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HRMY Overview

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$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
$
0.000
0.000(0.000%)
At close
0.000(0.000%)Aft-market
ET
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Intellectia

Loading chart...

High
28.420
Open
28.280
VWAP
28.16
Vol
56.88K
Mkt Cap
1.67B
Low
28.000
Amount
1.60M
EV/EBITDA(TTM)
4.51
Total Shares
57.84M
EV
1.05B
EV/OCF(TTM)
3.03
P/S(TTM)
1.94
Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.
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Events Timeline

(ET)
2026-02-24
16:40:00
Major Averages Bounce Back, Investors Focus on AI News
select
2026-02-24
12:00:00
Major Averages Bounce Back, Investors Focus on AI News
select
2026-02-24
07:50:00
Harmony Biosciences Q4 Revenue Reaches $243.78M
select
2026-02-24
07:50:00
Harmony Biosciences Maintains FY26 Revenue View at $1B-$1.04B
select

News

Benzinga
6.0
02-25Benzinga
Wall Street Analysts Adjust Ratings
  • Analyst Rating Updates: Top Wall Street analysts have adjusted their ratings on several companies, reflecting the latest market perspectives on these stocks, which could influence investor decisions and market trends.
  • Overview of Rating Changes: While specific upgrades and downgrades are not detailed, the overall rating changes may lead to short-term volatility in related stocks, prompting investors to stay alert.
  • Expected Market Reaction: Analyst rating adjustments typically attract market attention, potentially affecting investor confidence and trading volumes, thereby impacting stock prices.
  • Impact on Investor Decisions: Investors considering buying CAVA stock should pay attention to analysts' views to make more informed investment decisions, even though specific recommendations are not provided in this article.
seekingalpha
9.5
02-24seekingalpha
Harmony Biosciences Q4 2025 Earnings Highlights
  • Significant Revenue Growth: In Q4 2025, Harmony Biosciences reported net product revenue of $243.8 million, a 21% increase from $201.3 million in the same quarter last year, indicating strong demand in the narcolepsy market and sustained profitability.
  • Sustained Patient Growth: CEO Jeffrey Dayno highlighted that the fourth quarter saw an average addition of over 400 patients, marking the first time in franchise history, showcasing WAKIX's unique competitive advantage and future growth potential.
  • Robust Cash Flow: As of the end of Q4, the company had $882.5 million in cash, cash equivalents, and investments, ensuring funding for future R&D and market expansion, thereby enhancing financial flexibility within the industry.
  • Optimistic Outlook: Management reiterated guidance for WAKIX net revenue of $1 billion to $1.04 billion in 2026, reflecting strong confidence in the narcolepsy market and the brand's blockbuster potential.
seekingalpha
9.5
02-24seekingalpha
Harmony Biosciences Q4 Earnings Analysis
  • Earnings Performance: Harmony Biosciences reported a Q4 Non-GAAP EPS of $0.57, missing expectations by $0.50, indicating profitability challenges that could negatively impact investor confidence.
  • Revenue Growth: The company achieved Q4 revenue of $243.78 million, a 21.1% year-over-year increase, beating market expectations by $3.46 million, suggesting sustained product demand that may lay a foundation for future performance.
  • Patient Growth: The average number of patients on WAKIX increased by approximately 400 to around 8,500 in Q4, marking the third consecutive quarter of over 400 new patients, demonstrating the product's market acceptance and growth potential.
  • Future Guidance: Harmony reiterated its 2026 net revenue guidance for WAKIX at $1.0 to $1.04 billion, and despite the current earnings miss, the company's confidence in future revenues may attract long-term investor interest.
Newsfilter
9.5
02-24Newsfilter
Harmony Biosciences Reports $868.5 Million Revenue for 2025, Guidance for 2026 Exceeds $1 Billion
  • Significant Revenue Growth: Harmony Biosciences reported net product revenue of $868.5 million for 2025, reflecting a 22% year-over-year increase, driven by sustained demand for WAKIX among approximately 80,000 diagnosed narcolepsy patients, reinforcing the company's profitability and market position in the biotech sector.
  • Optimistic Future Outlook: The company reiterated its 2026 WAKIX net revenue guidance of $1.0 to $1.04 billion, indicating a trajectory towards blockbuster status, showcasing the strong market potential and ongoing momentum of the Pitolisant franchise.
