma for allegedly infringing a patent covering pitolisant, a move viewed by Mizuho as a significant positive for the company, expected to protect its Wakix franchise through 2030.
  • Stock Price Surge: Following the announcement of the new lawsuit by Mizuho analysts, Harmony's shares soared over 18% in Tuesday's trading, reflecting optimistic market sentiment and increased investor confidence in the company's patent protections.
  • Analyst Rating Upgrade: Mizuho reiterated its ‘Outperform’ rating on Harmony, setting a price target of $50, implying a potential upside of about 50% from current levels, further solidifying market expectations for the company's future growth.
  • Positive Market Sentiment: According to Stocktwits data, retail sentiment around Harmony is trending bullish with high message volume, indicating investor optimism regarding the company's potential in treating narcolepsy and related conditions.
Benzinga
6.0
02-25Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Updates: Top Wall Street analysts have adjusted their ratings on several companies, reflecting the latest market perspectives on these stocks, which could influence investor decisions and market trends.
  • Overview of Rating Changes: While specific upgrades and downgrades are not detailed, the overall rating changes may lead to short-term volatility in related stocks, prompting investors to stay alert.
  • Expected Market Reaction: Analyst rating adjustments typically attract market attention, potentially affecting investor confidence and trading volumes, thereby impacting stock prices.
  • Impact on Investor Decisions: Investors considering buying CAVA stock should pay attention to analysts' views to make more informed investment decisions, even though specific recommendations are not provided in this article.
seekingalpha
9.5
02-24seekingalpha
Harmony Biosciences Q4 2025 Earnings Highlights
  • Significant Revenue Growth: In Q4 2025, Harmony Biosciences reported net product revenue of $243.8 million, a 21% increase from $201.3 million in the same quarter last year, indicating strong demand in the narcolepsy market and sustained profitability.
  • Sustained Patient Growth: CEO Jeffrey Dayno highlighted that the fourth quarter saw an average addition of over 400 patients, marking the first time in franchise history, showcasing WAKIX's unique competitive advantage and future growth potential.
  • Robust Cash Flow: As of the end of Q4, the company had $882.5 million in cash, cash equivalents, and investments, ensuring funding for future R&D and market expansion, thereby enhancing financial flexibility within the industry.
  • Optimistic Outlook: Management reiterated guidance for WAKIX net revenue of $1 billion to $1.04 billion in 2026, reflecting strong confidence in the narcolepsy market and the brand's blockbuster potential.
seekingalpha
9.5
02-24seekingalpha
Harmony Biosciences Q4 Earnings Analysis
  • Earnings Performance: Harmony Biosciences reported a Q4 Non-GAAP EPS of $0.57, missing expectations by $0.50, indicating profitability challenges that could negatively impact investor confidence.
  • Revenue Growth: The company achieved Q4 revenue of $243.78 million, a 21.1% year-over-year increase, beating market expectations by $3.46 million, suggesting sustained product demand that may lay a foundation for future performance.
  • Patient Growth: The average number of patients on WAKIX increased by approximately 400 to around 8,500 in Q4, marking the third consecutive quarter of over 400 new patients, demonstrating the product's market acceptance and growth potential.
  • Future Guidance: Harmony reiterated its 2026 net revenue guidance for WAKIX at $1.0 to $1.04 billion, and despite the current earnings miss, the company's confidence in future revenues may attract long-term investor interest.
Newsfilter
9.5
02-24Newsfilter
Harmony Biosciences Reports $868.5 Million Revenue for 2025, Guidance for 2026 Exceeds $1 Billion
  • Significant Revenue Growth: Harmony Biosciences reported net product revenue of $868.5 million for 2025, reflecting a 22% year-over-year increase, driven by sustained demand for WAKIX among approximately 80,000 diagnosed narcolepsy patients, reinforcing the company's profitability and market position in the biotech sector.
  • Optimistic Future Outlook: The company reiterated its 2026 WAKIX net revenue guidance of $1.0 to $1.04 billion, indicating a trajectory towards blockbuster status, showcasing the strong market potential and ongoing momentum of the Pitolisant franchise.
  • Increased R&D Investment: Research and development expenses reached $49.9 million in Q4 2025, a 44% increase, demonstrating the company's commitment to advancing new drug development and expanding its product pipeline, particularly in the field of central nervous system disorders.
  • Market Expansion Strategy: Harmony plans to broaden the indications for Pitolisant into larger CNS conditions, which is expected to provide new revenue growth drivers in the future, especially in the management of fatigue, thereby enhancing its competitive edge in the market.
Wall Street analysts forecast HRMY stock price to rise
6 Analyst Rating
Wall Street analysts forecast HRMY stock price to rise
5 Buy
0 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
H.C. Wainwright
Patrick Trucchio
Buy
maintain
$55
AI Analysis
2026-04-23
New
Reason
H.C. Wainwright
Patrick Trucchio
Price Target
$55
AI Analysis
2026-04-23
New
maintain
Buy
Reason
H.C. Wainwright analyst Patrick Trucchio says that following an April 22 meeting with President and CEO Jeff Dayno, newly appointed CFO Glenn Reicin, and Head of Investor Relations Brennan Doyle, the firm has increased conviction that recent Harmony Biosciences weakness related to IP litigation has created an attractive buying opportunity. Wainwright expects a positive outcome from the IP litigation filed this week, which could support the transition of the WAKIX franchise to next-generation formulations. With shares down about 15% year-to-date vs. XBI up 12%, reflecting what the firm views as an excessive IP overhang, Wainwright reiterates a Buy rating and $55 price target on Harmony.
Oppenheimer
Jay Olson
Outperform
maintain
$62 -> $72
2026-04-22
New
Reason
Oppenheimer
Jay Olson
Price Target
$62 -> $72
2026-04-22
New
maintain
Outperform
Reason
Oppenheimer analyst Jay Olson raised the firm's price target on Harmony Biosciences to $72 from $62 and keeps an Outperform rating on the shares. The firm attributes yesterday's share rally to Harmony's recent patent litigation defending Wakix, which it believes "helped dispel bears" that expected loss of exclusivity before 2030. Harmony has always appeared well positioned to defend the Wakix intellectual property, the analyst tells investors in a research note.
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Valuation Metrics