  • Increased R&D Investment: Research and development expenses reached $49.9 million in Q4 2025, a 44% increase, demonstrating the company's commitment to advancing new drug development and expanding its product pipeline, particularly in the field of central nervous system disorders.
  • Market Expansion Strategy: Harmony plans to broaden the indications for Pitolisant into larger CNS conditions, which is expected to provide new revenue growth drivers in the future, especially in the management of fatigue, thereby enhancing its competitive edge in the market.
seekingalpha
6.0
02-23seekingalpha
Harmony Biosciences Downgraded, Shares Drop 10%
  • Rating Downgrade Impact: Deutsche Bank and Truist downgraded Harmony Biosciences from buy to hold, resulting in a ~10% drop in stock price during Monday trading, reflecting market concerns about the company's future performance.
  • Intellectual Property Case Risk: Analysts highlighted that Harmony's main drug, Wakix (pitolisant), faces an intellectual property case with AET Pharma, with indications that the judge may be siding against Harmony; if exclusivity is lost, generics could enter the market as early as this year instead of 2030.
  • Market Outlook Uncertainty: Truist's analyst noted that the judge's initial comments following the trial do not bode well for HRMY, increasing uncertainty around the durability of the Wakix franchise, which could impact the company's overall valuation.
  • Single Value Driver: As Wakix remains the sole value driver for Harmony, concerns about its future prompted the downgrade, indicating a lack of confidence in the company's profitability moving forward.
seekingalpha
9.5
02-23seekingalpha
Harmony Biosciences to Announce Q4 Earnings on February 24
  • Earnings Announcement Date: Harmony Biosciences Holdings, Inc. is set to release its Q4 2023 earnings on February 24 before market open, with a consensus EPS estimate of $1.07, reflecting a slight decline of 0.9% year-over-year, indicating potential challenges in profitability.
  • Revenue Growth Expectations: The revenue estimate for the quarter stands at $240.32 million, representing a robust year-over-year growth of 19.4%, suggesting strong market demand and sales performance that could lay the groundwork for future growth.
  • Historical Performance Review: Over the past two years, Harmony Biosciences has exceeded EPS estimates 75% of the time and revenue estimates 63% of the time, indicating a relatively stable financial performance that enhances investor confidence.
  • Expectation Revision Dynamics: In the last three months, EPS estimates have seen two upward revisions and one downward revision, while revenue estimates have experienced seven upward revisions with no downward adjustments, reflecting analysts' optimistic outlook on the company's future performance, which may influence stock price movements.
Wall Street analysts forecast HRMY stock price to rise
6 Analyst Rating
Wall Street analysts forecast HRMY stock price to rise
5 Buy
0 Hold
1 Sell
Moderate Buy
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
Current: 0.000
sliders
Low
32.00
Averages
43.83
High
55.00
UBS
So Youn Shim
Neutral
downgrade
$46 -> $36
AI Analysis
2026-02-25
Reason
UBS
So Youn Shim
Price Target
$46 -> $36
AI Analysis
2026-02-25
downgrade
Neutral
Reason
UBS analyst So Youn Shim lowered the firm's price target on Harmony Biosciences to $36 from $46 and keeps a Neutral rating on the shares. The stock rebounded 5% after a 25% decline last week, likely investor optimism around additional ANDA settlements with three Wakix generic filers, the analyst tells investors in a research note. Under the new agreements, generics can launch in September 2029, four months earlier than prior settlements and upside exists if Harmony wins both Wakix patents and secures the pediatric exclusivity extension, while downside risk includes potential multi-source generic entry as early as 3Q26 if both patents are lost, the firm says.
Deutsche Bank
David Hoang
Hold
downgrade
$31 -> $30
2026-02-25
Reason
Deutsche Bank
David Hoang
Price Target
$31 -> $30
2026-02-25
downgrade
Hold
Reason
Deutsche Bank analyst David Hoang lowered the firm's price target on Harmony Biosciences to $30 from $31 and keeps a Hold rating on the shares. The firm updated the company's model post the Q4 report.
Unlock Full Analyst Thesis, Get the complete breakdown of rating reason for HRMY
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Valuation Metrics

The current forward P/E ratio for Harmony Biosciences Holdings Inc (HRMY.O) is 10.04, compared to its 5-year average forward P/E of 16.31. For a more detailed relative valuation and DCF analysis to assess Harmony Biosciences Holdings Inc's fair value, Click here.

Forward PE

The forward P/E ratio is a valuation metric that divides a company's current stock price by its estimated future earnings per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PE
16.31
Current PE
10.04
Overvalued PE
22.95
Undervalued PE
9.67

Forward EV/EBITDA

The forward EV/EBITDA ratio is a valuation metric that divides a company's enterprise value (EV) by its estimated future earnings before interest, taxes, depreciation, and amortization (EBITDA) over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average EV/EBITDA
9.64
Current EV/EBITDA
5.85
Overvalued EV/EBITDA
13.54
Undervalued EV/EBITDA
5.74

Forward PS

The forward P/S ratio is a valuation metric that divides a company's current stock price by its estimated future sales (or revenue) per share over the next 12 months.
StronglyUndervaluedUndervaluedFairOvervaluedStronglyOvervalueddotted line Image
5Y Average PS
3.80
Current PS
2.23
Overvalued PS
5.38
Undervalued PS
2.22

Financials

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Whales Holding HRMY

T
Tang Capital Management, LLC
Holding
HRMY
+2.62%
3M Return
Y
Yelin Lapidot Holdings Ltd.
Holding
HRMY
-1.38%
3M Return

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Frequently Asked Questions

What is Harmony Biosciences Holdings Inc (HRMY) stock price today?

The current price of HRMY is 28.06 USD — it has decreased -2.54

What is Harmony Biosciences Holdings Inc (HRMY)'s business?

Harmony Biosciences Holdings, Inc. is a pharmaceutical company. It is focused on developing and commercializing therapies for patients living with rare neurological diseases as well as patients living with other neurological diseases who have unmet medical needs. Its product, WAKIX (pitolisant), is a first-in-class molecule with a novel mechanism of action designed to enhance histamine signaling in the brain by binding to H3 receptors. WAKIX was developed for the treatment of excessive daytime sleepiness (EDS) in pediatric patients, six years and older, with narcolepsy. HBS-102, an investigational compound, which is a melanin-concentrating hormone receptor 1 (MCHR1) antagonist. ZYN002 is an investigational drug product in development for the potential treatment of behavioral symptoms associated with Fragile X syndrome (FXS) and 22q11.2 deletion syndrome (22q). It also focused on the rare epilepsy franchise in its expanding late-stage pipeline of CNS assets: EPX-100 and EPX-200.

What is the price predicton of HRMY Stock?

Wall Street analysts forecast HRMY stock price to rise over the next 12 months. According to Wall Street analysts, the average 1-year price target for HRMY is43.83 USD with a low forecast of 32.00 USD and a high forecast of 55.00 USD. However, analyst price targets are subjective and often lag stock prices, so investors should focus on the objective reasons behind analyst rating changes, which better reflect the company's fundamentals.

What is Harmony Biosciences Holdings Inc (HRMY)'s revenue for the last quarter?

Harmony Biosciences Holdings Inc revenue for the last quarter amounts to 243.78M USD, increased 21.12

What is Harmony Biosciences Holdings Inc (HRMY)'s earnings per share (EPS) for the last quarter?

Harmony Biosciences Holdings Inc. EPS for the last quarter amounts to 0.39 USD, decreased -54.12

How many employees does Harmony Biosciences Holdings Inc (HRMY). have?

Harmony Biosciences Holdings Inc (HRMY) has 293 emplpoyees as of March 12 2026.

What is Harmony Biosciences Holdings Inc (HRMY) market cap?

Today HRMY has the market capitalization of 1.67B USD.