The current forward P/E ratio for Harmony Biosciences Holdings Inc (HRMY.O) is 9.70, compared to its 5-year average forward P/E of 15.35. For a more detailed relative valuation and DCF analysis to assess Harmony Biosciences Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
15.35
Current PE
9.70
Overvalued PE
21.32
Undervalued PE
9.38

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
9.24
Current EV/EBITDA
6.47
Overvalued EV/EBITDA
13.18
Undervalued EV/EBITDA
5.30

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.63
Current PS
1.61
Overvalued PS
5.25
Undervalued PS
2.01

Financials

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Whales Holding HRMY

Y
Yelin Lapidot Holdings Ltd.
Holding
HRMY
+4.69%
3M Return
C
CX Institutional, LLC
Holding
HRMY
+2.22%
3M Return
T
Tang Capital Management, LLC
Holding
HRMY
+0.48%
3M Return

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Frequently Asked Questions

What is Harmony Biosciences Holdings Inc (HRMY) stock price today?

The current price of HRMY is 30.8 USD — it has decreased -3.99

What is Harmony Biosciences Holdings Inc (HRMY)'s business?

Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.

What is the price predicton of HRMY Stock?

Wall Street analysts forecast HRMY stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for HRMY is43.83 USD with a low forecast of 32.00 USD and a high forecast of 55.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Harmony Biosciences Holdings Inc (HRMY)'s revenue for the last quarter?

Harmony Biosciences Holdings Inc revenue for the last quarter amounts to 243.78M USD, increased 21.12

What is Harmony Biosciences Holdings Inc (HRMY)'s earnings per share (EPS) for the last quarter?

Harmony Biosciences Holdings Inc. EPS for the last quarter amounts to 0.39 USD, decreased -54.12

How many employees does Harmony Biosciences Holdings Inc (HRMY). have?

Harmony Biosciences Holdings Inc (HRMY) has 293 emplpoyees as of April 25 2026.

What is Harmony Biosciences Holdings Inc (HRMY) market cap?

Today HRMY has the market capitalization of 1.78B USD.